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GM21_0622 GM21_0622 GM21_0839 GM21_0839 GM21_0897 GM21_0897 nrdR nrdR GM21_1226 GM21_1226 GM21_1227 GM21_1227 ribBA ribBA ribH ribH panB panB panC panC panD panD GM21_1411 GM21_1411 GM21_1596 GM21_1596 GM21_1627 GM21_1627 coaX coaX GM21_2184 GM21_2184 GM21_2317 GM21_2317 coaD coaD GM21_2404 GM21_2404 GM21_2546 GM21_2546 ribBA-2 ribBA-2 GM21_2858 GM21_2858 acpS acpS
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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GM21_0622KEGG: gbm:Gbem_0608 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. (162 aa)
GM21_08392-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (307 aa)
GM21_0897TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: gbm:Gbem_3348 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. (424 aa)
nrdRATP-cone domain protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (150 aa)
GM21_1226Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (369 aa)
GM21_1227KEGG: gbm:Gbem_3023 riboflavin synthase, alpha subunit; TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein. (214 aa)
ribBAGTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (400 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (155 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (289 aa)
panCPantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (279 aa)
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (134 aa)
GM21_1411PFAM: dihydrofolate reductase region; KEGG: gbm:Gbem_2799 dihydrofolate reductase region. (306 aa)
GM21_1596Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (278 aa)
GM21_1627TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; KEGG: gbm:Gbem_2599 riboflavin biosynthesis protein RibF; Belongs to the ribF family. (323 aa)
coaXPutative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (254 aa)
GM21_2184PFAM: protein of unknown function DUF479; KEGG: gbm:Gbem_2033 protein of unknown function DUF479. (196 aa)
GM21_2317TIGRFAM: methyltransferase; PFAM: Protein of unknown function methylase putative; putative RNA methylase; KEGG: gbm:Gbem_1892 methyltransferase. (193 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (161 aa)
GM21_2404KEGG: ppd:Ppro_0225 hypothetical protein. (151 aa)
GM21_2546Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (411 aa)
ribBA-2GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (400 aa)
GM21_28582-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (322 aa)
acpSHolo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (125 aa)
Your Current Organism:
Geobacter sp. M21
NCBI taxonomy Id: 443144
Other names: G. sp. M21
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