STRINGSTRING
Emin_0024 Emin_0024 dapA dapA Emin_0034 Emin_0034 Emin_0035 Emin_0035 Emin_0036 Emin_0036 Emin_0049 Emin_0049 tpiA tpiA Emin_0160 Emin_0160 Emin_0167 Emin_0167 Emin_0234 Emin_0234 folD folD Emin_0284 Emin_0284 gpmA gpmA Emin_0297 Emin_0297 Emin_0298 Emin_0298 Emin_0344 Emin_0344 Emin_0353 Emin_0353 Emin_0355 Emin_0355 eno eno Emin_0404 Emin_0404 pfkA pfkA Emin_0415 Emin_0415 Emin_0423 Emin_0423 Emin_0438 Emin_0438 Emin_0527 Emin_0527 Emin_0558 Emin_0558 pgk pgk Emin_0618 Emin_0618 Emin_0675 Emin_0675 lysA lysA mgsA mgsA Emin_0711 Emin_0711 ackA ackA Emin_0743 Emin_0743 pckA pckA Emin_0755 Emin_0755 Emin_0770 Emin_0770 Emin_0772 Emin_0772 Emin_0806 Emin_0806 thrB thrB Emin_0859 Emin_0859 Emin_0860 Emin_0860 Emin_0875 Emin_0875 pfp pfp dapF dapF fhs fhs Emin_1116 Emin_1116 Emin_1117 Emin_1117 Emin_1182 Emin_1182 Emin_1183 Emin_1183 Emin_1229 Emin_1229 Emin_1269 Emin_1269 prs prs gpmI gpmI Emin_1363 Emin_1363 glyA glyA Emin_1475 Emin_1475 Emin_1476 Emin_1476 Emin_1477 Emin_1477 Emin_1478 Emin_1478
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Emin_0024TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: csc:Csac_1736 cysteine synthase A. (307 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (289 aa)
Emin_0034PFAM: aspartate/glutamate/uridylate kinase; KEGG: btk:BT9727_1658 aspartate kinase. (243 aa)
Emin_0035PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; KEGG: tme:Tmel_1873 aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (292 aa)
Emin_0036PFAM: dihydrodipicolinate reductase; KEGG: bba:Bd0047 hypothetical protein; Belongs to the DapB family. (218 aa)
Emin_0049FAD/FMN-containing dehydrogenase; PFAM: FAD linked oxidase domain protein; KEGG: rca:Rcas_3429 D-lactate dehydrogenase (cytochrome). (656 aa)
tpiAGlycolysis; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (252 aa)
Emin_0160PFAM: ROK family protein; KEGG: aba:Acid345_3865 sugar kinase. (322 aa)
Emin_0167TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: chy:CHY_1991 putative oxidoreductase. (465 aa)
Emin_0234TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: tko:TK1781 succinyl-diaminopimelate desuccinylase. (411 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (288 aa)
Emin_0284PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: psa:PST_1198 homoserine dehydrogenase. (441 aa)
gpmAPhosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa)
Emin_0297KEGG: chy:CHY_1375 fumarate hydratase; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region. (279 aa)
Emin_0298Putative fumarate hydratase; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: mta:Moth_2282 hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region. (171 aa)
Emin_0344KEGG: dps:DP1368 pyruvate phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing protein; pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; Belongs to the PEP-utilizing enzyme family. (929 aa)
Emin_0353Fructose-1,6-bisphosphate aldolase, class II; KEGG: pca:Pcar_2253 fructose-bisphosphate aldolase; TIGRFAM: ketose-bisphosphate aldolase; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II. (325 aa)
Emin_0355PFAM: Transketolase central region; KEGG: mxa:MXAN_7358 transketolase; Belongs to the transketolase family. (776 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (423 aa)
Emin_0404PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: cac:CAC0972 isocitrate dehydrogenase. (334 aa)
pfkA6-Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (368 aa)
Emin_0415Acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (172 aa)
Emin_0423PFAM: glycerate kinase; KEGG: tex:Teth514_1896 glycerate kinase; Belongs to the glycerate kinase type-1 family. (369 aa)
Emin_0438KEGG: pdi:BDI_3092 serine acetyltransferase. (284 aa)
Emin_0527Glutamate dehydrogenase (NADP+); PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: mvn:Mevan_1556 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (450 aa)
Emin_0558KEGG: rru:Rru_A2465 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. (473 aa)
pgkPFAM: phosphoglycerate kinase; KEGG: cno:NT01CX_1411 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (399 aa)
Emin_0618Glyceraldehyde-3-phosphate dehydrogenase, type; KEGG: bvu:BVU_3585 glyceraldehyde 3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (338 aa)
Emin_0675PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: drm:Dred_1955 phosphoesterase, RecJ domain protein. (331 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (417 aa)
mgsAMethylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (151 aa)
Emin_0711Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (383 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (452 aa)
Emin_0743PFAM: ribulose-phosphate 3-epimerase; KEGG: bba:Bd2756 probable ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (226 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (534 aa)
Emin_0755PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase_; KEGG: cth:Cthe_0423 iron-containing alcohol dehydrogenase. (872 aa)
Emin_0770TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: deh:cbdb_A1050 glutamine synthetase, type I. (450 aa)
Emin_0772PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase_; KEGG: mar:MAE_49340 aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (887 aa)
Emin_0806Pyruvate:ferredoxin oxidoreductase; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: gur:Gura_4330 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (1185 aa)
thrBKEGG: pla:Plav_0685 homoserine kinase; TIGRFAM: homoserine kinase; PFAM: aminoglycoside phosphotransferase; Belongs to the pseudomonas-type ThrB family. (317 aa)
Emin_0859KEGG: pfo:Pfl_1028 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. (460 aa)
Emin_0860PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: aae:aq_1812 homoserine dehydrogenase. (438 aa)
Emin_0875Decarboxylase family protein; PFAM: Carboxymuconolactone decarboxylase; KEGG: gur:Gura_4370 cupin 2, conserved barrel domain protein. (168 aa)
pfp6-Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (562 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (274 aa)
fhsPutative formyltetrahydrofolate synthetase; PFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: cth:Cthe_2399 formate--tetrahydrofolate ligase. (556 aa)
Emin_1116PFAM: phosphoglucose isomerase (PGI); KEGG: aba:Acid345_2810 transaldolase; Belongs to the GPI family. (552 aa)
Emin_1117TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase; KEGG: hau:Haur_0488 sugar-phosphate isomerase, RpiB/LacA/LacB family. (150 aa)
Emin_1182PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: chy:CHY_1999 pyruvate carboxylase subunit B. (124 aa)
Emin_1183Acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (455 aa)
Emin_1229Plp-dependent enzyme; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: mta:Moth_1998 threonine synthase. (416 aa)
Emin_1269PFAM: phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: sun:SUN_1277 phosphoglucomutase, alpha-D-glucose phosphate-specific. (518 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (316 aa)
gpmIPhosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (518 aa)
Emin_1363TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: amt:Amet_2023 dihydrolipoamide dehydrogenase. (448 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
Emin_1475Putative 2-ketovalerate ferredoxin oxidoreductase subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ0146 2-ketoglutarate ferredoxin oxidoreductase, subunit delta (KorD). (67 aa)
Emin_1476PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: csc:Csac_1549 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (375 aa)
Emin_14772-Ketovalerate ferredoxin oxidoreductase subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: swo:Swol_1399 putative keto/oxoacid ferredoxin oxidoreductase, beta subunit. (247 aa)
Emin_1478TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: tle:Tlet_1758 pyruvate/ketoisovalerate oxidoreductase, gamma subunit. (178 aa)
Your Current Organism:
Elusimicrobium minutum
NCBI taxonomy Id: 445932
Other names: E. minutum Pei191, Elusimicrobium minutum Pei191, Elusimicrobium minutum str. Pei191, Elusimicrobium minutum strain Pei191
Server load: low (18%) [HD]