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uvrB uvrB priA priA GM21_0169 GM21_0169 mfd mfd GM21_0420 GM21_0420 GM21_0430 GM21_0430 GM21_0821 GM21_0821 GM21_0954 GM21_0954 GM21_1010 GM21_1010 GM21_4133 GM21_4133 GM21_3854 GM21_3854 GM21_3785 GM21_3785 GM21_3707 GM21_3707 secA secA recG recG GM21_1748 GM21_1748 GM21_1744 GM21_1744 GM21_1455 GM21_1455 GM21_1180 GM21_1180 GM21_1247 GM21_1247 rhlB rhlB
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
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gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
uvrBExcinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (662 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (752 aa)
GM21_0169PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: gbm:Gbem_0187 DEAD/DEAH box helicase domain protein; Belongs to the DEAD box helicase family. (449 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1157 aa)
GM21_0420PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: gur:Gura_0598 non-specific serine/threonine protein kinase. (901 aa)
GM21_0430Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1030 aa)
GM21_0821PFAM: type III restriction protein res subunit; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: gsu:GSU1359 helicase, putative. (1042 aa)
GM21_0954PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: gbm:Gbem_3293 DEAD/DEAH box helicase domain protein. (453 aa)
GM21_1010PFAM: SNF2-related protein; restriction endonuclease; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: bpt:Bpet0222 helicase, putative. (1248 aa)
GM21_4133PFAM: DEAD_2 domain protein; SMART: helicase c2; Helicase-like, DEXD box c2 type; KEGG: gbm:Gbem_4042 DEAD_2 domain protein. (798 aa)
GM21_3854SMART: helicase c2; DEAD-like helicase; KEGG: gbm:Gbem_3770 helicase C2. (830 aa)
GM21_3785KEGG: gbm:Gbem_3690 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; HRDC domain protein; SMART: helicase domain protein; HRDC domain protein; DEAD-like helicase. (599 aa)
GM21_3707PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: gbm:Gbem_3598 DEAD/DEAH box helicase domain protein; Belongs to the DEAD box helicase family. (381 aa)
secAPreprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (957 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (772 aa)
GM21_1748PFAM: SNF2-related protein; zinc finger SWIM domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: gbm:Gbem_2469 SNF2-related protein. (1120 aa)
GM21_1744PFAM: SNF2-related protein; helicase domain protein; SMART: helicase domain protein; DEAD-like helicase; KEGG: gbm:Gbem_2473 SNF2-related protein. (1386 aa)
GM21_1455PFAM: DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicase; KEGG: ajs:Ajs_2426 DEAD/DEAH box helicase domain-containing protein. (430 aa)
GM21_1180KEGG: gbm:Gbem_3081 ATP-dependent helicase HrpB; TIGRFAM: ATP-dependent helicase HrpB; PFAM: Helicase ATP-dependent domain protein; helicase-associated domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein. (828 aa)
GM21_1247PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: bxe:Bxe_B0141 DEAD/DEAH box helicase. (743 aa)
rhlBDEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. (490 aa)
Your Current Organism:
Geobacter sp. M21
NCBI taxonomy Id: 443144
Other names: G. sp. M21
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