STRINGSTRING
Oant_0989 Oant_0989 ftsE ftsE Oant_0985 Oant_0985 Oant_2339 Oant_2339 Oant_1022 Oant_1022 Oant_1061 Oant_1061 Oant_1192 Oant_1192 tolQ tolQ tolB tolB pal pal cpoB cpoB engB engB Oant_1737 Oant_1737 Oant_1738 Oant_1738 murE murE murF murF mraY mraY murD murD Oant_1743 Oant_1743 murG murG murC murC murB murB ftsQ ftsQ ftsA ftsA ftsZ ftsZ Oant_2050 Oant_2050 Oant_2058 Oant_2058 Oant_2211 Oant_2211 tig tig Oant_4322 Oant_4322 Oant_4044 Oant_4044 Oant_3955 Oant_3955 pdhS pdhS Oant_3557 Oant_3557 murA-2 murA-2 minE minE Oant_2971 Oant_2971 minC minC Oant_2895 Oant_2895 Oant_2350 Oant_2350 Oant_2346 Oant_2346 murA murA Oant_0520 Oant_0520 Oant_0548 Oant_0548 Oant_0698 Oant_0698 Oant_0814 Oant_0814 xerD xerD ftsY ftsY xerC xerC Oant_0960 Oant_0960
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Oant_0989PFAM: protein of unknown function YGGT; KEGG: bmb:BruAb1_1967 YGGT family protein. (114 aa)
ftsECell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (236 aa)
Oant_0985PFAM: protein of unknown function DUF214; KEGG: bms:BR1996 membrane protein, putative. (347 aa)
Oant_2339Peptidase M23B; PFAM: Peptidoglycan-binding LysM; peptidase M23B; KEGG: bmb:BruAb1_0900 peptidase, M23/M37 family. (438 aa)
Oant_1022PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: bms:BR1943 peptidyl-prolyl cis-trans isomerase. (326 aa)
Oant_1061PFAM: peptidase M23B; KEGG: bmb:BruAb1_1817 hypothetical protein. (440 aa)
Oant_1192PFAM: protein of unknown function DUF710; KEGG: bmb:BruAb1_1709 hypothetical protein. (107 aa)
tolQTol-Pal system TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (236 aa)
tolBTol-Pal system beta propeller repeat TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (443 aa)
palPeptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (168 aa)
cpoBTol-Pal system YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (505 aa)
engBGTP-binding protein HSR1-related; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (241 aa)
Oant_1737KEGG: bms:BR1438 hypothetical protein. (133 aa)
Oant_1738Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: bmb:BruAb1_1432 penicillin-binding protein. (594 aa)
murEUDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (490 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (476 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (360 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (467 aa)
Oant_1743TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: bmb:BruAb1_1427 FtsW, cell division protein; Belongs to the SEDS family. (386 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (375 aa)
murCUDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (468 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (320 aa)
ftsQPolypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. (295 aa)
ftsACell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (440 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (565 aa)
Oant_2050KEGG: bms:BR1139 rotamase family protein. (628 aa)
Oant_2058PFAM: Septum formation initiator; KEGG: bmb:BruAb1_1136 hypothetical protein. (109 aa)
Oant_2211Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PAS fold domain protein; KEGG: bmb:BruAb1_1122 NtrY, nitrogen regulation protein NtrY. (771 aa)
tigTrigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (485 aa)
Oant_4322PFAM: phage integrase family protein; KEGG: mag:amb1630 hypothetical protein. (193 aa)
Oant_4044PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: mlo:mll5481 probable DNA ligase. (539 aa)
Oant_3955PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bmb:BruAb2_0455 3-ketoacyl-(acyl-carrier-protein) reductase. (249 aa)
pdhSPAS/PAC sensor signal transduction histidine kinase; Functions as a polar differentiation marker. Essential protein that, by localizing in the old pole of dividing cells, controls cell division and maturation, probably through control of DivK phosphorylation status and cellular distribution, which in turn regulates CtrA, a transcriptional regulator of the minB operon. The asymmetrical localization of this protein is probably required for cells to enter a new division cycle (By similarity). (1055 aa)
Oant_3557PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: bms:BRA0530 cell division protein FtsK, putative; Belongs to the FtsK/SpoIIIE/SftA family. (830 aa)
murA-2UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (418 aa)
minECell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. (89 aa)
Oant_2971TIGRFAM: septum site-determining protein MinD; PFAM: Cobyrinic acid ac-diamide synthase; KEGG: bms:BRA0322 septum site-determining protein MinD. (271 aa)
minCSeptum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (242 aa)
Oant_2895PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: bms:BRA0295 peptidyl-prolyl cis-trans isomerase, putative. (308 aa)
Oant_2350PFAM: Sporulation domain protein; KEGG: bmb:BruAb1_0890 hypothetical protein. (993 aa)
Oant_2346Putative transcriptional regulator; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (242 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (429 aa)
Oant_0520PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: bmb:BruAb1_0425 TPR domain protein. (621 aa)
Oant_0548TIGRFAM: hemolysin A; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; RNA-binding S4 domain protein; KEGG: bmb:BruAb1_0459 TlyA, hemolysin A. (253 aa)
Oant_0698PFAM: glycosyl transferase family 4; KEGG: bms:BR0511 glycosyl transferase, group 4 family protein. (335 aa)
Oant_0814TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain protein; KEGG: bmb:BruAb1_2081 FolC, FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. (430 aa)
xerDTyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (307 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (494 aa)
xerCTyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (315 aa)
Oant_0960PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: bms:BR1895 cell division protein FtsK, putative. (858 aa)
Your Current Organism:
Ochrobactrum anthropi
NCBI taxonomy Id: 439375
Other names: O. anthropi ATCC 49188, Ochrobactrum anthropi ATCC 49188, Ochrobactrum anthropi DSM 6882, Ochrobactrum anthropi LMG 3331, Ochrobactrum anthropi str. ATCC 49188, Ochrobactrum anthropi strain ATCC 49188
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