(66 nodes) Steroid biosynthetic process, and Carbon-nitrogen ligase activity, with glutamine as amido-N-donor network (Talaromyces stipitatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TSTA_064530	NmrA domain-containing protein. (290 aa)
	TSTA_075460	Sterol desaturase family; Belongs to the sterol desaturase family. (321 aa)
	TSTA_077050	3-ketosteroid reductase. (451 aa)
	TSTA_079670	Uncharacterized protein. (135 aa)
	TSTA_062850	Cytochrome P450, putative. (509 aa)
	TSTA_062930	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (317 aa)
	TSTA_068830	Uncharacterized protein; Belongs to the cytochrome P450 family. (586 aa)
	TSTA_096790	Fatty acid oxygenase PpoC, putative. (1125 aa)
	TSTA_089690	14-alpha sterol demethylase Cyp51B; Belongs to the cytochrome P450 family. (522 aa)
	TSTA_093310	Uncharacterized protein. (349 aa)
	TSTA_088420	Hydroxysteroid dehydrogenase, putative. (153 aa)
	TSTA_092450	Uncharacterized protein. (148 aa)
	TSTA_038910	Ergosterol biosynthesis protein Erg28, putative. (142 aa)
	TSTA_039520	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (365 aa)
	TSTA_024420	Farnesyl-diphosphate farnesyltransferase, putative. (471 aa)
	TSTA_024770	Uncharacterized protein. (309 aa)
	TSTA_025400	2-methylcitrate dehydratase, putative. (571 aa)
	TSTA_026640	Cytochrome P450 monooxygenase, putative; Belongs to the cytochrome P450 family. (535 aa)
	TSTA_027230	Siderophore biosynthesis enzyme, putative. (402 aa)
	TSTA_033040	C-14 sterol reductase. (497 aa)
	TSTA_030910	Cytochrome P450, putative; Belongs to the cytochrome P450 family. (525 aa)
	TSTA_036200	Cytochrome P450, putative; Belongs to the cytochrome P450 family. (526 aa)
	TSTA_111850	IQ calmodulin-binding motif protein. (639 aa)
	TSTA_118280	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (739 aa)
	TSTA_118990	LaeA-like methyltransferase, putative. (290 aa)
	TSTA_120860	Uncharacterized protein. (290 aa)
	TSTA_115760	GFA domain-containing protein. (260 aa)
	TSTA_125620	NAD(P)-bd_dom domain-containing protein. (326 aa)
	TSTA_116180	NAD dependent epimerase/dehydratase, putative. (610 aa)
	TSTA_125540	2-methylcitrate dehydratase (PrpD), putative. (491 aa)
	TSTA_120610	Uncharacterized protein. (322 aa)
	TSTA_120640	NAD dependent epimerase/dehydratase, putative. (329 aa)
	TSTA_016950	Cytochrome P450, putative; Belongs to the cytochrome P450 family. (551 aa)
	TSTA_017890	Uncharacterized protein. (375 aa)
	TSTA_017960	Cytochrome P450 sterol C-22 desaturase, putative; Belongs to the cytochrome P450 family. (532 aa)
	TSTA_009800	Uncharacterized protein. (290 aa)
	TSTA_018340	Cytochrome P450 monooxygenase, putative; Belongs to the cytochrome P450 family. (527 aa)
	TSTA_018420	C-8 sterol isomerase (Erg-1), putative. (228 aa)
	TSTA_014100	NAD dependent epimerase/dehydratase, putative. (368 aa)
	TSTA_019450	Epimerase/dehydratase family protein, putative. (371 aa)
	TSTA_041670	Uncharacterized protein. (345 aa)
	TSTA_042230	Fungal_trans domain-containing protein. (542 aa)
	TSTA_042620	Cytochrome P450, putative; Belongs to the cytochrome P450 family. (493 aa)
	TSTA_042760	Hydroxysteroid dehydrogenase, putative. (376 aa)
	TSTA_047530	Sterol desaturase, putative; Belongs to the sterol desaturase family. (363 aa)
	TSTA_048500	Prpd, putative. (474 aa)
	TSTA_044700	Cytochrome P450, putative. (599 aa)
	TSTA_044750	C-24(28) sterol reductase. (573 aa)
	TSTA_097840	Uncharacterized protein. (309 aa)
	TSTA_101760	Uncharacterized protein. (321 aa)
	TSTA_102000	Uncharacterized protein. (582 aa)
	TSTA_102040	Cytochrome P450, putative; Belongs to the cytochrome P450 family. (546 aa)
	TSTA_103870	C-4 methyl sterol oxidase Erg25, putative; Belongs to the sterol desaturase family. (299 aa)
	TSTA_104640	Cytochrome P450, putative; Belongs to the cytochrome P450 family. (359 aa)
	TSTA_104780	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (377 aa)
	TSTA_105710	Methyltransferase SirN-like, putative. (305 aa)
	TSTA_054200	Squalene monooxygenase Erg1. (491 aa)
	TSTA_057280	C-3 sterol dehydrogenase/C-4 decarboxylase. (412 aa)
	TSTA_054910	Uncharacterized protein. (285 aa)
	TSTA_057920	Uncharacterized protein. (208 aa)
	TSTA_002270	Uncharacterized protein. (717 aa)
	TSTA_004630	Uncharacterized protein. (354 aa)
	TSTA_005710	Sterol delta 5,6-desaturase ERG3; Belongs to the sterol desaturase family. (354 aa)
	TSTA_110210	Uncharacterized protein. (65 aa)
	TSTA_008150	Cytochrome P450, putative. (507 aa)
	TSTA_007390	Cytochrome P450 oxidoreductase, putative; Belongs to the cytochrome P450 family. (519 aa)

Your Current Organism:

Talaromyces stipitatus

NCBI taxonomy Id: 441959
Other names: T. stipitatus ATCC 10500, Talaromyces stipitatus ATCC 10500

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TSTA_002270	TSTA_005710	B8MT63	B8MTQ7	Uncharacterized protein.	Sterol delta 5,6-desaturase ERG3; Belongs to the sterol desaturase family.	0.524
TSTA_002270	TSTA_014100	B8MT63	B8MGT2	Uncharacterized protein.	NAD dependent epimerase/dehydratase, putative.	0.604
TSTA_002270	TSTA_018420	B8MT63	B8MGM0	Uncharacterized protein.	C-8 sterol isomerase (Erg-1), putative.	0.656
TSTA_002270	TSTA_019450	B8MT63	B8MH69	Uncharacterized protein.	Epimerase/dehydratase family protein, putative.	0.604
TSTA_002270	TSTA_024420	B8MT63	B8M4C3	Uncharacterized protein.	Farnesyl-diphosphate farnesyltransferase, putative.	0.687
TSTA_002270	TSTA_024770	B8MT63	B8M4G0	Uncharacterized protein.	Uncharacterized protein.	0.819
TSTA_002270	TSTA_033040	B8MT63	B8M5S8	Uncharacterized protein.	C-14 sterol reductase.	0.695
TSTA_002270	TSTA_038910	B8MT63	B8M3U3	Uncharacterized protein.	Ergosterol biosynthesis protein Erg28, putative.	0.624
TSTA_002270	TSTA_039520	B8MT63	B8M411	Uncharacterized protein.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.764
TSTA_002270	TSTA_042760	B8MT63	B8MJY5	Uncharacterized protein.	Hydroxysteroid dehydrogenase, putative.	0.604
TSTA_002270	TSTA_044750	B8MT63	B8ML94	Uncharacterized protein.	C-24(28) sterol reductase.	0.695
TSTA_002270	TSTA_047530	B8MT63	B8MKF0	Uncharacterized protein.	Sterol desaturase, putative; Belongs to the sterol desaturase family.	0.524
TSTA_002270	TSTA_054200	B8MT63	B8MQ18	Uncharacterized protein.	Squalene monooxygenase Erg1.	0.676
TSTA_002270	TSTA_057280	B8MT63	B8MQ90	Uncharacterized protein.	C-3 sterol dehydrogenase/C-4 decarboxylase.	0.604
TSTA_002270	TSTA_062930	B8MT63	B8LXZ1	Uncharacterized protein.	Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.	0.524
TSTA_002270	TSTA_075460	B8MT63	B8LVP4	Uncharacterized protein.	Sterol desaturase family; Belongs to the sterol desaturase family.	0.764
TSTA_002270	TSTA_077050	B8MT63	B8LVX2	Uncharacterized protein.	3-ketosteroid reductase.	0.675
TSTA_002270	TSTA_079670	B8MT63	B8LWX9	Uncharacterized protein.	Uncharacterized protein.	0.624
TSTA_002270	TSTA_088420	B8MT63	B8M2E2	Uncharacterized protein.	Hydroxysteroid dehydrogenase, putative.	0.604
TSTA_002270	TSTA_096790	B8MT63	B8LZK7	Uncharacterized protein.	Fatty acid oxygenase PpoC, putative.	0.435