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nuoN-2 nuoN-2 GM21_0159 GM21_0159 GM21_0673 GM21_0673 GM21_0690 GM21_0690 GM21_0867 GM21_0867 GM21_1065 GM21_1065 GM21_1069 GM21_1069 GM21_1070 GM21_1070 GM21_1071 GM21_1071 GM21_1072 GM21_1072 GM21_1126 GM21_1126 nuoK1 nuoK1 GM21_4115 GM21_4115 GM21_4114 GM21_4114 GM21_4006 GM21_4006 GM21_4004 GM21_4004 nuoK2 nuoK2 GM21_0151 GM21_0151 GM21_0150 GM21_0150 nuoN nuoN GM21_0077 GM21_0077 GM21_0043 GM21_0043 GM21_3999 GM21_3999 GM21_2202 GM21_2202 GM21_2203 GM21_2203 GM21_2249 GM21_2249 GM21_2640 GM21_2640 GM21_2803 GM21_2803 GM21_2805 GM21_2805 GM21_2915 GM21_2915 GM21_2916 GM21_2916 GM21_3013 GM21_3013 GM21_3014 GM21_3014 GM21_3156 GM21_3156 GM21_3174 GM21_3174 GM21_3175 GM21_3175 GM21_3972 GM21_3972 GM21_3998 GM21_3998
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
nuoN-2Proton-translocating NADH-quinone oxidoreductase, chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (484 aa)
GM21_0159PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: gbm:Gbem_0177 NADH dehydrogenase (ubiquinone) 24 kDa subunit. (155 aa)
GM21_0673PFAM: molybdopterin oxidoreductase; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: gbm:Gbem_0660 molybdopterin oxidoreductase. (822 aa)
GM21_0690PFAM: cytochrome B561; KEGG: gbm:Gbem_0677 cytochrome b561. (244 aa)
GM21_0867KEGG: gbm:Gbem_3379 polyheme membrane-associated cytochrome c. (783 aa)
GM21_1065PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: gbm:Gbem_3197 NADH/ubiquinone/plastoquinone (complex I). (666 aa)
GM21_1069PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: gbm:Gbem_3193 NADH/ubiquinone/plastoquinone (complex I). (659 aa)
GM21_1070KEGG: gbm:Gbem_3191 NAD-dependent dehydrogenase subunit. (302 aa)
GM21_1071KEGG: gbm:Gbem_3190 NAD-dependent dehydrogenase subunit. (213 aa)
GM21_1072PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: gbm:Gbem_3189 NADH/ubiquinone/plastoquinone (complex I). (477 aa)
GM21_1126PFAM: nickel-dependent hydrogenase large subunit; KEGG: gbm:Gbem_3136 nickel-dependent hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (559 aa)
nuoK1NADH-ubiquinone oxidoreductase chain 4L; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (102 aa)
GM21_4115PFAM: Cytochrome b/b6 domain; KEGG: gbm:Gbem_4024 cytochrome b/b6 domain protein. (206 aa)
GM21_4114KEGG: gbm:Gbem_4023 hypothetical protein. (138 aa)
GM21_4006PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: gbm:Gbem_3922 NADH dehydrogenase (ubiquinone) 24 kDa subunit. (168 aa)
GM21_4004PFAM: molybdopterin oxidoreductase; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: gbm:Gbem_3920 molybdopterin oxidoreductase. (821 aa)
nuoK2NADH-ubiquinone oxidoreductase chain 4L; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (100 aa)
GM21_0151TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; KEGG: gbm:Gbem_0169 proton-translocating NADH-quinone oxidoreductase, chain L. (623 aa)
GM21_0150TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: gbm:Gbem_0168 proton-translocating NADH-quinone oxidoreductase, chain M. (495 aa)
nuoNProton-translocating NADH-quinone oxidoreductase, chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (463 aa)
GM21_0077KEGG: gbm:Gbem_0095 hypothetical protein. (616 aa)
GM21_0043PFAM: cytochrome c oxidase subunit III; KEGG: gbm:Gbem_0044 cytochrome c oxidase subunit III. (199 aa)
GM21_3999KEGG: gbm:Gbem_3915 proton-translocating NADH-quinone oxidoreductase, chain L; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein. (667 aa)
GM21_2202PFAM: cytochrome bd ubiquinol oxidase subunit II; KEGG: gbm:Gbem_2017 cytochrome bd ubiquinol oxidase subunit II. (349 aa)
GM21_2203PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: gbm:Gbem_2016 cytochrome bd ubiquinol oxidase subunit I. (441 aa)
GM21_2249PFAM: nickel-dependent hydrogenase large subunit; KEGG: gbm:Gbem_1968 nickel-dependent hydrogenase large subunit. (423 aa)
GM21_2640TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: gbm:Gbem_1573 formate dehydrogenase, gamma subunit. (204 aa)
GM21_2803PFAM: ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_1451 ferredoxin. (214 aa)
GM21_2805PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: gbm:Gbem_1449 NADH dehydrogenase (ubiquinone) 24 kDa subunit. (152 aa)
GM21_2915PFAM: nickel-dependent hydrogenase large subunit; KEGG: gbm:Gbem_1368 nickel-dependent hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (571 aa)
GM21_2916PFAM: cytochrome B561; KEGG: gbm:Gbem_1367 cytochrome b561. (390 aa)
GM21_3013TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; KEGG: gbm:Gbem_1270 cytochrome d ubiquinol oxidase, subunit II. (342 aa)
GM21_3014PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: gbm:Gbem_1269 cytochrome bd ubiquinol oxidase subunit I. (447 aa)
GM21_3156Hypothetical protein; KEGG: gsu:GSU2737 polyheme membrane-associated cytochrome c. (946 aa)
GM21_3174Cytochrome b/b6 domain protein; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (367 aa)
GM21_3175KEGG: gbm:Gbem_1086 cytochrome c family protein. (266 aa)
GM21_3972PFAM: nickel-dependent hydrogenase large subunit; KEGG: gbm:Gbem_3884 nickel-dependent hydrogenase large subunit. (473 aa)
GM21_3998KEGG: gbm:Gbem_3914 proton-translocating NADH-quinone oxidoreductase, chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I). (535 aa)
Your Current Organism:
Geobacter sp. M21
NCBI taxonomy Id: 443144
Other names: G. sp. M21
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