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GM21_0141 GM21_0141 mqnE mqnE lipA lipA GM21_0560 GM21_0560 GM21_0076 GM21_0076 GM21_0014 GM21_0014 rimO rimO GM21_0664 GM21_0664 miaB miaB GM21_0859 GM21_0859 GM21_0944 GM21_0944 GM21_1061 GM21_1061 GM21_1162 GM21_1162 GM21_1614 GM21_1614 GM21_1648 GM21_1648 GM21_1761 GM21_1761 moaA moaA GM21_2135 GM21_2135 bioB bioB GM21_2523 GM21_2523 GM21_2570 GM21_2570 moaA-2 moaA-2 GM21_2870 GM21_2870 moaA-3 moaA-3 GM21_3231 GM21_3231 GM21_3236 GM21_3236 GM21_3346 GM21_3346 GM21_3364 GM21_3364 GM21_3382 GM21_3382 GM21_3533 GM21_3533 GM21_3535 GM21_3535 GM21_3552 GM21_3552 GM21_3553 GM21_3553 GM21_3555 GM21_3555 GM21_3556 GM21_3556 GM21_3577 GM21_3577 GM21_3853 GM21_3853
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GM21_0141PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gbm:Gbem_0158 radical SAM domain protein. (828 aa)
mqnERadical SAM domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (358 aa)
lipALipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (291 aa)
GM21_0560PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gbm:Gbem_0548 radical SAM domain protein. (557 aa)
GM21_0076PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gbm:Gbem_0093 radical SAM domain protein. (616 aa)
GM21_0014PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gbm:Gbem_0015 radical SAM domain protein. (358 aa)
rimOMiaB-like tRNA modifying enzyme YliG; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (448 aa)
GM21_0664KEGG: gbm:Gbem_0651 conserved hypothetical radical SAM protein; TIGRFAM: conserved hypothetical protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (318 aa)
miaBtRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (441 aa)
GM21_0859PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gbm:Gbem_3387 radical SAM domain protein. (557 aa)
GM21_0944PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gbm:Gbem_3304 radical SAM domain protein. (488 aa)
GM21_1061PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gbm:Gbem_3202 radical SAM domain protein. (343 aa)
GM21_1162PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gbm:Gbem_3100 radical SAM domain protein. (295 aa)
GM21_1614PFAM: Radical SAM domain protein; KEGG: gbm:Gbem_2615 radical SAM domain protein. (471 aa)
GM21_1648PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: ppd:Ppro_3338 glycosyl transferase family protein. (450 aa)
GM21_1761PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gbm:Gbem_2456 radical SAM domain protein. (337 aa)
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (326 aa)
GM21_2135PFAM: Radical SAM domain protein; KEGG: gbm:Gbem_2083 radical SAM domain protein. (285 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (328 aa)
GM21_2523PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gbm:Gbem_1699 radical SAM domain protein. (424 aa)
GM21_2570KEGG: gbm:Gbem_1643 MiaB-like tRNA modifying enzyme; TIGRFAM: MiaB-like tRNA modifying enzyme; RNA modification enzyme, MiaB family; PFAM: Protein of unknown function UPF0004; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (429 aa)
moaA-2Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (326 aa)
GM21_2870PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gbm:Gbem_1410 radical SAM domain protein. (373 aa)
moaA-3Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (326 aa)
GM21_3231PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gbm:Gbem_1029 radical SAM domain protein. (472 aa)
GM21_3236PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gbm:Gbem_1024 radical SAM domain protein. (462 aa)
GM21_3346PFAM: Radical SAM domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gbm:Gbem_0915 radical SAM domain protein. (598 aa)
GM21_3364PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Elongator protein 3/MiaB/NifB; Tetratricopeptide domain protein; KEGG: gbm:Gbem_0897 radical SAM domain protein. (564 aa)
GM21_3382KEGG: gbm:Gbem_0878 hopanoid biosynthesis associated radical SAM protein HpnJ; TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnJ; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (473 aa)
GM21_3533PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gbm:Gbem_1165 radical SAM domain protein. (506 aa)
GM21_3535PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gbm:Gbem_1163 radical SAM domain protein. (444 aa)
GM21_3552PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: geo:Geob_0066 radical SAM domain protein. (488 aa)
GM21_3553PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: geo:Geob_0066 radical SAM domain protein. (474 aa)
GM21_3555PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: geo:Geob_0058 radical SAM domain protein. (448 aa)
GM21_3556PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: geo:Geob_0058 radical SAM domain protein. (450 aa)
GM21_3577Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (381 aa)
GM21_3853KEGG: gbm:Gbem_3769 conserved hypothetical radical SAM protein; TIGRFAM: conserved hypothetical protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (311 aa)
Your Current Organism:
Geobacter sp. M21
NCBI taxonomy Id: 443144
Other names: G. sp. M21
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