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Mpop_0052 Mpop_0052 Mpop_0259 Mpop_0259 Mpop_0358 Mpop_0358 Mpop_0364 Mpop_0364 Mpop_0366 Mpop_0366 Mpop_0368 Mpop_0368 Mpop_0374 Mpop_0374 fabA fabA Mpop_0495 Mpop_0495 Mpop_0497 Mpop_0497 Mpop_0527 Mpop_0527 Mpop_0528 Mpop_0528 acpP acpP Mpop_0530 Mpop_0530 Mpop_1003 Mpop_1003 Mpop_1029 Mpop_1029 Mpop_1030 Mpop_1030 Mpop_1101 Mpop_1101 Mpop_1222 Mpop_1222 Mpop_1251 Mpop_1251 Mpop_1252 Mpop_1252 Mpop_1276 Mpop_1276 Mpop_1292 Mpop_1292 Mpop_1481 Mpop_1481 Mpop_1482 Mpop_1482 Mpop_1483 Mpop_1483 Mpop_1677 Mpop_1677 Mpop_1699 Mpop_1699 Mpop_1700 Mpop_1700 Mpop_1701 Mpop_1701 Mpop_1838 Mpop_1838 Mpop_1913 Mpop_1913 fabH fabH Mpop_2031 Mpop_2031 Mpop_2089 Mpop_2089 Mpop_2090 Mpop_2090 Mpop_2186 Mpop_2186 Mpop_2345 Mpop_2345 acsA acsA Mpop_2775 Mpop_2775 Mpop_2785 Mpop_2785 Mpop_3043 Mpop_3043 Mpop_3044 Mpop_3044 Mpop_3181 Mpop_3181 Mpop_3235 Mpop_3235 Mpop_3437 Mpop_3437 Mpop_3440 Mpop_3440 Mpop_3441 Mpop_3441 Mpop_3444 Mpop_3444 Mpop_3612 Mpop_3612 Mpop_3616 Mpop_3616 Mpop_3621 Mpop_3621 Mpop_3622 Mpop_3622 Mpop_3623 Mpop_3623 Mpop_3642 Mpop_3642 Mpop_3667 Mpop_3667 Mpop_3939 Mpop_3939 Mpop_4016 Mpop_4016 Mpop_4017 Mpop_4017 Mpop_4018 Mpop_4018 Mpop_4019 Mpop_4019 Mpop_4020 Mpop_4020 Mpop_4022 Mpop_4022 Mpop_4037 Mpop_4037 Mpop_4211 Mpop_4211 Mpop_4215 Mpop_4215 Mpop_4289 Mpop_4289 Mpop_4290 Mpop_4290 Mpop_4291 Mpop_4291 Mpop_4292 Mpop_4292 Mpop_4334 Mpop_4334 Mpop_4452 Mpop_4452 Mpop_4586 Mpop_4586 Mpop_4756 Mpop_4756 Mpop_4767 Mpop_4767 Mpop_4781 Mpop_4781 Mpop_4810 Mpop_4810 Mpop_4946 Mpop_4946 accD accD Mpop_5057 Mpop_5057 Mpop_5058 Mpop_5058 Mpop_5059 Mpop_5059 Mpop_5060 Mpop_5060 Mpop_5061 Mpop_5061 Mpop_5162 Mpop_5162 Mpop_5163 Mpop_5163 Mpop_5190 Mpop_5190 fabZ fabZ Mpop_5267 Mpop_5267 Mpop_5269 Mpop_5269 accA accA Mpop_5337 Mpop_5337
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Mpop_0052KEGG: mex:Mext_0030 acyl transferase domain protein. (307 aa)
Mpop_0259PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_2090 short-chain dehydrogenase/reductase SDR. (249 aa)
Mpop_0358PFAM: carboxyl transferase; KEGG: mex:Mext_0282 carboxyl transferase. (510 aa)
Mpop_0364TIGRFAM: crotonyl-CoA reductase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: mex:Mext_0288 crotonyl-CoA reductase. (432 aa)
Mpop_0366KEGG: mex:Mext_0290 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. (688 aa)
Mpop_0368PFAM: short-chain dehydrogenase/reductase SDR; Male sterility domain; KR domain protein; KEGG: mex:Mext_0292 short-chain dehydrogenase/reductase SDR. (248 aa)
Mpop_0374TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; KEGG: mex:Mext_0298 LAO/AO transport system ATPase. (329 aa)
fabABeta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (179 aa)
Mpop_0495PFAM: Beta-ketoacyl synthase; KEGG: mex:Mext_0425 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (408 aa)
Mpop_0497KEGG: mex:Mext_0426 short-chain dehydrogenase/reductase SDR. (277 aa)
Mpop_0527TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: mex:Mext_0556 malonyl CoA-acyl carrier protein transacylase. (310 aa)
Mpop_05283-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (246 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (78 aa)
Mpop_05303-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (420 aa)
Mpop_1003KEGG: mex:Mext_1069 methylmalonyl-CoA epimerase; TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase. (134 aa)
Mpop_1029acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (158 aa)
Mpop_1030acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (455 aa)
Mpop_1101PFAM: AMP-dependent synthetase and ligase; KEGG: mex:Mext_1713 AMP-dependent synthetase and ligase. (518 aa)
Mpop_1222PFAM: cytochrome P450; KEGG: mex:Mext_1270 cytochrome P450. (452 aa)
Mpop_1251PFAM: Aldehyde Dehydrogenase_; KEGG: xau:Xaut_1357 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (480 aa)
Mpop_1252PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: dsh:Dshi_1429 short-chain dehydrogenase/reductase SDR. (248 aa)
Mpop_1276PFAM: Enoyl-CoA hydratase/isomerase; KEGG: mlo:mll5584 enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
Mpop_1292CypC; KEGG: bay:RBAM_011070 CypC. (424 aa)
Mpop_1481PFAM: beta-lactamase; KEGG: mex:Mext_1480 beta-lactamase. (405 aa)
Mpop_1482PFAM: 4'-phosphopantetheinyl transferase; KEGG: mex:Mext_1481 4'-phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. (239 aa)
Mpop_1483PFAM: NUDIX hydrolase; KEGG: mex:Mext_1482 NUDIX hydrolase. (148 aa)
Mpop_1677PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: mex:Mext_1564 thiamine pyrophosphate protein domain protein TPP-binding; Belongs to the TPP enzyme family. (577 aa)
Mpop_1699PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: mex:Mext_1544 3-hydroxybutyryl-CoA dehydrogenase. (293 aa)
Mpop_1700PFAM: Electron transfer flavoprotein alpha/beta-subunit; Electron transfer flavoprotein alpha subunit; KEGG: mex:Mext_1543 electron transfer flavoprotein alpha subunit. (317 aa)
Mpop_1701PFAM: Electron transfer flavoprotein alpha/beta-subunit; KEGG: mex:Mext_1542 electron transfer flavoprotein alpha/beta-subunit. (249 aa)
Mpop_1838Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: mex:Mext_1947 beta-ketoacyl synthase. (2468 aa)
Mpop_1913PFAM: AMP-dependent synthetase and ligase; KEGG: mex:Mext_1958 AMP-dependent synthetase and ligase. (640 aa)
fabH3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (326 aa)
Mpop_2031PFAM: coenzyme A transferase; KEGG: mex:Mext_2071 coenzyme A transferase. (660 aa)
Mpop_2089KEGG: mex:Mext_2131 hypothetical protein. (427 aa)
Mpop_2090PFAM: glycosyl transferase family 28; KEGG: mex:Mext_2132 glycosyl transferase family 28. (424 aa)
Mpop_2186PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: mex:Mext_2228 acyl-CoA dehydrogenase domain protein. (562 aa)
Mpop_2345PFAM: methylmalonyl-CoA mutase; KEGG: mex:Mext_2388 methylmalonyl-CoA mutase. (605 aa)
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (649 aa)
Mpop_2775PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: mex:Mext_2653 6-phosphogluconate dehydrogenase NAD-binding. (288 aa)
Mpop_2785PFAM: cytochrome P450; KEGG: mex:Mext_2663 cytochrome P450. (467 aa)
Mpop_3043KEGG: mex:Mext_2919 3-oxoacid CoA-transferase, A subunit; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase. (255 aa)
Mpop_3044KEGG: mex:Mext_2920 3-oxoacid CoA-transferase, B subunit; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase. (241 aa)
Mpop_3181Carbamoyl-phosphate synthase L chain ATP-binding; PFAM: biotin/lipoyl attachment domain-containing protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; RimK domain protein ATP-grasp; KEGG: mex:Mext_2996 carbamoyl-phosphate synthase L chain ATP-binding. (667 aa)
Mpop_3235PFAM: membrane bound O-acyl transferase MBOAT family protein; KEGG: mex:Mext_3038 membrane bound O-acyl transferase MBOAT family protein; Belongs to the membrane-bound acyltransferase family. (457 aa)
Mpop_3437PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mex:Mext_3241 3-hydroxyacyl-CoA dehydrogenase NAD-binding. (733 aa)
Mpop_3440KEGG: mex:Mext_3244 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
Mpop_3441PFAM: acyl-CoA dehydrogenase domain protein; KEGG: mex:Mext_3245 acyl-CoA dehydrogenase domain protein. (596 aa)
Mpop_3444KEGG: mex:Mext_3248 hypothetical protein. (314 aa)
Mpop_3612PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_3419 short-chain dehydrogenase/reductase SDR. (246 aa)
Mpop_3616PFAM: Aldehyde Dehydrogenase_; KEGG: mex:Mext_3423 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (507 aa)
Mpop_3621PFAM: AMP-dependent synthetase and ligase; KEGG: mex:Mext_3426 AMP-dependent synthetase and ligase. (505 aa)
Mpop_3622KEGG: mex:Mext_3427 hypothetical protein. (83 aa)
Mpop_3623PFAM: DoxX family protein; KEGG: mex:Mext_3428 DoxX family protein. (174 aa)
Mpop_3642PFAM: MaoC domain protein dehydratase; KEGG: mex:Mext_3444 MaoC domain protein dehydratase. (157 aa)
Mpop_3667KEGG: mex:Mext_3469 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
Mpop_3939PFAM: AMP-dependent synthetase and ligase; KEGG: mex:Mext_3653 AMP-dependent synthetase and ligase. (585 aa)
Mpop_4016PFAM: IucA/IucC family protein; KEGG: mex:Mext_3760 IucA/IucC family protein. (595 aa)
Mpop_4017IucA/IucC family protein; PFAM: AMP-dependent synthetase and ligase; IucA/IucC family protein; KEGG: mex:Mext_3761 IucA/IucC family protein. (991 aa)
Mpop_4018KEGG: mex:Mext_3762 hypothetical protein. (437 aa)
Mpop_4019PFAM: Xylose isomerase domain protein TIM barrel; KEGG: mex:Mext_3763 xylose isomerase domain protein TIM barrel. (278 aa)
Mpop_4020KEGG: mex:Mext_3764 hypothetical protein. (92 aa)
Mpop_4022KEGG: mex:Mext_3766 hypothetical protein. (229 aa)
Mpop_4037PFAM: MaoC domain protein dehydratase; KEGG: mex:Mext_3781 MaoC domain protein dehydratase. (348 aa)
Mpop_4211PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mag:amb2106 dehydrogenase with different specificities. (274 aa)
Mpop_4215TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: mex:Mext_1282 methylmalonate-semialdehyde dehydrogenase. (499 aa)
Mpop_4289PFAM: Enoyl-CoA hydratase/isomerase; KEGG: mex:Mext_3610 enoyl-CoA hydratase/isomerase. (254 aa)
Mpop_4290PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mex:Mext_3611 short-chain dehydrogenase/reductase SDR. (283 aa)
Mpop_4291PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mex:Mext_3612 short-chain dehydrogenase/reductase SDR. (289 aa)
Mpop_4292PFAM: Mg2 transporter protein CorA family protein; KEGG: mex:Mext_3613 magnesium and cobalt transport protein CorA. (334 aa)
Mpop_4334TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: mex:Mext_3877 quinone oxidoreductase, YhdH/YhfP family. (334 aa)
Mpop_4452Non-ribosomal peptide synthetase; TIGRFAM: amino acid adenylation domain protein; non-ribosomal peptide synthetase; PFAM: AMP-dependent synthetase and ligase; transferase hexapeptide repeat containing protein; KEGG: mex:Mext_3972 non-ribosomal peptide synthetase; Belongs to the ATP-dependent AMP-binding enzyme family. (1395 aa)
Mpop_4586PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: mex:Mext_4104 acyl-CoA dehydrogenase domain protein. (587 aa)
Mpop_4756PFAM: Enoyl-CoA hydratase/isomerase; KEGG: mex:Mext_4237 enoyl-CoA hydratase/isomerase. (409 aa)
Mpop_4767Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone. (557 aa)
Mpop_4781PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: mex:Mext_4266 acyl-CoA dehydrogenase domain protein. (418 aa)
Mpop_4810KEGG: mex:Mext_4292 enoyl-acyl carrier protein reductase. (275 aa)
Mpop_4946PFAM: AMP-dependent synthetase and ligase; KEGG: mex:Mext_4434 AMP-dependent synthetase and ligase. (539 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (306 aa)
Mpop_5057PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mex:Mext_4544 short-chain dehydrogenase/reductase SDR. (253 aa)
Mpop_5058PFAM: Beta-ketoacyl synthase; KEGG: mex:Mext_4545 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (428 aa)
Mpop_5059PFAM: Beta-ketoacyl synthase; KEGG: mex:Mext_4546 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (386 aa)
Mpop_5060PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: mex:Mext_4547 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ. (154 aa)
Mpop_5061PFAM: phosphopantetheine-binding; KEGG: mex:Mext_4548 phosphopantetheine-binding. (98 aa)
Mpop_5162PFAM: condensation domain protein; phosphopantetheine-binding; KEGG: mex:Mext_4624 aspartate racemase. (843 aa)
Mpop_5163TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; KEGG: mex:Mext_4625 amino acid adenylation domain protein. (1174 aa)
Mpop_5190PFAM: Enoyl-CoA hydratase/isomerase; KEGG: mex:Mext_4649 enoyl-CoA hydratase/isomerase. (274 aa)
fabZBeta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (153 aa)
Mpop_5267PFAM: Malonyl-CoA decarboxylase; KEGG: mex:Mext_4728 malonyl-CoA decarboxylase. (469 aa)
Mpop_5269TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mex:Mext_4730 3-hydroxybutyrate dehydrogenase. (261 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (320 aa)
Mpop_5337KEGG: mex:Mext_4794 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. (721 aa)
Your Current Organism:
Methylorubrum populi
NCBI taxonomy Id: 441620
Other names: M. populi BJ001, Methylobacterium populi BJ001, Methylobacterium sp. BJ001, Methylorubrum populi BJ001
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