88 items (Talaromyces marneffei) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PMAA_071470	Differentiation regulator (Nrd1), putative. (836 aa)
	PMAA_036890	RNA annealing protein Yra1, putative. (249 aa)
	PMAA_037180	THO complex component (Rlr1), putative. (2348 aa)
	PMAA_027650	Ribosome biogenesis (Nop4), putative. (728 aa)
	PMAA_037860	Decapping enzyme Dcp1, putative. (335 aa)
	PMAA_018270	mRNA binding protein Pumilio 2, putative. (929 aa)
	PMAA_018420	60S ribosomal protein L24a. (159 aa)
	PMAA_028640	Heterogeneous nuclear ribonucleoprotein HRP1. (454 aa)
	PMAA_029040	Polyadenylation factor subunit CstF64, putative. (290 aa)
	PMAA_019410	FHA domain protein SNIP1, putative. (327 aa)
	PMAA_029460	Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site; Belongs to the snRNP core protein family. (126 aa)
	PMAA_020170	Pre-RNA splicing factor Srp2, putative. (261 aa)
	PMAA_029960	U1 snRNP splicing complex subunit (Luc7), putative. (295 aa)
	PMAA_021170	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (381 aa)
	PMAA_030390	RNA binding effector protein Scp160, putative. (1297 aa)
	PMAA_021930	Polysaccharide export protein (CAP59), putative. (418 aa)
	PMAA_032560	Quinone oxidoreductase, putative. (334 aa)
	PMAA_023200	CFIA complex component Rna14, putative. (997 aa)
	CLU1	Clustered mitochondria protein homolog; mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. (1242 aa)
	PMAA_023720	Zinc knuckle transcription factor/splicing factor MSL5/ZFM1, putative. (565 aa)
	PMAA_024190	Ribosomal protein L16a; Belongs to the universal ribosomal protein uL13 family. (202 aa)
	PMAA_033920	U1 small nuclear ribonucleoprotein 70 kDa. (382 aa)
	PMAA_033990	NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (696 aa)
	PMAA_035250	KH domain protein. (1007 aa)
	PMAA_026340	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family. (119 aa)
	PMAA_036330	WD domain, G-beta repeat protein. (1548 aa)
	PMAA_069470	YT521-B-like splicing factor, putative. (683 aa)
	PMAA_069830	Uncharacterized protein. (320 aa)
	PMAA_071050	DUF2040 domain-containing protein. (467 aa)
	PMAA_071510	RNA binding protein Jsn1, putative. (1177 aa)
	PMAA_073450	Ribosome biogenesis protein Urb1, putative. (1128 aa)
	PMAA_073940	40S ribosomal protein S5, putative; Belongs to the universal ribosomal protein uS7 family. (213 aa)
	PMAA_064540	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (340 aa)
	PMAA_074850	Nuclear segregation protein (Bfr1), putative. (499 aa)
	PMAA_065250	Uncharacterized protein. (473 aa)
	PMAA_065980	RNA splicing factor (Pad-1), putative. (562 aa)
	PMAA_066430	Ribosome assembly protein Noc2, putative. (744 aa)
	PMAA_087220	PWI domain-containing protein. (753 aa)
	PMAA_087280	Uncharacterized protein. (307 aa)
	PMAA_087470	Eukaryotic translation initiation factor subunit eIF-4F, putative. (1504 aa)
	PMAA_079630	RNA binding protein. (591 aa)
	PMAA_080120	RNP domain protein. (434 aa)
	PMAA_080240	Quinone oxidoreductase, putative. (330 aa)
	PMAA_081580	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (198 aa)
	PMAA_083660	WD repeat protein. (298 aa)
	PMAA_083670	RNA binding protein, putative. (329 aa)
	PMAA_085650	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome. (1406 aa)
	PMAA_086490	Peptide chain release factor eRF/aRF, subunit 1. (447 aa)
	PMAA_095200	RNA-binding protein, putative. (1026 aa)
	PMAA_095580	Pumilio-family RNA binding repeat domain protein. (768 aa)
	PMAA_095980	Zinc knuckle domain protein (Byr3), putative. (183 aa)
	PMAA_096160	mRNA cleavage factor complex component Pcf11, putative. (639 aa)
	PMAA_096400	50S ribosomal protein L12. (197 aa)
	PMAA_096420	Uncharacterized protein. (455 aa)
	PMAA_098010	Nuclear and cytoplasmic polyadenylated RNA-binding protein pub1. (482 aa)
	PMAA_098330	G2/M phase checkpoint control protein Sum2, putative. (558 aa)
	PMAA_100240	Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7- methylguanosine cap of a subset of mRNAs. (586 aa)
	PMAA_091950	Pre-rRNA processing protein Rrp12, putative. (1273 aa)
	PMAA_054630	30S ribosomal protein S7, putative. (364 aa)
	PMAA_055960	RNA binding protein (Rbm8A), putative. (157 aa)
	PMAA_057060	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1021 aa)
	PMAA_057960	mRNA splicing factor (Prp17), putative. (576 aa)
	PMAA_058060	Uncharacterized protein. (241 aa)
	PMAA_051000	Uncharacterized protein. (463 aa)
	PMAA_051270	RNA binding protein. (487 aa)
	PMAA_051970	NTF2 and RRM domain protein. (549 aa)
	PMAA_052230	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (556 aa)
	PMAA_052390	Splicing factor 3B subunit 1, putative. (1221 aa)
	PMAA_053150	Nonsense-mediated mRNA decay protein Upf3, putative. (570 aa)
	PMAA_053810	SAM domain protein. (614 aa)
	PMAA_047920	RNA helicase (Dbp), putative; Belongs to the DEAD box helicase family. (554 aa)
	PMAA_047680	50S ribosomal protein L13. (175 aa)
	PMAA_047730	40S ribosomal protein S11; Belongs to the universal ribosomal protein uS11 family. (151 aa)
	PMAA_039640	R3H domain protein, putative. (594 aa)
	PMAA_039710	Cleavage and polyadenylation specific factor 5. (282 aa)
	PMAA_040890	Uncharacterized protein. (324 aa)
	PMAA_046400	Proteasome subunit alpha type. (292 aa)
	PMAA_043940	PUM-HD domain-containing protein. (703 aa)
	PMAA_044440	37S ribosomal protein S11, putative. (241 aa)
	PMAA_043860	60S ribosomal protein L35. (125 aa)
	PMAA_004160	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (687 aa)
	PMAA_005210	DEAD-box RNA helicase Dhh1/Vad1, putative; Belongs to the DEAD box helicase family. (498 aa)
	PMAA_010670	mRNA binding post-transcriptional regulator (Csx1), putative. (392 aa)
	PMAA_010720	Zinc knuckle nucleic acid binding protein, putative. (246 aa)
	PMAA_011520	snRNA cap binding complex subunit (Gcr3), putative. (853 aa)
	PMAA_012140	Uncharacterized protein. (184 aa)
	PMAA_013000	Translational initiation factor 2 beta. (307 aa)
	PMAA_013960	Nucleolin protein Nsr1, putative. (472 aa)

Your Current Organism:

Talaromyces marneffei

NCBI taxonomy Id: 441960
Other names: Penicillium marneffei ATCC 18224, T. marneffei ATCC 18224, Talaromyces marneffei ATCC 18224

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLU1	PMAA_051970	B6Q5T2	B6QN47	Clustered mitochondria protein homolog; mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.	NTF2 and RRM domain protein.	0.434
PMAA_005210	PMAA_011520	B6QTJ3	B6QVA1	DEAD-box RNA helicase Dhh1/Vad1, putative; Belongs to the DEAD box helicase family.	snRNA cap binding complex subunit (Gcr3), putative.	0.421
PMAA_005210	PMAA_018270	B6QTJ3	B6Q2G1	DEAD-box RNA helicase Dhh1/Vad1, putative; Belongs to the DEAD box helicase family.	mRNA binding protein Pumilio 2, putative.	0.647
PMAA_005210	PMAA_021930	B6QTJ3	B6Q4W3	DEAD-box RNA helicase Dhh1/Vad1, putative; Belongs to the DEAD box helicase family.	Polysaccharide export protein (CAP59), putative.	0.506
PMAA_005210	PMAA_029460	B6QTJ3	B6Q3N9	DEAD-box RNA helicase Dhh1/Vad1, putative; Belongs to the DEAD box helicase family.	Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site; Belongs to the snRNP core protein family.	0.440
PMAA_005210	PMAA_030390	B6QTJ3	B6Q4B6	DEAD-box RNA helicase Dhh1/Vad1, putative; Belongs to the DEAD box helicase family.	RNA binding effector protein Scp160, putative.	0.532
PMAA_005210	PMAA_033990	B6QTJ3	B6Q6C1	DEAD-box RNA helicase Dhh1/Vad1, putative; Belongs to the DEAD box helicase family.	NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.	0.999
PMAA_005210	PMAA_035250	B6QTJ3	B6Q765	DEAD-box RNA helicase Dhh1/Vad1, putative; Belongs to the DEAD box helicase family.	KH domain protein.	0.415
PMAA_005210	PMAA_036890	B6QTJ3	B6Q1P6	DEAD-box RNA helicase Dhh1/Vad1, putative; Belongs to the DEAD box helicase family.	RNA annealing protein Yra1, putative.	0.442
PMAA_005210	PMAA_037860	B6QTJ3	B6Q2D2	DEAD-box RNA helicase Dhh1/Vad1, putative; Belongs to the DEAD box helicase family.	Decapping enzyme Dcp1, putative.	0.997
PMAA_005210	PMAA_051270	B6QTJ3	B6QMR0	DEAD-box RNA helicase Dhh1/Vad1, putative; Belongs to the DEAD box helicase family.	RNA binding protein.	0.496
PMAA_005210	PMAA_051970	B6QTJ3	B6QN47	DEAD-box RNA helicase Dhh1/Vad1, putative; Belongs to the DEAD box helicase family.	NTF2 and RRM domain protein.	0.456
PMAA_005210	PMAA_052390	B6QTJ3	B6QNE3	DEAD-box RNA helicase Dhh1/Vad1, putative; Belongs to the DEAD box helicase family.	Splicing factor 3B subunit 1, putative.	0.512
PMAA_005210	PMAA_053150	B6QTJ3	B6QNL8	DEAD-box RNA helicase Dhh1/Vad1, putative; Belongs to the DEAD box helicase family.	Nonsense-mediated mRNA decay protein Upf3, putative.	0.615
PMAA_005210	PMAA_055960	B6QTJ3	B6QL27	DEAD-box RNA helicase Dhh1/Vad1, putative; Belongs to the DEAD box helicase family.	RNA binding protein (Rbm8A), putative.	0.479
PMAA_005210	PMAA_083670	B6QTJ3	B6QFX8	DEAD-box RNA helicase Dhh1/Vad1, putative; Belongs to the DEAD box helicase family.	RNA binding protein, putative.	0.442
PMAA_005210	PMAA_087470	B6QTJ3	B6QDE1	DEAD-box RNA helicase Dhh1/Vad1, putative; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor subunit eIF-4F, putative.	0.506
PMAA_005210	PMAA_095200	B6QTJ3	B6QHS0	DEAD-box RNA helicase Dhh1/Vad1, putative; Belongs to the DEAD box helicase family.	RNA-binding protein, putative.	0.543
PMAA_005210	PMAA_095580	B6QTJ3	B6QHV9	DEAD-box RNA helicase Dhh1/Vad1, putative; Belongs to the DEAD box helicase family.	Pumilio-family RNA binding repeat domain protein.	0.460
PMAA_005210	PMAA_098010	B6QTJ3	B6QIL7	DEAD-box RNA helicase Dhh1/Vad1, putative; Belongs to the DEAD box helicase family.	Nuclear and cytoplasmic polyadenylated RNA-binding protein pub1.	0.507