137 items (Talaromyces marneffei) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PMAA_010700	Ribosomal small subunit assembly protein, putative. (326 aa)
	sts1	Tethering factor for nuclear proteasome sts1; Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity). (312 aa)
	PMAA_027130	ATP dependent RNA helicase (Dob1), putative. (1077 aa)
	PMAA_036840	Ulp1 protease family protein. (1029 aa)
	PMAA_027650	Ribosome biogenesis (Nop4), putative. (728 aa)
	PMAA_037690	RNA 3'-terminal phosphate cyclase, putative. (500 aa)
	PMAA_037920	rRNA biogenesis protein RRP5, putative. (1807 aa)
	PMAA_018290	DEAH-box RNA helicase (Dhr1), putative. (1203 aa)
	PMAA_018700	3' exoribonuclease family protein. (408 aa)
	PMAA_028310	U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family. (685 aa)
	PMAA_028830	Small nucleolar ribonucleoprotein complex subunit, putative. (625 aa)
	rps0	40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. (290 aa)
	PMAA_019760	Nucleolar protein nop5. (593 aa)
	PMAA_019890	Small nucleolar ribonucleoprotein complex subunit (SOF1), putative. (446 aa)
	PMAA_019950	ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family. (474 aa)
	PMAA_031010	RIO1 family protein kinase, putative. (423 aa)
	PMAA_021850	Exosome complex subunit Rrp46, putative. (249 aa)
	SPB1	AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (794 aa)
	PMAA_022180	Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (579 aa)
	PMAA_023640	ATP dependent RNA helicase (Dbp8), putative; Belongs to the DEAD box helicase family. (538 aa)
	PMAA_023770	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (201 aa)
	PMAA_024100	Uncharacterized protein. (542 aa)
	PMAA_033560	Cell morphogenesis protein Las1, putative. (439 aa)
	PMAA_033570	Uncharacterized protein. (330 aa)
	PMAA_033870	Exosome complex subunit Csl4, putative. (247 aa)
	PMAA_024690	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (162 aa)
	PMAA_024830	40S ribosomal protein S3, putative; Belongs to the universal ribosomal protein uS3 family. (266 aa)
	PMAA_034360	60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (184 aa)
	PMAA_025340	Ribosomal protein S23 (S12); Belongs to the universal ribosomal protein uS12 family. (145 aa)
	utp25	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2. (734 aa)
	ERB1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (768 aa)
	PMAA_035130	Ribosome biogenesis protein (Bms1), putative. (1184 aa)
	PMAA_025780	Exosome complex exonuclease Rrp6, putative. (795 aa)
	PMAA_016360	Ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family. (259 aa)
	TSR3	Ribosome biogenesis protein TSR3; Ribosome biogenesis protein required for processing 35S pre- rRNA at site D; Belongs to the TSR3 family. (391 aa)
	PMAA_026340	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family. (119 aa)
	PMAA_069050	Protein required for cell viability Rrp17, putative. (213 aa)
	PMAA_069720	60S ribosomal protein L18. (184 aa)
	PMAA_070680	U3 small nucleolar ribonucleoprotein subunit (Imp3), putative. (188 aa)
	PMAA_071170	Exosome complex endonuclease 2/ribosomal RNA processing protein, putative. (294 aa)
	PMAA_071570	Exonuclease, putative. (309 aa)
	PMAA_072170	rRNA processing protein (Ebp2), putative. (365 aa)
	PMAA_072340	Uncharacterized protein. (541 aa)
	PMAA_072370	Uncharacterized protein. (386 aa)
	PMAA_072730	HEAT repeat protein (DRIM), putative. (2622 aa)
	PMAA_063720	SSU processome component Utp10, putative. (1802 aa)
	PMAA_064100	Ribosomal protein S13p/S18e; Belongs to the universal ribosomal protein uS13 family. (155 aa)
	PMAA_073940	40S ribosomal protein S5, putative; Belongs to the universal ribosomal protein uS7 family. (213 aa)
	PMAA_074440	U3 small nucleolar RNA-associated protein Utp11, putative. (285 aa)
	PMAA_065700	Fibrillarin. (316 aa)
	PMAA_065840	40S ribosomal protein S22; Belongs to the universal ribosomal protein uS8 family. (130 aa)
	PMAA_066390	ATP dependent RNA helicase (Rok1), putative. (745 aa)
	PMAA_076140	3' exoribonuclease family protein (Rrp42), putative. (401 aa)
	PMAA_066660	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (98 aa)
	PMAA_067050	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (1042 aa)
	PMAA_067630	U3 small nucleolar ribonucleoprotein protein IMP4, putative. (319 aa)
	PMAA_087110	40S ribosomal protein S29, putative. (56 aa)
	PMAA_078260	40S ribosomal protein S10b. (161 aa)
	NOP7	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (675 aa)
	PMAA_081980	Small nucleolar ribonucleoprotein complex subunit (Pwp2), putative. (882 aa)
	PMAA_082340	Ulp1 protease family protein. (1082 aa)
	PMAA_083490	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family. (443 aa)
	PMAA_084220	3' exoribonuclease family protein. (333 aa)
	PMAA_084370	60S ribosomal protein L8, putative. (254 aa)
	PMAA_084500	Low-temperature viability protein ltv1. (489 aa)
	PMAA_084540	RIX1 domain-containing protein. (787 aa)
	rps1	40S ribosomal protein S1; Belongs to the eukaryotic ribosomal protein eS1 family. (256 aa)
	PMAA_092820	Small nucleolar ribonucleoprotein complex subunit, putative. (540 aa)
	PMAA_092830	Pre-rRNA processing protein Tsr1, putative. (809 aa)
	PMAA_093070	Uncharacterized protein. (217 aa)
	PMAA_093430	rRNA processing protein Ipi1, putative. (343 aa)
	PMAA_094000	Small nucleolar ribonucleoprotein complex subunit, putative. (631 aa)
	PMAA_094040	Small nucleolar ribonucleoprotein complex subunit, putative. (955 aa)
	YTM1	Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (485 aa)
	PMAA_094170	40S ribosomal protein S13; Belongs to the universal ribosomal protein uS13 family. (119 aa)
	PMAA_094760	Small nucleolar ribonucleoprotein complex subunit, putative. (968 aa)
	PMAA_096350	30S ribosomal subunit S4, putative. (439 aa)
	PMAA_054600	40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family. (200 aa)
	PMAA_054660	Small nucleolar ribonucleoprotein complex subunit Utp14, putatrive. (969 aa)
	PMAA_055530	40S ribosomal protein S19. (149 aa)
	PMAA_055690	Ribosomal protein L34 protein, putative. (120 aa)
	PMAA_057350	60S ribosomal protein L37a. (91 aa)
	PMAA_057510	Uncharacterized protein. (311 aa)
	PMAA_057590	40S ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family. (161 aa)
	PMAA_057870	40S ribosomal protein S8. (180 aa)
	PMAA_011490	60S ribosomal protein L28. (155 aa)
	PMAA_059220	Ribonuclease P complex subunit Pop2, putative. (301 aa)
	PMAA_059410	RNA-3'-phosphate cyclase family protein. (404 aa)
	PMAA_060080	40S ribosomal protein S15, putative; Belongs to the universal ribosomal protein uS19 family. (153 aa)
	PMAA_060200	rRNA maturation protein (Nop14), putative. (917 aa)
	PMAA_051000	Uncharacterized protein. (463 aa)
	PMAA_051800	Small nucleolar ribonucleoprotein complex subunit Dip2, putative. (957 aa)
	PMAA_052280	40S ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family. (151 aa)
	NAT10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1063 aa)
	PMAA_047240	Exosome complex endonuclease 1/ribosomal RNA processing protein, putative. (283 aa)
	PMAA_047530	40S ribosomal protein S17, putative. (139 aa)
	PMAA_047690	40S ribosomal protein Rps16, putative; Belongs to the universal ribosomal protein uS9 family. (143 aa)
	PMAA_047730	40S ribosomal protein S11; Belongs to the universal ribosomal protein uS11 family. (151 aa)
	PMAA_049520	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (401 aa)
	PMAA_044800	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (126 aa)
	PMAA_048600	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (349 aa)
	PMAA_040530	Small nucleolar ribonucleoprotein complex component (Utp5), putative. (851 aa)
	PMAA_040590	Uncharacterized protein. (264 aa)
	PMAA_040730	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (237 aa)
	PMAA_042170	Ribonuclease P protein subunit p40, putative. (372 aa)
	PMAA_045350	RNA processing protein Grc3, putative. (813 aa)
	PMAA_045010	Casein kinase I, putative; Belongs to the protein kinase superfamily. (402 aa)
	PMAA_045180	Exosome complex exonuclease Rrp40, putative. (279 aa)
	PMAA_042700	Ribosomal RNA processing protein, putative. (338 aa)
	PMAA_042920	Sas10/Utp3 family protein. (650 aa)
	PMAA_045820	rRNA processing protein Utp6, putative. (394 aa)
	PMAA_046010	Pre-rRNA processing nucleolar protein Sik1, putative. (507 aa)
	PMAA_046470	rRNA processing protein (Rrp20), putative. (257 aa)
	PMAA_046430	Methyltransferase, putative. (281 aa)
	PMAA_046730	Small nucleolar ribonucleoprotein complex subunit Utp15, putative. (540 aa)
	PMAA_043820	GTP binding protein, putative. (549 aa)
	PMAA_002720	40S ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. (191 aa)
	PMAA_002990	MYB DNA-binding domain protein. (690 aa)
	PMAA_003040	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (261 aa)
	PMAA_003430	Ribosomal assembly complex component Ipi3, putative. (563 aa)
	PMAA_004200	RNA processing protein Emg1, putative. (262 aa)
	PMAA_003310	40S ribosomal protein S27. (82 aa)
	PMAA_003750	Exosome-associated family protein. (288 aa)
	PMAA_004820	Exosome complex exonuclease Rrp4, putative. (380 aa)
	PMAA_004830	Ribosomal protein l7ae, putative. (127 aa)
	PMAA_005260	U3 small nucleolar RNA-associated protein 22. (1110 aa)
	PMAA_005490	DUF652 domain protein. (190 aa)
	PMAA_005510	SnoRNA binding protein, putative. (1022 aa)
	PMAA_005660	rRNA processing protein Bystin, putative. (507 aa)
	PMAA_008870	40S ribosomal protein S10a. (116 aa)
	PMAA_009210	Ribosome biogenesis protein Noc4, putative. (560 aa)
	PMAA_009840	Ribosomal protein S28e. (68 aa)
	PMAA_010200	U3 small nucleolar ribonucleoprotein protein Lcp5, putative. (398 aa)
	cnxG	Molybdopterin synthase sulfur carrier subunit; Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by UBA4. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin. (92 aa)
	PMAA_011130	WD repeat protein. (885 aa)
	rrp36	rRNA biogenesis protein rrp36; Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity). (357 aa)
	PMAA_010580	40S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family. (218 aa)

Your Current Organism:

Talaromyces marneffei

NCBI taxonomy Id: 441960
Other names: Penicillium marneffei ATCC 18224, T. marneffei ATCC 18224, Talaromyces marneffei ATCC 18224

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ERB1	NAT10	B6Q718	B6QNQ7	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	0.875
ERB1	NOP7	B6Q718	B6QEM7	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.999
ERB1	PMAA_003430	B6Q718	B6QSZ2	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosomal assembly complex component Ipi3, putative.	0.970
ERB1	PMAA_004200	B6Q718	B6QT36	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	RNA processing protein Emg1, putative.	0.449
ERB1	PMAA_004830	B6Q718	B6QTI2	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosomal protein l7ae, putative.	0.681
ERB1	PMAA_005260	B6Q718	B6QTJ8	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	U3 small nucleolar RNA-associated protein 22.	0.819
ERB1	PMAA_005510	B6Q718	B6QTN8	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	SnoRNA binding protein, putative.	0.863
ERB1	PMAA_005660	B6Q718	B6QTQ3	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	rRNA processing protein Bystin, putative.	0.867
ERB1	PMAA_009210	B6Q718	B6QUH8	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosome biogenesis protein Noc4, putative.	0.724
ERB1	PMAA_010200	B6Q718	B6QUS6	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	U3 small nucleolar ribonucleoprotein protein Lcp5, putative.	0.521
ERB1	PMAA_010700	B6Q718	B6QV12	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosomal small subunit assembly protein, putative.	0.458
ERB1	PMAA_011130	B6Q718	B6QUX1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD repeat protein.	0.819
ERB1	PMAA_018290	B6Q718	B6Q2G3	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	DEAH-box RNA helicase (Dhr1), putative.	0.534
ERB1	PMAA_019760	B6Q718	B6Q3H1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Nucleolar protein nop5.	0.962
ERB1	PMAA_019890	B6Q718	B6Q3I7	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Small nucleolar ribonucleoprotein complex subunit (SOF1), putative.	0.508
ERB1	PMAA_019950	B6Q718	B6Q3J3	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	ATP-dependent RNA helicase, putative; Belongs to the DEAD box helicase family.	0.898
ERB1	PMAA_023640	B6Q718	B6Q5S8	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	ATP dependent RNA helicase (Dbp8), putative; Belongs to the DEAD box helicase family.	0.757
ERB1	PMAA_024100	B6Q718	B6Q643	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.642
ERB1	PMAA_024690	B6Q718	B6Q6H2	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family.	0.642
ERB1	PMAA_027130	B6Q718	B6Q1K6	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	ATP dependent RNA helicase (Dob1), putative.	0.830