(12 nodes) Anaphase-promoting complex, and Spindle checkpoint signaling network (Cryptosporidium muris)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CMU_022740	Separase, putative. (2821 aa)
	CMU_007570	Uncharacterized protein. (2023 aa)
	CMU_008030	Anaphase-promoting complex, subunit 10 family protein. (227 aa)
	CMU_009640	WD_REPEATS_REGION domain-containing protein. (403 aa)
	CMU_013700	TPR repeat-containing protein. (803 aa)
	CMU_014610	Dual specificity protein phosphatase CDC14A, putative. (455 aa)
	CMU_033430	TPR repeat-containing protein. (666 aa)
	CMU_034030	Protein kinase domain-containing protein. (856 aa)
	CMU_000910	TPR repeat-containing protein. (583 aa)
	CMU_036220	Protein kinase domain-containing protein. (528 aa)
	CMU_029430	Zinc finger, C3HC4 type domain-containing protein. (98 aa)
	CMU_019890	WD_REPEATS_REGION domain-containing protein. (454 aa)

Your Current Organism:

Cryptosporidium muris

NCBI taxonomy Id: 441375
Other names: C. muris RN66, Cryptosporidium muris RN66

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CMU_000910	CMU_007570	B6AG80	B6ADH6	TPR repeat-containing protein.	Uncharacterized protein.	0.999
CMU_000910	CMU_008030	B6AG80	B6ADM1	TPR repeat-containing protein.	Anaphase-promoting complex, subunit 10 family protein.	0.999
CMU_000910	CMU_009640	B6AG80	B6AE31	TPR repeat-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.944
CMU_000910	CMU_013700	B6AG80	B6AES8	TPR repeat-containing protein.	TPR repeat-containing protein.	0.999
CMU_000910	CMU_014610	B6AG80	B6AF18	TPR repeat-containing protein.	Dual specificity protein phosphatase CDC14A, putative.	0.870
CMU_000910	CMU_019890	B6AG80	B6AJA8	TPR repeat-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.999
CMU_000910	CMU_022740	B6AG80	B6ABR6	TPR repeat-containing protein.	Separase, putative.	0.908
CMU_000910	CMU_029430	B6AG80	B6AI27	TPR repeat-containing protein.	Zinc finger, C3HC4 type domain-containing protein.	0.999
CMU_000910	CMU_033430	B6AG80	B6AFG7	TPR repeat-containing protein.	TPR repeat-containing protein.	0.999
CMU_000910	CMU_034030	B6AG80	B6AFM7	TPR repeat-containing protein.	Protein kinase domain-containing protein.	0.997
CMU_000910	CMU_036220	B6AG80	B6AGV8	TPR repeat-containing protein.	Protein kinase domain-containing protein.	0.915
CMU_007570	CMU_000910	B6ADH6	B6AG80	Uncharacterized protein.	TPR repeat-containing protein.	0.999
CMU_007570	CMU_008030	B6ADH6	B6ADM1	Uncharacterized protein.	Anaphase-promoting complex, subunit 10 family protein.	0.999
CMU_007570	CMU_009640	B6ADH6	B6AE31	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.906
CMU_007570	CMU_013700	B6ADH6	B6AES8	Uncharacterized protein.	TPR repeat-containing protein.	0.999
CMU_007570	CMU_014610	B6ADH6	B6AF18	Uncharacterized protein.	Dual specificity protein phosphatase CDC14A, putative.	0.884
CMU_007570	CMU_019890	B6ADH6	B6AJA8	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.997
CMU_007570	CMU_022740	B6ADH6	B6ABR6	Uncharacterized protein.	Separase, putative.	0.704
CMU_007570	CMU_029430	B6ADH6	B6AI27	Uncharacterized protein.	Zinc finger, C3HC4 type domain-containing protein.	0.999
CMU_007570	CMU_033430	B6ADH6	B6AFG7	Uncharacterized protein.	TPR repeat-containing protein.	0.999