(12 nodes) Aminoacid dehydrogenase-like, N-terminal domain superfamily network (Talaromyces marneffei)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	PMAA_028760	Shikimate 5-dehydrogenase, putative. (312 aa)
	PMAA_038680	Pentafunctional AROM polypeptide, putative. (824 aa)
	PMAA_070640	Malic enzyme. (660 aa)
	aroM-2	3-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family. (1571 aa)
	PMAA_060810	Repressor protein. (821 aa)
	PMAA_009290	Methylenetetrahydrofolate dehydrogenase. (322 aa)
	PMAA_011020	Malic enzyme. (577 aa)
	PMAA_012930	C1 tetrahydrofolate synthase, putative. (939 aa)
	aroM-1	3-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family. (1573 aa)
	PMAA_027850	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (466 aa)
	PMAA_038650	Quinate 5-dehydrogenase QutB, putative. (346 aa)
	PMAA_028730	NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (1137 aa)

Your Current Organism:

Talaromyces marneffei

NCBI taxonomy Id: 441960
Other names: Penicillium marneffei ATCC 18224, T. marneffei ATCC 18224, Talaromyces marneffei ATCC 18224

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PMAA_009290	PMAA_012930	B6QUJ8	B6QVL9	Methylenetetrahydrofolate dehydrogenase.	C1 tetrahydrofolate synthase, putative.	0.990
PMAA_009290	PMAA_027850	B6QUJ8	B6Q267	Methylenetetrahydrofolate dehydrogenase.	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.427
PMAA_009290	PMAA_028730	B6QUJ8	B6Q389	Methylenetetrahydrofolate dehydrogenase.	NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.427
PMAA_011020	PMAA_070640	B6QV32	B6Q924	Malic enzyme.	Malic enzyme.	0.907
PMAA_012930	PMAA_009290	B6QVL9	B6QUJ8	C1 tetrahydrofolate synthase, putative.	Methylenetetrahydrofolate dehydrogenase.	0.990
PMAA_012930	PMAA_027850	B6QVL9	B6Q267	C1 tetrahydrofolate synthase, putative.	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.433
PMAA_012930	PMAA_028730	B6QVL9	B6Q389	C1 tetrahydrofolate synthase, putative.	NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.433
PMAA_027850	PMAA_009290	B6Q267	B6QUJ8	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Methylenetetrahydrofolate dehydrogenase.	0.427
PMAA_027850	PMAA_012930	B6Q267	B6QVL9	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	C1 tetrahydrofolate synthase, putative.	0.433
PMAA_027850	PMAA_028730	B6Q267	B6Q389	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.959
PMAA_028730	PMAA_009290	B6Q389	B6QUJ8	NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Methylenetetrahydrofolate dehydrogenase.	0.427
PMAA_028730	PMAA_012930	B6Q389	B6QVL9	NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	C1 tetrahydrofolate synthase, putative.	0.433
PMAA_028730	PMAA_027850	B6Q389	B6Q267	NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.959
PMAA_028760	PMAA_038650	B6Q393	B6Q2Y5	Shikimate 5-dehydrogenase, putative.	Quinate 5-dehydrogenase QutB, putative.	0.916
PMAA_028760	aroM-1	B6Q393	B6QWH9	Shikimate 5-dehydrogenase, putative.	3-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family.	0.900
PMAA_028760	aroM-2	B6Q393	B6QCA7	Shikimate 5-dehydrogenase, putative.	3-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family.	0.900
PMAA_038650	PMAA_028760	B6Q2Y5	B6Q393	Quinate 5-dehydrogenase QutB, putative.	Shikimate 5-dehydrogenase, putative.	0.916
PMAA_038650	aroM-1	B6Q2Y5	B6QWH9	Quinate 5-dehydrogenase QutB, putative.	3-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family.	0.907
PMAA_038650	aroM-2	B6Q2Y5	B6QCA7	Quinate 5-dehydrogenase QutB, putative.	3-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family.	0.907
PMAA_070640	PMAA_011020	B6Q924	B6QV32	Malic enzyme.	Malic enzyme.	0.907