STRINGSTRING
GM21_2815 GM21_2815 fdhD-2 fdhD-2 GM21_2824 GM21_2824 GM21_2862 GM21_2862 GM21_2906 GM21_2906 fdhD-3 fdhD-3 GM21_3943 GM21_3943 GM21_4123 GM21_4123 GM21_3982 GM21_3982 GM21_0072 GM21_0072 GM21_0342 GM21_0342 lipA lipA GM21_0485 GM21_0485 ttcA ttcA rimO rimO GM21_0643 GM21_0643 thiG thiG GM21_0667 GM21_0667 miaB miaB GM21_0842 GM21_0842 mnmA mnmA GM21_1265 GM21_1265 GM21_1370 GM21_1370 GM21_1387 GM21_1387 GM21_1388 GM21_1388 GM21_1436 GM21_1436 fdhD fdhD bioB bioB mnmA-2 mnmA-2 GM21_2570 GM21_2570 mobA-2 mobA-2 GM21_2647 GM21_2647
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GM21_2815PFAM: acetyl-CoA hydrolase/transferase; KEGG: gbm:Gbem_1439 acetyl-CoA hydrolase/transferase. (437 aa)
fdhD-2Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (255 aa)
GM21_2824PFAM: acetyl-CoA hydrolase/transferase; GCN5-related N-acetyltransferase; KEGG: gbm:Gbem_1430 acetyl-CoA hydrolase/transferase. (616 aa)
GM21_2862PFAM: acetyl-CoA hydrolase/transferase; KEGG: gbm:Gbem_1418 acetyl-CoA hydrolase/transferase. (445 aa)
GM21_2906SMART: Rhodanese domain protein; KEGG: gbm:Gbem_1375 rhodanese domain protein. (122 aa)
fdhD-3Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (255 aa)
GM21_3943KEGG: gbm:Gbem_3858 citrate lyase, alpha subunit; TIGRFAM: citrate lyase, alpha subunit; PFAM: Citrate lyase alpha subunit. (512 aa)
GM21_4123SMART: Rhodanese domain protein; KEGG: gur:Gura_0450 rhodanese domain-containing protein. (422 aa)
GM21_3982PFAM: acetyl-CoA hydrolase/transferase; KEGG: gbm:Gbem_3897 acetyl-CoA hydrolase/transferase. (520 aa)
GM21_0072PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; KEGG: gbm:Gbem_0089 rhodanese domain protein. (324 aa)
GM21_0342KEGG: gbm:Gbem_0361 PP-loop domain protein. (268 aa)
lipALipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (291 aa)
GM21_0485PFAM: acetyl-CoA hydrolase/transferase; KEGG: gbm:Gbem_0468 acetyl-CoA hydrolase/transferase. (531 aa)
ttcAPP-loop domain protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (255 aa)
rimOMiaB-like tRNA modifying enzyme YliG; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (448 aa)
GM21_0643PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: gbm:Gbem_0629 glyoxalase/bleomycin resistance protein/dioxygenase. (117 aa)
thiGThiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (260 aa)
GM21_0667TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: gbm:Gbem_0654 thiamine biosynthesis protein ThiS. (75 aa)
miaBtRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (441 aa)
GM21_0842PFAM: acetyl-CoA hydrolase/transferase; KEGG: gbm:Gbem_0795 acetyl-CoA hydrolase/transferase. (549 aa)
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (355 aa)
GM21_1265PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: gbm:Gbem_2960 glyoxalase/bleomycin resistance protein/dioxygenase. (157 aa)
GM21_1370PFAM: acetyl-CoA hydrolase/transferase; KEGG: gbm:Gbem_2843 acetyl-CoA hydrolase/transferase. (519 aa)
GM21_1387PFAM: coenzyme A transferase; KEGG: gbm:Gbem_2825 coenzyme A transferase. (320 aa)
GM21_1388PFAM: coenzyme A transferase; KEGG: gbm:Gbem_2824 coenzyme A transferase. (274 aa)
GM21_1436PFAM: Arylsulfotransferase; KEGG: geo:Geob_2732 arylsulfotransferase. (625 aa)
fdhDFormate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the MobA family. (468 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (328 aa)
mnmA-2tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (359 aa)
GM21_2570KEGG: gbm:Gbem_1643 MiaB-like tRNA modifying enzyme; TIGRFAM: MiaB-like tRNA modifying enzyme; RNA modification enzyme, MiaB family; PFAM: Protein of unknown function UPF0004; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (429 aa)
mobA-2Formate dehydrogenase family accessory protein FdhD; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (235 aa)
GM21_2647Cysteine desulfurase NifS; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. (389 aa)
Your Current Organism:
Geobacter sp. M21
NCBI taxonomy Id: 443144
Other names: G. sp. M21
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.