(94 nodes) Protein processing in endoplasmic reticulum network (Cryptosporidium muris)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CMU_038870	FHA domain-containing protein. (235 aa)
	CMU_039510	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (130 aa)
	CMU_039570	Thioredoxin family protein. (322 aa)
	CMU_039790	PITH domain-containing protein. (185 aa)
	CMU_040610	Translocation protein Sec62, putative. (385 aa)
	CMU_041260	Thioredoxin family protein. (180 aa)
	CMU_041830	Sec23/Sec24 trunk domain-containing protein. (891 aa)
	CMU_024840	RING-type domain-containing protein. (129 aa)
	CMU_025180	Sec23/Sec24 zinc finger domain-containing protein. (1103 aa)
	CMU_025250	Calpain family cysteine protease domain-containing protein; Belongs to the peptidase C2 family. (897 aa)
	CMU_026570	Zinc finger, C3HC4 type domain-containing protein. (637 aa)
	CMU_026850	DnaJ domain-containing protein. (382 aa)
	CMU_027380	Thioredoxin family protein. (485 aa)
	CMU_027700	Protein kinase domain-containing protein. (1377 aa)
	CMU_028090	Disulfide isomerase protein, putative. (478 aa)
	CMU_023730	Endoplasmic reticulum oxidoreductin 1 family protein. (407 aa)
	CMU_018930	Glyco_transf_24 domain-containing protein. (2132 aa)
	CMU_019150	UBA/TS-N domain-containing protein. (469 aa)
	CMU_019240	Thioredoxin family protein. (566 aa)
	CMU_019420	Eukaryotic translation initiation factor 2 alpha subunit family protein. (338 aa)
	CMU_015720	DnaJ domain-containing protein. (403 aa)
	CMU_015830	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (215 aa)
	CMU_016800	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (276 aa)
	CMU_016880	Thioredoxin family protein. (564 aa)
	CMU_017310	Phospholipase A-2-activating protein, putative. (841 aa)
	CMU_017350	Ubiquitin family protein. (364 aa)
	CMU_017850	DnaJ domain-containing protein. (360 aa)
	CMU_017870	DnaJ domain-containing protein. (262 aa)
	CMU_018260	Cullin family protein; Belongs to the cullin family. (792 aa)
	CMU_007180	DnaJ domain-containing protein. (270 aa)
	CMU_007380	Sulfhydryl oxidase. (675 aa)
	CMU_007850	Oligosaccharyl transferase STT3 subunit family protein. (741 aa)
	CMU_008890	DnaJ domain-containing protein. (349 aa)
	CMU_009770	Sec61beta family protein. (62 aa)
	CMU_009950	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family. (681 aa)
	CMU_015230	Thioredoxin family protein. (615 aa)
	CMU_015270	WD_REPEATS_REGION domain-containing protein. (446 aa)
	CMU_015370	Ubiquitin fusion degradation protein 1, putative. (300 aa)
	CMU_012370	WD_REPEATS_REGION domain-containing protein. (1225 aa)
	CMU_012700	Ubiquitin-conjugating enzyme family protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
	CMU_012950	Yip1 domain-containing protein. (369 aa)
	CMU_012980	Heat shock 40 kDa protein, putative. (330 aa)
	CMU_013010	Uncharacterized protein. (438 aa)
	CMU_013170	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] (488 aa)
	CMU_013690	Hsp90 protein, putative. (832 aa)
	CMU_013720	Zinc finger, C3HC4 type domain-containing protein. (685 aa)
	CMU_013760	DnaJ domain-containing protein. (807 aa)
	CMU_013960	DnaJ domain-containing protein. (638 aa)
	CMU_014210	Protein disulfide-isomerase domain-containing protein; Belongs to the protein disulfide isomerase family. (424 aa)
	CMU_014230	Zinc finger, C3HC4 type domain-containing protein. (758 aa)
	CMU_014340	Protein translocation complex, SEC61 gamma subunit, putative. (82 aa)
	CMU_014900	UV excision repair protein Rad23, putative. (347 aa)
	CMU_032900	Protein-transport Sec61 protein subunit alpha, putative; Belongs to the SecY/SEC61-alpha family. (473 aa)
	CMU_033800	Ubiquitin-like domain-containing protein. (110 aa)
	CMU_034000	NPL4 family protein. (489 aa)
	CMU_034380	Small GTP-binding protein sar1, putative; Belongs to the small GTPase superfamily. SAR1 family. (192 aa)
	CMU_034580	Suppressor of kinetochore protein 1, putative; Belongs to the SKP1 family. (161 aa)
	CMU_034830	Uncharacterized protein; Belongs to the WD repeat SEC13 family. (368 aa)
	CMU_034960	Ubiquitin carboxyl-terminal hydrolase family protein; Belongs to the peptidase C19 family. (479 aa)
	CMU_035010	Transitional endoplasmic reticulum ATPase protein, putative. (802 aa)
	CMU_035020	Josephin family protein. (392 aa)
	CMU_035090	Ubiquitin-conjugating enzyme family protein; Belongs to the ubiquitin-conjugating enzyme family. (166 aa)
	CMU_000120	Protein kinase domain-containing protein. (1538 aa)
	CMU_000140	CBF domain-containing protein. (678 aa)
	CMU_000230	Ribosomal protein L7Ae domain-containing protein. (1110 aa)
	CMU_000730	DnaJ domain-containing protein. (678 aa)
	CMU_001050	U-box domain-containing protein. (1075 aa)
	CMU_001750	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (724 aa)
	CMU_001840	UBX domain-containing protein. (230 aa)
	CMU_001940	Uncharacterized protein. (1424 aa)
	CMU_035510	Thioredoxin family protein. (597 aa)
	CMU_036690	Zinc finger, C3HC4 type domain-containing protein. (216 aa)
	CMU_036950	Uncharacterized protein. (317 aa)
	CMU_037290	Zinc finger, C3HC4 type domain-containing protein. (149 aa)
	CMU_005520	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (642 aa)
	CMU_005790	Ubiquitin-conjugating enzyme family protein. (313 aa)
	CMU_005860	DnaJ domain-containing protein. (423 aa)
	CMU_006110	PITH domain-containing protein. (172 aa)
	CMU_006530	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family. (654 aa)
	CMU_029740	XAP5 domain-containing protein. (280 aa)
	CMU_029760	DnaJ domain-containing protein. (336 aa)
	CMU_031230	Uncharacterized protein. (762 aa)
	CMU_031920	Hsp90 protein, putative. (705 aa)
	CMU_031980	PUB domain-containing protein. (614 aa)
	CMU_032100	PUB domain-containing protein. (339 aa)
	CMU_032240	UAS domain-containing protein. (321 aa)
	CMU_011250	Zinc finger C3HC4/FHA domain-containing protein. (542 aa)
	CMU_011420	DnaJ domain-containing protein. (539 aa)
	CMU_011750	OST3 / OST6 family protein. (340 aa)
	CMU_021530	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (500 aa)
	CMU_021630	Legume-like lectin family protein. (485 aa)
	CMU_003190	Uncharacterized protein. (660 aa)
	CMU_003270	DnaJ / Thioredoxin domain-containing protein. (579 aa)
	CMU_003370	DnaK family protein. (910 aa)

Your Current Organism:

Cryptosporidium muris

NCBI taxonomy Id: 441375
Other names: C. muris RN66, Cryptosporidium muris RN66

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CMU_000120	CMU_013690	B6AG02	B6AES7	Protein kinase domain-containing protein.	Hsp90 protein, putative.	0.417
CMU_000120	CMU_019420	B6AG02	B6ACC9	Protein kinase domain-containing protein.	Eukaryotic translation initiation factor 2 alpha subunit family protein.	0.992
CMU_000120	CMU_031920	B6AG02	B6AIL0	Protein kinase domain-containing protein.	Hsp90 protein, putative.	0.417
CMU_000120	CMU_032900	B6AG02	B6AFB4	Protein kinase domain-containing protein.	Protein-transport Sec61 protein subunit alpha, putative; Belongs to the SecY/SEC61-alpha family.	0.421
CMU_000140	CMU_007850	B6AG04	B6ADK3	CBF domain-containing protein.	Oligosaccharyl transferase STT3 subunit family protein.	0.416
CMU_000230	CMU_000730	B6AG12	B6AG62	Ribosomal protein L7Ae domain-containing protein.	DnaJ domain-containing protein.	0.564
CMU_000230	CMU_003270	B6AG12	B6AJV6	Ribosomal protein L7Ae domain-containing protein.	DnaJ / Thioredoxin domain-containing protein.	0.564
CMU_000230	CMU_003370	B6AG12	B6AJW6	Ribosomal protein L7Ae domain-containing protein.	DnaK family protein.	0.794
CMU_000230	CMU_006530	B6AG12	B6AHN5	Ribosomal protein L7Ae domain-containing protein.	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family.	0.843
CMU_000230	CMU_009950	B6AG12	B6AE62	Ribosomal protein L7Ae domain-containing protein.	Heat shock protein 70, putative; Belongs to the heat shock protein 70 family.	0.529
CMU_000230	CMU_011750	B6AG12	B6AJ32	Ribosomal protein L7Ae domain-containing protein.	OST3 / OST6 family protein.	0.435
CMU_000230	CMU_013010	B6AG12	B6AEL0	Ribosomal protein L7Ae domain-containing protein.	Uncharacterized protein.	0.435
CMU_000230	CMU_013170	B6AG12	B6AEM5	Ribosomal protein L7Ae domain-containing protein.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]	0.467
CMU_000230	CMU_013690	B6AG12	B6AES7	Ribosomal protein L7Ae domain-containing protein.	Hsp90 protein, putative.	0.469
CMU_000230	CMU_014210	B6AG12	B6AEX8	Ribosomal protein L7Ae domain-containing protein.	Protein disulfide-isomerase domain-containing protein; Belongs to the protein disulfide isomerase family.	0.435
CMU_000230	CMU_023730	B6AG12	B6AC15	Ribosomal protein L7Ae domain-containing protein.	Endoplasmic reticulum oxidoreductin 1 family protein.	0.777
CMU_000230	CMU_031920	B6AG12	B6AIL0	Ribosomal protein L7Ae domain-containing protein.	Hsp90 protein, putative.	0.469
CMU_000230	CMU_032900	B6AG12	B6AFB4	Ribosomal protein L7Ae domain-containing protein.	Protein-transport Sec61 protein subunit alpha, putative; Belongs to the SecY/SEC61-alpha family.	0.479
CMU_000230	CMU_035010	B6AG12	B6AFX4	Ribosomal protein L7Ae domain-containing protein.	Transitional endoplasmic reticulum ATPase protein, putative.	0.436
CMU_000230	CMU_039570	B6AG12	B6A9J7	Ribosomal protein L7Ae domain-containing protein.	Thioredoxin family protein.	0.435