STRINGSTRING
kdsB kdsB Oant_0167 Oant_0167 Oant_0168 Oant_0168 Oant_0169 Oant_0169 Oant_0341 Oant_0341 Oant_0342 Oant_0342 Oant_0375 Oant_0375 Oant_0376 Oant_0376 Oant_0489 Oant_0489 Oant_0490 Oant_0490 Oant_0491 Oant_0491 Oant_0961 Oant_0961 tolQ tolQ Oant_1216 Oant_1216 Oant_1217 Oant_1217 tolB tolB Oant_1219 Oant_1219 pal pal cpoB cpoB tilS tilS Oant_1254 Oant_1254 Oant_1255 Oant_1255 Oant_1256 Oant_1256 Oant_1257 Oant_1257 macB macB Oant_1259 Oant_1259 Oant_1651 Oant_1651 Oant_1652 Oant_1652 lpxC lpxC bamD bamD Oant_1983 Oant_1983 Oant_1984 Oant_1984 Oant_1985 Oant_1985 bamA bamA lpxD lpxD lpxA lpxA Oant_2040 Oant_2040 Oant_2041 Oant_2041 Oant_2050 Oant_2050 kdsA kdsA Oant_2173 Oant_2173 Oant_2174 Oant_2174 Oant_2243 Oant_2243 Oant_2375 Oant_2375 lolD lolD Oant_2404 Oant_2404 Oant_2433 Oant_2433 Oant_2434 Oant_2434 Oant_2523 Oant_2523 Oant_2601 Oant_2601 Oant_2602 Oant_2602 lptD lptD Oant_2877 Oant_2877 Oant_2878 Oant_2878 Oant_3045 Oant_3045 Oant_3046 Oant_3046 lpxK lpxK Oant_3509 Oant_3509 macB-2 macB-2 Oant_3559 Oant_3559 Oant_3560 Oant_3560 Oant_4053 Oant_4053 Oant_4054 Oant_4054 Oant_4269 Oant_4269
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
kdsB3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (249 aa)
Oant_0167PFAM: protein of unknown function DUF1239; KEGG: bmb:BruAb1_0151 hypothetical protein. (237 aa)
Oant_0168PFAM: OstA family protein; KEGG: bmb:BruAb1_0152 hypothetical protein. (216 aa)
Oant_0169PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bmb:BruAb1_0153 ABC transporter, ATP-binding protein. (279 aa)
Oant_0341TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: bms:BR0276 transporter, putative; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (375 aa)
Oant_0342PFAM: acriflavin resistance protein; KEGG: bms:BR0277 AcrB/AcrD/AcrF multidrug efflux protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1050 aa)
Oant_0375TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: bms:BR0291 HlyD family secretion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (404 aa)
Oant_0376TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: bmb:BruAb1_0318 hydrophobe/amphiphile efflux-1 family protein. (1049 aa)
Oant_0489KEGG: rme:Rmet_4957 hypothetical protein. (230 aa)
Oant_0490PFAM: OmpA/MotB domain protein; KEGG: bpa:BPP2398 putative lipoprotein. (200 aa)
Oant_0491KEGG: bpe:BP2020 hypothetical protein. (162 aa)
Oant_0961Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (230 aa)
tolQTol-Pal system TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (236 aa)
Oant_1216TIGRFAM: Biopolymer transport TolR; PFAM: Biopolymer transport protein ExbD/TolR; KEGG: bmb:BruAb1_1684 TonB system transport protein, ExbD/TolR family. (150 aa)
Oant_1217KEGG: bms:BR1698 TolA protein. (356 aa)
tolBTol-Pal system beta propeller repeat TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (443 aa)
Oant_1219Hypothetical protein. (92 aa)
palPeptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (168 aa)
cpoBTol-Pal system YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (505 aa)
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (456 aa)
Oant_1254TIGRFAM: TonB-system energizer ExbB type-1; PFAM: MotA/TolQ/ExbB proton channel; KEGG: bmb:BruAb1_1653 ExbB, biopolymer transport protein ExbB. (338 aa)
Oant_1255TIGRFAM: TonB system transport protein ExbD type-1; PFAM: Biopolymer transport protein ExbD/TolR; KEGG: bms:BR1667 TonB system transport protein ExbD. (169 aa)
Oant_1256TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (325 aa)
Oant_1257KEGG: rle:RL2991 hypothetical protein. (258 aa)
macBABC transporter related; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (652 aa)
Oant_1259TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: bmb:BruAb1_1658 HlyD family secretion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (415 aa)
Oant_1651PFAM: Sporulation domain protein; Lytic transglycosylase catalytic; KEGG: mlo:mll3791 transglycosylase. (299 aa)
Oant_1652PFAM: protease inhibitor Kazal-type; KEGG: sme:SMc04226 hypothetical lipoprotein transmembrane. (149 aa)
lpxCUDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (312 aa)
bamDComL, hypothetical competence protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (287 aa)
Oant_1983PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: bme:BMEI0784 ATPase associated with chromosome architecture/replication. (438 aa)
Oant_1984PFAM: Lytic transglycosylase catalytic; KEGG: bme:BMEI0785 transcriptional regulatory protein. (194 aa)
Oant_1985PFAM: OmpA/MotB domain protein; 17 kDa surface antigen; KEGG: bms:BR1204 OmpA family protein. (221 aa)
bamASurface antigen (D15); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (785 aa)
lpxDUDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (352 aa)
lpxAacyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (278 aa)
Oant_2040PFAM: protein of unknown function DUF1009; KEGG: bmb:BruAb1_1156 conserved hypothetical protein TIGR00148. (299 aa)
Oant_2041lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (394 aa)
Oant_2050KEGG: bms:BR1139 rotamase family protein. (628 aa)
kdsATIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: bme:BMEI0850 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase). (277 aa)
Oant_2173PFAM: acriflavin resistance protein; KEGG: bmb:BruAb1_1094 AcrB/AcrD/AcrF multidrug efflux protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1029 aa)
Oant_2174TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: bms:BR1089 hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (394 aa)
Oant_2243TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein; KEGG: bmb:BruAb1_0954 outer membrane efflux family protein. (455 aa)
Oant_2375PFAM: lipid A biosynthesis acyltransferase; KEGG: bmb:BruAb1_0863 lipid A biosynthesis lauroyl acyltransferase, hypothetical. (308 aa)
lolDABC transporter related; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (227 aa)
Oant_2404TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: bms:BR0823 ABC transporter, permease protein. (438 aa)
Oant_2433TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: mlo:mll6730 multidrug-efflux transport protein. (1051 aa)
Oant_2434TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: mlo:mll6731 multidrug efflux membrane fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (383 aa)
Oant_2523PFAM: SmpA/OmlA domain protein; KEGG: bms:BR0772 hypothetical protein. (174 aa)
Oant_2601PFAM: permease YjgP/YjgQ family protein; KEGG: bms:BR0687 hypothetical protein. (402 aa)
Oant_2602PFAM: permease YjgP/YjgQ family protein; KEGG: bms:BR0686 hypothetical protein. (362 aa)
lptDOrganic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family. (786 aa)
Oant_2877TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: sme:SMc01095 probable multidrug-efflux system transmembrane protein. (1061 aa)
Oant_2878TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: sme:SMc01094 putative multidrug efflux system transmembrane protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (396 aa)
Oant_3045PFAM: protein of unknown function DUF374; KEGG: bmb:BruAb2_0210 hypothetical protein. (268 aa)
Oant_3046Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (446 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (341 aa)
Oant_3509PFAM: OmpA/MotB domain protein; KEGG: sme:SMc00141 hypothetical protein. (742 aa)
macB-2ABC transporter related; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (653 aa)
Oant_3559TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: rpc:RPC_1868 secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (396 aa)
Oant_3560TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: rpb:RPB_2240 RND efflux system, outer membrane lipoprotein, NodT. (493 aa)
Oant_4053TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shw:Sputw3181_1129 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (414 aa)
Oant_4054TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: rpd:RPD_2310 hydrophobe/amphiphile efflux-1 HAE1. (1057 aa)
Oant_4269TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: bme:BMEII0021 polysialic acid capsule expression protein KpsF; Belongs to the SIS family. GutQ/KpsF subfamily. (354 aa)
Your Current Organism:
Ochrobactrum anthropi
NCBI taxonomy Id: 439375
Other names: O. anthropi ATCC 49188, Ochrobactrum anthropi ATCC 49188, Ochrobactrum anthropi DSM 6882, Ochrobactrum anthropi LMG 3331, Ochrobactrum anthropi str. ATCC 49188, Ochrobactrum anthropi strain ATCC 49188
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