23 items (Talaromyces marneffei) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

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co-expression

protein homology

Your Input:
	PMAA_026300	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (563 aa)
	PMAA_070480	Tubulin-specific chaperone A; Belongs to the TBCA family. (120 aa)
	PMAA_086450	Translocase of inner mitochondrial membrane, putative; Belongs to the small Tim family. (91 aa)
	PMAA_051840	COX assembly mitochondrial protein; Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration; Belongs to the CMC family. (88 aa)
	MZM1	Mitochondrial zinc maintenance protein 1, mitochondrial; Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane. Modulates the mitochondrial matrix zinc pool (By similarity). (113 aa)
	PMAA_013390	T-complex protein 1 subunit delta. (536 aa)
	PMAA_073650	Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family. (137 aa)
	PMAA_096390	T-complex protein 1, theta subunit, putative. (581 aa)
	PMAA_045290	Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (206 aa)
	PMAA_042900	Heat shock protein/chaperonin HSP78, putative; Belongs to the ClpA/ClpB family. (787 aa)
	PMAA_084190	T-complex protein 1, alpha subunit, putative. (567 aa)
	PMAA_076280	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (247 aa)
	PMAA_092250	Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (4898 aa)
	PMAA_092290	Mitochondrial intermembrane space translocase subunit Tim13, putative; Belongs to the small Tim family. (112 aa)
	PMAA_039950	Calnexin. (563 aa)
	PMAA_046000	T-complex protein 1, zeta subunit, putative. (541 aa)
	PMAA_087570	T-complex protein 1, beta subunit, putative. (528 aa)
	PMAA_081900	Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer. (267 aa)
	PMAA_073680	Heat shock protein Hsp98/Hsp104/ClpA, putative; Belongs to the ClpA/ClpB family. (928 aa)
	PMAA_074430	COX assembly mitochondrial protein; Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration; Belongs to the CMC family. (130 aa)
	PMAA_032190	T-complex protein 1, epsilon subunit, putative. (548 aa)
	PMAA_023030	T-complex protein 1 subunit gamma. (539 aa)
	PMAA_035550	Chaperonin, putative; Belongs to the GroES chaperonin family. (102 aa)

Your Current Organism:

Talaromyces marneffei

NCBI taxonomy Id: 441960
Other names: Penicillium marneffei ATCC 18224, T. marneffei ATCC 18224, Talaromyces marneffei ATCC 18224

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PMAA_013390	PMAA_023030	B6QVW3	B6Q5F2	T-complex protein 1 subunit delta.	T-complex protein 1 subunit gamma.	0.999
PMAA_013390	PMAA_026300	B6QVW3	B6Q818	T-complex protein 1 subunit delta.	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.	0.999
PMAA_013390	PMAA_032190	B6QVW3	B6Q587	T-complex protein 1 subunit delta.	T-complex protein 1, epsilon subunit, putative.	0.999
PMAA_013390	PMAA_035550	B6QVW3	B6Q7M7	T-complex protein 1 subunit delta.	Chaperonin, putative; Belongs to the GroES chaperonin family.	0.827
PMAA_013390	PMAA_042900	B6QVW3	B6QR47	T-complex protein 1 subunit delta.	Heat shock protein/chaperonin HSP78, putative; Belongs to the ClpA/ClpB family.	0.475
PMAA_013390	PMAA_045290	B6QVW3	B6QQT5	T-complex protein 1 subunit delta.	Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family.	0.689
PMAA_013390	PMAA_046000	B6QVW3	B6QRD1	T-complex protein 1 subunit delta.	T-complex protein 1, zeta subunit, putative.	0.999
PMAA_013390	PMAA_070480	B6QVW3	B6Q907	T-complex protein 1 subunit delta.	Tubulin-specific chaperone A; Belongs to the TBCA family.	0.450
PMAA_013390	PMAA_073650	B6QVW3	B6QAJ3	T-complex protein 1 subunit delta.	Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family.	0.821
PMAA_013390	PMAA_073680	B6QVW3	B6QAJ6	T-complex protein 1 subunit delta.	Heat shock protein Hsp98/Hsp104/ClpA, putative; Belongs to the ClpA/ClpB family.	0.475
PMAA_013390	PMAA_076280	B6QVW3	B6QC40	T-complex protein 1 subunit delta.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.732
PMAA_013390	PMAA_084190	B6QVW3	B6QG28	T-complex protein 1 subunit delta.	T-complex protein 1, alpha subunit, putative.	0.999
PMAA_013390	PMAA_087570	B6QVW3	B6QDF1	T-complex protein 1 subunit delta.	T-complex protein 1, beta subunit, putative.	0.999
PMAA_013390	PMAA_096390	B6QVW3	B6QI47	T-complex protein 1 subunit delta.	T-complex protein 1, theta subunit, putative.	0.999
PMAA_023030	PMAA_013390	B6Q5F2	B6QVW3	T-complex protein 1 subunit gamma.	T-complex protein 1 subunit delta.	0.999
PMAA_023030	PMAA_026300	B6Q5F2	B6Q818	T-complex protein 1 subunit gamma.	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.	0.999
PMAA_023030	PMAA_032190	B6Q5F2	B6Q587	T-complex protein 1 subunit gamma.	T-complex protein 1, epsilon subunit, putative.	0.999
PMAA_023030	PMAA_035550	B6Q5F2	B6Q7M7	T-complex protein 1 subunit gamma.	Chaperonin, putative; Belongs to the GroES chaperonin family.	0.827
PMAA_023030	PMAA_042900	B6Q5F2	B6QR47	T-complex protein 1 subunit gamma.	Heat shock protein/chaperonin HSP78, putative; Belongs to the ClpA/ClpB family.	0.475
PMAA_023030	PMAA_045290	B6Q5F2	B6QQT5	T-complex protein 1 subunit gamma.	Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family.	0.403