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| | ABX01118.1 | Soluble liver antigen/liver pancreas antigen; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. Belongs to the SepSecS family. (436 aa) |
| | ABX02631.1 | PFAM: ribonuclease H; KEGG: mvn:Mevan_1622 ribonuclease H. (201 aa) |
| | rnp2 | Ribonuclease P-related; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (130 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec); Belongs to the class-II aminoacyl-tRNA synthetase family. Type-2 seryl-tRNA synthetase subfamily. (514 aa) |
| | ABX02568.1 | KEGG: mvn:Mevan_0022 ATP/GTP-binding site motif A (P-loop). (219 aa) |
| | ABX02567.1 | SMART: Rhodanese domain protein; KEGG: mvn:Mevan_0021 rhodanese domain protein. (217 aa) |
| | rnz | Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (308 aa) |
| | rnp4 | RNAse P, Rpr2/Rpp21 subunit; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (110 aa) |
| | trmY | Protein of unknown function DUF358; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family. (198 aa) |
| | cca | tRNA cytidylyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (459 aa) |
| | ABX02500.1 | PFAM: Protein of unknown function DUF509; KEGG: mvn:Mevan_0290 protein of unknown function DUF509. (143 aa) |
| | rsmA | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (263 aa) |
| | dtdA | Protein of unknown function DUF516; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo. (254 aa) |
| | ABX02461.1 | KEGG: mvn:Mevan_0337 pseudouridine synthase, RluA family; TIGRFAM: pseudouridine synthase, RluA family; PFAM: pseudouridine synthase. (297 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (555 aa) |
| | ABX02457.1 | PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mvn:Mevan_0342 radical SAM domain protein. (355 aa) |
| | argS | KEGG: mvn:Mevan_0350 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (566 aa) |
| | rlmH | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. (159 aa) |
| | ABX02433.1 | KEGG: mvn:Mevan_0361 A1A0 ATPase, subunit H. (102 aa) |
| | ABX02420.1 | PFAM: protein of unknown function DUF88; KEGG: mvn:Mevan_0373 protein of unknown function DUF88. (215 aa) |
| | cysS | KEGG: mvn:Mevan_0382 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia. (476 aa) |
| | ABX02377.1 | SMART: phospholipase D/Transphosphatidylase; KEGG: mvn:Mevan_0427 phospholipase D/transphosphatidylase. (191 aa) |
| | ABX02353.1 | TIGRFAM: RNA methylase, NOL1/NOP2/sun family; PFAM: Fmu (Sun) domain protein; KEGG: mvn:Mevan_0449 putative RNA methylase, NOL1/NOP2/sun family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (275 aa) |
| | endA | tRNA intron endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. (176 aa) |
| | ABX02334.1 | PFAM: Like-Sm ribonucleoprotein core; SMART: Sm-family ribonucleoprotein; KEGG: mvn:Mevan_0470 like-Sm ribonucleoprotein core. (72 aa) |
| | ABX02284.1 | PFAM: protein of unknown function UPF0066; KEGG: mvn:Mevan_0517 protein of unknown function UPF0066. (127 aa) |
| | ABX02254.1 | PP-loop domain protein; PFAM: protein of unknown function DUF71 ATP-binding region; PP-loop domain protein; KEGG: mvn:Mevan_0546 thiamine biosynthesis protein. (296 aa) |
| | ABX02246.1 | Sep-tRNA; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family. (380 aa) |
| | pheT | KEGG: mvn:Mevan_0569 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5. (554 aa) |
| | dnaG | TOPRIM domain protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (438 aa) |
| | fen | XPG I domain protein; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. [...] (324 aa) |
| | lysS | KEGG: mvn:Mevan_0629 lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: Lysyl-tRNA synthetase class 1c; Belongs to the class-I aminoacyl-tRNA synthetase family. (533 aa) |
| | ABX02164.1 | PFAM: RNA polymerase dimerisation; RNA polymerase insert; SMART: RNA polymerase RpoA/D/Rpb3-type; KEGG: mvn:Mevan_0633 RNA polymerase insert. (180 aa) |
| | rpoN | RNA polymerase, N/8 Kd subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. (68 aa) |
| | ABX02159.1 | PFAM: RNA polymerase Rpb6; KEGG: mvn:Mevan_0638 RNA polymerase Rpb6. (59 aa) |
| | ABX02147.1 | PFAM: protein of unknown function DUF890; KEGG: mvn:Mevan_0650 protein of unknown function DUF890. (293 aa) |
| | ABX02144.1 | PFAM: PilT protein domain protein; Protein of unknown function DUF652; SMART: Nucleotide binding protein PINc; KEGG: mvn:Mevan_0653 nucleotide binding protein PINc. (131 aa) |
| | ABX02139.1 | PFAM: Transcription factor CBF/NF-Y/histone domain protein; Histone core domain protein; KEGG: mvn:Mevan_0658 transcription factor CBF/NF-Y histone. (66 aa) |
| | ABX02133.1 | PFAM: PP-loop domain protein; KEGG: mvn:Mevan_0175 PP-loop domain protein. (324 aa) |
| | thiI | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (383 aa) |
| | ABX02130.1 | PFAM: PP-loop domain protein; KEGG: mvn:Mevan_0666 PP-loop domain protein. (311 aa) |
| | rpoH | RNA polymerase Rpb5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (78 aa) |
| | ABX02125.1 | PFAM: RNA polymerase Rpb2 domain 2; RNA polymerase beta subunit; RNA polymerase Rpb2 domain 3; KEGG: mvn:Mevan_0671 RNA polymerase beta subunit; Belongs to the RNA polymerase beta chain family. (499 aa) |
| | ABX02124.1 | RNA polymerase Rpb2 domain 6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (611 aa) |
| | ABX02123.1 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (889 aa) |
| | rpoA2 | DNA-directed RNA polymerase, subunit A'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (386 aa) |
| | nusA | NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family. (173 aa) |
| | rnhB | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (239 aa) |
| | ABX02111.1 | PFAM: tRNA methyltransferase complex GCD14 subunit; KEGG: mvn:Mevan_0685 tRNA methyltransferase complex GCD14 subunit. (290 aa) |
| | rtcB | PFAM: protein of unknown function UPF0027; KEGG: mvn:Mevan_0703 protein of unknown function UPF0027; Belongs to the RtcB family. (480 aa) |
| | rnp1 | Ribonuclease P, Rpp29; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family. (98 aa) |
| | ABX02061.1 | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. (179 aa) |
| | ABX02057.1 | TIGRFAM: transcription factor S; PFAM: Transcription factor TFIIS; DNA-directed RNA polymerase, M/15 kDa subunit; KEGG: mvn:Mevan_0740 transcription termination factor Tfs; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (105 aa) |
| | taw1 | Wyosine base formation domain protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (313 aa) |
| | ABX02014.1 | Protein of unknown function UPF0278; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family. (223 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1034 aa) |
| | ABX01997.1 | PFAM: Chromatin associated protein KTI12; KEGG: mvn:Mevan_0799 chromatin associated protein KTI12. (264 aa) |
| | pheS | TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase class IIc; KEGG: mvn:Mevan_0805 phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (502 aa) |
| | ABX01957.1 | PFAM: ribonuclease III; double-stranded RNA binding domain protein; KEGG: mvn:Mevan_0839 ribonuclease III. (229 aa) |
| | ABX01942.1 | PFAM: Translin; KEGG: mvn:Mevan_0856 translin. (196 aa) |
| | ABX01907.1 | KEGG: mvn:Mevan_0889 histone acetyltransferase, ELP3 family; TIGRFAM: histone acetyltransferase, ELP3 family; PFAM: GCN5-related N-acetyltransferase; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (541 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). (358 aa) |
| | ABX01891.1 | TIGRFAM: methanogenesis marker protein 11; PFAM: domain of unknown function DUF1743; KEGG: mvn:Mevan_0905 domain of unknown function DUF1743. (301 aa) |
| | ABX01889.1 | PFAM: PUA domain containing protein; KEGG: mvn:Mevan_0907 PUA domain containing protein. (538 aa) |
| | hisS | KEGG: mvn:Mevan_0924 histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; Belongs to the class-II aminoacyl-tRNA synthetase family. (418 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (438 aa) |
| | truB | rRNA pseudouridine synthase; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (333 aa) |
| | nop10 | RNA-binding protein Nop10p; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (51 aa) |
| | ABX01762.1 | TIGRFAM: L-seryl-tRNA selenium transferase; KEGG: mvn:Mevan_1219 L-seryl-tRNA selenium transferase. (354 aa) |
| | priL | DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (369 aa) |
| | ABX01750.1 | PFAM: tRNA pseudouridine synthase D TruD; KEGG: mvn:Mevan_1207 tRNA pseudouridine synthase D TruD. (389 aa) |
| | tfe | Transcription factor TFIIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongatio [...] (185 aa) |
| | ABX01727.1 | KEGG: mvn:Mevan_1034 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region. (194 aa) |
| | tfb | Transcription factor TFIIB cyclin-related; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (339 aa) |
| | ABX01722.1 | KEGG: mvn:Mevan_1057 hypothetical protein. (93 aa) |
| | rnj | Beta-lactamase domain protein; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily. (448 aa) |
| | priS | DNA primase, small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] (357 aa) |
| | pelA | Translation factor pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (348 aa) |
| | ABX01678.1 | DNA binding protein, Tfx family; Putative transcriptional regulator. (147 aa) |
| | ABX01672.1 | PFAM: RNA polymerase Rpb4; KEGG: mvn:Mevan_1104 RNA polymerase Rpb4. (107 aa) |
| | pus10 | THUMP domain protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. (470 aa) |
| | ABX01640.1 | PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: mvn:Mevan_1134 PHP domain protein. (239 aa) |
| | ABX01635.1 | PFAM: Sjogrens syndrome scleroderma autoantigen 1; KEGG: mvn:Mevan_1139 Sjogrens syndrome scleroderma autoantigen 1. (112 aa) |
| | ABX01618.1 | PFAM: putative RNA methylase; THUMP domain protein; KEGG: mvn:Mevan_1154 putative RNA methylase. (351 aa) |
| | ABX01617.1 | Protein of unknown function DUF367; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family. (171 aa) |
| | ABX01612.1 | PFAM: protein of unknown function UPF0044; KEGG: mvn:Mevan_1160 protein of unknown function UPF0044. (127 aa) |
| | ABX01583.1 | TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: mvn:Mevan_1188 SUA5/YciO/YrdC/YwlC family protein. (206 aa) |
| | glyS | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). (574 aa) |
| | trm1 | N2,N2-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (373 aa) |
| | ABX01540.1 | KEGG: mvn:Mevan_1243 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region. (228 aa) |
| | ABX01524.1 | KEGG: mvn:Mevan_1259 hypothetical protein. (83 aa) |
| | ABX01523.1 | Brix domain protein; Probably involved in the biogenesis of the ribosome. (164 aa) |
| | ABX01522.1 | SMART: RNA polymerase Rbp10; KEGG: mvn:Mevan_1261 RNA polymerase Rbp10. (46 aa) |
| | ABX01515.1 | PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: mvn:Mevan_1268 PHP domain protein. (299 aa) |
| | tbp | TATA-box binding family protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (181 aa) |
| | rpoL | RNA polymerase dimerisation; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. (96 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (311 aa) |
| | truA | tRNA pseudouridine synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. (262 aa) |
| | ABX01004.1 | PFAM: protein of unknown function DUF752; KEGG: mvn:Mevan_1581 protein of unknown function DUF752. (340 aa) |
| | leuS | TIGRFAM: leucyl-tRNA synthetase; KEGG: mvn:Mevan_1575 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (955 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (460 aa) |
| | sepS | O-phosphoseryl-tRNA(Cys) synthetase; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys). (537 aa) |
| | ABX01046.1 | KEGG: mvn:Mevan_1529 putative ATP binding related protein. (291 aa) |
| | ABX01051.1 | PFAM: amino acid-binding ACT domain protein; KEGG: mvn:Mevan_1534 ACT domain-containing protein; Belongs to the UPF0237 family. (90 aa) |
| | rtcA | RNA 3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. (337 aa) |
| | ABX01063.1 | Protein of unknown function DUF101; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. (138 aa) |
| | rpl7ae | Ribosomal protein L7Ae/L30e/S12e/Gadd45; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (136 aa) |
| | tiaS | Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (424 aa) |
| | truD | tRNA pseudouridine synthase D TruD; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (430 aa) |
| | tgtA | Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (649 aa) |
| | rlmE | Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (258 aa) |
| | ABX01108.1 | PFAM: KH type 1 domain protein; SMART: KH domain protein; KEGG: mvn:Mevan_1477 KH type 1 domain protein. (184 aa) |
| | flpA | Non-specific serine/threonine protein kinase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (230 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (886 aa) |
| | taw2 | Protein of unknown function Met10; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7- aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe). (253 aa) |
| | ABX01223.1 | PFAM: protein of unknown function UPF0066; KEGG: mem:Memar_0464 protein of unknown function UPF0066. (182 aa) |
| | ABX01289.1 | TIGRFAM: DNA-directed RNA polymerase; PFAM: RNA binding S1 domain protein; RNA polymerase Rpb7 domain protein; KEGG: mvn:Mevan_1425 DNA-directed RNA polymerase. (187 aa) |
| | ABX01291.1 | KEGG: mvn:Mevan_1423 4Fe-4S ferredoxin iron-sulfur binding domain protein. (261 aa) |
| | rnp3 | Ribonuclease P; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family. (232 aa) |
| | ABX01312.1 | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein ki [...] (543 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr); Belongs to the class-II aminoacyl-tRNA synthetase family. (622 aa) |
| | ABX01315.1 | KEGG: mvn:Mevan_1400 MiaB-like tRNA modifying enzyme; TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme; PFAM: deoxyribonuclease/rho motif-related TRAM; Radical SAM domain protein; Protein of unknown function UPF0004; SMART: Elongator protein 3/MiaB/NifB. (425 aa) |
| | ABX01321.1 | TIGRFAM: TIM-barrel protein; KEGG: mvn:Mevan_1394 putative TIM-barrel protein. (260 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (892 aa) |
| | ABX01341.1 | PFAM: Transcription factor CBF/NF-Y/histone domain protein; Histone core domain protein; KEGG: mvn:Mevan_1373 transcription factor CBF/NF-Y histone. (67 aa) |
| | ABX01350.1 | PFAM: PHP domain protein; KEGG: mvn:Mevan_1365 PHP domain protein. (214 aa) |
| | ABX01389.1 | Hypothetical protein. (267 aa) |
| | ABX01435.1 | TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: mvn:Mevan_1345 RNA methyltransferase, TrmH family, group 1. (234 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (663 aa) |
| | ABX01445.1 | PFAM: protein of unknown function Met10; KEGG: mvn:Mevan_1334 protein of unknown function Met10. (342 aa) |
| | taw3 | Protein of unknown function DUF207; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. (194 aa) |
| | ABX01459.1 | PFAM: DsrE family protein; KEGG: mja:MJ0989 putative uncharacterized protein involved in oxidation of intracellular sulfur. (114 aa) |
| | ABX01460.1 | PFAM: SirA family protein; KEGG: mvn:Mevan_1319 SirA family protein. (70 aa) |
