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kdsB kdsB Oant_0167 Oant_0167 Oant_0168 Oant_0168 Oant_0169 Oant_0169 lpxC lpxC bamD bamD bamA bamA lpxD lpxD lpxA lpxA Oant_2040 Oant_2040 Oant_2041 Oant_2041 Oant_2050 Oant_2050 kdsA kdsA Oant_2375 Oant_2375 Oant_2523 Oant_2523 Oant_2601 Oant_2601 Oant_2602 Oant_2602 lptD lptD Oant_3045 Oant_3045 Oant_3046 Oant_3046 lpxK lpxK Oant_4269 Oant_4269
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
kdsB3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (249 aa)
Oant_0167PFAM: protein of unknown function DUF1239; KEGG: bmb:BruAb1_0151 hypothetical protein. (237 aa)
Oant_0168PFAM: OstA family protein; KEGG: bmb:BruAb1_0152 hypothetical protein. (216 aa)
Oant_0169PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bmb:BruAb1_0153 ABC transporter, ATP-binding protein. (279 aa)
lpxCUDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (312 aa)
bamDComL, hypothetical competence protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (287 aa)
bamASurface antigen (D15); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (785 aa)
lpxDUDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (352 aa)
lpxAacyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (278 aa)
Oant_2040PFAM: protein of unknown function DUF1009; KEGG: bmb:BruAb1_1156 conserved hypothetical protein TIGR00148. (299 aa)
Oant_2041lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (394 aa)
Oant_2050KEGG: bms:BR1139 rotamase family protein. (628 aa)
kdsATIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: bme:BMEI0850 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase). (277 aa)
Oant_2375PFAM: lipid A biosynthesis acyltransferase; KEGG: bmb:BruAb1_0863 lipid A biosynthesis lauroyl acyltransferase, hypothetical. (308 aa)
Oant_2523PFAM: SmpA/OmlA domain protein; KEGG: bms:BR0772 hypothetical protein. (174 aa)
Oant_2601PFAM: permease YjgP/YjgQ family protein; KEGG: bms:BR0687 hypothetical protein. (402 aa)
Oant_2602PFAM: permease YjgP/YjgQ family protein; KEGG: bms:BR0686 hypothetical protein. (362 aa)
lptDOrganic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family. (786 aa)
Oant_3045PFAM: protein of unknown function DUF374; KEGG: bmb:BruAb2_0210 hypothetical protein. (268 aa)
Oant_3046Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (446 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (341 aa)
Oant_4269TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: bme:BMEII0021 polysialic acid capsule expression protein KpsF; Belongs to the SIS family. GutQ/KpsF subfamily. (354 aa)
Your Current Organism:
Ochrobactrum anthropi
NCBI taxonomy Id: 439375
Other names: O. anthropi ATCC 49188, Ochrobactrum anthropi ATCC 49188, Ochrobactrum anthropi DSM 6882, Ochrobactrum anthropi LMG 3331, Ochrobactrum anthropi str. ATCC 49188, Ochrobactrum anthropi strain ATCC 49188
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