node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GM21_1378 | GM21_2794 | GM21_1378 | GM21_2794 | KEGG: gbm:Gbem_2835 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: gbm:Gbem_1460 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.901 |
GM21_1489 | GM21_3026 | GM21_1489 | GM21_3026 | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | PFAM: Polyprenyl synthetase; KEGG: gbm:Gbem_1257 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.963 |
GM21_1489 | GM21_3477 | GM21_1489 | GM21_3477 | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: gbm:Gbem_3415 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.965 |
GM21_1489 | dxr | GM21_1489 | GM21_1491 | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.937 |
GM21_2794 | GM21_1378 | GM21_2794 | GM21_1378 | TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: gbm:Gbem_1460 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | KEGG: gbm:Gbem_2835 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.901 |
GM21_3026 | GM21_1489 | GM21_3026 | GM21_1489 | PFAM: Polyprenyl synthetase; KEGG: gbm:Gbem_1257 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.963 |
GM21_3026 | GM21_3477 | GM21_3026 | GM21_3477 | PFAM: Polyprenyl synthetase; KEGG: gbm:Gbem_1257 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: gbm:Gbem_3415 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.921 |
GM21_3026 | dxr | GM21_3026 | GM21_1491 | PFAM: Polyprenyl synthetase; KEGG: gbm:Gbem_1257 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.488 |
GM21_3026 | dxs | GM21_3026 | GM21_0883 | PFAM: Polyprenyl synthetase; KEGG: gbm:Gbem_1257 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.543 |
GM21_3026 | dxs-2 | GM21_3026 | GM21_3025 | PFAM: Polyprenyl synthetase; KEGG: gbm:Gbem_1257 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.892 |
GM21_3026 | ispE | GM21_3026 | GM21_1446 | PFAM: Polyprenyl synthetase; KEGG: gbm:Gbem_1257 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.439 |
GM21_3026 | ispH | GM21_3026 | GM21_0994 | PFAM: Polyprenyl synthetase; KEGG: gbm:Gbem_1257 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.932 |
GM21_3477 | GM21_1489 | GM21_3477 | GM21_1489 | Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: gbm:Gbem_3415 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.965 |
GM21_3477 | GM21_3026 | GM21_3477 | GM21_3026 | Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: gbm:Gbem_3415 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | PFAM: Polyprenyl synthetase; KEGG: gbm:Gbem_1257 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.921 |
GM21_3477 | dxr | GM21_3477 | GM21_1491 | Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: gbm:Gbem_3415 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.501 |
GM21_3477 | ispD | GM21_3477 | GM21_3880 | Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: gbm:Gbem_3415 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.410 |
GM21_3477 | ispE | GM21_3477 | GM21_1446 | Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: gbm:Gbem_3415 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.482 |
GM21_3477 | ispF | GM21_3477 | GM21_3881 | Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: gbm:Gbem_3415 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.410 |
GM21_3477 | ispG | GM21_3477 | GM21_1333 | Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: gbm:Gbem_3415 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.455 |
GM21_3477 | ispH | GM21_3477 | GM21_0994 | Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: gbm:Gbem_3415 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.469 |