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murG murG Oant_0077 Oant_0077 pncB pncB Oant_0131 Oant_0131 Oant_0243 Oant_0243 Oant_0307 Oant_0307 Oant_0391 Oant_0391 Oant_0392 Oant_0392 Oant_0415 Oant_0415 Oant_0416 Oant_0416 Oant_0417 Oant_0417 Oant_0431 Oant_0431 purF purF mltG mltG Oant_0674 Oant_0674 Oant_0698 Oant_0698 rlpA rlpA hisF hisF hisH hisH Oant_0842 Oant_0842 Oant_0995 Oant_0995 Oant_1028 Oant_1028 mtgA mtgA upp upp Oant_1492 Oant_1492 apt apt prs prs Oant_1637 Oant_1637 lgt lgt Oant_1661 Oant_1661 Oant_1715 Oant_1715 Oant_1716 Oant_1716 Oant_1733 Oant_1733 Oant_1743 Oant_1743 Oant_1869 Oant_1869 Oant_2041 Oant_2041 trpD trpD rlpA-2 rlpA-2 Oant_2105 Oant_2105 gpt gpt tgt tgt queA queA Oant_2266 Oant_2266 cobT cobT Oant_2452 Oant_2452 Oant_2507 Oant_2507 pyrE pyrE Oant_2642 Oant_2642 Oant_2677 Oant_2677 Oant_2713 Oant_2713 Oant_2733 Oant_2733 Oant_2748 Oant_2748 Oant_2752 Oant_2752 hisG hisG Oant_3046 Oant_3046 Oant_3373 Oant_3373 Oant_3374 Oant_3374 Oant_3375 Oant_3375 Oant_3380 Oant_3380 Oant_3384 Oant_3384 Oant_3429 Oant_3429 Oant_3432 Oant_3432 Oant_3439 Oant_3439 Oant_3446 Oant_3446 Oant_3794 Oant_3794 Oant_4195 Oant_4195 Oant_4239 Oant_4239 Oant_4240 Oant_4240 Oant_4415 Oant_4415
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (375 aa)
Oant_0077PFAM: Lytic transglycosylase catalytic; KEGG: bmb:BruAb1_0067 transglycosylase SLT domain protein. (280 aa)
pncBNicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (434 aa)
Oant_0131TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: bms:BR0117 penicillin-binding protein, 1A family. (770 aa)
Oant_0243TIGRFAM: phage portal protein, HK97 family; PFAM: phage portal protein; KEGG: ecs:ECs1544 putative portal protein. (441 aa)
Oant_0307PFAM: amidohydrolase 2; KEGG: bme:BMEI1718 purine/pyrimidine phosphoribosyl transferase. (282 aa)
Oant_0391PFAM: glycosyl transferase group 1; KEGG: mes:Meso_2877 glycosyl transferase, group 1. (414 aa)
Oant_0392PFAM: glycosyl transferase group 1; Protein of unknown function DUF1972; KEGG: mes:Meso_2878 glycosyl transferase, group 1. (375 aa)
Oant_0415PFAM: glycosyl transferase family 25; KEGG: bms:BR0321 glycosyl transferase, family 25. (255 aa)
Oant_0416KEGG: mes:Meso_2115 hypothetical protein. (233 aa)
Oant_0417KEGG: bmb:BruAb1_0348 hypothetical protein. (204 aa)
Oant_0431TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; KEGG: ret:RHE_PE00439 nicotinate-nucleotide pyrophosphorylase (carboxylating) protein; Belongs to the NadC/ModD family. (285 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (496 aa)
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (403 aa)
Oant_0674KEGG: sme:SMa1321 virB1 type IV secretion protein. (229 aa)
Oant_0698PFAM: glycosyl transferase family 4; KEGG: bms:BR0511 glycosyl transferase, group 4 family protein. (335 aa)
rlpARare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (118 aa)
hisFImidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (261 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (216 aa)
Oant_0842PFAM: protein of unknown function DUF1402; KEGG: bms:BR2078 hypothetical protein. (326 aa)
Oant_0995TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: bmb:BruAb1_1961 Hpt, hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (178 aa)
Oant_1028KEGG: bms:BR1878 competence protein F, putative. (262 aa)
mtgAMonofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (244 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (208 aa)
Oant_1492Hypothetical protein. (293 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (181 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (310 aa)
Oant_1637PFAM: protein of unknown function DUF152; KEGG: bms:BR1530 conserved hypothetical protein TIGR00726; Belongs to the multicopper oxidase YfiH/RL5 family. (265 aa)
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (281 aa)
Oant_1661PFAM: glycosyl transferase group 1; KEGG: bmb:BruAb1_1496 LpcC, lipopolysaccharide core biosynthesis mannosyltransferase. (340 aa)
Oant_1715PFAM: lipid A biosynthesis domain protein; KEGG: mlo:mlr0010 hypothetical protein. (109 aa)
Oant_1716PFAM: glycosyl transferase family 2; KEGG: mlo:mlr0009 hypothetical protein. (243 aa)
Oant_1733PFAM: Lytic transglycosylase catalytic; KEGG: bms:BR1443 transglycosylase SLT domain protein. (219 aa)
Oant_1743TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: bmb:BruAb1_1427 FtsW, cell division protein; Belongs to the SEDS family. (386 aa)
Oant_1869PFAM: glycosyl transferase family 39; KEGG: jan:Jann_0917 hypothetical protein. (498 aa)
Oant_2041lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (394 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (339 aa)
rlpA-2Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (424 aa)
Oant_2105PFAM: glycosyl transferase group 1; KEGG: rpc:RPC_1446 glycosyl transferase, group 1. (353 aa)
gptXanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (165 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (383 aa)
queAQueuosine biosynthesis protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (363 aa)
Oant_2266TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: bms:BR0916 penicillin-binding protein 1A, putative. (819 aa)
cobTNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (339 aa)
Oant_2452KEGG: sit:TM1040_0076 lipopolysaccharide biosynthesis protein-like. (418 aa)
Oant_2507PFAM: glycosyl transferase group 1; KEGG: mlo:mll8436 putative transferase. (387 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (192 aa)
Oant_2642PFAM: Lytic transglycosylase catalytic; KEGG: bmb:BruAb1_0661 transglycosylase SLT domain protein. (712 aa)
Oant_2677TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: bmb:BruAb1_0604 penicillin-binding protein. (724 aa)
Oant_2713Alpha,alpha-trehalose-phosphate synthase (UDP-forming); Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family. (459 aa)
Oant_2733KEGG: cch:Cag_1481 glycosyltransferase-like. (329 aa)
Oant_2748PFAM: phosphoribulokinase/uridine kinase; KEGG: pmc:P9515_14051 hypothetical protein. (716 aa)
Oant_2752PFAM: glycosyl transferase family 2; KEGG: pmc:P9515_14031 hypothetical protein. (242 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (231 aa)
Oant_3046Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (446 aa)
Oant_3373PFAM: glycosyl transferase group 1; KEGG: bme:BMEII0847 glycosyl transferase. (423 aa)
Oant_3374PFAM: glycosyl transferase group 1; KEGG: bms:BRA0421 glycosyl transferase, group 1 family protein. (408 aa)
Oant_3375PFAM: glycosyl transferase group 1; KEGG: bms:BRA0422 glycosyl transferase, group 1 family protein. (399 aa)
Oant_3380PFAM: glycosyl transferase family 4; KEGG: bms:BRA0428 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase, putative. (382 aa)
Oant_3384PFAM: glycosyl transferase group 1; KEGG: bms:BRA0432 glycosyl transferase, group 1 family protein. (410 aa)
Oant_3429PFAM: glycosyl transferase group 1; KEGG: sme:SMb21308 putative glycosyltransferase, forming alpha glycosyl linkages protein. (440 aa)
Oant_3432PFAM: glycosyl transferase group 1; KEGG: sme:SMb21311 putative glycosyltransferase, forming alpha-gylcosyl linkages protein. (419 aa)
Oant_3439PFAM: glycosyl transferase group 1; KEGG: sme:SMb21318 putative glycosyltransferase, forming alpha-glycosyl linkages protein. (406 aa)
Oant_3446TIGRFAM: penicillin-binding protein 1C; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; Penicillin-binding domain protein; KEGG: mlo:mlr1664 penicillin binding protein. (695 aa)
Oant_3794Regulatory protein LysR; PFAM: glycosyl transferase family 3; regulatory protein LysR; KEGG: atc:AGR_L_1856 hypothetical protein. (491 aa)
Oant_4195PFAM: Lytic transglycosylase catalytic; KEGG: bmb:BruAb2_1078 hypothetical protein. (180 aa)
Oant_4239KEGG: bmb:BruAb2_0104 hypothetical protein. (400 aa)
Oant_4240TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF; KEGG: bms:BRA0104 glycosyl transferase, WecB/TagA/CpsF family; Belongs to the glycosyltransferase 26 family. (252 aa)
Oant_4415KEGG: bmb:BruAb2_0678 glycosyl transferase, group 2 family protein. (616 aa)
Your Current Organism:
Ochrobactrum anthropi
NCBI taxonomy Id: 439375
Other names: O. anthropi ATCC 49188, Ochrobactrum anthropi ATCC 49188, Ochrobactrum anthropi DSM 6882, Ochrobactrum anthropi LMG 3331, Ochrobactrum anthropi str. ATCC 49188, Ochrobactrum anthropi strain ATCC 49188
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