(39 nodes) Class I glutamine amidotransferase-like network (Streptomyces sp. CNQ509)

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	AKH83510.1	Aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
	purQ	Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (226 aa)
	AKH83947.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
	AKH86910.1	AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
	AKH84141.1	AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
	guaA	GMP synthase; Catalyzes the synthesis of GMP from XMP. (524 aa)
	AKH84473.1	AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
	AKH84503.1	AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
	cnq728	Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (671 aa)
	AKH85806.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
	AKH85722.1	Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
	AKH87095.1	Glycosyl hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)
	AKH84774.1	Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
	AKH85326.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (66 aa)
	AKH85560.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (992 aa)
	AKH86220.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
	AKH86169.1	Aminobenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (709 aa)
	AKH86078.1	Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)
	AKH80948.1	Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
	AKH81272.1	Sugar-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1151 aa)
	AKH81314.1	Beta-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (664 aa)
	carA	Carbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (389 aa)
	pdxT	Glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (197 aa)
	AKH81469.1	Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
	AKH81623.1	AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
	pyrG	CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (583 aa)
	cobQ	Cobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (509 aa)
	cobB	Cobyrinic acid ac-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (514 aa)
	hisH	Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (222 aa)
	AKH86584.1	Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (629 aa)
	AKH82094.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1048 aa)
	AKH82095.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
	AKH82097.1	Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
	AKH82247.1	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (782 aa)
	AKH82364.1	AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
	AKH86666.1	AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
	AKH82631.1	AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (359 aa)
	AKH86729.1	AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
	AKH83160.1	Glycosyl hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1034 aa)

Your Current Organism:

Streptomyces sp. CNQ509

NCBI taxonomy Id: 444103
Other names: S. sp. CNQ-509, Streptomyces sp. CNQ-509

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKH81314.1	pdxT	AA958_03005	AA958_03310	Beta-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.	0.424
AKH82094.1	AKH82095.1	AA958_07460	AA958_07465	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.415
AKH82094.1	AKH83160.1	AA958_07460	AA958_13975	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycosyl hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.920
AKH82095.1	AKH82094.1	AA958_07465	AA958_07460	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.415
AKH82095.1	AKH82097.1	AA958_07465	AA958_07475	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.816
AKH82097.1	AKH82095.1	AA958_07475	AA958_07465	Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.816
AKH83160.1	AKH82094.1	AA958_13975	AA958_07460	Glycosyl hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.920
AKH83510.1	AKH86169.1	AA958_16300	AA958_32560	Aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aminobenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.977
AKH83510.1	AKH86584.1	AA958_16300	AA958_06685	Aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology.	Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.777
AKH83510.1	cnq728	AA958_16300	AA958_30775	Aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology.	Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.793
AKH83947.1	AKH85560.1	AA958_19075	AA958_28685	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.638
AKH84774.1	guaA	AA958_24040	AA958_21610	Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.922
AKH85560.1	AKH83947.1	AA958_28685	AA958_19075	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.638
AKH86169.1	AKH83510.1	AA958_32560	AA958_16300	Aminobenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.977
AKH86169.1	AKH86584.1	AA958_32560	AA958_06685	Aminobenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.993
AKH86169.1	cnq728	AA958_32560	AA958_30775	Aminobenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.993
AKH86169.1	guaA	AA958_32560	AA958_21610	Aminobenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.583
AKH86169.1	hisH	AA958_32560	AA958_06375	Aminobenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.	0.449
AKH86584.1	AKH83510.1	AA958_06685	AA958_16300	Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.777
AKH86584.1	AKH86169.1	AA958_06685	AA958_32560	Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aminobenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.993