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PMAA_017450 PMAA_017450 PMAA_017460 PMAA_017460 PMAA_017710 PMAA_017710 PMAA_017820 PMAA_017820 PMAA_018350 PMAA_018350 PMAA_018400 PMAA_018400 PMAA_018620 PMAA_018620 PMAA_028880 PMAA_028880 PMAA_019740 PMAA_019740 PMAA_021040 PMAA_021040 PMAA_021180 PMAA_021180 PMAA_030730 PMAA_030730 PMAA_022060 PMAA_022060 PMAA_032350 PMAA_032350 PMAA_023750 PMAA_023750 PMAA_033510 PMAA_033510 PMAA_024040 PMAA_024040 PMAA_033670 PMAA_033670 PMAA_033950 PMAA_033950 PMAA_025370 PMAA_025370 PMAA_016050 PMAA_016050 PMAA_035620 PMAA_035620 PMAA_026490 PMAA_026490 PMAA_068940 PMAA_068940 PMAA_070220 PMAA_070220 PMAA_070640 PMAA_070640 PMAA_062450 PMAA_062450 PMAA_072480 PMAA_072480 PMAA_064290 PMAA_064290 PMAA_064490 PMAA_064490 PMAA_065730 PMAA_065730 PMAA_066820 PMAA_066820 PMAA_066970 PMAA_066970 PMAA_067300 PMAA_067300 PMAA_068140 PMAA_068140 PMAA_087230 PMAA_087230 PMAA_087360 PMAA_087360 PMAA_087680 PMAA_087680 PMAA_079040 PMAA_079040 PMAA_088590 PMAA_088590 PMAA_088600 PMAA_088600 PMAA_079410 PMAA_079410 PMAA_089130 PMAA_089130 PMAA_089220 PMAA_089220 PMAA_089440 PMAA_089440 PMAA_080470 PMAA_080470 PMAA_081340 PMAA_081340 PMAA_082190 PMAA_082190 PMAA_083110 PMAA_083110 PMAA_083220 PMAA_083220 PMAA_084950 PMAA_084950 PMAA_085700 PMAA_085700 PMAA_085820 PMAA_085820 PMAA_086340 PMAA_086340 PMAA_093840 PMAA_093840 PMAA_094260 PMAA_094260 PMAA_094390 PMAA_094390 PMAA_094670 PMAA_094670 PMAA_095310 PMAA_095310 PMAA_095340 PMAA_095340 PMAA_096370 PMAA_096370 PMAA_097710 PMAA_097710 PMAA_097760 PMAA_097760 PMAA_100590 PMAA_100590 PMAA_091390 PMAA_091390 PMAA_091590 PMAA_091590 PMAA_091620 PMAA_091620 PMAA_091680 PMAA_091680 PMAA_101670 PMAA_101670 PMAA_057700 PMAA_057700 PMAA_058760 PMAA_058760 PMAA_060380 PMAA_060380 PMAA_050780 PMAA_050780 PMAA_051200 PMAA_051200 PMAA_051550 PMAA_051550 PMAA_051990 PMAA_051990 PMAA_052110 PMAA_052110 PMAA_052560 PMAA_052560 PMAA_047770 PMAA_047770 PMAA_047760 PMAA_047760 PMAA_049320 PMAA_049320 PMAA_049630 PMAA_049630 PMAA_048540 PMAA_048540 PMAA_040380 PMAA_040380 PMAA_039680 PMAA_039680 PMAA_039940 PMAA_039940 PMAA_040720 PMAA_040720 PMAA_041660 PMAA_041660 PMAA_041020 PMAA_041020 PMAA_041280 PMAA_041280 PMAA_042030 PMAA_042030 PMAA_042470 PMAA_042470 PMAA_042540 PMAA_042540 PMAA_045410 PMAA_045410 PMAA_045430 PMAA_045430 PMAA_046420 PMAA_046420 PMAA_048220 PMAA_048220 PMAA_048230 PMAA_048230 PMAA_044020 PMAA_044020 PMAA_001490 PMAA_001490 PMAA_002280 PMAA_002280 PMAA_002290 PMAA_002290 PMAA_003460 PMAA_003460 PMAA_005300 PMAA_005300 PMAA_005610 PMAA_005610 PMAA_005900 PMAA_005900 PMAA_006650 PMAA_006650 PMAA_009180 PMAA_009180 PMAA_011020 PMAA_011020 PMAA_011780 PMAA_011780 PMAA_011500 PMAA_011500 PMAA_012920 PMAA_012920 PMAA_013220 PMAA_013220 PMAA_014040 PMAA_014040 PMAA_014550 PMAA_014550 PMAA_013370 PMAA_013370 PMAA_014760 PMAA_014760
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PMAA_017450Isocitrate lyase. (594 aa)
PMAA_017460Citrate synthase; Belongs to the citrate synthase family. (467 aa)
PMAA_017710Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family. (745 aa)
PMAA_017820Phosphotransferase. (501 aa)
PMAA_018350Aspartate transaminase, putative. (431 aa)
PMAA_018400Fumarate hydratase, putative. (531 aa)
PMAA_018620Phosphotransferase. (495 aa)
PMAA_028880Phosphotransferase. (490 aa)
PMAA_019740Ribose-phosphate pyrophosphokinase. (434 aa)
PMAA_021040Malate synthase; Belongs to the malate synthase family. (539 aa)
PMAA_021180Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (360 aa)
PMAA_030730Alanine aminotransferase, putative. (534 aa)
PMAA_022060S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (380 aa)
PMAA_032350Phosphoenolpyruvate carboxykinase AcuF. (604 aa)
PMAA_023750Probable acetate kinase. (452 aa)
PMAA_033510Dihydroxyacetone kinase (DakA), putative. (588 aa)
PMAA_024040L-serine dehydratase, putative. (349 aa)
PMAA_0336703-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (489 aa)
PMAA_033950Triosephosphate isomerase. (249 aa)
PMAA_025370Aminotransferase, class V, putative. (386 aa)
PMAA_016050Acetyl-CoA-acetyltransferase, putative; Belongs to the thiolase-like superfamily. Thiolase family. (428 aa)
PMAA_035620Ribose 5-phosphate isomerase A. (323 aa)
PMAA_0264903-hydroxyisobutyrate dehydrogenase, putative. (318 aa)
PMAA_068940Phosphotransferase. (543 aa)
PMAA_070220Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (535 aa)
PMAA_070640Malic enzyme. (660 aa)
PMAA_0624502-hydroxyacid dehydrogenase, putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (344 aa)
PMAA_0724806-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (508 aa)
PMAA_064290Pyruvate dehydrogenase, putative. (406 aa)
PMAA_0644906-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (517 aa)
PMAA_065730Succinate dehydrogenase [ubiquinone] cytochrome b small subunit. (179 aa)
PMAA_066820Phosphotransferase. (553 aa)
PMAA_066970D-isomer specific 2-hydroxyacid dehydrogenase family protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (338 aa)
PMAA_067300Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (684 aa)
PMAA_068140Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (386 aa)
PMAA_087230Glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
PMAA_087360Aspartate aminotransferase. (466 aa)
PMAA_087680Dihydrolipoyl dehydrogenase. (510 aa)
PMAA_079040Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (785 aa)
PMAA_088590Peroxisomal multifunctional beta-oxidation protein (MFP), putative. (904 aa)
PMAA_088600Uncharacterized protein. (316 aa)
PMAA_079410Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (324 aa)
PMAA_089130Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (289 aa)
PMAA_089220Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (297 aa)
PMAA_089440Phosphoserine aminotransferase. (423 aa)
PMAA_080470Isocitrate lyase. (540 aa)
PMAA_081340Cysteine synthase (O-acetylserine (Thiol)-lyase) (Csase). (371 aa)
PMAA_082190Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (710 aa)
PMAA_083110Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (616 aa)
PMAA_083220Succinate dehydrogenase cytochrome b560 subunit. (186 aa)
PMAA_084950Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (330 aa)
PMAA_0857003-hydroxybutyryl-CoA dehydrogenase, putative. (320 aa)
PMAA_085820Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (444 aa)
PMAA_086340D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (479 aa)
PMAA_093840Enolase/allergen Asp F 22. (438 aa)
PMAA_094260Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1191 aa)
PMAA_094390L-serine dehydratase, putative. (452 aa)
PMAA_094670Threonine dehydratase. (562 aa)
PMAA_095310Citrate synthase; Belongs to the citrate synthase family. (472 aa)
PMAA_095340Homocysteine synthase CysD. (442 aa)
PMAA_096370Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (407 aa)
PMAA_097710Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (170 aa)
PMAA_0977603-hydroxyisobutyrate dehydrogenase, putative. (333 aa)
PMAA_100590Aspartate aminotransferase. (391 aa)
PMAA_091390Citrate synthase; Belongs to the citrate synthase family. (463 aa)
PMAA_091590Ribose phosphate diphosphokinase Prs1, putative. (477 aa)
PMAA_091620Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (472 aa)
PMAA_091680Malate dehydrogenase. (340 aa)
PMAA_101670Glucose-methanol-choline (Gmc) oxidoreductase, putative. (604 aa)
PMAA_057700Pyruvate kinase; Belongs to the pyruvate kinase family. (525 aa)
PMAA_058760Cysteine synthase, putative. (443 aa)
PMAA_060380Acetyl-CoA acetyltransferase, putative; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
PMAA_050780Ribose-phosphate pyrophosphokinase 1, putative. (323 aa)
PMAA_0512006-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (267 aa)
PMAA_051550FMN-dependent dehydrogenase family protein. (380 aa)
PMAA_051990Putative glutathione-dependent formaldehyde-activating enzyme; Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione; Belongs to the Gfa family. (187 aa)
PMAA_052110S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (288 aa)
PMAA_0525603-hydroxyisobutyrate dehydrogenase. (342 aa)
PMAA_047770Enoyl-CoA hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family. (295 aa)
PMAA_047760Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (500 aa)
PMAA_049320Succinate dehydrogenase, putative. (200 aa)
PMAA_049630O-acetylhomoserine (Thiol)-lyase, putative. (390 aa)
PMAA_048540Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (607 aa)
PMAA_040380Aspartate aminotransferase. (429 aa)
PMAA_039680Glyceraldehyde-3-phosphate dehydrogenase. (337 aa)
PMAA_039940Methylmalonate-semialdehyde dehydrogenase, putative. (591 aa)
PMAA_040720Phosphoribosyl diphosphate synthase isoform 4. (320 aa)
PMAA_041660Alpha-ketoglutarate dehydrogenase complex subunit Kgd1, putative. (1063 aa)
PMAA_041020Acetyl-coenzyme A synthetase. (668 aa)
PMAA_041280Fructose-1,6-bisphosphatase Fbp1, putative; Belongs to the FBPase class 1 family. (355 aa)
PMAA_042030Gluconokinase; Belongs to the gluconokinase GntK/GntV family. (239 aa)
PMAA_042470Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (485 aa)
PMAA_042540Succinyl-CoA synthetase subunit alpha, putative. (676 aa)
PMAA_045410Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (471 aa)
PMAA_045430Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent. (520 aa)
PMAA_046420Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (384 aa)
PMAA_048220Triosephosphate isomerase. (291 aa)
PMAA_048230Ribose-5-phosphate isomerase B, putative. (160 aa)
PMAA_044020Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (417 aa)
PMAA_001490Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (251 aa)
PMAA_002280Dihydroxyacetone kinase, putative. (457 aa)
PMAA_002290Dihydroxy-acetone synthase, putative. (722 aa)
PMAA_003460Phosphoserine phosphatase. (469 aa)
PMAA_005300Dihydrolipoamide succinyltransferase, putative. (476 aa)
PMAA_005610Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (376 aa)
PMAA_005900Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1073 aa)
PMAA_006650ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (804 aa)
PMAA_009180Formamidase FmdS. (415 aa)
PMAA_011020Malic enzyme. (577 aa)
PMAA_011780Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (406 aa)
PMAA_011500Malate dehydrogenase. (331 aa)
PMAA_012920Isocitrate dehydrogenase Idp1, putative. (820 aa)
PMAA_013220Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (510 aa)
PMAA_014040O-acetylhomoserine (Thiol)-lyase, putative. (442 aa)
PMAA_014550Pyridoxal-phosphate dependent enzyme, putative. (377 aa)
PMAA_013370Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (647 aa)
PMAA_014760Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family. (734 aa)
Your Current Organism:
Talaromyces marneffei
NCBI taxonomy Id: 441960
Other names: Penicillium marneffei ATCC 18224, T. marneffei ATCC 18224, Talaromyces marneffei ATCC 18224
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