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| | GM21_0029 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_0030 4Fe-4S ferredoxin iron-sulfur binding domain protein. (665 aa) |
| | GM21_0030 | CoB--CoM heterodisulfide reductase; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: gbm:Gbem_0031 protein of unknown function DUF224 cysteine-rich region domain protein. (317 aa) |
| | GM21_0031 | KEGG: gbm:Gbem_0032 heterodisulfide reductase subunit. (194 aa) |
| | GM21_0192 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_0209 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (1183 aa) |
| | GM21_0209 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (912 aa) |
| | sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (298 aa) |
| | sucC | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa) |
| | GM21_0258 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1148 aa) |
| | GM21_0264 | PFAM: Transketolase domain protein; KEGG: gbm:Gbem_0279 transketolase domain protein. (274 aa) |
| | GM21_0265 | PFAM: Transketolase central region; Transketolase domain protein; KEGG: gbm:Gbem_0280 transketolase central region. (310 aa) |
| | GM21_0304 | KEGG: gbm:Gbem_0312 aldehyde ferredoxin oxidoreductase; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase. (600 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (409 aa) |
| | GM21_0389 | TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: gbm:Gbem_0395 glycine cleavage system T protein. (363 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (123 aa) |
| | gcvPA | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (445 aa) |
| | GM21_0392 | Glycine dehydrogenase (decarboxylating); PFAM: glycine cleavage system P-protein; KEGG: gbm:Gbem_0398 glycine dehydrogenase (decarboxylating). (479 aa) |
| | pdhA | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (351 aa) |
| | GM21_0476 | PFAM: Transketolase central region; Transketolase domain protein; KEGG: gbm:Gbem_0460 transketolase central region. (320 aa) |
| | GM21_0477 | PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: gbm:Gbem_0461 catalytic domain of components of various dehydrogenase complexes. (405 aa) |
| | GM21_0478 | Glutamate dehydrogenase (NAD(P)(+)); PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: gur:Gura_2895 Glu/Leu/Phe/Val dehydrogenase, C terminal; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (363 aa) |
| | GM21_0571 | TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: gbm:Gbem_0558 methylmalonyl-CoA epimerase. (137 aa) |
| | GM21_0572 | KEGG: gur:Gura_0654 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase. (550 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (214 aa) |
| | GM21_0657 | KEGG: gbm:Gbem_0644 pyruvate, phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; Belongs to the PEP-utilizing enzyme family. (914 aa) |
| | GM21_0672 | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: gbm:Gbem_0659 FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (670 aa) |
| | GM21_0673 | PFAM: molybdopterin oxidoreductase; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: gbm:Gbem_0660 molybdopterin oxidoreductase. (822 aa) |
| | GM21_0678 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_0665 4Fe-4S ferredoxin iron-sulfur binding domain protein. (302 aa) |
| | GM21_0716 | KEGG: gbm:Gbem_0704 2-oxoglutarate dehydrogenase, E1 subunit; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component. (896 aa) |
| | GM21_0717 | 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (419 aa) |
| | GM21_0718 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: gme:Gmet_2764 dihydrolipoamide dehydrogenase. (470 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (529 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (282 aa) |
| | GM21_0904 | KEGG: gbm:Gbem_3341 aldehyde ferredoxin oxidoreductase; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase. (579 aa) |
| | GM21_0912 | TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; KEGG: gbm:Gbem_3334 succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family. (221 aa) |
| | GM21_0913 | KEGG: gbm:Gbem_3333 succinate dehydrogenase or fumarate reductase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein. (637 aa) |
| | GM21_0914 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_3332 4Fe-4S ferredoxin iron-sulfur binding domain protein. (246 aa) |
| | GM21_0946 | PFAM: methylenetetrahydrofolate reductase; KEGG: gbm:Gbem_3302 methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (291 aa) |
| | GM21_1031 | KEGG: gbm:Gbem_3234 1-phosphofructokinase; TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; Belongs to the carbohydrate kinase PfkB family. (311 aa) |
| | sucC-2 | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa) |
| | sucD-2 | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa) |
| | GM21_1159 | KEGG: gbm:Gbem_3103 sugar-phosphate isomerase, RpiB/LacA/LacB family; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase. (151 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa) |
| | GM21_1174 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_3087 4Fe-4S ferredoxin iron-sulfur binding domain protein. (67 aa) |
| | GM21_1175 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: gbm:Gbem_3086 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (356 aa) |
| | GM21_1176 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: gbm:Gbem_3085 thiamine pyrophosphate protein domain protein TPP-binding. (246 aa) |
| | GM21_1177 | TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: gbm:Gbem_3084 pyruvate/ketoisovalerate oxidoreductase, gamma subunit. (183 aa) |
| | pfkA | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (361 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (290 aa) |
| | GM21_1324 | KEGG: gbm:Gbem_2901 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent monomeric type; Belongs to the monomeric-type IDH family. (743 aa) |
| | mdh | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (317 aa) |
| | GM21_1326 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_2899 4Fe-4S ferredoxin iron-sulfur binding domain protein. (64 aa) |
| | GM21_1327 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: gbm:Gbem_2898 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (377 aa) |
| | GM21_1328 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: gbm:Gbem_2897 thiamine pyrophosphate protein domain protein TPP-binding. (270 aa) |
| | GM21_1329 | PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: gbm:Gbem_2896 pyruvate ferredoxin/flavodoxin oxidoreductase. (182 aa) |
| | GM21_1378 | KEGG: gbm:Gbem_2835 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa) |
| | GM21_1379 | PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: gbm:Gbem_2834 3-hydroxyacyl-CoA dehydrogenase NAD-binding. (281 aa) |
| | GM21_1380 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: gbm:Gbem_2833 enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa) |
| | GM21_1381 | PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: gbm:Gbem_2832 acyl-CoA dehydrogenase domain protein. (379 aa) |
| | GM21_1392 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (390 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (316 aa) |
| | GM21_1548 | PFAM: cobalamin B12-binding domain protein; KEGG: gbm:Gbem_2691 cobalamin B12-binding domain protein. (134 aa) |
| | GM21_1609 | KEGG: gbm:Gbem_2620 aldehyde ferredoxin oxidoreductase; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase. (656 aa) |
| | pfkA-2 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa) |
| | fbp | Fructose-bisphosphatase; PFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: gbm:Gbem_2410 inositol phosphatase/fructose-16-bisphosphatase. (326 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa) |
| | pgk | PFAM: phosphoglycerate kinase; KEGG: gbm:Gbem_2337 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (399 aa) |
| | GM21_1884 | KEGG: gbm:Gbem_2336 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (331 aa) |
| | ackA-2 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (421 aa) |
| | GM21_1947 | KEGG: gbm:Gbem_2276 phosphate acetyltransferase; TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase. (333 aa) |
| | GM21_1956 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_2266 4Fe-4S ferredoxin iron-sulfur binding domain protein. (278 aa) |
| | GM21_1966 | TIGRFAM: aconitate hydratase; PFAM: aconitate hydratase domain protein; KEGG: gbm:Gbem_2258 aconitate hydratase. (648 aa) |
| | pdhA-2 | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (325 aa) |
| | GM21_1974 | PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: gbm:Gbem_2250 catalytic domain of components of various dehydrogenase complexes. (486 aa) |
| | GM21_2050 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (934 aa) |
| | GM21_2092 | PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: gbm:Gbem_2126 3-hydroxyacyl-CoA dehydrogenase NAD-binding. (789 aa) |
| | glk | Glucokinase; KEGG: gbm:Gbem_2002 glucokinase; TIGRFAM: glucokinase; PFAM: Glucokinase; ROK family protein; Belongs to the bacterial glucokinase family. (327 aa) |
| | GM21_2237 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: gbm:Gbem_1983 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. (317 aa) |
| | GM21_2256 | TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein; KEGG: gbm:Gbem_1961 D-3-phosphoglycerate dehydrogenase. (532 aa) |
| | GM21_2321 | PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase; KEGG: gbm:Gbem_1888 malic protein. (749 aa) |
| | GM21_2331 | KEGG: gbm:Gbem_1879 putative homoserine kinase; TIGRFAM: proposed homoserine kinase; phosphonopyruvate decarboxylase-related protein; PFAM: metalloenzyme domain protein. (399 aa) |
| | GM21_2468 | KEGG: gbm:Gbem_1779 transferase hexapeptide repeat containing protein. (175 aa) |
| | GM21_2515 | PFAM: Aldehyde Dehydrogenase; KEGG: gbm:Gbem_1707 aldehyde dehydrogenase. (539 aa) |
| | GM21_2561 | PFAM: Citrate synthase; KEGG: gbm:Gbem_1652 citrate synthase; Belongs to the citrate synthase family. (441 aa) |
| | GM21_2565 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: gbm:Gbem_1648 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding. (321 aa) |
| | GM21_2569 | TIGRFAM: serine O-acetyltransferase; KEGG: gbm:Gbem_1644 serine O-acetyltransferase. (222 aa) |
| | GM21_2638 | Contains selenocysteine; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: gur:Gura_3374 formate dehydrogenase, alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1059 aa) |
| | GM21_2639 | PFAM: Formate dehydrogenase transmembrane domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_1574 formate dehydrogenase transmembrane domain protein. (263 aa) |
| | GM21_2640 | TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: gbm:Gbem_1573 formate dehydrogenase, gamma subunit. (204 aa) |
| | gcvH-2 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa) |
| | GM21_2654 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (446 aa) |
| | GM21_2655 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (157 aa) |
| | folD-2 | Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (281 aa) |
| | sucD-3 | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (308 aa) |
| | sucC-3 | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (392 aa) |
| | GM21_2792 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: gbm:Gbem_1462 enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (259 aa) |
| | GM21_2793 | PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: gbm:Gbem_1461 3-hydroxyacyl-CoA dehydrogenase NAD-binding. (282 aa) |
| | GM21_2794 | TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: gbm:Gbem_1460 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa) |
| | GM21_2798 | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic protein NAD-binding; malic protein domain protein; KEGG: gbm:Gbem_1455 malic protein. (780 aa) |
| | GM21_2806 | Contains selenocysteine; PFAM: methyl-viologen-reducing hydrogenase delta subunit; KEGG: gbm:Gbem_1448 methyl-viologen-reducing hydrogenase delta subunit. (255 aa) |
| | GM21_2807 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_1447 4Fe-4S ferredoxin iron-sulfur binding domain protein. (1012 aa) |
| | GM21_2815 | PFAM: acetyl-CoA hydrolase/transferase; KEGG: gbm:Gbem_1439 acetyl-CoA hydrolase/transferase. (437 aa) |
| | GM21_2842 | KEGG: geo:Geob_0113 aldehyde ferredoxin oxidoreductase; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase. (575 aa) |
| | GM21_2863 | PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: gbm:Gbem_1417 3-hydroxyacyl-CoA dehydrogenase NAD-binding. (288 aa) |
| | tal-2 | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (374 aa) |
| | GM21_2903 | TIGRFAM: transketolase; PFAM: Transketolase central region; Transketolase domain protein; KEGG: gbm:Gbem_1379 transketolase; Belongs to the transketolase family. (711 aa) |
| | GM21_2933 | KEGG: gbm:Gbem_1352 aldehyde ferredoxin oxidoreductase; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase. (576 aa) |
| | GM21_2957 | PFAM: ROK family protein; KEGG: gbm:Gbem_1326 ROK family protein. (306 aa) |
| | GM21_2959 | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase; PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase; KEGG: gbm:Gbem_1324 malic protein. (749 aa) |
| | GM21_2989 | TIGRFAM: aconitate hydratase 2; PFAM: Aconitase B, N-terminal; aconitate hydratase domain protein; KEGG: gbm:Gbem_1294 aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. (839 aa) |
| | GM21_3052 | PFAM: formylmethanofuran dehydrogenase subunit E region; KEGG: gbm:Gbem_1223 formylmethanofuran dehydrogenase subunit E-like protein. (185 aa) |
| | GM21_3093 | KEGG: gbm:Gbem_1182 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. (481 aa) |
| | GM21_3253 | PFAM: ketose-bisphosphate aldolase class-II; KEGG: gbm:Gbem_1007 fructose/tagatose bisphosphate aldolase-like protein. (427 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa) |
| | GM21_3278 | KEGG: gbm:Gbem_0982 BioD-like protein N-terminal domain of phosphotransacetylase-like protein. (364 aa) |
| | GM21_3371 | Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (541 aa) |
| | GM21_3397 | PFAM: Transketolase central region; Transketolase domain protein; KEGG: bbt:BBta_5637 transketolase subunit B. (298 aa) |
| | GM21_3398 | PFAM: Transketolase domain protein; KEGG: bbt:BBta_5636 transketolase subunit A. (263 aa) |
| | pgi | PFAM: phosphoglucose isomerase (PGI); KEGG: gbm:Gbem_3417 phosphoglucose isomerase (PGI); Belongs to the GPI family. (530 aa) |
| | GM21_3566 | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: gme:Gmet_1896 dihydrolipoamide dehydrogenase. (452 aa) |
| | gpmA | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (234 aa) |
| | GM21_3593 | KEGG: gbm:Gbem_3527 ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (221 aa) |
| | GM21_3717 | Hydroxypyruvate reductase; PFAM: MOFRL domain protein; KEGG: gbm:Gbem_3609 MOFRL domain protein. (420 aa) |
| | GM21_3784 | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: gbm:Gbem_3689 threonine dehydratase. (402 aa) |
| | gpmI | Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (512 aa) |
| | GM21_3873 | KEGG: gbm:Gbem_3789 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (480 aa) |
| | GM21_3972 | PFAM: nickel-dependent hydrogenase large subunit; KEGG: gbm:Gbem_3884 nickel-dependent hydrogenase large subunit. (473 aa) |
| | GM21_3973 | PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: gbm:Gbem_3885 NADH ubiquinone oxidoreductase 20 kDa subunit. (315 aa) |
| | GM21_3990 | PFAM: Citrate synthase; KEGG: gbm:Gbem_3905 citrate synthase; Belongs to the citrate synthase family. (454 aa) |
| | GM21_4125 | TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gbm:Gbem_4034 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (1238 aa) |
| | GM21_4127 | KEGG: gbm:Gbem_4036 flavocytochrome c; TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; HI0933 family protein; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (598 aa) |
