STRINGSTRING
EDM45937.1 EDM45937.1 EDM45938.1 EDM45938.1 EDM47402.1 EDM47402.1 EDM47403.1 EDM47403.1 EDM47404.1 EDM47404.1 EDM47457.1 EDM47457.1 lptC lptC EDM48781.1 EDM48781.1 EDM48787.1 EDM48787.1 EDM48834.1 EDM48834.1 EDM46542.1 EDM46542.1 EDM46544.1 EDM46544.1 secB secB EDM48339.1 EDM48339.1 EDM48406.1 EDM48406.1 tatA tatA tatB tatB tatC tatC EDM45975.1 EDM45975.1 EDM47859.1 EDM47859.1 EDM48961.1 EDM48961.1 EDM49239.1 EDM49239.1 EDM49240.1 EDM49240.1 EDM49241.1 EDM49241.1 EDM49242.1 EDM49242.1 EDM49243.1 EDM49243.1 EDM49244.1 EDM49244.1 EDM49245.1 EDM49245.1 EDM49246.1 EDM49246.1 EDM49247.1 EDM49247.1 EDM49248.1 EDM49248.1 secF secF secD secD yajC yajC ftsB ftsB EDM46715.1 EDM46715.1 EDM49524.1 EDM49524.1 EDM49611.1 EDM49611.1 EDM49706.1 EDM49706.1 EDM49707.1 EDM49707.1 ffh ffh secA secA EDM46950.1 EDM46950.1 clpB clpB EDM46432.1 EDM46432.1 EDM46433.1 EDM46433.1 EDM46437.1 EDM46437.1 EDM46438.1 EDM46438.1 EDM46439.1 EDM46439.1 EDM46870.1 EDM46870.1 EDM46873.1 EDM46873.1 EDM46874.1 EDM46874.1 EDM46899.1 EDM46899.1 EDM46262.1 EDM46262.1 EDM47478.1 EDM47478.1 EDM47479.1 EDM47479.1 EDM47480.1 EDM47480.1 EDM47481.1 EDM47481.1 EDM47482.1 EDM47482.1 EDM47484.1 EDM47484.1 EDM47485.1 EDM47485.1 EDM47488.1 EDM47488.1 EDM47490.1 EDM47490.1 EDM47491.1 EDM47491.1 EDM47492.1 EDM47492.1 secY secY secE secE EDM48622.1 EDM48622.1 EDM46357.1 EDM46357.1 yidC yidC EDM48560.1 EDM48560.1 ftsY ftsY EDM45881.1 EDM45881.1 EDM45882.1 EDM45882.1 EDM45884.1 EDM45884.1 EDM45885.1 EDM45885.1 EDM46600.1 EDM46600.1 EDM46601.1 EDM46601.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EDM45937.1COG1450 Type II secretory pathway, component PulD. (650 aa)
EDM45938.1General secretion pathway protein C; COG3031 Type II secretory pathway, component PulC. (283 aa)
EDM47402.1COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB. (571 aa)
EDM47403.1COG1459 Type II secretory pathway, component PulF. (406 aa)
EDM47404.1Type II secretory pathway, prepilin signal peptidase PulO and related peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. (291 aa)
EDM47457.1Predicted metal-binding protein; Similar to the C-terminal domain of SecA; COG3318 Predicted metal-binding protein related to the C-terminal domain of SecA; Belongs to the UPF0149 family. (179 aa)
lptCHypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. (196 aa)
EDM48781.1COG0631 Serine/threonine protein phosphatase. (572 aa)
EDM48787.1Transglycosylase SLT domain protein; COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains). (233 aa)
EDM48834.1SEC-C motif domain protein; COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase). (114 aa)
EDM46542.1Type I secretion membrane fusion protein, HlyD; COG0845 Membrane-fusion protein. (388 aa)
EDM46544.1COG1538 Outer membrane protein. (387 aa)
secBProtein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (166 aa)
EDM48339.1Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (126 aa)
EDM48406.1Rhs element Vgr protein. (694 aa)
tatASec-independent protein secretion pathway component; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (78 aa)
tatBTwin-arginine translocation protein TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (171 aa)
tatCSec-independent protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (264 aa)
EDM45975.1Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein. (261 aa)
EDM47859.1COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. (756 aa)
EDM48961.1Hypothetical protein. (391 aa)
EDM49239.1Type II secretory pathway, component PulM; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (177 aa)
EDM49240.1Type II secretory pathway, component PulL; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (434 aa)
EDM49241.1COG3156 Type II secretory pathway, component PulK. (337 aa)
EDM49242.1General secretion pathway protein J; COG4795 Type II secretory pathway, component PulJ. (242 aa)
EDM49243.1General secretion pathway protein I; COG2165 Type II secretory pathway, pseudopilin PulG. (124 aa)
EDM49244.1General secretion pathway protein H; COG2165 Type II secretory pathway, pseudopilin PulG. (184 aa)
EDM49245.1General secretion pathway protein G; COG2165 Type II secretory pathway, pseudopilin PulG. (150 aa)
EDM49246.1General secretion pathway protein F; COG1459 Type II secretory pathway, component PulF. (403 aa)
EDM49247.1Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (504 aa)
EDM49248.1Hypothetical protein; COG3031 Type II secretory pathway, component PulC. (220 aa)
secFProtein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (318 aa)
secDProtein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (624 aa)
yajCPreprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (120 aa)
ftsBSeptum formation initiator; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (90 aa)
EDM46715.1COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB. (600 aa)
EDM49524.1Hypothetical protein. (305 aa)
EDM49611.1VgrG protein; COG3501 Uncharacterized protein conserved in bacteria. (691 aa)
EDM49706.1COG0631 Serine/threonine protein phosphatase. (247 aa)
EDM49707.1COG0515 Serine/threonine protein kinase. (552 aa)
ffhSignal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] (462 aa)
secAPreprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (917 aa)
EDM46950.1COG0631 Serine/threonine protein phosphatase. (571 aa)
clpBATPase with chaperone activity, ATP-binding subunit; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (858 aa)
EDM46432.1COG4970 Tfp pilus assembly protein FimT. (185 aa)
EDM46433.1General secretion pathway protein H; COG4968 Tfp pilus assembly protein PilE. (149 aa)
EDM46437.1COG4966 Tfp pilus assembly protein PilW. (364 aa)
EDM46438.1Type IV fimbrial biogenesis protein PilV; COG4967 Tfp pilus assembly protein PilV. (182 aa)
EDM46439.1Putative type-4 fimbrial pilin related signal peptide protein; COG4970 Tfp pilus assembly protein FimT. (201 aa)
EDM46870.1Type 4 fimbrial biogenesis protein PilQ; COG4796 Type II secretory pathway, component HofQ. (694 aa)
EDM46873.1COG3166 Tfp pilus assembly protein PilN. (187 aa)
EDM46874.1COG4972 Tfp pilus assembly protein, ATPase PilM. (354 aa)
EDM46899.1VgrG protein; COG3501 Uncharacterized protein conserved in bacteria. (706 aa)
EDM46262.1COG1538 Outer membrane protein. (459 aa)
EDM47478.1Hypothetical protein. (259 aa)
EDM47479.1Hypothetical protein. (166 aa)
EDM47480.1COG2165 Type II secretory pathway, pseudopilin PulG. (141 aa)
EDM47481.1COG2165 Type II secretory pathway, pseudopilin PulG. (159 aa)
EDM47482.1Pilin, putative. (172 aa)
EDM47484.1COG1459 Type II secretory pathway, component PulF. (409 aa)
EDM47485.1COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB. (598 aa)
EDM47488.1COG1450 Type II secretory pathway, component PulD. (578 aa)
EDM47490.1COG0845 Membrane-fusion protein. (232 aa)
EDM47491.1Methionine sulfoxide reductase B; COG0542 ATPases with chaperone activity, ATP-binding subunit. (202 aa)
EDM47492.1Hypothetical protein. (302 aa)
secYProtein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (440 aa)
secEPreprotein translocase SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (122 aa)
EDM48622.1COG3012 Uncharacterized protein conserved in bacteria. (114 aa)
EDM46357.1COG3157 Hemolysin-coregulated protein (uncharacterized). (172 aa)
yidCPreprotein translocase subunit YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (570 aa)
EDM48560.1Chaperone-associated ATPase, putative; COG0542 ATPases with chaperone activity, ATP-binding subunit. (347 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (400 aa)
EDM45881.1Hypothetical protein; COG3456 Uncharacterized conserved protein, contains FHA domain. (444 aa)
EDM45882.1COG3521 Uncharacterized protein conserved in bacteria. (177 aa)
EDM45884.1COG3455 Uncharacterized protein conserved in bacteria. (275 aa)
EDM45885.1clpB protein; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. (880 aa)
EDM46600.1COG3523 Uncharacterized protein conserved in bacteria. (1194 aa)
EDM46601.1VgrG protein; COG3501 Uncharacterized protein conserved in bacteria. (693 aa)
Your Current Organism:
Marinobacter algicola
NCBI taxonomy Id: 443152
Other names: M. algicola DG893, Marinobacter algicola DG893, Marinobacter algicola str. DG893, Marinobacter algicola strain DG893, Marinobacter sp. DG893
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