Your Input: | |
| | Bsel_0095 | RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: hip:CGSHiEE_09090 RNA polymerase sigma factor RpoE; TIGRFAM: RNA polymerase sigma-H factor; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2. (214 aa) |
| | Bsel_0096 | RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: pfo:Pfl01_0184 RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; Belongs to the sigma-70 factor family. ECF subfamily. (184 aa) |
| | nusG | NusG antitermination factor; Participates in transcription elongation, termination and antitermination. (177 aa) |
| | rpoB | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1181 aa) |
| | rpoC | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1201 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (217 aa) |
| | rpoA | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (314 aa) |
| | Bsel_0150 | PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: neu:NE2190 integron/retron-type RNA-directed DNA polymerase. (422 aa) |
| | Bsel_0215 | KEGG: mxa:MXAN_4309 ECF subfamily RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein. (185 aa) |
| | Bsel_0302 | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (163 aa) |
| | Bsel_0305 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (347 aa) |
| | Bsel_0319 | RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: afw:Anae109_0489 RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily. (166 aa) |
| | Bsel_0370 | KEGG: ank:AnaeK_2178 RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-W factor; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein. (187 aa) |
| | dacA | Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (272 aa) |
| | Bsel_0402 | RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: bbt:BBta_3011 RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; Belongs to the sigma-70 factor family. ECF subfamily. (181 aa) |
| | Bsel_0404 | PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: neu:NE2190 integron/retron-type RNA-directed DNA polymerase. (422 aa) |
| | Bsel_0515 | RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: pca:Pcar_3124 RNA polymerase, sigma-E factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; Belongs to the sigma-70 factor family. ECF subfamily. (178 aa) |
| | Bsel_0539 | Transcriptional regulator, LuxR family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (268 aa) |
| | Bsel_0647 | RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: sde:Sde_0297 RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily. (185 aa) |
| | guaA | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (512 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (161 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (381 aa) |
| | Bsel_0690 | KEGG: gur:Gura_2064 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (432 aa) |
| | purC | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: hhe:HH1619 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. (237 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (86 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (227 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (743 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (474 aa) |
| | purM | TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; KEGG: mlo:mll7962 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. (348 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (192 aa) |
| | purH | SMART: AICARFT/IMPCHase bienzyme formylation region; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: apj:APJL_0971 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein. (512 aa) |
| | purD | TIGRFAM: phosphoribosylamine/glycine ligase; KEGG: vfm:VFMJ11_2513 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; protein of unknown function DUF201; ATP-grasp domain protein; Belongs to the GARS family. (422 aa) |
| | Bsel_0766 | Putative RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; PFAM: Sigma-70 region 4 type 2; KEGG: hypothetical protein. (133 aa) |
| | Bsel_0771 | SMART: DNA-directed DNA polymerase; KEGG: xfa:XF2525 phage-related DNA polymerase. (644 aa) |
| | Bsel_0776 | Hypothetical protein. (143 aa) |
| | Bsel_0778 | RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: scl:sce1879 ECF family RNA polymerase sigma factor. (141 aa) |
| | dcd | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (194 aa) |
| | Bsel_1111 | KEGG: bba:Bd0843 RNA polymerase sigma-54 factor; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor. (444 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa) |
| | Bsel_1265 | KEGG: ccv:CCV52592_0623 nicotinate phosphoribosyltransferase; Belongs to the NAPRTase family. (372 aa) |
| | nadK | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (265 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa) |
| | Bsel_1344 | TIGRFAM: DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; KEGG: sfu:Sfum_1225 DNA polymerase III, alpha subunit; SMART: phosphoesterase PHP domain protein. (1126 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (289 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (328 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. (878 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (200 aa) |
| | Bsel_1365 | PFAM: replication initiation and membrane attachment family protein. (481 aa) |
| | Bsel_1387 | KEGG: geo:Geob_1150 PHP domain protein; PFAM: PHP domain protein; SMART: DNA polymerase X; phosphoesterase PHP domain protein. (575 aa) |
| | Bsel_1554 | PFAM: RelA/SpoT domain protein; KEGG: pfs:PFLU1597 hypothetical protein. (213 aa) |
| | nadK-2 | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (262 aa) |
| | Bsel_1572 | RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: bja:blr2557 RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily. (184 aa) |
| | Bsel_1583 | PFAM: GCN5-related N-acetyltransferase; KEGG: abo:ABO_1271 acetyltransferase. (144 aa) |
| | Bsel_1598 | PFAM: protein of unknown function DUF1447. (70 aa) |
| | coaD | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (164 aa) |
| | pyrR | Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. (182 aa) |
| | pyrB | TIGRFAM: aspartate carbamoyltransferase; KEGG: gem:GM21_2312 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (300 aa) |
| | pyrC | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (428 aa) |
| | carA | KEGG: pca:Pcar_1613 carbamoyl phosphate synthase small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family. (365 aa) |
| | carB | KEGG: dal:Dalk_3481 carbamoyl-phosphate synthase, large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; RimK domain protein ATP-grasp; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; Belongs to the CarB family. (1071 aa) |
| | pyrK | Oxidoreductase FAD/NAD(P)-binding domain protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (251 aa) |
| | pyrD | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. (311 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (239 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (213 aa) |
| | Bsel_1681 | PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: neu:NE2190 integron/retron-type RNA-directed DNA polymerase. (422 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (203 aa) |
| | rpoZ | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (135 aa) |
| | Bsel_1690 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (403 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (808 aa) |
| | Bsel_1744 | SMART: AAA ATPase; TIGRFAM: flagellar protein export ATPase FliI; ATPase, FliI/YscN family; KEGG: sat:SYN_01473 flagellum-specific ATP synthase; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein. (434 aa) |
| | Bsel_1770 | KEGG: gem:GM21_3848 RNA polymerase, sigma 28 subunit, FliA/WhiG; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; sigma-70 region 3 domain protein; Sigma-70 region 4 type 2. (253 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (243 aa) |
| | polC | DNA polymerase III, alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1433 aa) |
| | nusA | NusA antitermination factor; Participates in both transcription termination and antitermination. (396 aa) |
| | Bsel_1792 | KEGG: sfu:Sfum_3182 riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; Belongs to the ribF family. (317 aa) |
| | Bsel_1800 | PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: neu:NE2190 integron/retron-type RNA-directed DNA polymerase. (422 aa) |
| | cinA | KEGG: dds:Ddes_1466 competence/damage-inducible protein CinA; TIGRFAM: competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; Belongs to the CinA family. (412 aa) |
| | selA | L-seryl-tRNA selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (473 aa) |
| | nadE | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (274 aa) |
| | Bsel_1909 | SMART: Exonuclease; TIGRFAM: DNA polymerase III, epsilon subunit; KEGG: lch:Lcho_0238 DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III. (242 aa) |
| | Bsel_1937 | KEGG: rfr:Rfer_3777 DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease. (233 aa) |
| | Bsel_1943 | PFAM: amino acid-binding ACT domain protein; KEGG: cco:CCC13826_1470 hypothetical protein; Belongs to the UPF0237 family. (91 aa) |
| | carB-2 | KEGG: ppd:Ppro_2524 carbamoyl-phosphate synthase, large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; RimK domain protein ATP-grasp; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein. (1079 aa) |
| | carA-2 | KEGG: pca:Pcar_1613 carbamoyl phosphate synthase small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (364 aa) |
| | prs-2 | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (317 aa) |
| | Bsel_2020 | KEGG: geo:Geob_3171 DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; Belongs to the DNA polymerase type-Y family. (421 aa) |
| | Bsel_2031 | PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: neu:NE2190 integron/retron-type RNA-directed DNA polymerase. (422 aa) |
| | Bsel_2066 | PFAM: deoxynucleoside kinase; KEGG: abo:ABO_0338 deoxynucleoside kinase. (217 aa) |
| | Bsel_2067 | PFAM: deoxynucleoside kinase; KEGG: hypothetical protein. (228 aa) |
| | Bsel_2094 | TIGRFAM: primosome, DnaD subunit; PFAM: DnaD and phage-associated region. (237 aa) |
| | dinG | DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease. (935 aa) |
| | ndk | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (135 aa) |
| | Bsel_2137 | PFAM: tryptophan RNA-binding attenuator protein. (72 aa) |
| | cmk | KEGG: pmu:PM0802 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. (226 aa) |
| | dinB | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (429 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (287 aa) |
| | nusB | NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (134 aa) |
| | Bsel_2272 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (453 aa) |
| | sigA | RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (371 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (604 aa) |
| | Bsel_2374 | KEGG: geo:Geob_2173 DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta. (343 aa) |
| | Bsel_2380 | PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region. (192 aa) |
| | nadD | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (191 aa) |
| | udk | TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: similar to uridine-cytidine kinase 2; SMART: AAA ATPase. (211 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (170 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (379 aa) |
| | queA | S-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (351 aa) |
| | Bsel_2564 | TIGRFAM: iron-sulfur cluster binding protein; PFAM: domain of unknown function DUF1730; 4Fe-4S ferredoxin iron-sulfur binding domain protein; PBS lyase HEAT domain protein repeat-containing protein; KEGG: oan:Oant_1337 hypothetical protein; SMART: PBS lyase HEAT domain protein repeat-containing protein. (397 aa) |
| | Bsel_2587 | PFAM: RelA/SpoT domain protein; KEGG: aha:AHA_3012 region found in RelA / SpoT proteins. (271 aa) |
| | Bsel_2601 | KEGG: ppu:PP_2995 DNA topology modulation kinase FlaR, putative. (175 aa) |
| | queE | 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (243 aa) |
| | Bsel_2636 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: apa:APP7_1154 putative 6-pyruvoyl tetrahydrobiopterin synthase. (160 aa) |
| | queC | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). (219 aa) |
| | Bsel_2660 | PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: neu:NE2190 integron/retron-type RNA-directed DNA polymerase. (422 aa) |
| | Bsel_2809 | PFAM: GCN5-related N-acetyltransferase; KEGG: saz:Sama_0404 acetyltransferase. (148 aa) |
| | Bsel_2822 | KEGG: bxe:Bxe_A0905 guanylate kinase; PFAM: guanylate kinase; SMART: guanylate kinase/L-type calcium channel region. (189 aa) |
| | Bsel_2906 | TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: swd:Swoo_3818 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (182 aa) |
| | Bsel_2965 | Putative RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; PFAM: sigma-70 region 4 domain protein; KEGG: cco:CCC13826_1021 flagellar biosynthesis sigma factor. (156 aa) |
| | Bsel_3017 | Putative RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; PFAM: Sigma-70 region 4 type 2. (141 aa) |
| | Bsel_3019 | Hypothetical protein. (143 aa) |
| | Bsel_3024 | KEGG: ecr:ECIAI1_2664 putative DNA polymerase from bacteriophage origin; PFAM: DNA-directed DNA polymerase; SMART: DNA-directed DNA polymerase. (655 aa) |
| | Bsel_3029 | Putative RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; PFAM: sigma-70 region 4 domain protein; KEGG: cco:CCC13826_1021 flagellar biosynthesis sigma factor. (156 aa) |
| | Bsel_3032 | TIGRFAM: nucleotide sugar dehydrogenase; KEGG: vfm:VFMJ11_0190 udp-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. (388 aa) |
| | Bsel_3035 | TIGRFAM: nucleotide sugar dehydrogenase; KEGG: bja:bll8129 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. (454 aa) |
| | Bsel_3049 | RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; KEGG: tbd:Tbd_1180 RNA polymerase sigma-70 factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein. (175 aa) |
| | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (438 aa) |
| | atpC | ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (134 aa) |
| | atpD | ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (472 aa) |
| | atpG | ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (294 aa) |
| | atpA | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (501 aa) |
| | atpH | ATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (184 aa) |
| | atpF | ATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (165 aa) |
| | atpE | ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (73 aa) |
| | atpB | ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (241 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa) |
| | tdk | KEGG: mxa:MXAN_5072 thymidine kinase; PFAM: thymidine kinase. (209 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (427 aa) |
| | murA-2 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (429 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (538 aa) |
| | rpoE | DNA-directed RNA polymerase delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. (174 aa) |
| | Bsel_3220 | Conserved hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (225 aa) |
| | Bsel_3221 | KEGG: dde:Dde_3241 phosphate acetyltransferase; TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase. (325 aa) |
| | coaA | TIGRFAM: pantothenate kinase; KEGG: pla:Plav_1229 pantothenate kinase. (316 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (429 aa) |
| | Bsel_3305 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (453 aa) |
| | Bsel_0002 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (380 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (424 aa) |
| | dnaX | DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (600 aa) |
| | queF | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (135 aa) |
| | Bsel_0028 | Conserved hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (215 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (210 aa) |
| | Bsel_0036 | KEGG: geo:Geob_2151 DNA polymerase III, delta prime subunit; TIGRFAM: DNA polymerase III, delta prime subunit. (330 aa) |
| | glmU | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (452 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (316 aa) |
| | Bsel_0065 | TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: dps:DP0449 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (180 aa) |
| | coaX | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (255 aa) |
