STRINGSTRING
hisH hisH carA carA AKH86169.1 AKH86169.1 cnq728 cnq728 pyrG pyrG AKH84774.1 AKH84774.1 guaA guaA AKH83510.1 AKH83510.1 AKH86584.1 AKH86584.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (222 aa)
carACarbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (389 aa)
AKH86169.1Aminobenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (709 aa)
cnq728Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (671 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (583 aa)
AKH84774.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (524 aa)
AKH83510.1Aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
AKH86584.1Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (629 aa)
Your Current Organism:
Streptomyces sp. CNQ509
NCBI taxonomy Id: 444103
Other names: S. sp. CNQ-509, Streptomyces sp. CNQ-509
Server load: low (28%) [HD]