STRINGSTRING
Oant_2633 Oant_2633 rlmN rlmN Oant_0105 Oant_0105 nth nth Oant_0185 Oant_0185 Oant_0190 Oant_0190 nadA nadA Oant_0508 Oant_0508 ispH ispH Oant_0607 Oant_0607 miaB miaB Oant_0926 Oant_0926 leuC leuC Oant_0954 Oant_0954 queE queE ispG ispG Oant_1133 Oant_1133 queG queG Oant_1449 Oant_1449 Oant_1899 Oant_1899 Oant_2016 Oant_2016 lipA lipA Oant_2193 Oant_2193 Oant_2225 Oant_2225 moaA moaA Oant_2255 Oant_2255 Oant_2358 Oant_2358 ttcA ttcA nuoI nuoI Oant_2417 Oant_2417 Oant_2418 Oant_2418 nuoB nuoB Oant_2579 Oant_2579 Oant_2639 Oant_2639 Oant_2658 Oant_2658 Oant_2659 Oant_2659 bioB bioB Oant_2862 Oant_2862 Oant_2863 Oant_2863 Oant_2891 Oant_2891 Oant_3012 Oant_3012 Oant_3115 Oant_3115 Oant_3116 Oant_3116 rimO rimO edd edd Oant_4013 Oant_4013 Oant_4300 Oant_4300 Oant_4436 Oant_4436
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Oant_2633KEGG: bms:BR0655 oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (444 aa)
rlmNRadical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (411 aa)
Oant_0105Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (895 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (249 aa)
Oant_0185Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (409 aa)
Oant_0190PFAM: nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; KEGG: bms:BR0181 sulfite reductase (NADPH) hemoprotein beta-component. (556 aa)
nadAQuinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (323 aa)
Oant_0508PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: bms:BR0387 hypothetical protein. (390 aa)
ispHHydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (350 aa)
Oant_0607A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (364 aa)
miaBRNA modification enzyme, MiaB family; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (462 aa)
Oant_0926MiaB-like tRNA modifying enzyme; KEGG: bmb:BruAb1_1909 hypothetical protein; TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme; PFAM: Radical SAM domain protein; Protein of unknown function UPF0004; SMART: Elongator protein 3/MiaB/NifB. (427 aa)
leuC3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (469 aa)
Oant_0954TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: bmb:BruAb1_1877 SdhB, succinate dehydrogenase, iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (259 aa)
queERadical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (246 aa)
ispG1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (423 aa)
Oant_11334Fe-4S ferredoxin iron-sulfur binding domain protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (112 aa)
queGDomain of unknown function DUF1730; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (393 aa)
Oant_1449TIGRFAM: oxidoreductase alpha (molybdopterin) subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: bmb:BruAb2_0314 oxidoreductase, molybdopterin-binding, hypothetical; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (770 aa)
Oant_1899TIGRFAM: precorrin-3B synthase; PFAM: nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; KEGG: bms:BR1286 nitrite reductase family protein. (439 aa)
Oant_2016TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; KEGG: bms:BR1175 L-serine dehydratase, iron-sulfur-dependent, single chain form. (467 aa)
lipALipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (321 aa)
Oant_2193Phosphonate metabolism PhnJ; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family. (297 aa)
Oant_2225Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (539 aa)
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (345 aa)
Oant_2255TIGRFAM: FeS assembly protein SufB; PFAM: SufBD protein; KEGG: bmb:BruAb1_0940 hypothetical protein. (507 aa)
Oant_2358KEGG: bmb:BruAb1_0881 hypothetical protein. (210 aa)
ttcAPP-loop domain protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (292 aa)
nuoINADH-quinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (163 aa)
Oant_2417NADH-quinone oxidoreductase, chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (694 aa)
Oant_2418NADH-quinone oxidoreductase, F subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (435 aa)
nuoBNADH-quinone oxidoreductase, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity). (193 aa)
Oant_2579PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: bmb:BruAb1_0726 oxidoreductase, molybdopterin-binding, hypothetical; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (706 aa)
Oant_2639PFAM: Uracil-DNA glycosylase superfamily; KEGG: bmb:BruAb1_0665 SPO1 DNA polymerase-related protein. (216 aa)
Oant_2658Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone. (568 aa)
Oant_2659TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily; KEGG: bmb:BruAb1_0639 phage SPO1 DNA polymerase-related protein. (285 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (336 aa)
Oant_2862PFAM: molybdopterin oxidoreductase Fe4S4 region; KEGG: sme:SMa0002 probable FdoG formate dehydrogenase-O alpha subunit. (199 aa)
Oant_2863TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: sme:SMa0002 probable FdoG formate dehydrogenase-O alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (824 aa)
Oant_2891TIGRFAM: nitrate reductase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: bms:BRA0299 respiratory nitrate reductase, alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1254 aa)
Oant_3012PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: bms:BRA0182 glycolate oxidase, iron-sulfur subunit. (435 aa)
Oant_3115PFAM: peptidase U32; KEGG: bmb:BruAb2_0892 hypothetical protease. (306 aa)
Oant_3116PFAM: peptidase U32; KEGG: bmb:BruAb2_0891 peptidase, U32 family. (325 aa)
rimOMiaB-like tRNA modifying enzyme YliG; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (437 aa)
edd6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (607 aa)
Oant_4013Indolepyruvate ferredoxin oxidoreductase; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: bja:bll3411 indolepyruvate ferredoxin oxidoreductase alpha subunit. (717 aa)
Oant_4300TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily; KEGG: mes:Meso_2840 phage SPO1 DNA polymerase-related protein. (207 aa)
Oant_4436KEGG: pol:Bpro_3944 hypothetical protein. (102 aa)
Your Current Organism:
Ochrobactrum anthropi
NCBI taxonomy Id: 439375
Other names: O. anthropi ATCC 49188, Ochrobactrum anthropi ATCC 49188, Ochrobactrum anthropi DSM 6882, Ochrobactrum anthropi LMG 3331, Ochrobactrum anthropi str. ATCC 49188, Ochrobactrum anthropi strain ATCC 49188
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