81 items (Talaromyces marneffei) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	PMAA_036930	Adenosine kinase, putative. (349 aa)
	PMAA_027600	Uncharacterized protein. (255 aa)
	PMAA_027890	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (872 aa)
	PMAA_027900	Kinase-related protein. (236 aa)
	PMAA_037950	Urease accessory protein UreD. (347 aa)
	PMAA_028500	Deoxycytidylate deaminase, putative. (354 aa)
	PMAA_028980	IdgA domain protein. (811 aa)
	PMAA_029300	Uncharacterized protein. (384 aa)
	PMAA_029320	CMP/dCMP-type deaminase domain-containing protein. (162 aa)
	PMAA_021950	Uracil phosphoribosyltransferase. (205 aa)
	PMAA_031900	DUF21 and CBS domain protein (Mam3), putative. (739 aa)
	PMAA_033150	Glutamine amidotransferase type-1 domain-containing protein. (249 aa)
	PMAA_024620	tRNA-specific adenosine deaminase, putative. (1187 aa)
	PMAA_024700	Uncharacterized protein. (627 aa)
	PMAA_024710	Uridine nucleosidase Urh1, putative. (370 aa)
	PMAA_034460	Epoxide hydrolase, putative. (342 aa)
	PMAA_026350	CBS and PB1 domain protein. (675 aa)
	PMAA_069360	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (209 aa)
	PMAA_071520	Inosine triphosphate pyrophosphatase, putative. (222 aa)
	PMAA_071690	Uridine kinase; Belongs to the uridine kinase family. (454 aa)
	PMAA_062720	5'-nucleotidase, putative; Belongs to the 5'-nucleotidase family. (749 aa)
	PMAA_072990	RED_N domain-containing protein. (593 aa)
	PMAA_063380	Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (470 aa)
	PMAA_073170	Ribonucleotide reductase small subunit RnrA, putative. (406 aa)
	PMAA_074670	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Belongs to the adenylosuccinate synthetase family. (422 aa)
	PMAA_074970	Amidohydrolase family protein. (476 aa)
	PMAA_065280	Adenosine deaminase, putative. (365 aa)
	PMAA_067820	Adenosine deaminase, putative. (373 aa)
	PMAA_087080	Uncharacterized protein. (128 aa)
	PMAA_077600	Adenosine deaminase, putative. (376 aa)
	PMAA_077860	CECR1 family adenosine deaminase, putative. (571 aa)
	PMAA_077930	NupC family nucleoside cotransporter. (605 aa)
	PMAA_089710	Uncharacterized protein. (307 aa)
	PMAA_080930	Phosphoribosylformylglycinamidine synthase. (1361 aa)
	PMAA_081020	Uncharacterized protein. (312 aa)
	PMAA_081620	HAD superfamily hydrolase, putative. (240 aa)
	PMAA_082170	Thymidylate kinase. (238 aa)
	PMAA_085800	Xanthine-guanine phosphoribosyl transferase Xpt1, putative. (204 aa)
	PMAA_086150	tRNA-specific adenosine deaminase subunit TAD2, putative. (190 aa)
	PMAA_086270	Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (179 aa)
	PMAA_086280	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (187 aa)
	PMAA_086380	Cytosine deaminase-uracil phosphoribosyltransferase fusion protein. (247 aa)
	PMAA_094220	Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (594 aa)
	ADK1	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (272 aa)
	PMAA_096280	tRNA-specific adenosine-34 deaminase subunit Tad3, putative. (512 aa)
	PMAA_098940	GMP synthase. (542 aa)
	PMAA_099480	Epoxide hydrolase, putative. (329 aa)
	PMAA_092050	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (482 aa)
	PMAA_102130	CMP/dCMP-type deaminase domain-containing protein. (217 aa)
	PMAA_054740	Adenylosuccinate lyase, putative. (503 aa)
	PMAA_056370	Phosphatidate cytidylyltransferase, putative. (957 aa)
	PMAA_060590	AMP deaminase Amd1, putative. (1061 aa)
	PMAA_051050	dUTPase (Dut), putative. (207 aa)
	PMAA_060730	Cytidine deaminase, putative. (420 aa)
	ADK2	GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (250 aa)
	PMAA_053750	Cytosine deaminase, putative. (148 aa)
	PMAA_047170	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (545 aa)
	PMAA_047880	Phosphoribosylglycinamide formyltransferase, putative. (224 aa)
	PMAA_046950	C6 transcription factor, putative. (695 aa)
	PMAA_049460	HD family hydrolase, putative. (220 aa)
	PMAA_040230	Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (573 aa)
	PMAA_040820	Xanthine dehydrogenase HxA, putative. (1359 aa)
	PMAA_041760	Phosphatidyl synthase. (498 aa)
	PMAA_044900	HAD superfamily hydrolase, putative. (405 aa)
	PMAA_045510	Uncharacterized protein. (450 aa)
	PMAA_043180	Nucleoside hydrolase, putative. (422 aa)
	PMAA_046160	Guanylate kinase. (200 aa)
	PMAA_001250	Zn(2)-C6 fungal-type domain-containing protein. (1184 aa)
	PMAA_001280	1-aminocyclopropane-1-carboxylate deaminase, putative. (347 aa)
	PMAA_004100	Phosphoribosyl-aminoimidazole-succinocarboxamide synthase. (302 aa)
	PMAA_003290	Dihydrofolate reductase. (326 aa)
	PMAA_004880	Uncharacterized protein. (713 aa)
	PMAA_005620	Ser/Thr protein phosphatase family. (611 aa)
	PMAA_005890	Chlorohydrolase family protein. (512 aa)
	PMAA_006560	IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation. (420 aa)
	PMAA_007000	Phosphatidyl synthase. (461 aa)
	PMAA_010820	Adenine phosphoribosyltransferase 1. (211 aa)
	PMAA_011320	Purine nucleoside phosphorylase I, inosine and guanosine-specific. (231 aa)
	PMAA_012300	Bifunctional purine biosynthetic protein Ade1, putative. (820 aa)
	PMAA_012960	Amidophosphoribosyltransferase. (544 aa)
	PMAA_014620	Arabinogalactan endo-beta-1,4-galactanase. (353 aa)

Your Current Organism:

Talaromyces marneffei

NCBI taxonomy Id: 441960
Other names: Penicillium marneffei ATCC 18224, T. marneffei ATCC 18224, Talaromyces marneffei ATCC 18224

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADK1	ADK2	B6QI08	B6QNP3	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	0.909
ADK1	PMAA_003290	B6QI08	B6QTC4	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Dihydrofolate reductase.	0.453
ADK1	PMAA_010820	B6QI08	B6QV11	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Adenine phosphoribosyltransferase 1.	0.974
ADK1	PMAA_011320	B6QI08	B6QV80	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Purine nucleoside phosphorylase I, inosine and guanosine-specific.	0.473
ADK1	PMAA_027600	B6QI08	B6Q240	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Uncharacterized protein.	0.696
ADK1	PMAA_027890	B6QI08	B6Q271	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.970
ADK1	PMAA_036930	B6QI08	B6Q1Q0	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Adenosine kinase, putative.	0.971
ADK1	PMAA_037950	B6QI08	B6Q2E0	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Urease accessory protein UreD.	0.407
ADK1	PMAA_046160	B6QI08	B6QRF0	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Guanylate kinase.	0.696
ADK1	PMAA_051050	B6QI08	B6QMN8	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	dUTPase (Dut), putative.	0.495
ADK1	PMAA_054740	B6QI08	B6QKQ0	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Adenylosuccinate lyase, putative.	0.658
ADK1	PMAA_060590	B6QI08	B6QMJ1	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	AMP deaminase Amd1, putative.	0.937
ADK1	PMAA_069360	B6QI08	B6Q8N9	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	0.532
ADK1	PMAA_073170	B6QI08	B6QAE5	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Ribonucleotide reductase small subunit RnrA, putative.	0.961
ADK1	PMAA_081020	B6QI08	B6QF54	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Uncharacterized protein.	0.564
ADK1	PMAA_082170	B6QI08	B6QFH6	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Thymidylate kinase.	0.564
ADK1	PMAA_085800	B6QI08	B6QGK2	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Xanthine-guanine phosphoribosyl transferase Xpt1, putative.	0.427
ADK1	PMAA_086270	B6QI08	B6QGQ4	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation.	0.930
ADK1	PMAA_092050	B6QI08	B6QK48	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.964
ADK1	PMAA_094220	B6QI08	B6QHG8	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.	0.617