(15 nodes) rRNA-binding, and Translation protein SH3-like domain superfamily network (Methanococcus maripaludis C6)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rpl7ae	Ribosomal protein L7Ae/L30e/S12e/Gadd45; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (136 aa)
	rpl24e	Ribosomal protein L24E; Binds to the 23S rRNA. (62 aa)
	rpl14e	KOW motif; KEGG: mvn:Mevan_1498 KOW motif; Belongs to the eukaryotic ribosomal protein eL14 family. (77 aa)
	rpl21e	PFAM: Ribosomal protein L21e; KEGG: mvn:Mevan_1105 ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family. (97 aa)
	rpl23	Ribosomal protein L25/L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (86 aa)
	rpl15	Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (143 aa)
	rpl18	Ribosomal protein L18P/L5E; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (193 aa)
	rpl19e	Ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (149 aa)
	rpl32e	PFAM: Ribosomal protein L32e; KEGG: mvn:Mevan_0727 ribosomal protein L32e; Belongs to the eukaryotic ribosomal protein eL32 family. (135 aa)
	rpl6	Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (182 aa)
	rpl5	Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (181 aa)
	rpl14	Ribosomal protein L14b/L23e; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (132 aa)
	rpl29	PFAM: ribosomal protein L29; KEGG: mvn:Mevan_0716 ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (68 aa)
	rpl22	Ribosomal protein L22; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (153 aa)
	rpl13	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (137 aa)

Your Current Organism:

Methanococcus maripaludis C6

NCBI taxonomy Id: 444158
Other names: M. maripaludis C6, Methanococcus maripaludis str. C6, Methanococcus maripaludis strain C6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
rpl13	rpl14	MmarC6_1349	MmarC6_1264	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Ribosomal protein L14b/L23e; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	0.999
rpl13	rpl14e	MmarC6_1349	MmarC6_0266	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	KOW motif; KEGG: mvn:Mevan_1498 KOW motif; Belongs to the eukaryotic ribosomal protein eL14 family.	0.998
rpl13	rpl15	MmarC6_1349	MmarC6_1252	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.999
rpl13	rpl18	MmarC6_1349	MmarC6_1255	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Ribosomal protein L18P/L5E; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.	0.999
rpl13	rpl19e	MmarC6_1349	MmarC6_1256	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.	0.999
rpl13	rpl21e	MmarC6_1349	MmarC6_0854	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	PFAM: Ribosomal protein L21e; KEGG: mvn:Mevan_1105 ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.	0.999
rpl13	rpl22	MmarC6_1349	MmarC6_1270	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Ribosomal protein L22; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.	0.999
rpl13	rpl23	MmarC6_1349	MmarC6_1125	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Ribosomal protein L25/L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.	0.999
rpl13	rpl24e	MmarC6_1349	MmarC6_0250	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Ribosomal protein L24E; Binds to the 23S rRNA.	0.999
rpl13	rpl29	MmarC6_1349	MmarC6_1268	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	PFAM: ribosomal protein L29; KEGG: mvn:Mevan_0716 ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.	0.999
rpl13	rpl32e	MmarC6_1349	MmarC6_1257	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	PFAM: Ribosomal protein L32e; KEGG: mvn:Mevan_0727 ribosomal protein L32e; Belongs to the eukaryotic ribosomal protein eL32 family.	0.999
rpl13	rpl5	MmarC6_1349	MmarC6_1261	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.	0.999
rpl13	rpl6	MmarC6_1349	MmarC6_1258	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.	0.999
rpl13	rpl7ae	MmarC6_1349	MmarC6_0248	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Ribosomal protein L7Ae/L30e/S12e/Gadd45; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.	0.998
rpl14	rpl13	MmarC6_1264	MmarC6_1349	Ribosomal protein L14b/L23e; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.999
rpl14	rpl14e	MmarC6_1264	MmarC6_0266	Ribosomal protein L14b/L23e; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	KOW motif; KEGG: mvn:Mevan_1498 KOW motif; Belongs to the eukaryotic ribosomal protein eL14 family.	0.999
rpl14	rpl15	MmarC6_1264	MmarC6_1252	Ribosomal protein L14b/L23e; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.999
rpl14	rpl18	MmarC6_1264	MmarC6_1255	Ribosomal protein L14b/L23e; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	Ribosomal protein L18P/L5E; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.	0.999
rpl14	rpl19e	MmarC6_1264	MmarC6_1256	Ribosomal protein L14b/L23e; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	Ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.	0.999
rpl14	rpl21e	MmarC6_1264	MmarC6_0854	Ribosomal protein L14b/L23e; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	PFAM: Ribosomal protein L21e; KEGG: mvn:Mevan_1105 ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.	0.998