(38 nodes) Proteasome network (Cryptosporidium muris)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CMU_035560	Uncharacterized protein. (84 aa)
	CMU_012360	Proteasome subunit alpha type. (251 aa)
	CMU_015340	26S proteasome subunit 4, putative; Belongs to the AAA ATPase family. (447 aa)
	CMU_037910	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (279 aa)
	CMU_039430	Nas2_N domain-containing protein. (211 aa)
	CMU_040010	Proteasome subunit alpha type. (255 aa)
	CMU_041440	RPN13_C domain-containing protein. (259 aa)
	CMU_024510	Proteasome/cyclosome repeat family protein. (972 aa)
	CMU_024750	26S proteasome regulatory subunit S10B, putative; Belongs to the AAA ATPase family. (391 aa)
	CMU_027300	26S protease regulatory subunit 8, putative; Belongs to the AAA ATPase family. (396 aa)
	CMU_022870	Mov34/MPN/PAD-1 family protein. (323 aa)
	CMU_023610	Proteasome activator pa28 beta subunit family protein. (236 aa)
	CMU_015940	Proteasome subunit beta type 4, putative. (269 aa)
	CMU_016810	PCI domain-containing protein. (419 aa)
	CMU_017560	26S proteasome regulatory subunit 6b, putative; Belongs to the AAA ATPase family. (397 aa)
	CMU_008970	26S proteasome regulatory subunit 6A, putative; Belongs to the AAA ATPase family. (425 aa)
	CMU_009350	PCI domain-containing protein. (444 aa)
	CMU_009870	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (194 aa)
	CMU_009520	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (213 aa)
	CMU_035100	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (201 aa)
	CMU_000900	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (282 aa)
	CMU_001290	Uncharacterized protein. (129 aa)
	CMU_001330	Proteasome subunit alpha type. (251 aa)
	CMU_001360	Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (252 aa)
	CMU_022160	Proteasome/cyclosome repeat family protein; Belongs to the proteasome subunit S1 family. (1108 aa)
	CMU_036270	PCI domain-containing protein. (552 aa)
	CMU_036920	Proteasome subunit alpha type. (261 aa)
	CMU_037090	PCI domain-containing protein. (394 aa)
	CMU_005580	PCI domain-containing protein. (529 aa)
	CMU_029260	Proteasome subunit beta type 1, putative. (245 aa)
	CMU_031340	Mov34/MPN/PAD-1 family proteasome regulatory subunit, putative. (315 aa)
	CMU_020410	26S proteasome regulatory subunit 7, putative; Belongs to the AAA ATPase family. (431 aa)
	CMU_003410	SAC3/GANP family protein. (283 aa)
	CMU_035000	Oxysterol-binding protein, putative. (635 aa)
	CMU_013680	Proteasome subunit alpha type. (236 aa)
	CMU_013390	Proteasome subunit alpha type. (241 aa)
	CMU_012650	Ubiquitin interaction motif family protein. (361 aa)
	CMU_012560	Uncharacterized protein. (2278 aa)

Your Current Organism:

Cryptosporidium muris

NCBI taxonomy Id: 441375
Other names: C. muris RN66, Cryptosporidium muris RN66

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CMU_000900	CMU_001290	B6AG79	B6AGB7	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Uncharacterized protein.	0.998
CMU_000900	CMU_001330	B6AG79	B6AGC1	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Proteasome subunit alpha type.	0.999
CMU_000900	CMU_001360	B6AG79	B6AGC4	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Proteasome endopeptidase complex; Belongs to the peptidase T1A family.	0.999
CMU_000900	CMU_003410	B6AG79	B6AJX0	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	SAC3/GANP family protein.	0.994
CMU_000900	CMU_005580	B6AG79	B6AHE0	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	PCI domain-containing protein.	0.994
CMU_000900	CMU_008970	B6AG79	B6ADW4	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	26S proteasome regulatory subunit 6A, putative; Belongs to the AAA ATPase family.	0.997
CMU_000900	CMU_009350	B6AG79	B6AE02	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	PCI domain-containing protein.	0.997
CMU_000900	CMU_009520	B6AG79	B6AE19	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	0.999
CMU_000900	CMU_009870	B6AG79	B6AE54	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	0.999
CMU_000900	CMU_012360	B6AG79	B6AEE5	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Proteasome subunit alpha type.	0.999
CMU_000900	CMU_012560	B6AG79	B6AEG5	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Uncharacterized protein.	0.968
CMU_000900	CMU_012650	B6AG79	B6AEH4	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Ubiquitin interaction motif family protein.	0.999
CMU_000900	CMU_013390	B6AG79	B6AEP7	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Proteasome subunit alpha type.	0.999
CMU_000900	CMU_013680	B6AG79	B6AES6	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Proteasome subunit alpha type.	0.999
CMU_000900	CMU_015340	B6AG79	B6AEB1	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	26S proteasome subunit 4, putative; Belongs to the AAA ATPase family.	0.997
CMU_000900	CMU_015940	B6AG79	B6ACJ2	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Proteasome subunit beta type 4, putative.	0.999
CMU_000900	CMU_016810	B6AG79	B6ACS6	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	PCI domain-containing protein.	0.998
CMU_000900	CMU_017560	B6AG79	B6ACZ9	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	26S proteasome regulatory subunit 6b, putative; Belongs to the AAA ATPase family.	0.997
CMU_000900	CMU_020410	B6AG79	B6AJ60	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	26S proteasome regulatory subunit 7, putative; Belongs to the AAA ATPase family.	0.999
CMU_000900	CMU_022160	B6AG79	B6AK43	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	Proteasome/cyclosome repeat family protein; Belongs to the proteasome subunit S1 family.	0.996