53 items (Talaromyces marneffei) - STRING interaction network

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

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	PMAA_017260	Phosphoglucomutase PgmA; Belongs to the phosphohexose mutase family. (555 aa)
	PMAA_036930	Adenosine kinase, putative. (349 aa)
	PMAA_027890	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (872 aa)
	PMAA_019200	Transthyretin domain protein. (173 aa)
	PMAA_019740	Ribose-phosphate pyrophosphokinase. (434 aa)
	PMAA_022720	Allantoicase Alc, putative. (379 aa)
	PMAA_071520	Inosine triphosphate pyrophosphatase, putative. (222 aa)
	PMAA_071870	Adenylate cyclase AcyA. (2152 aa)
	PMAA_063380	Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (470 aa)
	PMAA_073170	Ribonucleotide reductase small subunit RnrA, putative. (406 aa)
	PMAA_074670	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Belongs to the adenylosuccinate synthetase family. (422 aa)
	PMAA_067820	Adenosine deaminase, putative. (373 aa)
	PMAA_077600	Adenosine deaminase, putative. (376 aa)
	PMAA_077860	CECR1 family adenosine deaminase, putative. (571 aa)
	PMAA_087670	Phosphoglucomutase, putative. (609 aa)
	PMAA_080930	Phosphoribosylformylglycinamidine synthase. (1361 aa)
	PMAA_082140	Exopolyphosphatase, putative. (499 aa)
	PMAA_082210	Nucleoside diphosphate kinase. (153 aa)
	PMAA_083730	MutT/nudix family protein; Belongs to the Nudix hydrolase family. (215 aa)
	PMAA_083740	NUDIX family hydrolase, putative. (341 aa)
	PMAA_086270	Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (179 aa)
	PMAA_086280	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (187 aa)
	PMAA_094220	Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (594 aa)
	ADK1	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (272 aa)
	PMAA_098940	GMP synthase. (542 aa)
	PMAA_091590	Ribose phosphate diphosphokinase Prs1, putative. (477 aa)
	PMAA_092050	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (482 aa)
	PMAA_054270	Urease; In the C-terminal section; belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (836 aa)
	PMAA_057700	Pyruvate kinase; Belongs to the pyruvate kinase family. (525 aa)
	PMAA_059080	Ureidoglycolate hydrolase, putative. (368 aa)
	PMAA_059510	Bis(5'-nucleosyl)-tetraphosphatase, putative. (366 aa)
	PMAA_060590	AMP deaminase Amd1, putative. (1061 aa)
	PMAA_050780	Ribose-phosphate pyrophosphokinase 1, putative. (323 aa)
	ADK2	GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (250 aa)
	PMAA_053560	Phosphodiesterase. (919 aa)
	PMAA_047170	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (545 aa)
	PMAA_047880	Phosphoribosylglycinamide formyltransferase, putative. (224 aa)
	PMAA_047670	Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family. (302 aa)
	PMAA_049470	Bis(5'-adenosyl)-triphosphatase. (194 aa)
	PMAA_040230	Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (573 aa)
	PMAA_040720	Phosphoribosyl diphosphate synthase isoform 4. (320 aa)
	PMAA_040820	Xanthine dehydrogenase HxA, putative. (1359 aa)
	PMAA_042500	Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (212 aa)
	PMAA_045270	Allantoinase Dal1, putative. (531 aa)
	PMAA_046160	Guanylate kinase. (200 aa)
	MET3	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family. (573 aa)
	PMAA_004100	Phosphoribosyl-aminoimidazole-succinocarboxamide synthase. (302 aa)
	PMAA_005890	Chlorohydrolase family protein. (512 aa)
	PMAA_006560	IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation. (420 aa)
	PMAA_010820	Adenine phosphoribosyltransferase 1. (211 aa)
	PMAA_011320	Purine nucleoside phosphorylase I, inosine and guanosine-specific. (231 aa)
	PMAA_012300	Bifunctional purine biosynthetic protein Ade1, putative. (820 aa)
	PMAA_012960	Amidophosphoribosyltransferase. (544 aa)

Your Current Organism:

Talaromyces marneffei

NCBI taxonomy Id: 441960
Other names: Penicillium marneffei ATCC 18224, T. marneffei ATCC 18224, Talaromyces marneffei ATCC 18224

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADK1	ADK2	B6QI08	B6QNP3	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	0.909
ADK1	PMAA_010820	B6QI08	B6QV11	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Adenine phosphoribosyltransferase 1.	0.974
ADK1	PMAA_011320	B6QI08	B6QV80	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Purine nucleoside phosphorylase I, inosine and guanosine-specific.	0.473
ADK1	PMAA_027890	B6QI08	B6Q271	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.970
ADK1	PMAA_036930	B6QI08	B6Q1Q0	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Adenosine kinase, putative.	0.971
ADK1	PMAA_046160	B6QI08	B6QRF0	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Guanylate kinase.	0.696
ADK1	PMAA_053560	B6QI08	B6QNR4	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Phosphodiesterase.	0.930
ADK1	PMAA_057700	B6QI08	B6QLL0	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.918
ADK1	PMAA_060590	B6QI08	B6QMJ1	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	AMP deaminase Amd1, putative.	0.937
ADK1	PMAA_071870	B6QI08	B6Q9G2	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Adenylate cyclase AcyA.	0.463
ADK1	PMAA_073170	B6QI08	B6QAE5	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Ribonucleotide reductase small subunit RnrA, putative.	0.961
ADK1	PMAA_082210	B6QI08	B6QFI0	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Nucleoside diphosphate kinase.	0.969
ADK1	PMAA_086270	B6QI08	B6QGQ4	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation.	0.930
ADK1	PMAA_092050	B6QI08	B6QK48	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.964
ADK1	PMAA_094220	B6QI08	B6QHG8	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.	0.617
ADK2	ADK1	B6QNP3	B6QI08	GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.	0.909
ADK2	PMAA_010820	B6QNP3	B6QV11	GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	Adenine phosphoribosyltransferase 1.	0.970
ADK2	PMAA_011320	B6QNP3	B6QV80	GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	Purine nucleoside phosphorylase I, inosine and guanosine-specific.	0.497
ADK2	PMAA_027890	B6QNP3	B6Q271	GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.970
ADK2	PMAA_036930	B6QNP3	B6Q1Q0	GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	Adenosine kinase, putative.	0.954