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| | Emin_0016 | KEGG: gur:Gura_3501 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; Belongs to the peptidase S26 family. (324 aa) |
| | alaS | Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (868 aa) |
| | Emin_0032 | TIGRFAM: signal peptide peptidase SppA, 36K type; PFAM: peptidase S49; KEGG: pth:PTH_2842 periplasmic serine proteases. (371 aa) |
| | Emin_0045 | PFAM: peptidase U62 modulator of DNA gyrase; KEGG: sus:Acid_5819 peptidase U62, modulator of DNA gyrase. (556 aa) |
| | Emin_0046 | Zn-dependent protease-like protein; KEGG: sus:Acid_5820 peptidase U62, modulator of DNA gyrase. (534 aa) |
| | lnt | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (553 aa) |
| | prfB | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (371 aa) |
| | lysS | KEGG: chy:CHY_2365 lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; Belongs to the class-II aminoacyl-tRNA synthetase family. (498 aa) |
| | Emin_0067 | Glutamyl-tRNA(Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (90 aa) |
| | gatA | Glutamyl-tRNA(Gln) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (474 aa) |
| | rpmB | PFAM: ribosomal protein L28; KEGG: dol:Dole_2056 ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family. (64 aa) |
| | gltX | Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (488 aa) |
| | rplU | Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (104 aa) |
| | Emin_0091 | PFAM: ribosomal protein L27; KEGG: tel:tsl0166 50S ribosomal protein L27. (114 aa) |
| | hprK | Serine kinase of the HPr protein, regulates carbohydrate metabolism; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). (330 aa) |
| | lepA | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (605 aa) |
| | pheS | TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; KEGG: pmy:Pmen_1980 phenylalanyl-tRNA synthetase subunit alpha; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (349 aa) |
| | pheT | KEGG: hch:HCH_04574 phenylalanyl-tRNA synthetase subunit beta; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (791 aa) |
| | Emin_0163 | Putative peptidoglycan glycosyltransferase; KEGG: dol:Dole_0135 penicillin-binding protein, 1A family; TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase. (713 aa) |
| | Emin_0165 | PFAM: LemA family protein; KEGG: dde:Dde_0577 LemA protein. (182 aa) |
| | Emin_0174 | Putative two-component system; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: tme:Tmel_1496 histidine kinase. (248 aa) |
| | glyS | KEGG: bay:RBAM_023560 GlyS; TIGRFAM: glycyl-tRNA synthetase, beta subunit. (687 aa) |
| | glyQ | KEGG: gme:Gmet_2942 glycyl-tRNA synthetase subunit alpha; TIGRFAM: glycyl-tRNA synthetase, alpha subunit; PFAM: glycyl-tRNA synthetase alpha subunit. (285 aa) |
| | rpsT | Ribosomal protein S20; Binds directly to 16S ribosomal RNA. (91 aa) |
| | leuS | TIGRFAM: leucyl-tRNA synthetase; KEGG: tde:TDE2339 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (835 aa) |
| | Emin_0236 | Type II secretion system subunit; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. (260 aa) |
| | valS | Valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (904 aa) |
| | rimO | RNA modification enzyme, MiaB family; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (430 aa) |
| | Emin_0305 | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: mms:mma_2611 signal transduction histidine kinase. (360 aa) |
| | rpsU | PFAM: ribosomal protein S21; KEGG: afw:Anae109_0759 ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. (64 aa) |
| | infC | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (177 aa) |
| | rpmI | PFAM: ribosomal protein L35; KEGG: cpr:CPR_1857 ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family. (67 aa) |
| | rplT | Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (118 aa) |
| | Emin_0354 | PFAM: peptidase M20; peptidase M42 family protein; KEGG: mba:Mbar_A0214 cellulase. (346 aa) |
| | Emin_0361 | Membrane protein implicated in regulation of membrane protease activity; PFAM: protein of unknown function DUF107; KEGG: pgi:PG1335 hypothetical protein. (141 aa) |
| | lgt | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (263 aa) |
| | Emin_0378 | PFAM: LemA family protein; KEGG: det:DET1586 LemA family protein. (185 aa) |
| | Emin_0379 | PFAM: peptidase M48 Ste24p; KEGG: bfr:BF1889 putative protease. (330 aa) |
| | lipA | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (297 aa) |
| | aspS | Aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (583 aa) |
| | hisS | KEGG: gsu:GSU1659 histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein. (410 aa) |
| | Emin_0388 | (NiFe) hydrogenase maturation protein; TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: tte:TTE0132 hydrogenase maturation factor. (71 aa) |
| | Emin_0389 | PFAM: hydrogenase formation HypD protein; KEGG: tte:TTE0133 hydrogenase maturation factor. (346 aa) |
| | Emin_0390 | TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: det:DET1435 hydrogenase expression/formation protein HypE. (335 aa) |
| | Emin_0391 | TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC domain; zinc finger HypF domain protein; KEGG: tte:TTE0131 hydrogenase maturation factor. (736 aa) |
| | greA | Transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (156 aa) |
| | lon | Endopeptidase La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (830 aa) |
| | Emin_0510 | Putative two-component system; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sth:STH1040 two-component sensor histidine kinase. (320 aa) |
| | smpB | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] (157 aa) |
| | Emin_0529 | Peptidase; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. (408 aa) |
| | Emin_0546 | PFAM: RNA binding S1 domain protein; KEGG: mta:Moth_1329 4-hydroxy-3-methylbut-2-enyl diphosphate reductase/S1 RNA-binding domain protein. (399 aa) |
| | thrS | TIGRFAM: threonyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; Threonyl/alanyl tRNA synthetase SAD; KEGG: aba:Acid345_4736 threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (583 aa) |
| | rpsB | PFAM: ribosomal protein S2; KEGG: bha:BH2427 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (324 aa) |
| | tsf | Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (278 aa) |
| | Emin_0653 | Subtilisin-like serine protease; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: bay:RBAM_035660 Epr; Belongs to the peptidase S8 family. (360 aa) |
| | rpmF | TIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein; KEGG: rxy:Rxyl_1376 ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (68 aa) |
| | infB | Translation initiation factor; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (826 aa) |
| | proS | Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (573 aa) |
| | Emin_0689 | Putative membrane-associated zinc metalloprotease; PFAM: peptidase M50; SMART: PDZ/DHR/GLGF domain protein; KEGG: dsy:DSY2538 hypothetical protein. (376 aa) |
| | Emin_0697 | TIGRFAM: phage portal protein, HK97 family; PFAM: portal protein; KEGG: pla:Plav_0903 phage portal protein, HK97 family. (399 aa) |
| | Emin_0702 | KEGG: chu:CHU_1364 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4); TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13 D-Ala-D-Ala carboxypeptidase C. (496 aa) |
| | frr | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (187 aa) |
| | Emin_0731 | Xaa-Pro aminopeptidase; PFAM: peptidase M24; KEGG: chy:CHY_1873 aminopeptidase P. (352 aa) |
| | Emin_0732 | Xaa-Pro aminopeptidase; PFAM: peptidase M24; KEGG: bld:BLi02617 YqhT. (351 aa) |
| | efp | Translation elongation factor; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (186 aa) |
| | rplS | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (141 aa) |
| | rpsP | PFAM: ribosomal protein S16; KEGG: sus:Acid_2572 ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (82 aa) |
| | fmt | Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (333 aa) |
| | clpP | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (195 aa) |
| | Emin_0784 | PFAM: Abortive infection protein; KEGG: cbf:CLI_1153 CAAX amino terminal protease family protein. (245 aa) |
| | asnS | TIGRFAM: asparaginyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; KEGG: ade:Adeh_2728 asparaginyl-tRNA synthetase. (431 aa) |
| | Emin_0819 | PFAM: LemA family protein; KEGG: tme:Tmel_0720 LemA family protein. (176 aa) |
| | Emin_0832 | Putative intracellular protease/amidase; TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: bld:BLi00848 hypothetical protein. (180 aa) |
| | Emin_0835 | D-Alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. (263 aa) |
| | Emin_0836 | Membrane carboxypeptidase; TIGRFAM: penicillin-binding protein 1C; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; Penicillin-binding domain protein; KEGG: ana:alr5101 penicillin-binding protein 2. (719 aa) |
| | tyrS | Tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (387 aa) |
| | Emin_0852 | Putative ADP acetyl-CoA synthetase; PFAM: CoA-binding domain protein; KEGG: dvl:Dvul_2560 CoA-binding domain protein. (732 aa) |
| | Emin_0876 | Hydrolases family protein; KEGG: ppg:PputGB1_2980 dienelactone hydrolase. (347 aa) |
| | argS | KEGG: bsu:BSU37330 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. (532 aa) |
| | def | N-Formylmethionyl-tRNA deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (176 aa) |
| | Emin_0918 | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: ctc:CTC00423 peptidase T. (383 aa) |
| | Emin_0927 | PFAM: Stage II sporulation E family protein; Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: dar:Daro_3360 protein phosphatase 2C-like. (273 aa) |
| | Emin_0928 | PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: cbe:Cbei_1929 protein kinase. (761 aa) |
| | rpmE | Ribosomal protein L31; Binds the 23S rRNA. (115 aa) |
| | Emin_0954 | PFAM: peptidase S14 ClpP; KEGG: mjl:Mjls_3582 ATP-dependent Clp protease proteolytic subunit; Belongs to the peptidase S14 family. (355 aa) |
| | Emin_0968 | KEGG: shn:Shewana3_4372 hypothetical protein; Belongs to the methyltransferase superfamily. (540 aa) |
| | Emin_0987 | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; peptidase S24 and S26 domain protein; KEGG: sma:SAV2463 LexA repressor. (261 aa) |
| | Emin_1020 | Transcriptional repressor, LexA family; TIGRFAM: LexA repressor; PFAM: LexA DNA-binding domain protein; peptidase S24 and S26 domain protein; Helix-turn-helix type 11 domain protein; KEGG: lic:LIC12654 transcriptional repressor (LexA family); Belongs to the peptidase S24 family. (201 aa) |
| | Emin_1086 | TIGRFAM: phage major capsid protein, HK97 family; PFAM: major capsid protein HK97; KEGG: spa:M6_Spy1138 phage prohead protease. (400 aa) |
| | prmC | Protein-(glutamine-N5) methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. (277 aa) |
| | Emin_1098 | TIGRFAM: peptide chain release factor 1; PFAM: Class I peptide chain release factor; PCRF domain protein; KEGG: csc:Csac_1523 peptide chain release factor 1. (358 aa) |
| | Emin_1100 | PFAM: 4'-phosphopantetheinyl transferase; KEGG: aba:Acid345_0467 4'-phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. (206 aa) |
| | hflX | GTP-binding conserved hypothetical protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (415 aa) |
| | Emin_1127 | TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein; KEGG: mth:MTH737 coenzyme F420-reducing hydrogenase, delta subunit homolog. (158 aa) |
| | lspA | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (165 aa) |
| | ileS | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (942 aa) |
| | Emin_1155 | Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. (145 aa) |
| | cysS | KEGG: vha:VIBHAR_02459 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. (460 aa) |
| | rpsO | Ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (89 aa) |
| | Emin_1192 | PFAM: peptidase M29 aminopeptidase II; KEGG: dol:Dole_2013 peptidase M29 aminopeptidase II. (399 aa) |
| | Emin_1198 | PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: hch:HCH_03714 signal transduction histidine kinase. (375 aa) |
| | Emin_1199 | Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: gur:Gura_3392 integral membrane sensor signal transduction histidine kinase. (604 aa) |
| | Emin_1217 | Periplasmic protease; KEGG: aae:aq_797 carboxyl-terminal protease; TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41; Belongs to the peptidase S41A family. (444 aa) |
| | Emin_1224 | KEGG: cth:Cthe_0686 tryptophanyl-tRNA synthetase; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib. (373 aa) |
| | Emin_1225 | Zn-dependent protease; PFAM: peptidase M50; KEGG: rma:Rmag_0347 peptidase M50. (226 aa) |
| | rpmH | PFAM: ribosomal protein L34; KEGG: maa:MAG678 50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. (45 aa) |
| | Emin_1268 | PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: nve:NEMVE_v1g178888 predicted protein Pfam: Peptidase_M3 Nse4 PROSITE: ZINC_PROTEASE. (681 aa) |
| | hypA | Hydrogenase expression/synthesis HypA family; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (134 aa) |
| | gatB | Glutamyl-tRNA(Gln) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (472 aa) |
| | pth | Aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (187 aa) |
| | rplY | Ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (219 aa) |
| | Emin_1309 | PFAM: protein kinase; Tetratricopeptide TPR_2 repeat protein; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: tte:TTE1500 serine/threonine protein kinase. (517 aa) |
| | Emin_1313 | Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; PFAM: peptidase S15; KEGG: swo:Swol_1667 hypothetical protein. (294 aa) |
| | acpS | Holo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (120 aa) |
| | ftsH | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins. (631 aa) |
| | Emin_1337 | Putative two-component system; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: aoe:Clos_1203 integral membrane sensor signal transduction histidine kinase. (562 aa) |
| | Emin_1346 | PFAM: biotin/lipoate A/B protein ligase; KEGG: cch:Cag_0906 lipoate-protein ligase A, putative. (238 aa) |
| | rplI | Ribosomal protein L9; Binds to the 23S rRNA. (152 aa) |
| | rpsR | Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (113 aa) |
| | rpsF | Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (104 aa) |
| | Emin_1362 | PFAM: DNA repair protein RadC; KEGG: rle:RL2068 DNA repair protein RadC; Belongs to the UPF0758 family. (228 aa) |
| | rplQ | PFAM: ribosomal protein L17; KEGG: bja:bll5375 50S ribosomal protein L17. (114 aa) |
| | rpsD | RNA-binding S4 domain protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (201 aa) |
| | rpsK | Ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (142 aa) |
| | rpsM | Ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (124 aa) |
| | rpmJ | PFAM: ribosomal protein L36; KEGG: abu:Abu_1016 50S ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. (37 aa) |
| | infA | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (70 aa) |
| | map | Methionine aminopeptidase, type; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (249 aa) |
| | rplO | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (151 aa) |
| | rpsE | Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (192 aa) |
| | rplR | Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (121 aa) |
| | Emin_1403 | Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. (184 aa) |
| | rpsH | Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rpsZ | Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa) |
| | rplE | Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (192 aa) |
| | rplX | Ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (101 aa) |
| | rplN | Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa) |
| | rpsQ | Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (89 aa) |
| | rpmC | PFAM: ribosomal protein L29; KEGG: mag:amb3122 ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (67 aa) |
| | rplP | Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (136 aa) |
| | rpsC | Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (239 aa) |
| | rplV | Ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). (118 aa) |
| | rpsS | Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (94 aa) |
| | rplB | Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (279 aa) |
| | rplW | Ribosomal protein L25/L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (98 aa) |
| | rplD | Ribosomal protein L4/L1e; Forms part of the polypeptide exit tunnel. (211 aa) |
| | rplC | Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (259 aa) |
| | rpsJ | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (117 aa) |
| | tuf | Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (395 aa) |
| | fusA | Translation elongation factor; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 sub [...] (700 aa) |
| | rpsG | Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (159 aa) |
| | rpsL | Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. (126 aa) |
| | rplL | Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (126 aa) |
| | rplJ | Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (173 aa) |
| | Emin_1434 | Threonyl- and alanyl-tRNA synthetase second additional domain; PFAM: Threonyl/alanyl tRNA synthetase SAD; KEGG: pdi:BDI_0673 alanyl-tRNA synthetase. (151 aa) |
| | metG | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (500 aa) |
| | Emin_1464 | PFAM: deoxyhypusine synthase; KEGG: cte:CT0011 deoxyhypusine synthase; Belongs to the deoxyhypusine synthase family. (375 aa) |
| | rplA | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (226 aa) |
| | rplK | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (144 aa) |
| | rpmG | PFAM: ribosomal protein L33; KEGG: tme:Tmel_0639 ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (54 aa) |
| | Emin_1498 | TIGRFAM: translation elongation factor Tu; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain protein; elongation factor Tu domain 2 protein; KEGG: scl:sce0841 elongation factor (EF). (395 aa) |
| | serS | Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (424 aa) |
| | Emin_1536 | PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: rno:64517 thimet oligopeptidase 1. (676 aa) |
| | rpsI | PFAM: ribosomal protein S9; KEGG: lhe:lhv_0344 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (131 aa) |
| | rplM | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (144 aa) |
