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glmS glmS glmU glmU GM21_0358 GM21_0358 GM21_0359 GM21_0359 GM21_1028 GM21_1028 GM21_1029 GM21_1029 dacA dacA GM21_1598 GM21_1598 glmM glmM pdxJ pdxJ GM21_1703 GM21_1703 GM21_2649 GM21_2649 dacA-2 dacA-2 GM21_3384 GM21_3384 GM21_3385 GM21_3385 GM21_3386 GM21_3386 GM21_3387 GM21_3387 hprK hprK hpf hpf GM21_4050 GM21_4050
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
glmSGlucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (609 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (458 aa)
GM21_0358PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: gur:Gura_3514 pyridoxamine 5'-phosphate oxidase-related, FMN-binding. (134 aa)
GM21_0359Transcriptional regulator, MarR family; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: geo:Geob_1285 transcriptional regulator, MarR family. (141 aa)
GM21_1028PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: gbm:Gbem_3237 pyridoxamine 5'-phosphate oxidase-related FMN-binding. (144 aa)
GM21_1029Hypothetical protein. (242 aa)
dacAProtein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (252 aa)
GM21_1598PFAM: YbbR family protein; KEGG: gbm:Gbem_2636 hypothetical protein. (127 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (454 aa)
pdxJPyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (239 aa)
GM21_1703KEGG: gbm:Gbem_2516 PTSINtr with GAF domain, PtsP; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; PEP-utilising protein domain protein; PEP-utilising protein mobile region; GAF domain protein; SMART: GAF domain protein; Belongs to the PEP-utilizing enzyme family. (780 aa)
GM21_2649PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: gbm:Gbem_1567 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I. (474 aa)
dacA-2Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (388 aa)
GM21_3384Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (586 aa)
GM21_3385Phosphotransferase system, phosphocarrier protein HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr; KEGG: gbm:Gbem_0874 phosphotransferase system, phosphocarrier protein HPr. (88 aa)
GM21_3386PFAM: PTS system fructose subfamily IIA component; KEGG: gbm:Gbem_0873 PTS system fructose subfamily IIA component. (131 aa)
GM21_3387Conserved hypothetical protein; Displays ATPase and GTPase activities. (287 aa)
hprKHPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). (316 aa)
hpfSigma 54 modulation protein/ribosomal protein S30EA; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. (182 aa)
GM21_4050PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: gbm:Gbem_3964 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I. (469 aa)
Your Current Organism:
Geobacter sp. M21
NCBI taxonomy Id: 443144
Other names: G. sp. M21
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