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GM18_4386 GM18_4386 GM18_2460 GM18_2460 GM18_2458 GM18_2458 GM18_2457 GM18_2457 GM18_1974 GM18_1974 GM18_1962 GM18_1962 GM18_1865 GM18_1865 GM18_1864 GM18_1864 GM18_1863 GM18_1863 GM18_1856 GM18_1856 GM18_1852 GM18_1852 GM18_2758 GM18_2758 GM18_1850 GM18_1850 gcvH-2 gcvH-2 GM18_1231 GM18_1231 GM18_1054 GM18_1054 GM18_1030 GM18_1030 GM18_0920 GM18_0920 GM18_0490 GM18_0490 gcvPA gcvPA gcvH gcvH GM18_2756 GM18_2756 GM18_0460 GM18_0460 GM18_0201 GM18_0201 GM18_0154 GM18_0154 GM18_0153 GM18_0153 GM18_0152 GM18_0152 guaC guaC gpsA gpsA GM18_2793 GM18_2793 GM18_3110 GM18_3110 GM18_3190 GM18_3190 GM18_3456 GM18_3456 GM18_3547 GM18_3547 guaB guaB GM18_3646 GM18_3646 GM18_3647 GM18_3647 GM18_3695 GM18_3695 GM18_3792 GM18_3792 GM18_3918 GM18_3918 GM18_4126 GM18_4126 GM18_4384 GM18_4384 GM18_2725 GM18_2725
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GM18_4386PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: gem:GM21_4006 NADH dehydrogenase (ubiquinone) 24 kDa subunit. (168 aa)
GM18_2460KEGG: gme:Gmet_0332 respiratory nitrate reductase subunit gamma; TIGRFAM: respiratory nitrate reductase, gamma subunit; PFAM: Nitrate reductase gamma subunit. (221 aa)
GM18_2458KEGG: gme:Gmet_0330 respiratory nitrate reductase beta subunit; TIGRFAM: nitrate reductase, beta subunit. (484 aa)
GM18_2457TIGRFAM: nitrate reductase, alpha subunit; KEGG: gme:Gmet_0329 nitrate reductase subunit alpha; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1201 aa)
GM18_1974PFAM: catalytic domain-containing protein of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: gem:GM21_1974 branched-chain alpha-keto acid dehydrogenase subunit E2. (540 aa)
GM18_1962Formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; Contains selenocysteine; manually curated; KEGG: gem:GM21_1955 formate dehydrogenase, alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit. (1009 aa)
GM18_1865TIGRFAM: nitrogenase MoFe cofactor biosynthesis protein NifE; nitrogenase molybdenum-iron cofactor biosynthesis protein NifN; KEGG: gem:GM21_2142 bifunctional nitrogenase molybdenum-cofactor biosynthesis protein NifE/NifN; PFAM: oxidoreductase/nitrogenase component 1; Belongs to the NifD/NifK/NifE/NifN family. (918 aa)
GM18_1864Nitrogenase molybdenum-iron protein beta chain; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation; Belongs to the NifD/NifK/NifE/NifN family. (487 aa)
GM18_1863TIGRFAM: nitrogenase molybdenum-iron protein alpha chain; nitrogenase component I, alpha chain; KEGG: gem:GM21_2144 nitrogenase molybdenum-iron protein alpha chain; PFAM: oxidoreductase/nitrogenase component 1. (480 aa)
GM18_1856PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: pca:Pcar_1602 NADP-reducing hydrogenase chain A. (173 aa)
GM18_1852PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; nickel-dependent hydrogenase large subunit; KEGG: dma:DMR_02770 Ech hydrogenase subunit EchE; Belongs to the complex I 49 kDa subunit family. (358 aa)
GM18_2758Formate dehydrogenase, alpha subunit; KEGG: aar:Acear_2299 NAD-dependent formate dehydrogenase catalytic subunit; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; molybdopterin oxidoreductase Fe4S4 region. (926 aa)
GM18_1850PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: dma:DMR_02750 Ech hydrogenase subunit EchC. (164 aa)
gcvH-2Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa)
GM18_1231TIGRFAM: hydrogenase (NiFe) small subunit HydA; KEGG: gem:GM21_2914 hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit. (392 aa)
GM18_1054Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (745 aa)
GM18_1030SMART: PKD domain containing protein; KEGG: gsu:GSU3228 cytochrome c family protein. (992 aa)
GM18_0920KEGG: gem:GM21_3175 cytochrome c family protein. (266 aa)
GM18_0490PFAM: aminotransferase class V; KEGG: gbm:Gbem_0398 glycine dehydrogenase subunit 2. (479 aa)
gcvPAGlycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (445 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (123 aa)
GM18_2756PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: tai:Taci_0147 NADH dehydrogenase (ubiquinone) 24 kDa subunit. (180 aa)
GM18_0460TIGRFAM: hydrogenase (NiFe) small subunit HydA; KEGG: glo:Glov_2056 hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit. (379 aa)
GM18_0201SMART: HNH nuclease; KEGG: gbm:Gbem_0095 hypothetical protein. (616 aa)
GM18_0154PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: gbm:Gbem_0177 NADH dehydrogenase subunit E. (160 aa)
GM18_0153KEGG: gem:GM21_0158 NADH dehydrogenase (quinone); PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; Soluble ligand binding domain. (420 aa)
GM18_0152KEGG: gbm:Gbem_0175 NADH dehydrogenase subunit G; TIGRFAM: NADH-quinone oxidoreductase, chain G; PFAM: NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin. (644 aa)
guaCGuanosine monophosphate reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (347 aa)
gpsAPFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: gem:GM21_0007 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (335 aa)
GM18_2793PFAM: FAD linked oxidase domain protein; KEGG: gem:GM21_1319 FAD linked oxidase domain protein. (457 aa)
GM18_3110TIGRFAM: hydrogenase (NiFe) small subunit HydA; KEGG: gem:GM21_1123 hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit. (369 aa)
GM18_3190PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: gem:GM21_1073 NADH dehydrogenase (ubiquinone) 30 kDa subunit. (503 aa)
GM18_3456Glycerol-3-phosphate dehydrogenase; KEGG: gem:GM21_0871 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (537 aa)
GM18_3547Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (565 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (489 aa)
GM18_36462-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (431 aa)
GM18_3647SMART: Transketolase central region; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; KEGG: gbm:Gbem_0704 2-oxoglutarate dehydrogenase E1 component; PFAM: Transketolase central region; dehydrogenase E1 component. (897 aa)
GM18_3695PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; ferredoxin; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; molybdopterin oxidoreductase Fe4S4 region; KEGG: gbm:Gbem_0660 molybdopterin oxidoreductase. (822 aa)
GM18_3792PFAM: FAD linked oxidase domain protein; KEGG: gem:GM21_0577 FAD linked oxidase domain protein. (458 aa)
GM18_3918PFAM: catalytic domain-containing protein of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: gbm:Gbem_0461 branched-chain alpha-keto acid dehydrogenase subunit E2. (406 aa)
GM18_4126PFAM: iron permease FTR1; KEGG: rru:Rru_A2809 iron permease FTR1. (653 aa)
GM18_4384PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; ferredoxin; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; molybdopterin oxidoreductase Fe4S4 region; KEGG: gbm:Gbem_3920 molybdopterin oxidoreductase. (821 aa)
GM18_2725KEGG: gem:GM21_1350 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase; glutamate synthase alpha subunit domain protein; glutamine amidotransferase class-II. (1527 aa)
Your Current Organism:
Geobacter sp. M18
NCBI taxonomy Id: 443143
Other names: G. sp. M18
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