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| | GM21_0020 | TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: gbm:Gbem_0021 glutamate synthase (NADPH), homotetrameric. (469 aa) |
| | GM21_0021 | PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: gbm:Gbem_0022 oxidoreductase FAD/NAD(P)-binding domain protein. (282 aa) |
| | GM21_0175 | Glutamate dehydrogenase (NADP(+)); PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: gbm:Gbem_0193 Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (449 aa) |
| | GM21_0192 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_0209 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (1183 aa) |
| | GM21_0209 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (912 aa) |
| | sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (298 aa) |
| | sucC | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa) |
| | GM21_0258 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1148 aa) |
| | GM21_0264 | PFAM: Transketolase domain protein; KEGG: gbm:Gbem_0279 transketolase domain protein. (274 aa) |
| | GM21_0265 | PFAM: Transketolase central region; Transketolase domain protein; KEGG: gbm:Gbem_0280 transketolase central region. (310 aa) |
| | GM21_0316 | Methylmalonyl-CoA carboxytransferase; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; KEGG: gbm:Gbem_0334 conserved carboxylase domain protein. (501 aa) |
| | GM21_0317 | PFAM: carboxyl transferase; KEGG: gbm:Gbem_0335 carboxyl transferase. (514 aa) |
| | GM21_0318 | KEGG: gbm:Gbem_0336 hypothetical protein. (61 aa) |
| | GM21_0319 | PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: gbm:Gbem_0337 biotin/lipoyl attachment domain-containing protein. (131 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (409 aa) |
| | GM21_0351 | PFAM: ROK family protein; KEGG: gme:Gmet_2805 N-acetylglucosamine kinase. (304 aa) |
| | GM21_0389 | TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: gbm:Gbem_0395 glycine cleavage system T protein. (363 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (123 aa) |
| | gcvPA | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (445 aa) |
| | GM21_0392 | Glycine dehydrogenase (decarboxylating); PFAM: glycine cleavage system P-protein; KEGG: gbm:Gbem_0398 glycine dehydrogenase (decarboxylating). (479 aa) |
| | GM21_0393 | PFAM: biotin/lipoate A/B protein ligase; KEGG: gbm:Gbem_0399 biotin/lipoate A/B protein ligase. (267 aa) |
| | lipA | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (291 aa) |
| | pdhA | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (351 aa) |
| | GM21_0476 | PFAM: Transketolase central region; Transketolase domain protein; KEGG: gbm:Gbem_0460 transketolase central region. (320 aa) |
| | GM21_0477 | PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: gbm:Gbem_0461 catalytic domain of components of various dehydrogenase complexes. (405 aa) |
| | GM21_0478 | Glutamate dehydrogenase (NAD(P)(+)); PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: gur:Gura_2895 Glu/Leu/Phe/Val dehydrogenase, C terminal; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (363 aa) |
| | GM21_0485 | PFAM: acetyl-CoA hydrolase/transferase; KEGG: gbm:Gbem_0468 acetyl-CoA hydrolase/transferase. (531 aa) |
| | GM21_0585 | KEGG: gbm:Gbem_0572 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV. (356 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (214 aa) |
| | GM21_0641 | PFAM: aminotransferase class I and II; KEGG: gbm:Gbem_0627 aminotransferase class I and II. (434 aa) |
| | GM21_0654 | TIGRFAM: mercuric reductase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: gbm:Gbem_0640 mercuric reductase. (468 aa) |
| | GM21_0657 | KEGG: gbm:Gbem_0644 pyruvate, phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; Belongs to the PEP-utilizing enzyme family. (914 aa) |
| | GM21_0716 | KEGG: gbm:Gbem_0704 2-oxoglutarate dehydrogenase, E1 subunit; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component. (896 aa) |
| | GM21_0717 | 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (419 aa) |
| | GM21_0718 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: gme:Gmet_2764 dihydrolipoamide dehydrogenase. (470 aa) |
| | lipB | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (204 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (529 aa) |
| | pckG | Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (647 aa) |
| | GM21_0842 | PFAM: acetyl-CoA hydrolase/transferase; KEGG: gbm:Gbem_0795 acetyl-CoA hydrolase/transferase. (549 aa) |
| | GM21_0862 | PFAM: acylphosphatase; KEGG: gbm:Gbem_3384 acylphosphatase. (93 aa) |
| | GM21_0912 | TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; KEGG: gbm:Gbem_3334 succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family. (221 aa) |
| | GM21_0913 | KEGG: gbm:Gbem_3333 succinate dehydrogenase or fumarate reductase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein. (637 aa) |
| | GM21_0914 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_3332 4Fe-4S ferredoxin iron-sulfur binding domain protein. (246 aa) |
| | GM21_1031 | KEGG: gbm:Gbem_3234 1-phosphofructokinase; TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; Belongs to the carbohydrate kinase PfkB family. (311 aa) |
| | sucC-2 | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa) |
| | sucD-2 | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa) |
| | GM21_1159 | KEGG: gbm:Gbem_3103 sugar-phosphate isomerase, RpiB/LacA/LacB family; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase. (151 aa) |
| | GM21_1174 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_3087 4Fe-4S ferredoxin iron-sulfur binding domain protein. (67 aa) |
| | GM21_1175 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: gbm:Gbem_3086 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (356 aa) |
| | GM21_1176 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: gbm:Gbem_3085 thiamine pyrophosphate protein domain protein TPP-binding. (246 aa) |
| | GM21_1177 | TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: gbm:Gbem_3084 pyruvate/ketoisovalerate oxidoreductase, gamma subunit. (183 aa) |
| | GM21_1182 | PFAM: glutamine synthetase catalytic region; KEGG: gbm:Gbem_3079 glutamine synthetase catalytic region. (695 aa) |
| | GM21_1184 | TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: gbm:Gbem_3077 glutamine synthetase, type I. (470 aa) |
| | pfkA | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (361 aa) |
| | GM21_1324 | KEGG: gbm:Gbem_2901 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent monomeric type; Belongs to the monomeric-type IDH family. (743 aa) |
| | mdh | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (317 aa) |
| | GM21_1326 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_2899 4Fe-4S ferredoxin iron-sulfur binding domain protein. (64 aa) |
| | GM21_1327 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: gbm:Gbem_2898 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (377 aa) |
| | GM21_1328 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: gbm:Gbem_2897 thiamine pyrophosphate protein domain protein TPP-binding. (270 aa) |
| | GM21_1329 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: gbm:Gbem_2896 pyruvate ferredoxin/flavodoxin oxidoreductase. (182 aa) |
| | GM21_1349 | TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: gbm:Gbem_2867 glutamate synthase, NADH/NADPH, small subunit. (493 aa) |
| | GM21_1350 | PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: gbm:Gbem_2866 ferredoxin-dependent glutamate synthase. (1527 aa) |
| | GM21_1392 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (390 aa) |
| | GM21_1415 | PFAM: fumarate lyase; KEGG: gbm:Gbem_2795 fumarate lyase. (466 aa) |
| | GM21_1444 | PFAM: Glu/Leu/Phe/Val dehydrogenase; KEGG: gbm:Gbem_2777 Glu/Leu/Phe/Val dehydrogenase. (986 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (316 aa) |
| | GM21_1483 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (490 aa) |
| | ilvD | KEGG: gbm:Gbem_2747 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (553 aa) |
| | GM21_1495 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; KEGG: gbm:Gbem_2746 acetolactate synthase, large subunit, biosynthetic type. (566 aa) |
| | GM21_1496 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: gbm:Gbem_2745 acetolactate synthase, small subunit. (163 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (515 aa) |
| | leuC | Homoaconitate hydratase family protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (427 aa) |
| | GM21_1505 | PFAM: aconitate hydratase domain protein; KEGG: gbm:Gbem_2736 aconitate hydratase domain protein; Belongs to the LeuD family. (175 aa) |
| | pfkA-2 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa) |
| | GM21_1806 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1004 aa) |
| | fbp | Fructose-bisphosphatase; PFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: gbm:Gbem_2410 inositol phosphatase/fructose-16-bisphosphatase. (326 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa) |
| | pgk | PFAM: phosphoglycerate kinase; KEGG: gbm:Gbem_2337 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (399 aa) |
| | GM21_1884 | KEGG: gbm:Gbem_2336 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (331 aa) |
| | ackA-2 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (421 aa) |
| | GM21_1947 | KEGG: gbm:Gbem_2276 phosphate acetyltransferase; TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase. (333 aa) |
| | GM21_1966 | TIGRFAM: aconitate hydratase; PFAM: aconitate hydratase domain protein; KEGG: gbm:Gbem_2258 aconitate hydratase. (648 aa) |
| | pdhA-2 | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (325 aa) |
| | GM21_1973 | Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (328 aa) |
| | GM21_1974 | PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: gbm:Gbem_2250 catalytic domain of components of various dehydrogenase complexes. (486 aa) |
| | GM21_2050 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (934 aa) |
| | GM21_2146 | TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: gbm:Gbem_2073 homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (382 aa) |
| | glk | Glucokinase; KEGG: gbm:Gbem_2002 glucokinase; TIGRFAM: glucokinase; PFAM: Glucokinase; ROK family protein; Belongs to the bacterial glucokinase family. (327 aa) |
| | GM21_2256 | TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein; KEGG: gbm:Gbem_1961 D-3-phosphoglycerate dehydrogenase. (532 aa) |
| | GM21_2321 | PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase; KEGG: gbm:Gbem_1888 malic protein. (749 aa) |
| | GM21_2331 | KEGG: gbm:Gbem_1879 putative homoserine kinase; TIGRFAM: proposed homoserine kinase; phosphonopyruvate decarboxylase-related protein; PFAM: metalloenzyme domain protein. (399 aa) |
| | GM21_2515 | PFAM: Aldehyde Dehydrogenase; KEGG: gbm:Gbem_1707 aldehyde dehydrogenase. (539 aa) |
| | GM21_2561 | PFAM: Citrate synthase; KEGG: gbm:Gbem_1652 citrate synthase; Belongs to the citrate synthase family. (441 aa) |
| | gcvH-2 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa) |
| | sucD-3 | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (308 aa) |
| | sucC-3 | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (392 aa) |
| | GM21_2798 | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic protein NAD-binding; malic protein domain protein; KEGG: gbm:Gbem_1455 malic protein. (780 aa) |
| | GM21_2799 | TIGRFAM: oxaloacetate decarboxylase alpha subunit; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein; KEGG: gbm:Gbem_1454 oxaloacetate decarboxylase alpha subunit. (690 aa) |
| | GM21_2853 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: gme:Gmet_2118 FAD dependent oxidoreductase. (614 aa) |
| | GM21_2866 | PFAM: CoA-binding domain protein; KEGG: gbm:Gbem_1414 CoA-binding domain protein. (697 aa) |
| | tal-2 | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (374 aa) |
| | GM21_2903 | TIGRFAM: transketolase; PFAM: Transketolase central region; Transketolase domain protein; KEGG: gbm:Gbem_1379 transketolase; Belongs to the transketolase family. (711 aa) |
| | GM21_2957 | PFAM: ROK family protein; KEGG: gbm:Gbem_1326 ROK family protein. (306 aa) |
| | GM21_2959 | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase; PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase; KEGG: gbm:Gbem_1324 malic protein. (749 aa) |
| | GM21_2989 | TIGRFAM: aconitate hydratase 2; PFAM: Aconitase B, N-terminal; aconitate hydratase domain protein; KEGG: gbm:Gbem_1294 aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. (839 aa) |
| | GM21_2991 | KEGG: gbm:Gbem_1292 succinic semialdehyde dehydrogenase; TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family. (485 aa) |
| | GM21_3018 | KEGG: gbm:Gbem_1265 2-isopropylmalate synthase/homocitrate synthase family protein; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: LeuA allosteric (dimerisation) domain; pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (528 aa) |
| | GM21_3093 | KEGG: gbm:Gbem_1182 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. (481 aa) |
| | GM21_3253 | PFAM: ketose-bisphosphate aldolase class-II; KEGG: gbm:Gbem_1007 fructose/tagatose bisphosphate aldolase-like protein. (427 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa) |
| | GM21_3278 | KEGG: gbm:Gbem_0982 BioD-like protein N-terminal domain of phosphotransacetylase-like protein. (364 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (362 aa) |
| | GM21_3371 | Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (541 aa) |
| | GM21_3397 | PFAM: Transketolase central region; Transketolase domain protein; KEGG: bbt:BBta_5637 transketolase subunit B. (298 aa) |
| | GM21_3398 | PFAM: Transketolase domain protein; KEGG: bbt:BBta_5636 transketolase subunit A. (263 aa) |
| | pgi | PFAM: phosphoglucose isomerase (PGI); KEGG: gbm:Gbem_3417 phosphoglucose isomerase (PGI); Belongs to the GPI family. (530 aa) |
| | GM21_3566 | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: gme:Gmet_1896 dihydrolipoamide dehydrogenase. (452 aa) |
| | gpmA | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (234 aa) |
| | GM21_3593 | KEGG: gbm:Gbem_3527 ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (221 aa) |
| | GM21_3621 | PFAM: cyclase family protein; KEGG: gbm:Gbem_3555 cyclase family protein. (226 aa) |
| | GM21_3624 | PFAM: NUDIX hydrolase; KEGG: gbm:Gbem_3558 NUDIX hydrolase. (173 aa) |
| | GM21_3873 | KEGG: gbm:Gbem_3789 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (480 aa) |
| | GM21_3971 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_3883 4Fe-4S ferredoxin iron-sulfur binding domain protein. (84 aa) |
| | GM21_3982 | PFAM: acetyl-CoA hydrolase/transferase; KEGG: gbm:Gbem_3897 acetyl-CoA hydrolase/transferase. (520 aa) |
| | GM21_3990 | PFAM: Citrate synthase; KEGG: gbm:Gbem_3905 citrate synthase; Belongs to the citrate synthase family. (454 aa) |
| | GM21_4125 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_4034 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (1238 aa) |
| | GM21_4127 | KEGG: gbm:Gbem_4036 flavocytochrome c; TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; HI0933 family protein; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (598 aa) |
