32 items (Talaromyces marneffei) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Your Input:
	PMAA_077390	Iso_dh domain-containing protein. (106 aa)
	PMAA_017460	Citrate synthase; Belongs to the citrate synthase family. (467 aa)
	PMAA_018400	Fumarate hydratase, putative. (531 aa)
	PMAA_021040	Malate synthase; Belongs to the malate synthase family. (539 aa)
	PMAA_026060	Haloacid dehalogenase, type II. (238 aa)
	PMAA_016540	GFA domain-containing protein. (172 aa)
	PMAA_026400	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (792 aa)
	PMAA_065730	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit. (179 aa)
	PMAA_068140	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (386 aa)
	PMAA_077400	Iso_dh domain-containing protein. (177 aa)
	PMAA_079040	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (785 aa)
	PMAA_089220	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (297 aa)
	PMAA_080470	Isocitrate lyase. (540 aa)
	PMAA_083110	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (616 aa)
	PMAA_083220	Succinate dehydrogenase cytochrome b560 subunit. (186 aa)
	PMAA_084950	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (330 aa)
	PMAA_085820	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (444 aa)
	PMAA_095310	Citrate synthase; Belongs to the citrate synthase family. (472 aa)
	PMAA_096660	Uncharacterized protein. (442 aa)
	PMAA_091390	Citrate synthase; Belongs to the citrate synthase family. (463 aa)
	PMAA_091680	Malate dehydrogenase. (340 aa)
	PMAA_057560	Isochorismatase domain-containing protein. (190 aa)
	PMAA_060670	Tartrate dehydrogenase, putative. (369 aa)
	PMAA_049320	Succinate dehydrogenase, putative. (200 aa)
	PMAA_041660	Alpha-ketoglutarate dehydrogenase complex subunit Kgd1, putative. (1063 aa)
	PMAA_042540	Succinyl-CoA synthetase subunit alpha, putative. (676 aa)
	PMAA_046420	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (384 aa)
	PMAA_004900	Uncharacterized protein. (374 aa)
	PMAA_005300	Dihydrolipoamide succinyltransferase, putative. (476 aa)
	PMAA_011500	Malate dehydrogenase. (331 aa)
	PMAA_012920	Isocitrate dehydrogenase Idp1, putative. (820 aa)
	PMAA_013370	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (647 aa)

Your Current Organism:

Talaromyces marneffei

NCBI taxonomy Id: 441960
Other names: Penicillium marneffei ATCC 18224, T. marneffei ATCC 18224, Talaromyces marneffei ATCC 18224

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PMAA_004900	PMAA_005300	B6QTK0	B6QTM2	Uncharacterized protein.	Dihydrolipoamide succinyltransferase, putative.	0.616
PMAA_004900	PMAA_011500	B6QTK0	B6QV95	Uncharacterized protein.	Malate dehydrogenase.	0.725
PMAA_004900	PMAA_013370	B6QTK0	B6QVW0	Uncharacterized protein.	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.525
PMAA_004900	PMAA_017460	B6QTK0	B6Q1G9	Uncharacterized protein.	Citrate synthase; Belongs to the citrate synthase family.	0.706
PMAA_004900	PMAA_018400	B6QTK0	B6Q2H4	Uncharacterized protein.	Fumarate hydratase, putative.	0.563
PMAA_004900	PMAA_021040	B6QTK0	B6Q490	Uncharacterized protein.	Malate synthase; Belongs to the malate synthase family.	0.598
PMAA_004900	PMAA_026400	B6QTK0	B6Q829	Uncharacterized protein.	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	0.778
PMAA_004900	PMAA_041660	B6QTK0	B6QQB9	Uncharacterized protein.	Alpha-ketoglutarate dehydrogenase complex subunit Kgd1, putative.	0.841
PMAA_004900	PMAA_042540	B6QTK0	B6QQM4	Uncharacterized protein.	Succinyl-CoA synthetase subunit alpha, putative.	0.569
PMAA_004900	PMAA_046420	B6QTK0	B6QRH0	Uncharacterized protein.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.702
PMAA_004900	PMAA_057560	B6QTK0	B6QLJ5	Uncharacterized protein.	Isochorismatase domain-containing protein.	0.598
PMAA_004900	PMAA_068140	B6QTK0	B6QCR4	Uncharacterized protein.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.582
PMAA_004900	PMAA_077400	B6QTK0	B6QD57	Uncharacterized protein.	Iso_dh domain-containing protein.	0.443
PMAA_004900	PMAA_079040	B6QTK0	B6QE06	Uncharacterized protein.	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	0.784
PMAA_004900	PMAA_080470	B6QTK0	B6QEU2	Uncharacterized protein.	Isocitrate lyase.	0.518
PMAA_004900	PMAA_083110	B6QTK0	B6QFS1	Uncharacterized protein.	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.525
PMAA_004900	PMAA_084950	B6QTK0	B6QGB0	Uncharacterized protein.	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.603
PMAA_004900	PMAA_085820	B6QTK0	B6QGK4	Uncharacterized protein.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.647
PMAA_004900	PMAA_089220	B6QTK0	B6QEH7	Uncharacterized protein.	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.684
PMAA_004900	PMAA_091390	B6QTK0	B6QJR5	Uncharacterized protein.	Citrate synthase; Belongs to the citrate synthase family.	0.706