STRINGSTRING
AKH81358.1 AKH81358.1 AKH81564.1 AKH81564.1 AKH81591.1 AKH81591.1 AKH81833.1 AKH81833.1 AKH81996.1 AKH81996.1 AKH82002.1 AKH82002.1 AKH82206.1 AKH82206.1 AKH82348.1 AKH82348.1 leuA leuA AKH82558.1 AKH82558.1 AKH82661.1 AKH82661.1 AKH82769.1 AKH82769.1 ppc ppc AKH82924.1 AKH82924.1 AKH83133.1 AKH83133.1 acsA acsA AKH83535.1 AKH83535.1 AKH83536.1 AKH83536.1 AKH86825.1 AKH86825.1 AKH83547.1 AKH83547.1 AKH83548.1 AKH83548.1 AKH86826.1 AKH86826.1 AKH83740.1 AKH83740.1 AKH84210.1 AKH84210.1 AKH84211.1 AKH84211.1 mdh mdh AKH84446.1 AKH84446.1 AKH84458.1 AKH84458.1 pckG pckG aspA aspA AKH84539.1 AKH84539.1 AKH84579.1 AKH84579.1 AKH84733.1 AKH84733.1 AKH84923.1 AKH84923.1 AKH84942.1 AKH84942.1 ackA ackA AKH84944.1 AKH84944.1 AKH85040.1 AKH85040.1 AKH85077.1 AKH85077.1 AKH85454.1 AKH85454.1 AKH85498.1 AKH85498.1 AKH85518.1 AKH85518.1 AKH85731.1 AKH85731.1 AKH86088.1 AKH86088.1 AKH86179.1 AKH86179.1 AKH86213.1 AKH86213.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKH81358.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
AKH81564.1Pyruvate dehydrogenase; Catalyzes the formation of acetate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (580 aa)
AKH81591.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (472 aa)
AKH81833.1Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
AKH81996.1Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
AKH82002.1Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (897 aa)
AKH82206.1Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (915 aa)
AKH82348.1Pyruvate phosphate dikinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. (952 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (588 aa)
AKH82558.1acetyl-COA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (759 aa)
AKH82661.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
AKH82769.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (411 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (930 aa)
AKH82924.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (446 aa)
AKH83133.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (485 aa)
acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa)
AKH83535.1Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
AKH83536.12-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
AKH86825.1Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (514 aa)
AKH83547.1Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
AKH83548.12-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
AKH86826.1Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (522 aa)
AKH83740.12-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (338 aa)
AKH84210.12-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
AKH84211.12-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (629 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (332 aa)
AKH84446.1Betaine-aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (480 aa)
AKH84458.1acetyl-COA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (585 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (602 aa)
aspAAspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (478 aa)
AKH84539.1Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (569 aa)
AKH84579.1Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)
AKH84733.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
AKH84923.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
AKH84942.1Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (402 aa)
AKH84944.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (719 aa)
AKH85040.1Transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (542 aa)
AKH85077.1Acylphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (93 aa)
AKH85454.1Lactate 2-monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
AKH85498.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (557 aa)
AKH85518.1Malate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family. (532 aa)
AKH85731.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
AKH86088.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (411 aa)
AKH86179.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa)
AKH86213.1Thiamine pyrophosphate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (600 aa)
Your Current Organism:
Streptomyces sp. CNQ509
NCBI taxonomy Id: 444103
Other names: S. sp. CNQ-509, Streptomyces sp. CNQ-509
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