STRINGSTRING
mnmA-2 mnmA-2 coaD coaD GM21_2469 GM21_2469 GM21_2552 GM21_2552 valS valS GM21_2705 GM21_2705 GM21_2715 GM21_2715 GM21_2716 GM21_2716 GM21_2783 GM21_2783 GM21_2133 GM21_2133 GM21_2132 GM21_2132 GM21_2106 GM21_2106 gltX gltX argS argS GM21_1925 GM21_1925 cysD cysD GM21_3180 GM21_3180 GM21_1627 GM21_1627 tilS tilS GM21_1384 GM21_1384 hldE hldE tyrS tyrS GM21_0065 GM21_0065 GM21_0342 GM21_0342 ttcA ttcA leuS leuS guaA guaA GM21_1383 GM21_1383 gluQ gluQ panC panC GM21_3947 GM21_3947 cysS cysS glnS glnS nadD nadD queC queC ileS ileS argG argG GM21_2784 GM21_2784 GM21_2786 GM21_2786 GM21_2787 GM21_2787 GM21_2927 GM21_2927 GM21_2928 GM21_2928 GM21_2949 GM21_2949 nadE-2 nadE-2 GM21_2950 GM21_2950 nadE nadE GM21_0790 GM21_0790 mnmA mnmA GM21_1055 GM21_1055 metG metG GM21_1863 GM21_1863 GM21_1847 GM21_1847
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mnmA-2tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (359 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (161 aa)
GM21_2469TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; KEGG: gbm:Gbem_1778 asparagine synthase (glutamine-hydrolyzing). (629 aa)
GM21_2552PFAM: UspA domain protein; KEGG: gbm:Gbem_1661 UspA domain protein. (147 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (888 aa)
GM21_2705PFAM: UspA domain protein; KEGG: gbm:Gbem_1511 UspA domain protein. (151 aa)
GM21_2715PFAM: Electron transfer flavoprotein alpha subunit; Electron transfer flavoprotein alpha/beta-subunit; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_1501 electron transfer flavoprotein alpha subunit. (439 aa)
GM21_2716PFAM: Electron transfer flavoprotein alpha/beta-subunit; KEGG: gbm:Gbem_1500 electron transfer flavoprotein alpha/beta-subunit. (270 aa)
GM21_2783PFAM: Electron transfer flavoprotein alpha subunit; Electron transfer flavoprotein alpha/beta-subunit; KEGG: gbm:Gbem_1470 electron transfer flavoprotein alpha subunit. (302 aa)
GM21_2133PFAM: Electron transfer flavoprotein alpha/beta-subunit; KEGG: gbm:Gbem_2085 electron transfer flavoprotein alpha/beta-subunit. (270 aa)
GM21_2132PFAM: Electron transfer flavoprotein alpha subunit; Electron transfer flavoprotein alpha/beta-subunit; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_2086 electron transfer flavoprotein alpha subunit. (436 aa)
GM21_2106PFAM: UspA domain protein; KEGG: gbm:Gbem_2112 UspA domain protein. (160 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (467 aa)
argSKEGG: gbm:Gbem_2283 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. (554 aa)
GM21_1925KEGG: gbm:Gbem_2298 tryptophanyl-tRNA synthetase; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib. (327 aa)
cysDTIGRFAM: sulfate adenylyltransferase, small subunit; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: gbm:Gbem_2353 sulfate adenylyltransferase, small subunit. (301 aa)
GM21_3180TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; KEGG: gbm:Gbem_1081 asparagine synthase (glutamine-hydrolyzing). (660 aa)
GM21_1627TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; KEGG: gbm:Gbem_2599 riboflavin biosynthesis protein RibF; Belongs to the ribF family. (323 aa)
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (457 aa)
GM21_1384PFAM: Electron transfer flavoprotein alpha subunit; Electron transfer flavoprotein alpha/beta-subunit; KEGG: gbm:Gbem_2829 electron transfer flavoprotein alpha subunit. (305 aa)
hldErfaE bifunctional protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (487 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (403 aa)
GM21_0065PFAM: thiamine biosynthesis protein; KEGG: gbm:Gbem_0082 thiamine biosynthesis protein. (334 aa)
GM21_0342KEGG: gbm:Gbem_0361 PP-loop domain protein. (268 aa)
ttcAPP-loop domain protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (255 aa)
leuSTIGRFAM: leucyl-tRNA synthetase; KEGG: gbm:Gbem_0751 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (824 aa)
guaAGMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (516 aa)
GM21_1383PFAM: Electron transfer flavoprotein alpha/beta-subunit; KEGG: gbm:Gbem_2830 electron transfer flavoprotein alpha/beta-subunit. (260 aa)
gluQglutamyl-tRNA synthetase class Ic; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (310 aa)
panCPantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (279 aa)
GM21_3947KEGG: gbm:Gbem_3862 citrate lyase ligase; TIGRFAM: citrate lyase ligase; cytidyltransferase-related domain protein; PFAM: Citrate lyase ligase domain protein; cytidylyltransferase; SMART: Citrate lyase ligase domain protein. (333 aa)
cysSKEGG: gbm:Gbem_3800 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Belongs to the class-I aminoacyl-tRNA synthetase family. (480 aa)
glnSTIGRFAM: glutaminyl-tRNA synthetase; PFAM: glutamyl-tRNA synthetase class Ic; KEGG: gbm:Gbem_3799 glutaminyl-tRNA synthetase. (565 aa)
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (216 aa)
queCexsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (225 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (925 aa)
argGKEGG: gbm:Gbem_3638 argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (406 aa)
GM21_2784PFAM: Electron transfer flavoprotein alpha/beta-subunit; KEGG: gbm:Gbem_1469 electron transfer flavoprotein alpha/beta-subunit. (258 aa)
GM21_2786PFAM: Electron transfer flavoprotein alpha subunit; Electron transfer flavoprotein alpha/beta-subunit; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_1467 electron transfer flavoprotein alpha subunit. (447 aa)
GM21_2787PFAM: Electron transfer flavoprotein alpha/beta-subunit; KEGG: gbm:Gbem_1466 electron transfer flavoprotein alpha/beta-subunit. (270 aa)
GM21_2927PFAM: Electron transfer flavoprotein alpha subunit; Electron transfer flavoprotein alpha/beta-subunit; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_1358 electron transfer flavoprotein alpha subunit. (452 aa)
GM21_2928PFAM: Electron transfer flavoprotein alpha/beta-subunit; KEGG: gbm:Gbem_1357 electron transfer flavoprotein alpha/beta-subunit. (270 aa)
GM21_2949PFAM: Electron transfer flavoprotein alpha subunit; Electron transfer flavoprotein alpha/beta-subunit; KEGG: gbm:Gbem_1334 electron transfer flavoprotein alpha subunit. (303 aa)
nadE-2NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (273 aa)
GM21_2950PFAM: Electron transfer flavoprotein alpha/beta-subunit; KEGG: gbm:Gbem_1333 electron transfer flavoprotein alpha/beta-subunit. (258 aa)
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (328 aa)
GM21_0790PFAM: phosphoadenosine phosphosulfate reductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mmw:Mmwyl1_2969 phosphoadenosine phosphosulfate reductase. (784 aa)
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (355 aa)
GM21_1055PFAM: protein of unknown function DUF218; KEGG: gbm:Gbem_3208 protein of unknown function DUF218. (195 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (509 aa)
GM21_1863Phosphoadenylyl-sulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. (230 aa)
GM21_1847PFAM: UspA domain protein; KEGG: gbm:Gbem_2372 UspA domain protein. (293 aa)
Your Current Organism:
Geobacter sp. M21
NCBI taxonomy Id: 443144
Other names: G. sp. M21
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.