node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Emin_0056 | Emin_0633 | Emin_0056 | Emin_0633 | Uncharacterized conserved protein; PFAM: protein of unknown function DUF129; KEGG: bba:Bd1262 hypothetical protein. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.909 |
Emin_0056 | Emin_1092 | Emin_0056 | Emin_1092 | Uncharacterized conserved protein; PFAM: protein of unknown function DUF129; KEGG: bba:Bd1262 hypothetical protein. | Putative folylpoly-gamma-glutamate synthetase; TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: dol:Dole_0467 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | 0.901 |
Emin_0633 | Emin_0056 | Emin_0633 | Emin_0056 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Uncharacterized conserved protein; PFAM: protein of unknown function DUF129; KEGG: bba:Bd1262 hypothetical protein. | 0.909 |
Emin_0633 | Emin_0762 | Emin_0633 | Emin_0762 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | KEGG: ddi:DDB_0230139 dihydro-6-hydroxymethylpterin pyrophosphokinase (HppK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. | 0.999 |
Emin_0633 | Emin_1092 | Emin_0633 | Emin_1092 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Putative folylpoly-gamma-glutamate synthetase; TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: dol:Dole_0467 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | 0.996 |
Emin_0633 | folE | Emin_0633 | Emin_0634 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | PFAM: GTP cyclohydrolase I; KEGG: wsu:WS1225 GTP cyclohydrolase I. | 0.959 |
Emin_0636 | Emin_0761 | Emin_0636 | Emin_0761 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: tle:Tlet_1639 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | Putative 6-pyruvoyl-tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: tma:TM0038 6-pyruvoyl tetrahydrobiopterin synthase, putative. | 0.962 |
Emin_0636 | Emin_1220 | Emin_0636 | Emin_1220 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: tle:Tlet_1639 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | Putative dihydroneopterin monophosphate dephosphorylase; PFAM: Alkaline phosphatase; KEGG: pin:Ping_2627 alkaline phosphatase; Belongs to the alkaline phosphatase family. | 0.900 |
Emin_0636 | folE | Emin_0636 | Emin_0634 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: tle:Tlet_1639 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | PFAM: GTP cyclohydrolase I; KEGG: wsu:WS1225 GTP cyclohydrolase I. | 0.978 |
Emin_0636 | queC | Emin_0636 | Emin_1170 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: tle:Tlet_1639 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.871 |
Emin_0636 | queE | Emin_0636 | Emin_0635 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: tle:Tlet_1639 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | Putative 6- pyruvoyltetrahydropterin 2-reductase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.997 |
Emin_0636 | queF | Emin_0636 | Emin_1140 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: tle:Tlet_1639 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | GTP cyclohydrolase family protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.561 |
Emin_0761 | Emin_0636 | Emin_0761 | Emin_0636 | Putative 6-pyruvoyl-tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: tma:TM0038 6-pyruvoyl tetrahydrobiopterin synthase, putative. | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: tle:Tlet_1639 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | 0.962 |
Emin_0761 | Emin_0762 | Emin_0761 | Emin_0762 | Putative 6-pyruvoyl-tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: tma:TM0038 6-pyruvoyl tetrahydrobiopterin synthase, putative. | KEGG: ddi:DDB_0230139 dihydro-6-hydroxymethylpterin pyrophosphokinase (HppK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. | 0.854 |
Emin_0761 | Emin_1220 | Emin_0761 | Emin_1220 | Putative 6-pyruvoyl-tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: tma:TM0038 6-pyruvoyl tetrahydrobiopterin synthase, putative. | Putative dihydroneopterin monophosphate dephosphorylase; PFAM: Alkaline phosphatase; KEGG: pin:Ping_2627 alkaline phosphatase; Belongs to the alkaline phosphatase family. | 0.900 |
Emin_0761 | folE | Emin_0761 | Emin_0634 | Putative 6-pyruvoyl-tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: tma:TM0038 6-pyruvoyl tetrahydrobiopterin synthase, putative. | PFAM: GTP cyclohydrolase I; KEGG: wsu:WS1225 GTP cyclohydrolase I. | 0.937 |
Emin_0761 | queC | Emin_0761 | Emin_1170 | Putative 6-pyruvoyl-tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: tma:TM0038 6-pyruvoyl tetrahydrobiopterin synthase, putative. | ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.716 |
Emin_0761 | queE | Emin_0761 | Emin_0635 | Putative 6-pyruvoyl-tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: tma:TM0038 6-pyruvoyl tetrahydrobiopterin synthase, putative. | Putative 6- pyruvoyltetrahydropterin 2-reductase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.966 |
Emin_0761 | queF | Emin_0761 | Emin_1140 | Putative 6-pyruvoyl-tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: tma:TM0038 6-pyruvoyl tetrahydrobiopterin synthase, putative. | GTP cyclohydrolase family protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.561 |
Emin_0762 | Emin_0633 | Emin_0762 | Emin_0633 | KEGG: ddi:DDB_0230139 dihydro-6-hydroxymethylpterin pyrophosphokinase (HppK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |