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PMAA_066380 PMAA_066380 PMAA_065280 PMAA_065280 PMAA_075950 PMAA_075950 PMAA_076220 PMAA_076220 PMAA_066820 PMAA_066820 PMAA_067820 PMAA_067820 PMAA_087050 PMAA_087050 PMAA_087230 PMAA_087230 PMAA_077600 PMAA_077600 PMAA_077860 PMAA_077860 PMAA_087670 PMAA_087670 PMAA_089120 PMAA_089120 PMAA_089130 PMAA_089130 PMAA_089440 PMAA_089440 PMAA_080930 PMAA_080930 PMAA_081280 PMAA_081280 PMAA_082210 PMAA_082210 PMAA_083570 PMAA_083570 PMAA_085290 PMAA_085290 PMAA_085660 PMAA_085660 PMAA_085800 PMAA_085800 PMAA_085820 PMAA_085820 PMAA_m0570 PMAA_m0570 PMAA_m0100 PMAA_m0100 PMAA_m0090 PMAA_m0090 PMAA_014930 PMAA_014930 PMAA_013700 PMAA_013700 PMAA_013410 PMAA_013410 PMAA_012960 PMAA_012960 PMAA_012300 PMAA_012300 PMAA_011320 PMAA_011320 PMAA_010820 PMAA_010820 PMAA_009290 PMAA_009290 PMAA_009300 PMAA_009300 PMAA_009200 PMAA_009200 PMAA_009190 PMAA_009190 PMAA_006650 PMAA_006650 PMAA_006560 PMAA_006560 PMAA_005890 PMAA_005890 PMAA_005750 PMAA_005750 PMAA_005610 PMAA_005610 PMAA_005300 PMAA_005300 PMAA_004880 PMAA_004880 PMAA_004100 PMAA_004100 PMAA_004230 PMAA_004230 PMAA_002430 PMAA_002430 PMAA_002180 PMAA_002180 PMAA_001250 PMAA_001250 PMAA_044020 PMAA_044020 PMAA_048220 PMAA_048220 PMAA_046160 PMAA_046160 PMAA_043370 PMAA_043370 PMAA_043180 PMAA_043180 PMAA_045430 PMAA_045430 PMAA_045270 PMAA_045270 PMAA_045240 PMAA_045240 PMAA_041020 PMAA_041020 PMAA_040820 PMAA_040820 PMAA_040720 PMAA_040720 PMAA_039740 PMAA_039740 PMAA_039680 PMAA_039680 PMAA_040230 PMAA_040230 PMAA_047670 PMAA_047670 PMAA_046950 PMAA_046950 PMAA_047880 PMAA_047880 PMAA_047290 PMAA_047290 PMAA_047170 PMAA_047170 PMAA_049910 PMAA_049910 PMAA_053470 PMAA_053470 ADK2 ADK2 PMAA_052560 PMAA_052560 PMAA_051020 PMAA_051020 PMAA_050880 PMAA_050880 PMAA_050780 PMAA_050780 PMAA_060590 PMAA_060590 PMAA_059790 PMAA_059790 PMAA_057700 PMAA_057700 PMAA_057560 PMAA_057560 PMAA_057300 PMAA_057300 PMAA_057020 PMAA_057020 PMAA_054740 PMAA_054740 PMAA_092050 PMAA_092050 PMAA_091620 PMAA_091620 PMAA_091590 PMAA_091590 PMAA_098940 PMAA_098940 PMAA_098390 PMAA_098390 PMAA_098240 PMAA_098240 PMAA_097800 PMAA_097800 PMAA_097760 PMAA_097760 PMAA_097360 PMAA_097360 PMAA_096660 PMAA_096660 PMAA_096370 PMAA_096370 ADK1 ADK1 PMAA_094340 PMAA_094340 PMAA_094220 PMAA_094220 PMAA_093840 PMAA_093840 PMAA_092490 PMAA_092490 PMAA_017140 PMAA_017140 PMAA_017210 PMAA_017210 PMAA_027160 PMAA_027160 PMAA_027260 PMAA_027260 PMAA_036930 PMAA_036930 PMAA_017650 PMAA_017650 PMAA_017820 PMAA_017820 PMAA_027600 PMAA_027600 PMAA_018550 PMAA_018550 PMAA_018620 PMAA_018620 PMAA_019200 PMAA_019200 PMAA_028880 PMAA_028880 PMAA_019740 PMAA_019740 AAH1 AAH1 PMAA_020100 PMAA_020100 PMAA_030060 PMAA_030060 PMAA_021180 PMAA_021180 PMAA_022720 PMAA_022720 PMAA_022780 PMAA_022780 PMAA_023750 PMAA_023750 PMAA_033950 PMAA_033950 PMAA_034120 PMAA_034120 PMAA_024700 PMAA_024700 PMAA_024710 PMAA_024710 PMAA_035670 PMAA_035670 PMAA_026490 PMAA_026490 PMAA_036560 PMAA_036560 PMAA_068940 PMAA_068940 PMAA_070150 PMAA_070150 PMAA_070980 PMAA_070980 PMAA_071620 PMAA_071620 PMAA_071870 PMAA_071870 PMAA_062410 PMAA_062410 PMAA_072020 PMAA_072020 PMAA_072120 PMAA_072120 PMAA_062720 PMAA_062720 PMAA_072990 PMAA_072990 PMAA_063380 PMAA_063380 PMAA_073330 PMAA_073330 PMAA_073580 PMAA_073580 PMAA_064290 PMAA_064290 PMAA_074140 PMAA_074140 PMAA_064540 PMAA_064540 PMAA_074650 PMAA_074650 PMAA_074670 PMAA_074670 PMAA_074970 PMAA_074970
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PMAA_066380Mitochondrial F1F0-ATP synthase g subunit, putative. (198 aa)
PMAA_065280Adenosine deaminase, putative. (365 aa)
PMAA_075950Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (507 aa)
PMAA_076220Nudix/MutT family protein. (159 aa)
PMAA_066820Phosphotransferase. (553 aa)
PMAA_067820Adenosine deaminase, putative. (373 aa)
PMAA_087050Fatty acid activator Faa4, putative. (755 aa)
PMAA_087230Glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
PMAA_077600Adenosine deaminase, putative. (376 aa)
PMAA_077860CECR1 family adenosine deaminase, putative. (571 aa)
PMAA_087670Phosphoglucomutase, putative. (609 aa)
PMAA_089120Oxidoreductase, putative. (440 aa)
PMAA_089130Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (289 aa)
PMAA_089440Phosphoserine aminotransferase. (423 aa)
PMAA_080930Phosphoribosylformylglycinamidine synthase. (1361 aa)
PMAA_081280Vacuolar ATP synthase catalytic subunit A, putative. (715 aa)
PMAA_082210Nucleoside diphosphate kinase. (153 aa)
PMAA_083570Cobalamin-independent methionine synthase MetH/D. (765 aa)
PMAA_085290Uncharacterized protein. (72 aa)
PMAA_085660PaaI_thioesterase family protein, putative. (159 aa)
PMAA_085800Xanthine-guanine phosphoribosyl transferase Xpt1, putative. (204 aa)
PMAA_085820Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (444 aa)
PMAA_m0570ATP synthase subunit 9, mitochondrial; Belongs to the ATPase C chain family. (74 aa)
PMAA_m0100ATP synthase subunit a. (256 aa)
PMAA_m0090ATP synthase subunit 8. (48 aa)
PMAA_014930TauD domain-containing protein. (369 aa)
PMAA_013700Pyruvate dehydrogenase complex component Pdx1, putative. (296 aa)
PMAA_013410Uncharacterized protein. (411 aa)
PMAA_012960Amidophosphoribosyltransferase. (544 aa)
PMAA_012300Bifunctional purine biosynthetic protein Ade1, putative. (820 aa)
PMAA_011320Purine nucleoside phosphorylase I, inosine and guanosine-specific. (231 aa)
PMAA_010820Adenine phosphoribosyltransferase 1. (211 aa)
PMAA_009290Methylenetetrahydrofolate dehydrogenase. (322 aa)
PMAA_009300ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (555 aa)
PMAA_009200Mitochondrial ATPase subunit ATP4, putative. (242 aa)
PMAA_009190Uncharacterized protein. (396 aa)
PMAA_006650ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (804 aa)
PMAA_006560IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation. (420 aa)
PMAA_005890Chlorohydrolase family protein. (512 aa)
PMAA_005750Phosphotransferase. (603 aa)
PMAA_005610Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (376 aa)
PMAA_005300Dihydrolipoamide succinyltransferase, putative. (476 aa)
PMAA_004880Uncharacterized protein. (713 aa)
PMAA_004100Phosphoribosyl-aminoimidazole-succinocarboxamide synthase. (302 aa)
PMAA_004230Glutaryl-CoA dehydrogenase, putative. (426 aa)
PMAA_002430Pantothenate kinase, putative. (450 aa)
PMAA_002180Phosphopantothenate-cysteine ligase, putative. (402 aa)
PMAA_001250Zn(2)-C6 fungal-type domain-containing protein. (1184 aa)
PMAA_044020Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (417 aa)
PMAA_048220Triosephosphate isomerase. (291 aa)
PMAA_046160Guanylate kinase. (200 aa)
PMAA_043370NMT1 domain-containing protein. (303 aa)
PMAA_043180Nucleoside hydrolase, putative. (422 aa)
PMAA_045430Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent. (520 aa)
PMAA_045270Allantoinase Dal1, putative. (531 aa)
PMAA_045240Mitochondrial F1F0 ATP synthase subunit Atp18, putative. (60 aa)
PMAA_041020Acetyl-coenzyme A synthetase. (668 aa)
PMAA_040820Xanthine dehydrogenase HxA, putative. (1359 aa)
PMAA_040720Phosphoribosyl diphosphate synthase isoform 4. (320 aa)
PMAA_039740Dephospho-CoA kinase, putative. (275 aa)
PMAA_039680Glyceraldehyde-3-phosphate dehydrogenase. (337 aa)
PMAA_040230Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (573 aa)
PMAA_047670Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family. (302 aa)
PMAA_046950C6 transcription factor, putative. (695 aa)
PMAA_047880Phosphoribosylglycinamide formyltransferase, putative. (224 aa)
PMAA_0472903-hydroxy-3-methylglutaryl coenzyme A reductase. (1127 aa)
PMAA_047170Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (545 aa)
PMAA_049910TauD domain-containing protein. (468 aa)
PMAA_053470ATP synthase subunit gamma. (298 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (250 aa)
PMAA_0525603-hydroxyisobutyrate dehydrogenase. (342 aa)
PMAA_051020ATP synthase delta chain, mitochondrial, putative. (190 aa)
PMAA_050880NUDIX domain, putative; Belongs to the Nudix hydrolase family. (163 aa)
PMAA_050780Ribose-phosphate pyrophosphokinase 1, putative. (323 aa)
PMAA_060590AMP deaminase Amd1, putative. (1061 aa)
PMAA_059790Uncharacterized protein. (90 aa)
PMAA_057700Pyruvate kinase; Belongs to the pyruvate kinase family. (525 aa)
PMAA_057560Isochorismatase domain-containing protein. (190 aa)
PMAA_057300ATP synthase subunit ATP9, putative; Belongs to the ATPase C chain family. (148 aa)
PMAA_057020Pantetheine-phosphate adenylyltransferase family protein. (391 aa)
PMAA_054740Adenylosuccinate lyase, putative. (503 aa)
PMAA_092050Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (482 aa)
PMAA_091620Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (472 aa)
PMAA_091590Ribose phosphate diphosphokinase Prs1, putative. (477 aa)
PMAA_098940GMP synthase. (542 aa)
PMAA_098390ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (519 aa)
PMAA_098240Mitochondrial ATP synthase epsilon chain domain-containing protein. (73 aa)
PMAA_0978003-hydroxyisobutyrate dehydrogenase, putative. (334 aa)
PMAA_0977603-hydroxyisobutyrate dehydrogenase, putative. (333 aa)
PMAA_097360NUDIX family hydrolase, putative. (429 aa)
PMAA_096660Uncharacterized protein. (442 aa)
PMAA_096370Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (407 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (272 aa)
PMAA_094340Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (558 aa)
PMAA_094220Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (594 aa)
PMAA_093840Enolase/allergen Asp F 22. (438 aa)
PMAA_092490ATP synthase oligomycin sensitivity conferral protein, putative. (227 aa)
PMAA_017140Mitochondrial F1F0 ATP synthase subunit Atp14, putative. (124 aa)
PMAA_0172103-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (457 aa)
PMAA_027160Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (402 aa)
PMAA_027260Acyl-CoA thioester hydrolase, putative. (471 aa)
PMAA_036930Adenosine kinase, putative. (349 aa)
PMAA_017650ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (174 aa)
PMAA_017820Phosphotransferase. (501 aa)
PMAA_027600Uncharacterized protein. (255 aa)
PMAA_018550Flavoprotein, putative. (243 aa)
PMAA_018620Phosphotransferase. (495 aa)
PMAA_019200Transthyretin domain protein. (173 aa)
PMAA_028880Phosphotransferase. (490 aa)
PMAA_019740Ribose-phosphate pyrophosphokinase. (434 aa)
AAH1Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (352 aa)
PMAA_020100EAF domain-containing protein. (424 aa)
PMAA_030060Flavoprotein domain-containing protein. (631 aa)
PMAA_021180Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (360 aa)
PMAA_022720Allantoicase Alc, putative. (379 aa)
PMAA_022780C6 finger domain protein Acr-2, putative. (557 aa)
PMAA_023750Probable acetate kinase. (452 aa)
PMAA_033950Triosephosphate isomerase. (249 aa)
PMAA_034120DUF614 domain protein. (235 aa)
PMAA_024700Uncharacterized protein. (627 aa)
PMAA_024710Uridine nucleosidase Urh1, putative. (370 aa)
PMAA_035670ATP citrate lyase subunit (Acl), putative. (484 aa)
PMAA_0264903-hydroxyisobutyrate dehydrogenase, putative. (318 aa)
PMAA_036560Phosphotransferase. (626 aa)
PMAA_068940Phosphotransferase. (543 aa)
PMAA_070150Acyl-CoA synthetase, putative. (708 aa)
PMAA_070980Acetyl-CoA carboxylase, putative. (2294 aa)
PMAA_071620Mitochondrial F1F0 ATP synthase subunit F (Atp17), putative. (102 aa)
PMAA_071870Adenylate cyclase AcyA. (2152 aa)
PMAA_062410Zn(2)-C6 fungal-type domain-containing protein. (629 aa)
PMAA_072020GTP binding protein (GTPBP1), putative. (651 aa)
PMAA_072120OHCU_decarbox domain-containing protein. (192 aa)
PMAA_0627205'-nucleotidase, putative; Belongs to the 5'-nucleotidase family. (749 aa)
PMAA_072990RED_N domain-containing protein. (593 aa)
PMAA_063380Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (470 aa)
PMAA_073330Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (487 aa)
PMAA_073580Histidine acid phosphatase, putative; Belongs to the histidine acid phosphatase family. (1013 aa)
PMAA_064290Pyruvate dehydrogenase, putative. (406 aa)
PMAA_074140cAMP-specific phosphodiesterase, putative. (554 aa)
PMAA_064540S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (340 aa)
PMAA_074650C6 transcription factor (UaY), putative. (999 aa)
PMAA_074670Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Belongs to the adenylosuccinate synthetase family. (422 aa)
PMAA_074970Amidohydrolase family protein. (476 aa)
Your Current Organism:
Talaromyces marneffei
NCBI taxonomy Id: 441960
Other names: Penicillium marneffei ATCC 18224, T. marneffei ATCC 18224, Talaromyces marneffei ATCC 18224
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