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Oant_2074 Oant_2074 Oant_2041 Oant_2041 Oant_2040 Oant_2040 lpxA lpxA fabZ fabZ lpxD lpxD Oant_2034 Oant_2034 lpxC lpxC Oant_1715 Oant_1715 Oant_1323 Oant_1323 ispG ispG Oant_0987 Oant_0987 gpsA gpsA ispH ispH Oant_0557 Oant_0557 psd psd ispE ispE cysQ cysQ plsY plsY glmU glmU Oant_3634 Oant_3634 Oant_3175 Oant_3175 lpxK lpxK Oant_3043 Oant_3043 Oant_2966 Oant_2966 Oant_2886 Oant_2886 Oant_2882 Oant_2882 Oant_2590 Oant_2590 plsX plsX Oant_2371 Oant_2371 Oant_2104 Oant_2104 Oant_2096 Oant_2096 ispDF ispDF
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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from curated databases
experimentally determined
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Oant_2074PFAM: diacylglycerol kinase catalytic region; KEGG: eca:ECA2839 putative diacylglycerol kinase. (298 aa)
Oant_2041lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (394 aa)
Oant_2040PFAM: protein of unknown function DUF1009; KEGG: bmb:BruAb1_1156 conserved hypothetical protein TIGR00148. (299 aa)
lpxAacyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (278 aa)
fabZBeta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (157 aa)
lpxDUDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (352 aa)
Oant_2034PFAM: phosphatidate cytidylyltransferase; KEGG: bms:BR1157 phosphatidate cytidylyltransferase; Belongs to the CDS family. (270 aa)
lpxCUDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (312 aa)
Oant_1715PFAM: lipid A biosynthesis domain protein; KEGG: mlo:mlr0010 hypothetical protein. (109 aa)
Oant_1323Phospholipase D/Transphosphatidylase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (486 aa)
ispG1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (423 aa)
Oant_0987PFAM: phospholipid/glycerol acyltransferase; KEGG: bms:BR1994 1-acyl-sn-glycerol-3-phosphate acyltransferase, putative. (260 aa)
gpsAGlycerol-3-phosphate dehydrogenase (NAD(P)(+)); PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Ketopantoate reductase ApbA/PanE domain protein; KEGG: bmb:BruAb1_1866 GpsA, glycerol-3-phosphate dehydrogenase, NAD-dependent. (329 aa)
ispHHydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (350 aa)
Oant_0557PFAM: CDP-alcohol phosphatidyltransferase; KEGG: bmb:BruAb1_0466 PssA, CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (283 aa)
psdPhosphatidylserine decarboxylase related protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (232 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (289 aa)
cysQ3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (281 aa)
plsYProtein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (201 aa)
glmUNucleotidyl transferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (454 aa)
Oant_3634Phosphatidylcholine synthase; Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (287 aa)
Oant_3175KEGG: nwi:Nwi_2129 hypothetical protein. (347 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (341 aa)
Oant_3043PFAM: inositol monophosphatase; KEGG: bme:BMEII1032 myo-inositol-1(or 4)-monophosphatase. (265 aa)
Oant_2966KEGG: bmb:BruAb2_0378 hypothetical membrane protein. (139 aa)
Oant_2886PFAM: phospholipid/glycerol acyltransferase; KEGG: pae:PA2537 probable acyltransferase. (217 aa)
Oant_2882PFAM: CDP-alcohol phosphatidyltransferase; KEGG: ret:RHE_CH03135 probable CDP-alcohol phosphatidyltransferase protein. (201 aa)
Oant_2590TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: bmb:BruAb1_0717 PgsA, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (194 aa)
plsXFatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (352 aa)
Oant_2371PFAM: phosphopantetheine-binding; KEGG: bmb:BruAb1_0867 acyl carrier protein. (93 aa)
Oant_2104PFAM: metallophosphoesterase; KEGG: mlo:mll0806 hypothetical protein. (288 aa)
Oant_2096Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (116 aa)
ispDF2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. (407 aa)
Your Current Organism:
Ochrobactrum anthropi
NCBI taxonomy Id: 439375
Other names: O. anthropi ATCC 49188, Ochrobactrum anthropi ATCC 49188, Ochrobactrum anthropi DSM 6882, Ochrobactrum anthropi LMG 3331, Ochrobactrum anthropi str. ATCC 49188, Ochrobactrum anthropi strain ATCC 49188
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