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GM21_0192 GM21_0192 sucD sucD sucC sucC GM21_0258 GM21_0258 pdhA pdhA GM21_0476 GM21_0476 GM21_0477 GM21_0477 GM21_0716 GM21_0716 GM21_0717 GM21_0717 GM21_0718 GM21_0718 pckA pckA pckG pckG GM21_0912 GM21_0912 GM21_0913 GM21_0913 GM21_0914 GM21_0914 sucC-2 sucC-2 sucD-2 sucD-2 GM21_1174 GM21_1174 GM21_1175 GM21_1175 GM21_1176 GM21_1176 GM21_1177 GM21_1177 GM21_1324 GM21_1324 mdh mdh GM21_1326 GM21_1326 GM21_1327 GM21_1327 GM21_1328 GM21_1328 GM21_1329 GM21_1329 GM21_1966 GM21_1966 pdhA-2 pdhA-2 GM21_1974 GM21_1974 GM21_2050 GM21_2050 GM21_2561 GM21_2561 sucD-3 sucD-3 sucC-3 sucC-3 GM21_2989 GM21_2989 GM21_3371 GM21_3371 GM21_3566 GM21_3566 GM21_3990 GM21_3990 GM21_4125 GM21_4125 GM21_4127 GM21_4127
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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GM21_0192TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_0209 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (1183 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (298 aa)
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa)
GM21_0258Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1148 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (351 aa)
GM21_0476PFAM: Transketolase central region; Transketolase domain protein; KEGG: gbm:Gbem_0460 transketolase central region. (320 aa)
GM21_0477PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: gbm:Gbem_0461 catalytic domain of components of various dehydrogenase complexes. (405 aa)
GM21_0716KEGG: gbm:Gbem_0704 2-oxoglutarate dehydrogenase, E1 subunit; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component. (896 aa)
GM21_07172-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (419 aa)
GM21_0718TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: gme:Gmet_2764 dihydrolipoamide dehydrogenase. (470 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (529 aa)
pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (647 aa)
GM21_0912TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; KEGG: gbm:Gbem_3334 succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family. (221 aa)
GM21_0913KEGG: gbm:Gbem_3333 succinate dehydrogenase or fumarate reductase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein. (637 aa)
GM21_0914PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_3332 4Fe-4S ferredoxin iron-sulfur binding domain protein. (246 aa)
sucC-2succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)
sucD-2succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
GM21_1174PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_3087 4Fe-4S ferredoxin iron-sulfur binding domain protein. (67 aa)
GM21_1175PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: gbm:Gbem_3086 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (356 aa)
GM21_1176PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: gbm:Gbem_3085 thiamine pyrophosphate protein domain protein TPP-binding. (246 aa)
GM21_1177TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: gbm:Gbem_3084 pyruvate/ketoisovalerate oxidoreductase, gamma subunit. (183 aa)
GM21_1324KEGG: gbm:Gbem_2901 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent monomeric type; Belongs to the monomeric-type IDH family. (743 aa)
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (317 aa)
GM21_1326PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_2899 4Fe-4S ferredoxin iron-sulfur binding domain protein. (64 aa)
GM21_1327PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: gbm:Gbem_2898 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (377 aa)
GM21_1328PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: gbm:Gbem_2897 thiamine pyrophosphate protein domain protein TPP-binding. (270 aa)
GM21_1329PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: gbm:Gbem_2896 pyruvate ferredoxin/flavodoxin oxidoreductase. (182 aa)
GM21_1966TIGRFAM: aconitate hydratase; PFAM: aconitate hydratase domain protein; KEGG: gbm:Gbem_2258 aconitate hydratase. (648 aa)
pdhA-2Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (325 aa)
GM21_1974PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: gbm:Gbem_2250 catalytic domain of components of various dehydrogenase complexes. (486 aa)
GM21_2050Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (934 aa)
GM21_2561PFAM: Citrate synthase; KEGG: gbm:Gbem_1652 citrate synthase; Belongs to the citrate synthase family. (441 aa)
sucD-3succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (308 aa)
sucC-3succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (392 aa)
GM21_2989TIGRFAM: aconitate hydratase 2; PFAM: Aconitase B, N-terminal; aconitate hydratase domain protein; KEGG: gbm:Gbem_1294 aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. (839 aa)
GM21_3371Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (541 aa)
GM21_3566PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: gme:Gmet_1896 dihydrolipoamide dehydrogenase. (452 aa)
GM21_3990PFAM: Citrate synthase; KEGG: gbm:Gbem_3905 citrate synthase; Belongs to the citrate synthase family. (454 aa)
GM21_4125TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_4034 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (1238 aa)
GM21_4127KEGG: gbm:Gbem_4036 flavocytochrome c; TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; HI0933 family protein; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (598 aa)
Your Current Organism:
Geobacter sp. M21
NCBI taxonomy Id: 443144
Other names: G. sp. M21
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