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| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (241 aa) |
| | kdsB | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (249 aa) |
| | Oant_0036 | TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; KEGG: bms:BR0021 acetoacetyl-CoA synthase. (662 aa) |
| | Oant_0055 | PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: bmb:BruAb1_0050 lipoprotein, hypothetical. (241 aa) |
| | Oant_0077 | PFAM: Lytic transglycosylase catalytic; KEGG: bmb:BruAb1_0067 transglycosylase SLT domain protein. (280 aa) |
| | Oant_0119 | PFAM: protein of unknown function DUF218; KEGG: bme:BMEI1842 hypothetical protein. (277 aa) |
| | Oant_0131 | TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: bms:BR0117 penicillin-binding protein, 1A family. (770 aa) |
| | Oant_0143 | PFAM: GCN5-related N-acetyltransferase; KEGG: bms:BR0129 acetyltransferase, GNAT family. (157 aa) |
| | Oant_0152 | PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: bmb:BruAb1_0136 lipoprotein, hypothetical. (206 aa) |
| | murJ | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (529 aa) |
| | Oant_0164 | KEGG: bmb:BruAb1_0148 hypothetical protein. (107 aa) |
| | Oant_0261 | KEGG: mes:Meso_0243 hypothetical protein. (239 aa) |
| | Oant_0269 | PFAM: FAD dependent oxidoreductase; KEGG: bms:BR0200 glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (503 aa) |
| | Oant_0275 | PFAM: sulfatase; KEGG: mlo:mll7848 putative cyclic beta-1,2-glucan modification protein. (636 aa) |
| | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (429 aa) |
| | pgi | PFAM: phosphoglucose isomerase (PGI); KEGG: bms:BR0285 glucose-6-phosphate isomerase; Belongs to the GPI family. (549 aa) |
| | Oant_0379 | PFAM: glycosyl transferase family 2; KEGG: bmb:BruAb1_0322 glycosyl transferase, group 2 family protein. (626 aa) |
| | Oant_0382 | KEGG: rpd:RPD_3294 protein involved in cellulose biosynthesis (CelD)-like. (375 aa) |
| | Oant_0386 | PFAM: polysaccharide biosynthesis protein; KEGG: sme:SMb21513 putative cell-surface polysaccharide exporter protein, PST family. (427 aa) |
| | Oant_0388 | PFAM: O-antigen polymerase; KEGG: sme:SMb21505 putative membrane protein, similar to Wzy-like polysaccharide polymerase ExoQ. (358 aa) |
| | Oant_0399 | PFAM: 2-deoxycytidine 5-triphosphate deaminase; KEGG: bmb:BruAb1_0332 dCTP deaminase. (363 aa) |
| | pyrD | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (364 aa) |
| | Oant_0415 | PFAM: glycosyl transferase family 25; KEGG: bms:BR0321 glycosyl transferase, family 25. (255 aa) |
| | Oant_0416 | KEGG: mes:Meso_2115 hypothetical protein. (233 aa) |
| | Oant_0417 | KEGG: bmb:BruAb1_0348 hypothetical protein. (204 aa) |
| | Oant_0424 | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mlo:mll3759 similar to ABC transporter (binding protein). (317 aa) |
| | Oant_0473 | PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: rsp:RSP_1873 hypothetical protein. (264 aa) |
| | atpB1 | ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (249 aa) |
| | atpE | H+transporting two-sector ATPase C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (75 aa) |
| | atpF1 | H+transporting two-sector ATPase B/B' subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (205 aa) |
| | atpF2 | ATP synthase F0, B subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (159 aa) |
| | ispE | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (289 aa) |
| | Oant_0516 | KEGG: ret:RHE_PE00140 hypothetical protein. (113 aa) |
| | purD | TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; KEGG: bmb:BruAb1_0437 PurD, phosphoribosylamine--glycine ligase; Belongs to the GARS family. (429 aa) |
| | Oant_0536 | PFAM: Phosphoglycerate mutase; KEGG: bme:BMEI1511 phosphoglycerate mutase/fructose-2,6-bisphosphatase. (196 aa) |
| | dxs | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (638 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (496 aa) |
| | Oant_0564 | PFAM: purine nucleoside permease; KEGG: pat:Patl_1764 putative purine nucleoside permease protein. (337 aa) |
| | mltG | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (403 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (220 aa) |
| | ispH | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (350 aa) |
| | Oant_0595 | PFAM: protein of unknown function DUF179; KEGG: bme:BMEI1454 transcriptional regulator, AlgH; Belongs to the UPF0301 (AlgH) family. (214 aa) |
| | Oant_0608 | PFAM: glycosyl transferase family 25; KEGG: mes:Meso_1375 glycosyl transferase, family 25. (255 aa) |
| | Oant_0609 | PFAM: O-antigen polymerase; KEGG: mes:Meso_1374 O-antigen polymerase. (419 aa) |
| | Oant_0610 | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: rfr:Rfer_0656 NAD-dependent epimerase/dehydratase. (325 aa) |
| | Oant_0624 | Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: pen:PSEEN3285 transcriptional regulator, RipR family. (297 aa) |
| | Oant_0661 | Transketolase central region; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (790 aa) |
| | Oant_0674 | KEGG: sme:SMa1321 virB1 type IV secretion protein. (229 aa) |
| | Oant_0697 | Polysaccharide biosynthesis protein CapD; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: bms:BR0510 epimerase/dehydratase, putative. (622 aa) |
| | Oant_0698 | PFAM: glycosyl transferase family 4; KEGG: bms:BR0511 glycosyl transferase, group 4 family protein. (335 aa) |
| | rlpA | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (118 aa) |
| | Oant_0808 | PFAM: protein of unknown function DUF218; KEGG: bme:BMEI2016 hypothetical protein. (212 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (301 aa) |
| | Oant_0814 | TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain protein; KEGG: bmb:BruAb1_2081 FolC, FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. (430 aa) |
| | Oant_0823 | PFAM: Asp/Glu racemase; KEGG: dra:DR1586 glutamate racemase. (278 aa) |
| | coaA | TIGRFAM: pantothenate kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: bms:BR2087 pantothenate kinase. (322 aa) |
| | Oant_0842 | PFAM: protein of unknown function DUF1402; KEGG: bms:BR2078 hypothetical protein. (326 aa) |
| | Oant_0845 | PFAM: MltA domain protein; 3D domain protein; KEGG: bmb:BruAb1_2050 transglycosylase-related protein. (365 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (222 aa) |
| | Oant_0902 | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: bmb:BruAb1_2011 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (371 aa) |
| | Oant_0905 | PFAM: protein of unknown function DUF949; KEGG: bms:BR2033 lipoprotein, putative. (412 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa) |
| | Oant_0917 | Conserved hypothetical integral membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (216 aa) |
| | sucA | 2-oxoglutarate dehydrogenase, E1 subunit; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). (1001 aa) |
| | Oant_0934 | 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (409 aa) |
| | Oant_0958 | TIGRFAM: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase; KEGG: bme:BMEI0166 acyl-CoA thioesterase II. (300 aa) |
| | Oant_0966 | KEGG: bme:BMEI0065 hypothetical cytosolic protein. (181 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase (NAD(P)(+)); PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Ketopantoate reductase ApbA/PanE domain protein; KEGG: bmb:BruAb1_1866 GpsA, glycerol-3-phosphate dehydrogenase, NAD-dependent. (329 aa) |
| | Oant_0986 | PFAM: protein of unknown function DUF218; KEGG: bme:BMEI0074 hypothetical protein. (302 aa) |
| | Oant_0995 | TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: bmb:BruAb1_1961 Hpt, hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (178 aa) |
| | queE | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (246 aa) |
| | Oant_1009 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: bmb:BruAb1_1949 hypothetical 6-pyruvoyl tetrahydrobiopterin synthase. (118 aa) |
| | queC | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (232 aa) |
| | Oant_1018 | PFAM: sulfatase; protein of unknown function DUF1705; KEGG: bms:BR1948 membrane protein, putative. (544 aa) |
| | Oant_1019 | KEGG: bmb:BruAb1_1923 hypothetical protein. (428 aa) |
| | Oant_1040 | PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: bms:BR1862 hypothetical protein. (488 aa) |
| | rppH | NUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. (174 aa) |
| | glpK | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (499 aa) |
| | purH | TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; KEGG: bms:BR1816 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (538 aa) |
| | Oant_1088 | PFAM: Heparinase II/III family protein; KEGG: bmb:BruAb1_1795 hypothetical protein. (580 aa) |
| | acsA | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa) |
| | tal | Putative transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa) |
| | atpH | ATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (186 aa) |
| | atpA | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (509 aa) |
| | atpG | ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (292 aa) |
| | atpD | ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (517 aa) |
| | atpC | ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (135 aa) |
| | ispG | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (423 aa) |
| | mtgA | Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (244 aa) |
| | Oant_1165 | TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; KEGG: bms:BR1748 pyruvate kinase; Belongs to the pyruvate kinase family. (478 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (366 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (164 aa) |
| | Oant_1183 | PFAM: AMP-dependent synthetase and ligase; KEGG: bmf:BAB1_1744 AMP-dependent synthetase and ligase. (636 aa) |
| | Oant_1185 | PFAM: fructose-bisphosphate aldolase class-I; KEGG: mes:Meso_3436 fructose-bisphosphate aldolase, class-I. (341 aa) |
| | pgk | PFAM: phosphoglycerate kinase; KEGG: bme:BMEI0309 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (401 aa) |
| | Oant_1190 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (663 aa) |
| | purA | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (429 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (170 aa) |
| | Oant_1283 | PFAM: Ankyrin; KEGG: bur:Bcep18194_B0071 ankyrin repeat protein. (214 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (208 aa) |
| | Oant_1319 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (461 aa) |
| | gpmA | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (206 aa) |
| | glk | TIGRFAM: glucokinase; PFAM: Glucokinase; KEGG: bms:BRA1049 glucokinase; Belongs to the bacterial glucokinase family. (346 aa) |
| | Oant_1336 | PFAM: NAD-dependent epimerase/dehydratase; KEGG: bmb:BruAb2_0986 hypothetical protein. (289 aa) |
| | queG | Domain of unknown function DUF1730; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (393 aa) |
| | uppP | Putative undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (268 aa) |
| | Oant_1407 | Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: rle:pRL120428 putative DNA-binding protein. (280 aa) |
| | Oant_1455 | Glutamine--fructose-6-phosphate transaminase (isomerizing); PFAM: sugar isomerase (SIS); KEGG: bmb:BruAb2_0321 NagB, glucosamine-fructose-6-phosphate aminotransferase. (343 aa) |
| | Oant_1456 | TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; KEGG: bmb:BruAb2_0322 NagA, N-acetylglucosamine-6-phosphate deacetylase. (388 aa) |
| | Oant_1457 | KEGG: bms:BRA0910 hypothetical protein; Belongs to the UPF0309 family. (242 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (294 aa) |
| | Oant_1484 | KEGG: sme:SMb20922 hypothetical protein. (323 aa) |
| | Oant_1529 | TIGRFAM: deoxycytidine triphosphate deaminase; PFAM: deoxyUTP pyrophosphatase; KEGG: mhu:Mhun_2260 deoxycytidine triphosphate deaminase. (152 aa) |
| | Oant_1565 | PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aminotransferase class-III; KEGG: bmb:BruAb1_1588 DegT/DnrJ/EryC1/StrS family protein; Belongs to the DegT/DnrJ/EryC1 family. (374 aa) |
| | Oant_1619 | PFAM: purine nucleoside permease; KEGG: bme:BMEI0469 purine nucleoside permease. (345 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (181 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (310 aa) |
| | Oant_1655 | PFAM: thioesterase superfamily protein; KEGG: bmb:BruAb1_1502 long-chain acyl-CoA thioester hydrolase, hypothetical. (129 aa) |
| | carB | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; RimK domain protein ATP-grasp; KEGG: bms:BR1488 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. (1161 aa) |
| | carA | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: bms:BR1483 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (407 aa) |
| | Oant_1714 | PFAM: UDP-glucose/GDP-mannose dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: atc:AGR_L_1413 UDPglucose 6-dehydrogenase. (436 aa) |
| | Oant_1715 | PFAM: lipid A biosynthesis domain protein; KEGG: mlo:mlr0010 hypothetical protein. (109 aa) |
| | Oant_1726 | PFAM: glycoside hydrolase family 25; KEGG: bms:BR1447 glycosyl hydrolase, family 25. (277 aa) |
| | Oant_1732 | PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: bmb:BruAb1_1439 N-acetylmuramoyl-L-alanine amidase, family 2. (268 aa) |
| | Oant_1733 | PFAM: Lytic transglycosylase catalytic; KEGG: bms:BR1443 transglycosylase SLT domain protein. (219 aa) |
| | murE | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (490 aa) |
| | murF | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (476 aa) |
| | mraY | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (360 aa) |
| | murD | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (467 aa) |
| | Oant_1743 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: bmb:BruAb1_1427 FtsW, cell division protein; Belongs to the SEDS family. (386 aa) |
| | murG | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (375 aa) |
| | murC | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (468 aa) |
| | murB | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (320 aa) |
| | ddl | D-alanine--D-alanine ligase; Cell wall formation. (308 aa) |
| | lpxC | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (312 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa) |
| | Oant_1869 | PFAM: glycosyl transferase family 39; KEGG: jan:Jann_0917 hypothetical protein. (498 aa) |
| | Oant_1914 | Peptidase M15A; PFAM: protein of unknown function DUF882; Peptidase M15A; KEGG: bmb:BruAb1_1278 hypothetical protein. (421 aa) |
| | Oant_1938 | PFAM: CBS domain containing protein; KEGG: bmb:BruAb1_1258 CBS domain protein. (143 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (194 aa) |
| | murI | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (278 aa) |
| | queF | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (155 aa) |
| | Oant_2010 | KEGG: bms:BR1181 hypothetical protein. (105 aa) |
| | Oant_2014 | PFAM: protein of unknown function DUF218; KEGG: bmb:BruAb1_1183 hypothetical protein. (235 aa) |
| | Oant_2019 | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Sporulation domain protein; KEGG: bmb:BruAb1_1178 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (469 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (240 aa) |
| | lpxD | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (352 aa) |
| | fabZ | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (157 aa) |
| | lpxA | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (278 aa) |
| | Oant_2040 | PFAM: protein of unknown function DUF1009; KEGG: bmb:BruAb1_1156 conserved hypothetical protein TIGR00148. (299 aa) |
| | Oant_2041 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (394 aa) |
| | tpiA | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (254 aa) |
| | Oant_2053 | PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: bmb:BruAb1_1142 hypothetical protein. (230 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (542 aa) |
| | kdsA | TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: bme:BMEI0850 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase). (277 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa) |
| | pdhA | Dehydrogenase E1 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (346 aa) |
| | Oant_2060 | Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (465 aa) |
| | Oant_2061 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (444 aa) |
| | ispDF | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. (407 aa) |
| | rlpA-2 | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (424 aa) |
| | Oant_2076 | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: bms:BR0991 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (398 aa) |
| | tmk | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (218 aa) |
| | rpiA | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (232 aa) |
| | Oant_2104 | PFAM: metallophosphoesterase; KEGG: mlo:mll0806 hypothetical protein. (288 aa) |
| | gpt | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (165 aa) |
| | Oant_2146 | PFAM: acetyl-CoA hydrolase/transferase; KEGG: bmb:BruAb1_1062 acetyl-CoA hydrolase/transferase family protein. (504 aa) |
| | Oant_2150 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: bms:BR1067 mazG family protein. (274 aa) |
| | Oant_2155 | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Sporulation domain protein; KEGG: bmb:BruAb1_1077 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (404 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (383 aa) |
| | queA | Queuosine biosynthesis protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (363 aa) |
| | coaD | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (164 aa) |
| | phnN | Phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). (194 aa) |
| | Oant_2215 | KEGG: mac:MA1909 dTDP-4-dehydrorhamnose 3,5-epimerase. (181 aa) |
| | Oant_2224 | PFAM: Peptidoglycan-binding domain 1 protein; KEGG: bms:BR0962 hypothetical protein. (668 aa) |
| | Oant_2266 | TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: bms:BR0916 penicillin-binding protein 1A, putative. (819 aa) |
| | Oant_2267 | N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; KEGG: bms:BR0915 N-acetylmuramoyl-L-alanine amidase, family 3. (421 aa) |
| | Oant_2274 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (459 aa) |
| | Oant_2287 | PFAM: glycoside hydrolase family 24; KEGG: sit:TM1040_1305 glycoside hydrolase, family 24. (168 aa) |
| | surE | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (258 aa) |
| | Oant_2352 | TIGRFAM: putative deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: bmb:BruAb1_0888 Dgt, deoxyguanosinetriphosphate triphosphohydrolase; Belongs to the dGTPase family. Type 2 subfamily. (402 aa) |
| | Oant_2371 | PFAM: phosphopantetheine-binding; KEGG: bmb:BruAb1_0867 acyl carrier protein. (93 aa) |
| | Oant_2375 | PFAM: lipid A biosynthesis acyltransferase; KEGG: bmb:BruAb1_0863 lipid A biosynthesis lauroyl acyltransferase, hypothetical. (308 aa) |
| | Oant_2376 | PFAM: ribulose-phosphate 3-epimerase; Orotidine 5'-phosphate decarboxylase; KEGG: bms:BR0850 ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (225 aa) |
| | Oant_2377 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: bms:BR0849 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (433 aa) |
| | purC | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; KEGG: bms:BR0842 phosphoribosylaminoimidazole-succinocarboxamide synthase. (254 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (80 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (223 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (740 aa) |
| | Oant_2460 | PFAM: carbohydrate kinase FGGY; KEGG: rme:Rmet_5445 carbohydrate kinase, FGGY; Belongs to the FGGY kinase family. (507 aa) |
| | Oant_2461 | PFAM: FAD dependent oxidoreductase; KEGG: rme:Rmet_5444 FAD dependent oxidoreductase. (559 aa) |
| | Oant_2487 | PFAM: LmbE family protein; KEGG: atc:AGR_L_453 hypothetical protein. (797 aa) |
| | Oant_2504 | KEGG: mlo:mll8447 hypothetical protein. (373 aa) |
| | Oant_2505 | TIGRFAM: exopolysaccharide transport protein family; PFAM: lipopolysaccharide biosynthesis protein; KEGG: mlo:mlr8439 succinoglycan transport protein ExoP. (735 aa) |
| | Oant_2510 | KEGG: mlo:mll8434 hypothetical protein. (424 aa) |
| | atpB2 | ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (249 aa) |
| | Oant_2531 | PFAM: Peptidoglycan-binding domain 1 protein; KEGG: bmb:BruAb1_0779 peptidoglycan-binding protein, hypothetical. (433 aa) |
| | Oant_2552 | PFAM: GCN5-related N-acetyltransferase; KEGG: ava:Ava_1487 GCN5-related N-acetyltransferase. (135 aa) |
| | Oant_2553 | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: atc:AGR_C_4132 hypothetical protein. (124 aa) |
| | Oant_2573 | PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: bms:BR0715 epimerase/dehydratase family protein, putative. (287 aa) |
| | purM | TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: bmb:BruAb1_0729 PurM, phosphoribosylformylglycinamidine cyclo-ligase. (363 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (205 aa) |
| | ndk | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa) |
| | Oant_2623 | KEGG: bmb:BruAb1_0683 hypothetical protein. (206 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (192 aa) |
| | Oant_2636 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (748 aa) |
| | Oant_2642 | PFAM: Lytic transglycosylase catalytic; KEGG: bmb:BruAb1_0661 transglycosylase SLT domain protein. (712 aa) |
| | amn | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (500 aa) |
| | Oant_2677 | TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: bmb:BruAb1_0604 penicillin-binding protein. (724 aa) |
| | Oant_2699 | PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: bmb:BruAb1_0586 hypothetical protein. (238 aa) |
| | Oant_2718 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (292 aa) |
| | Oant_2719 | TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: mlo:mlr7552 dTDP-D-glucose-4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (358 aa) |
| | Oant_2720 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (183 aa) |
| | Oant_2733 | KEGG: cch:Cag_1481 glycosyltransferase-like. (329 aa) |
| | Oant_2801 | Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; KEGG: rle:RL4211 putative transcriptional regulator. (284 aa) |
| | Oant_2837 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. (319 aa) |
| | Oant_2902 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (666 aa) |
| | Oant_2904 | Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa) |
| | Oant_2910 | PFAM: FAD dependent oxidoreductase; KEGG: bmb:BruAb2_0367 EryB, erythritol phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (502 aa) |
| | Oant_2918 | PFAM: FAD dependent oxidoreductase; KEGG: rle:pRL120197 putative glycerol-3-phosphate dehydrogenase. (566 aa) |
| | Oant_2955 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (328 aa) |
| | Oant_2966 | KEGG: bmb:BruAb2_0378 hypothetical membrane protein. (139 aa) |
| | Oant_2967 | PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: bmb:BruAb2_0379 hypothetical epimerase/dehydratase family protein. (335 aa) |
| | Oant_2981 | Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: pna:Pnap_4066 transcriptional regulator, RpiR family. (282 aa) |
| | Oant_2997 | PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: atc:AGR_L_2979 hypothetical protein. (249 aa) |
| | Oant_3014 | PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: bms:BRA0184 hypothetical protein. (255 aa) |
| | Oant_3030 | TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain; PFAM: Riboflavin kinase / FAD synthetase; KEGG: bme:BMEII1044 hypothetical protein; Belongs to the ribF family. (329 aa) |
| | Oant_3031 | PFAM: MltA-interacting MipA family protein; KEGG: mlo:mlr8248 hypothetical protein. (286 aa) |
| | Oant_3046 | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (446 aa) |
| | lpxK | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (341 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (497 aa) |
| | Oant_3057 | KEGG: bms:BRA0360 MTA/SAH nucleosidase family protein. (216 aa) |
| | guaA | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (523 aa) |
| | Oant_3077 | PFAM: FAD dependent oxidoreductase; KEGG: ret:RHE_PB00073 probable glycerol-3-phosphate dehydrogenase protein. (582 aa) |
| | Oant_3078 | PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: ret:RHE_PB00072 putative aldolase protein. (280 aa) |
| | Oant_3109 | PFAM: AMP-dependent synthetase and ligase; KEGG: bms:BRA0450 acetyl-CoA synthetase, putative. (557 aa) |
| | Oant_3122 | Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: mlo:mlr7253 hypothetical protein. (282 aa) |
| | murA-2 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (418 aa) |
| | murQ | Glucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. (307 aa) |
| | anmK | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (371 aa) |
| | Oant_3250 | PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: atc:AGR_L_2979 hypothetical protein. (256 aa) |
| | Oant_3299 | Citrate (pro-3S)-lyase; PFAM: HpcH/HpaI aldolase; KEGG: bme:BMEII0413 citrate lyase beta chain / citryl-CoA lyase subunit; Belongs to the HpcH/HpaI aldolase family. (291 aa) |
| | Oant_3301 | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: bmb:BruAb2_0353 glyoxalase family protein. (117 aa) |
| | Oant_3322 | KEGG: rpb:RPB_1036 hypothetical protein. (286 aa) |
| | Oant_3329 | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMb21202 hypothetical protein. (308 aa) |
| | Oant_3369 | PFAM: lipopolysaccharide biosynthesis protein; KEGG: bme:BMEII0852 succinoglycan biosynthesis transport protein ExoP. (731 aa) |
| | fcl | NAD-dependent epimerase/dehydratase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (326 aa) |
| | gmd | GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (371 aa) |
| | Oant_3373 | PFAM: glycosyl transferase group 1; KEGG: bme:BMEII0847 glycosyl transferase. (423 aa) |
| | Oant_3378 | PFAM: protein of unknown function DUF218; KEGG: bms:BRA0426 Bme2 protein. (206 aa) |
| | Oant_3380 | PFAM: glycosyl transferase family 4; KEGG: bms:BRA0428 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase, putative. (382 aa) |
| | Oant_3381 | PFAM: polysaccharide biosynthesis protein; virulence factor MVIN family protein; KEGG: bms:BRA0429 polysaccharide biosynthesis protein. (494 aa) |
| | Oant_3384 | PFAM: glycosyl transferase group 1; KEGG: bms:BRA0432 glycosyl transferase, group 1 family protein. (410 aa) |
| | Oant_3387 | PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: bms:BRA0435 epimerase/dehydratase family protein, putative. (353 aa) |
| | Oant_3389 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (174 aa) |
| | Oant_3405 | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; KEGG: atc:AGR_L_3333 hypothetical protein. (265 aa) |
| | Oant_3439 | PFAM: glycosyl transferase group 1; KEGG: sme:SMb21318 putative glycosyltransferase, forming alpha-glycosyl linkages protein. (406 aa) |
| | Oant_3446 | TIGRFAM: penicillin-binding protein 1C; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; Penicillin-binding domain protein; KEGG: mlo:mlr1664 penicillin binding protein. (695 aa) |
| | Oant_3486 | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: bmb:BruAb2_0742 hypothetical glyoxalase. (258 aa) |
| | Oant_3491 | PFAM: glycoside hydrolase family 25; KEGG: bms:BRA0487 glycosyl hydrolase, family 25. (355 aa) |
| | Oant_3553 | PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: bms:BRA0526 2-oxoisovalerate dehydrogenase E2 component, dihydrolipoamide acetyltransferase. (437 aa) |
| | glmS | Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (607 aa) |
| | glmU | Nucleotidyl transferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (454 aa) |
| | pyrB | TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: bmb:BruAb2_0625 PyrB, aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (322 aa) |
| | Oant_3836 | Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: bme:BMEII0573 transcriptional regulator, RpiR family. (277 aa) |
| | Oant_3876 | Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: bmb:BruAb2_0501 transcriptional regulator, hypothetical. (276 aa) |
| | Oant_3892 | Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: bms:BRA0744 transcriptional regulator, RpiR family. (293 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (491 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (232 aa) |
| | Oant_3961 | PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: rpc:RPC_0034 metal dependent phosphohydrolase. (197 aa) |
| | Oant_4003 | TIGRFAM: benzoate-CoA ligase family; PFAM: AMP-dependent synthetase and ligase; KEGG: bja:bll6076 putative acetyl-CoA synthetase. (542 aa) |
| | Oant_4146 | PFAM: NUDIX hydrolase; KEGG: pat:Patl_1523 NUDIX hydrolase. (180 aa) |
| | Oant_4164 | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: pae:PA1672 hypothetical protein. (120 aa) |
| | Oant_4195 | PFAM: Lytic transglycosylase catalytic; KEGG: bmb:BruAb2_1078 hypothetical protein. (180 aa) |
| | Oant_4214 | TIGRFAM: ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; SMART: AAA ATPase; KEGG: bmb:BruAb2_0127 flagellum-specific ATP synthase FliI. (452 aa) |
| | Oant_4233 | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (470 aa) |
| | Oant_4237 | PFAM: O-antigen polymerase; KEGG: bms:BRA0108 exopolysaccharide production protein, putative. (429 aa) |
| | Oant_4239 | KEGG: bmb:BruAb2_0104 hypothetical protein. (400 aa) |
| | Oant_4240 | TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF; KEGG: bms:BRA0104 glycosyl transferase, WecB/TagA/CpsF family; Belongs to the glycosyltransferase 26 family. (252 aa) |
| | Oant_4258 | PFAM: protein of unknown function DUF882; Peptidase M15A; KEGG: bms:BRA0083 hypothetical protein. (636 aa) |
| | Oant_4269 | TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: bme:BMEII0021 polysialic acid capsule expression protein KpsF; Belongs to the SIS family. GutQ/KpsF subfamily. (354 aa) |
| | Oant_4272 | TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: bmb:BruAb2_0071 GalU, UTP--glucose-1-phosphate uridylyltransferase. (297 aa) |
| | Oant_4414 | PFAM: UDP-glucose/GDP-mannose dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: bmb:BruAb2_0677 Ugd, UDP-glucose 6-dehydrogenase. (478 aa) |
| | Oant_4415 | KEGG: bmb:BruAb2_0678 glycosyl transferase, group 2 family protein. (616 aa) |
| | Oant_4417 | PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; KEGG: bms:BRA0542 NAD-dependent epimerase/dehydratase family protein. (336 aa) |
