12 items (Streptomyces sp. CNQ509) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AKH85028.1	3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (539 aa)
	AKH85212.1	Kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (750 aa)
	glnD	protein-PII uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (949 aa)
	AKH81361.1	GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (832 aa)
	AKH81643.1	Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
	AKH82661.1	Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
	purU	Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (282 aa)
	AKH83265.1	Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (423 aa)
	AKH83414.1	Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
	AKH84486.1	Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
	AKH84884.1	Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
	AKH85026.1	Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)

Your Current Organism:

Streptomyces sp. CNQ509

NCBI taxonomy Id: 444103
Other names: S. sp. CNQ-509, Streptomyces sp. CNQ-509

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKH81361.1	AKH85212.1	AA958_03265	AA958_26620	GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	Kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.912
AKH81643.1	AKH83414.1	AA958_04910	AA958_15720	Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.963
AKH81643.1	AKH84884.1	AA958_04910	AA958_24780	Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.536
AKH82661.1	AKH85026.1	AA958_10960	AA958_25560	Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.826
AKH82661.1	purU	AA958_10960	AA958_12970	Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).	0.800
AKH83265.1	AKH83414.1	AA958_14675	AA958_15720	Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family.	Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.457
AKH83265.1	AKH84884.1	AA958_14675	AA958_24780	Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family.	Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.964
AKH83265.1	AKH85028.1	AA958_14675	AA958_25570	Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family.	3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.403
AKH83414.1	AKH81643.1	AA958_15720	AA958_04910	Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.963
AKH83414.1	AKH83265.1	AA958_15720	AA958_14675	Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family.	0.457
AKH83414.1	AKH84884.1	AA958_15720	AA958_24780	Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.445
AKH83414.1	AKH85026.1	AA958_15720	AA958_25560	Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.789
AKH84486.1	AKH84884.1	AA958_22360	AA958_24780	Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology.	Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.535
AKH84486.1	AKH85026.1	AA958_22360	AA958_25560	Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.971
AKH84486.1	AKH85028.1	AA958_22360	AA958_25570	Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.449
AKH84884.1	AKH81643.1	AA958_24780	AA958_04910	Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.536
AKH84884.1	AKH83265.1	AA958_24780	AA958_14675	Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family.	0.964
AKH84884.1	AKH83414.1	AA958_24780	AA958_15720	Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.445
AKH84884.1	AKH84486.1	AA958_24780	AA958_22360	Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.535
AKH84884.1	AKH85026.1	AA958_24780	AA958_25560	Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.882