Groups of genes that are frequently observed in each other's genomic neighborhood.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CPSG_01272
Guanylate kinase. (175 aa)
CPSG_01273
GRIP domain-containing protein. (548 aa)
CPSG_02776
CASP family protein. (740 aa)
CPSG_06583
Uncharacterized protein. (538 aa)
CPSG_08452
E3 ubiquitin-protein ligase HUWE1. (1173 aa)
Your Current Organism:
Coccidioides posadasii
NCBI taxonomy Id: 443226 Other names: C. posadasii str. Silveira, Coccidioides posadasii str. Silveira