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GM18_0146 GM18_0146 GM18_4478 GM18_4478 nuoB nuoB nuoC-2 nuoC-2 nuoD nuoD GM18_4386 GM18_4386 GM18_4384 GM18_4384 GM18_4379 GM18_4379 GM18_4378 GM18_4378 GM18_4305 GM18_4305 GM18_4126 GM18_4126 GM18_4125 GM18_4125 GM18_4124 GM18_4124 GM18_3919 GM18_3919 GM18_3918 GM18_3918 GM18_3806 GM18_3806 GM18_3792 GM18_3792 GM18_3745 GM18_3745 GM18_3695 GM18_3695 GM18_3691 GM18_3691 GM18_3647 GM18_3647 GM18_3646 GM18_3646 guaB guaB GM18_3547 GM18_3547 GM18_3456 GM18_3456 GM18_3237 GM18_3237 GM18_3191 GM18_3191 GM18_3190 GM18_3190 GM18_3108 GM18_3108 GM18_2793 GM18_2793 GM18_2758 GM18_2758 GM18_2756 GM18_2756 GM18_2726 GM18_2726 GM18_2460 GM18_2460 GM18_2458 GM18_2458 GM18_2457 GM18_2457 GM18_2419 GM18_2419 GM18_2398 GM18_2398 GM18_2389 GM18_2389 GM18_2225 GM18_2225 GM18_1974 GM18_1974 GM18_1973 GM18_1973 GM18_1964 GM18_1964 GM18_1867 GM18_1867 GM18_1866 GM18_1866 GM18_1865 GM18_1865 GM18_1864 GM18_1864 GM18_1863 GM18_1863 GM18_1856 GM18_1856 GM18_1853 GM18_1853 GM18_1852 GM18_1852 GM18_1851 GM18_1851 GM18_1850 GM18_1850 GM18_1848 GM18_1848 pyrD pyrD GM18_1479 GM18_1479 gcvH-2 gcvH-2 GM18_1054 GM18_1054 GM18_1030 GM18_1030 GM18_0928 GM18_0928 GM18_0923 GM18_0923 GM18_0920 GM18_0920 GM18_0604 GM18_0604 GM18_0490 GM18_0490 gcvPA gcvPA gcvH gcvH GM18_0487 GM18_0487 GM18_0355 GM18_0355 GM18_0322 GM18_0322 GM18_0201 GM18_0201 nuoC nuoC GM18_0154 GM18_0154 GM18_0153 GM18_0153 GM18_0152 GM18_0152 GM18_0145 GM18_0145 guaC guaC GM18_0065 GM18_0065 GM18_0028 GM18_0028 gpsA gpsA
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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GM18_0146KEGG: gem:GM21_0151 proton-translocating NADH-quinone oxidoreductase, chain L; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein. (625 aa)
GM18_4478KEGG: gbm:Gbem_4023 hypothetical protein. (138 aa)
nuoBNADH-quinone oxidoreductase, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (170 aa)
nuoC-2NADH (or F420H2) dehydrogenase, subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family. (161 aa)
nuoDNADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family. (389 aa)
GM18_4386PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: gem:GM21_4006 NADH dehydrogenase (ubiquinone) 24 kDa subunit. (168 aa)
GM18_4384PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; ferredoxin; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; molybdopterin oxidoreductase Fe4S4 region; KEGG: gbm:Gbem_3920 molybdopterin oxidoreductase. (821 aa)
GM18_4379KEGG: gem:GM21_3999 proton-translocating NADH-quinone oxidoreductase, chain L; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein. (667 aa)
GM18_4378KEGG: gem:GM21_3998 proton-translocating NADH-quinone oxidoreductase, chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I). (545 aa)
GM18_4305KEGG: gbm:Gbem_3875 4Fe-4S ferredoxin iron-sulfur binding domain protein. (520 aa)
GM18_4126PFAM: iron permease FTR1; KEGG: rru:Rru_A2809 iron permease FTR1. (653 aa)
GM18_4125PFAM: Ferrous iron transport protein; KEGG: rru:Rru_A2808 hypothetical protein. (177 aa)
GM18_4124PFAM: Protein of unknown function DUF2318, membrane; YHS domain-containing protein; KEGG: rru:Rru_A2807 YHS. (489 aa)
GM18_3919KEGG: gem:GM21_0476 transketolase central region; PFAM: Transketolase central region; Transketolase domain-containing protein; SMART: Transketolase central region. (320 aa)
GM18_3918PFAM: catalytic domain-containing protein of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: gbm:Gbem_0461 branched-chain alpha-keto acid dehydrogenase subunit E2. (406 aa)
GM18_3806Hypothetical protein; Manually curated; KEGG: gem:GM21_0563 4Fe-4S ferredoxin iron-sulfur binding domain protein. (79 aa)
GM18_3792PFAM: FAD linked oxidase domain protein; KEGG: gem:GM21_0577 FAD linked oxidase domain protein. (458 aa)
GM18_3745TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; KEGG: gem:GM21_0622 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. (162 aa)
GM18_3695PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; ferredoxin; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; molybdopterin oxidoreductase Fe4S4 region; KEGG: gbm:Gbem_0660 molybdopterin oxidoreductase. (822 aa)
GM18_3691KEGG: gem:GM21_0677 polysulphide reductase-like protein. (451 aa)
GM18_3647SMART: Transketolase central region; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; KEGG: gbm:Gbem_0704 2-oxoglutarate dehydrogenase E1 component; PFAM: Transketolase central region; dehydrogenase E1 component. (897 aa)
GM18_36462-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (431 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (489 aa)
GM18_3547Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (565 aa)
GM18_3456Glycerol-3-phosphate dehydrogenase; KEGG: gem:GM21_0871 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (537 aa)
GM18_3237KEGG: gem:GM21_0031 heterodisulfide reductase subunit. (197 aa)
GM18_3191PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: gem:GM21_1072 NADH/ubiquinone/plastoquinone (complex I). (477 aa)
GM18_3190PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: gem:GM21_1073 NADH dehydrogenase (ubiquinone) 30 kDa subunit. (503 aa)
GM18_3108PFAM: Polysulphide reductase NrfD; KEGG: gbm:Gbem_3137 putative hydrogenase 2 b cytochrome subunit. (447 aa)
GM18_2793PFAM: FAD linked oxidase domain protein; KEGG: gem:GM21_1319 FAD linked oxidase domain protein. (457 aa)
GM18_2758Formate dehydrogenase, alpha subunit; KEGG: aar:Acear_2299 NAD-dependent formate dehydrogenase catalytic subunit; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; molybdopterin oxidoreductase Fe4S4 region. (926 aa)
GM18_2756PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: tai:Taci_0147 NADH dehydrogenase (ubiquinone) 24 kDa subunit. (180 aa)
GM18_2726KEGG: gem:GM21_1349 glutamate synthase, NADH/NADPH, small subunit; TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (493 aa)
GM18_2460KEGG: gme:Gmet_0332 respiratory nitrate reductase subunit gamma; TIGRFAM: respiratory nitrate reductase, gamma subunit; PFAM: Nitrate reductase gamma subunit. (221 aa)
GM18_2458KEGG: gme:Gmet_0330 respiratory nitrate reductase beta subunit; TIGRFAM: nitrate reductase, beta subunit. (484 aa)
GM18_2457TIGRFAM: nitrate reductase, alpha subunit; KEGG: gme:Gmet_0329 nitrate reductase subunit alpha; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1201 aa)
GM18_2419PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: glo:Glov_0215 NADH dehydrogenase (ubiquinone). (418 aa)
GM18_2398KEGG: glo:Glov_1160 MOSC domain containing protein. (127 aa)
GM18_2389PFAM: Cupin 2 conserved barrel domain protein; Carboxymuconolactone decarboxylase; KEGG: gur:Gura_4370 cupin 2 domain-containing protein. (367 aa)
GM18_2225PFAM: Polysulphide reductase NrfD; KEGG: gem:GM21_2236 putative hydrogenase 2 b cytochrome subunit. (417 aa)
GM18_1974PFAM: catalytic domain-containing protein of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: gem:GM21_1974 branched-chain alpha-keto acid dehydrogenase subunit E2. (540 aa)
GM18_1973Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (328 aa)
GM18_1964PFAM: Polysulphide reductase NrfD; KEGG: gbm:Gbem_2265 Polysulphide reductase NrfD. (403 aa)
GM18_1867TIGRFAM: ferredoxin III, nif-specific; KEGG: gem:GM21_2139 ferredoxin III, nif-specific. (87 aa)
GM18_1866KEGG: gem:GM21_2140 nitrogen fixation protein NifX; TIGRFAM: nitrogen fixation protein NifX; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein. (129 aa)
GM18_1865TIGRFAM: nitrogenase MoFe cofactor biosynthesis protein NifE; nitrogenase molybdenum-iron cofactor biosynthesis protein NifN; KEGG: gem:GM21_2142 bifunctional nitrogenase molybdenum-cofactor biosynthesis protein NifE/NifN; PFAM: oxidoreductase/nitrogenase component 1; Belongs to the NifD/NifK/NifE/NifN family. (918 aa)
GM18_1864Nitrogenase molybdenum-iron protein beta chain; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation; Belongs to the NifD/NifK/NifE/NifN family. (487 aa)
GM18_1863TIGRFAM: nitrogenase molybdenum-iron protein alpha chain; nitrogenase component I, alpha chain; KEGG: gem:GM21_2144 nitrogenase molybdenum-iron protein alpha chain; PFAM: oxidoreductase/nitrogenase component 1. (480 aa)
GM18_1856PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: pca:Pcar_1602 NADP-reducing hydrogenase chain A. (173 aa)
GM18_1853KEGG: dvm:DvMF_1523 4Fe-4S ferredoxin iron-sulfur binding domain protein. (125 aa)
GM18_1852PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; nickel-dependent hydrogenase large subunit; KEGG: dma:DMR_02770 Ech hydrogenase subunit EchE; Belongs to the complex I 49 kDa subunit family. (358 aa)
GM18_1851PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: dvl:Dvul_2504 ech hydrogenase, subunit EchD, putative. (134 aa)
GM18_1850PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: dma:DMR_02750 Ech hydrogenase subunit EchC. (164 aa)
GM18_1848PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; KEGG: dvm:DvMF_1518 NADH dehydrogenase (quinone). (667 aa)
pyrDDihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. (305 aa)
GM18_1479PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: gbm:Gbem_1648 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding. (325 aa)
gcvH-2Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa)
GM18_1054Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (745 aa)
GM18_1030SMART: PKD domain containing protein; KEGG: gsu:GSU3228 cytochrome c family protein. (992 aa)
GM18_0928PFAM: Protein of unknown function DUF2318, membrane; KEGG: gem:GM21_3166 hypothetical protein. (156 aa)
GM18_0923Alkylhydroperoxidase like protein, AhpD family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (110 aa)
GM18_0920KEGG: gem:GM21_3175 cytochrome c family protein. (266 aa)
GM18_0604PFAM: Protein of unknown function DUF2318, membrane; KEGG: gem:GM21_3547 membrane protein-like protein. (444 aa)
GM18_0490PFAM: aminotransferase class V; KEGG: gbm:Gbem_0398 glycine dehydrogenase subunit 2. (479 aa)
gcvPAGlycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (445 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (123 aa)
GM18_0487KEGG: gbm:Gbem_0395 glycine cleavage system T protein; TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel. (363 aa)
GM18_0355KEGG: nmu:Nmul_A1848 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; manually curated; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region. (315 aa)
GM18_0322KEGG: gem:GM21_0270 4Fe-4S ferredoxin iron-sulfur binding domain protein. (368 aa)
GM18_0201SMART: HNH nuclease; KEGG: gbm:Gbem_0095 hypothetical protein. (616 aa)
nuoCNADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family. In the C-terminal section; belongs to the complex I 49 kDa subunit family. (794 aa)
GM18_0154PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: gbm:Gbem_0177 NADH dehydrogenase subunit E. (160 aa)
GM18_0153KEGG: gem:GM21_0158 NADH dehydrogenase (quinone); PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; Soluble ligand binding domain. (420 aa)
GM18_0152KEGG: gbm:Gbem_0175 NADH dehydrogenase subunit G; TIGRFAM: NADH-quinone oxidoreductase, chain G; PFAM: NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin. (644 aa)
GM18_0145KEGG: gem:GM21_0150 proton-translocating NADH-quinone oxidoreductase, chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I). (496 aa)
guaCGuanosine monophosphate reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (347 aa)
GM18_0065KEGG: glo:Glov_1057 MauM/NapG family ferredoxin-type protein; TIGRFAM: MauM/NapG family ferredoxin-type protein; PFAM: Twin-arginine translocation pathway, signal sequence, subgroup. (220 aa)
GM18_0028KEGG: gem:GM21_0031 heterodisulfide reductase subunit. (194 aa)
gpsAPFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: gem:GM21_0007 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (335 aa)
Your Current Organism:
Geobacter sp. M18
NCBI taxonomy Id: 443143
Other names: G. sp. M18
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