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| | Ndas_0003 | 6-phosphogluconate dehydrogenase, decarboxylating; COGs: COG1023 6-phosphogluconate dehydrogenase; InterProIPR004849:IPR016040:IPR002204:IPR006115:IPR 013328:IPR008927:IPR006114:IPR006184:IPR006183; KEGG: tfu:Tfu_0003 6-phosphogluconate dehydrogenase-like protein; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain protein; SPTR: C1YR91 6-phosphogluconate dehydrogenase, decarboxylating; TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase, C-term [...] (299 aa) |
| | Ndas_0017 | COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR011766:IPR012001:IPR012000; KEGG: sen:SACE_5551 thiamine pyrophosphate protein; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; SPTR: C1YR80 Thiamine pyrophosphate-dependent enzyme, possible carboligase or decarboxylase; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; Bel [...] (599 aa) |
| | Ndas_0025 | COGs: COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit; InterPro IPR017596:IPR001017; KEGG: art:Arth_3193 pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase E1 component; PRIAM: Pyruvate dehydrogenase (acetyl-transferring); SPTR: C1YR72 Pyruvate dehydrogenase E1 component, alpha subunit; TIGRFAM: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; PFAM: Dehydrogenase E1 component; TIGRFAM: pyruvate dehydrogenase E1 component, alpha subunit. (361 aa) |
| | Ndas_0026 | Transketolase central region; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR009014:IPR005476:IPR005475:IPR015941; KEGG: art:Arth_3192 transketolase, central region; PFAM: Transketolase central region; Transketolase domain protein; SMART: Transketolase central region; SPTR: C1YR71 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (330 aa) |
| | Ndas_0027 | COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterProIPR011053:IPR004167:IPR003016:IPR000089:IPR 001078; KEGG: aau:AAur_3154 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; PRIAM: Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; SPTR: C1YR70 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; PFAM: 2-oxoacid dehydroge [...] (466 aa) |
| | Ndas_0059 | Cobalamin B12-binding domain protein; COGs: COG2185 Methylmalonyl-CoA mutase C-terminal domain/subunit (cobalamin-binding); InterPro IPR006158:IPR006159; KEGG: stp:Strop_3814 cobalamin B12-binding domain-containing protein; PFAM: cobalamin B12-binding domain protein; SPTR: C1YI05 Methylmalonyl-CoA mutase family protein; PFAM: B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain. (136 aa) |
| | sucC | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (393 aa) |
| | sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (292 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | fumC | Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (462 aa) |
| | Ndas_0114 | Fructose-1,6-bisphosphatase, class II; COGs: COG1494 Fructose-1 6-bisphosphatase/sedoheptulose 1 7-bisphosphatase and related protein; InterPro IPR004464; KEGG: tfu:Tfu_0464 fructose 1,6-bisphosphatase II; PFAM: GlpX family protein; PRIAM: Fructose-bisphosphatase; SPTR: C1YHM0 Fructose-1,6-bisphosphatase, class II; TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: Bacterial fructose-1,6-bisphosphatase, glpX-encoded; TIGRFAM: fructose-1,6-bisphosphatase, class II. (346 aa) |
| | Ndas_0214 | COGs: COG1254 Acylphosphatase; InterPro IPR001792:IPR017968; KEGG: tfu:Tfu_0653 acylphosphatase; PFAM: acylphosphatase; SPTR: C1YHR5 Acylphosphatase; PFAM: Acylphosphatase. (95 aa) |
| | Ndas_0263 | COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016161:IPR015590:IPR016160:IPR016162; KEGG: art:Arth_1894 betaine-aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: C1YHE4 4-hydroxybenzaldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family. (494 aa) |
| | Ndas_0356 | methylmalonyl-CoA epimerase; COGs: COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins; InterPro IPR004360:IPR017515; KEGG: tfu:Tfu_2395 methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: C1YH54 Methylmalonyl-CoA epimerase; TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase. (192 aa) |
| | Ndas_0358 | LAO/AO transport system ATPase; COGs: COG1703 Putative periplasmic protein kinase ArgK and related GTPase of G3E family; InterPro IPR005129:IPR003593; KEGG: sro:Sros_1698 LAO/AO transport system ATPase; PFAM: ArgK protein; SMART: AAA ATPase; SPTR: C1YH52 LAO/AO transport system ATPase; TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; TIGRFAM: LAO/AO transport system ATPase. (318 aa) |
| | Ndas_0363 | COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR014348:IPR006099:IPR006098:IPR016176; KEGG: sco:SCO5415 isobutyryl-CoA mutase A; PFAM: methylmalonyl-CoA mutase; PRIAM: Methylmalonyl-CoA mutase; SPTR: C1YH46 Methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: Methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain. (575 aa) |
| | Ndas_0366 | Malate dehydrogenase (oxaloacetate-decarboxylating); COGs: COG0281 Malic enzyme; InterPro IPR016040:IPR001891:IPR012301:IPR012302; KEGG: tfu:Tfu_2390 malate dehydrogenase (oxaloacetate decarboxylating); PFAM: malic protein NAD-binding; malic protein domain protein; PRIAM: Malate dehydrogenase (oxaloacetate-decarboxylating); SPTR: C1YH42 Malic enzyme; PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain. (468 aa) |
| | Ndas_0429 | COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: ami:Amir_2275 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: C1YLX2 Acyl-CoA synthetase/AMP-acid ligase; PFAM: AMP-binding enzyme. (572 aa) |
| | Ndas_0447 | Haloacid dehalogenase, type II; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005833:IPR006328:IPR006388:IPR005834; KEGG: sma:SAV_737 2-haloalkanoic acid dehalogenase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: C1YLV4 2-haloalkanoic acid dehalogenase, type II; TIGRFAM: haloacid dehalogenase, type II; HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like); TIGRFAM: Haloacid dehalogenase superfamily, subfamily IA, variant 2 with 3rd motif like haloacid dehalogenase; 2-haloalkanoic acid dehalogenase, type II. (230 aa) |
| | Ndas_0501 | Domain of unknown function DUF2394; COGs: COG2706 3-carboxymuconate cyclase; InterPro IPR019758:IPR015943:IPR019405; KEGG: tfu:Tfu_2315 putative secreted protein; PFAM: Domain of unknown function DUF2394; SPTR: C1YLP9 3-carboxymuconate cyclase; PFAM: 3-carboxy-cis,cis-muconate lactonizing enzyme. (365 aa) |
| | Ndas_0660 | ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: sro:Sros_2180 transcriptional regulator ROK family; PFAM: ROK family protein; SPTR: C1YNK1 Transcriptional regulator/sugar kinase; PFAM: ROK family. (404 aa) |
| | Ndas_0745 | Pyruvate, phosphate dikinase; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterProIPR018274:IPR002192:IPR008279:IPR000121:IPR 010121:IPR013815:IPR013816:IPR015813; KEGG: tfu:Tfu_0863 pyruvate phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; SPTR: C1YNB1 Pyruvate phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain; TIGRFAM: pyru [...] (898 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa) |
| | Ndas_0829 | COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000639:IPR000073; KEGG: cag:Cagg_2835 alpha/beta hydrolase fold protein; PFAM: alpha/beta hydrolase fold; SPTR: C1YQS0 Predicted hydrolase or acyltransferase of alpha/beta superfamily; PFAM: alpha/beta hydrolase fold. (298 aa) |
| | Ndas_0858 | COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056:IPR013785:IPR011060; KEGG: sro:Sros_2830 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: C1YQN9 Ribulose-5-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase. (223 aa) |
| | Ndas_0943 | COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterProIPR014276:IPR000089:IPR004167:IPR001078:IPR 011053:IPR003016; KEGG: tfu:Tfu_0993 2-oxoglutarate dehydrogenase E2 component; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; SPTR: C1YQF3 2-oxoglutarate dehydrogenase E2 component; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: 2-oxoacid dehydrogenases acyltransferase (cataly [...] (600 aa) |
| | Ndas_0944 | COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027:IPR000815:IPR006258:IPR004099:IPR 016156:IPR012999; KEGG: tfu:Tfu_0994 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: C1YQF2 Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase. (458 aa) |
| | Ndas_0956 | COGs: COG1929 Glycerate kinase; InterPro IPR004381:IPR018193; KEGG: tfu:Tfu_1010 glycerate kinase; PFAM: glycerate kinase; PRIAM: Glycerate kinase; SPTR: C1YQD9 Glycerate kinase; TIGRFAM: glycerate kinase; PFAM: Glycerate kinase family; TIGRFAM: glycerate kinase; Belongs to the glycerate kinase type-1 family. (373 aa) |
| | Ndas_1021 | COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000639:IPR000073; KEGG: cai:Caci_6541 alpha/beta hydrolase fold protein; PFAM: alpha/beta hydrolase fold; SPTR: C1YTN7 Predicted hydrolase or acyltransferase of alpha/beta superfamily (Fragment); PFAM: alpha/beta hydrolase fold. (286 aa) |
| | Ndas_1152 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1126 aa) |
| | Ndas_1245 | COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020845:IPR000873; KEGG: rpe:RPE_4586 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: C1YU92 Acyl-CoA synthetase/AMP-acid ligase; PFAM: AMP-binding enzyme. (548 aa) |
| | Ndas_1255 | Alcohol dehydrogenase GroES domain protein; COGs: COG1064 Zn-dependent alcohol dehydrogenase; InterProIPR013149:IPR016040:IPR011032:IPR002328:IPR 013154; KEGG: ach:Achl_1768 alcohol dehydrogenase GroES domain protein; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; SPTR: C1YU81 Zn-dependent alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (349 aa) |
| | Ndas_1337 | COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016161:IPR015590:IPR016160:IPR016162; KEGG: dra:DR_A0126 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; PRIAM: Aldehyde dehydrogenase (NAD(+)); SPTR: C1YRM3 NAD-dependent aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. (486 aa) |
| | Ndas_1484 | ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: tfu:Tfu_1811 polyphosphate glucokinase; PFAM: ROK family protein; SPTR: C1YJA3 Transcriptional regulator/sugar kinase; PFAM: ROK family. (254 aa) |
| | Ndas_1689 | Alcohol dehydrogenase GroES domain protein; COGs: COG1064 Zn-dependent alcohol dehydrogenase; InterProIPR013149:IPR016040:IPR002328:IPR011032:IPR 013154; KEGG: jde:Jden_0114 alcohol dehydrogenase GroES domain protein; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; SPTR: C1YP45 Zn-dependent alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase. (349 aa) |
| | Ndas_1855 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027:IPR004099:IPR000815:IPR001327:IPR 016156; KEGG: rxy:Rxyl_1765 pyridine nucleotide-disulphide oxidoreductase dimerisation region; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: C1YWE5 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component; PFAM: Pyridine nucleotide-disulphide oxidoreductase; [...] (452 aa) |
| | Ndas_1930 | COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterProIPR016161:IPR012394:IPR015590:IPR016160:IPR 016162; KEGG: sma:SAV_1187 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: C1YTD4 NAD-dependent aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. (480 aa) |
| | Ndas_1935 | COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016161:IPR015590:IPR016162:IPR016160; KEGG: mva:Mvan_1643 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: C1YTC9 Delta-1-piperideine-6-carboxylate dehydrogenase; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. (515 aa) |
| | Ndas_2139 | COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073:IPR000639; KEGG: sco:SCO0899 hydrolase; PFAM: alpha/beta hydrolase fold; SPTR: C1YMN8 Predicted hydrolase or acyltransferase of alpha/beta superfamily; PFAM: alpha/beta hydrolase fold. (292 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (358 aa) |
| | Ndas_2196 | COGs: COG3957 Phosphoketolase; InterProIPR009014:IPR018969:IPR019790:IPR019789:IPR 005593:IPR018970; KEGG: tcu:Tcur_1271 phosphoketolase; PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase-like; PRIAM: Phosphoketolase; SPTR: C1YTZ6 Phosphoketolase; PFAM: XFP N-terminal domain; D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; XFP C-terminal domain. (782 aa) |
| | Ndas_2198 | COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: tfu:Tfu_1546 putative acyl-CoA synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: C1YTZ4 Acyl-CoA synthetase/AMP-acid ligase; PFAM: AMP-binding enzyme. (539 aa) |
| | Ndas_2358 | COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771:IPR013785; KEGG: kra:Krad_2157 ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: C1YMH3 Fructose-bisphosphate aldolase; TIGRFAM: ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases. (278 aa) |
| | Ndas_2360 | ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: sen:SACE_7183 transcriptional regulator; PFAM: ROK family protein; SPTR: C1YMH1 Transcriptional regulator/sugar kinase; PFAM: ROK family; TIGRFAM: ROK family protein (putative glucokinase). (302 aa) |
| | Ndas_2506 | Transketolase central region; COGs: COG3958 Transketolase C-terminal subunit; InterPro IPR009014:IPR005476:IPR005475:IPR015941; KEGG: ach:Achl_0406 transketolase central region; PFAM: Transketolase central region; Transketolase domain protein; SMART: Transketolase central region; SPTR: C1YM25 Transketolase subunit B; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (343 aa) |
| | Ndas_2507 | Transketolase domain protein; COGs: COG3959 Transketolase N-terminal subunit; InterPro IPR005474; KEGG: sen:SACE_4350 transketolase; PFAM: Transketolase domain protein; SPTR: C1YM24 Transketolase subunit A; PFAM: Transketolase, thiamine diphosphate binding domain. (291 aa) |
| | Ndas_2509 | COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR016040:IPR008927:IPR006115:IPR013328; KEGG: xau:Xaut_1538 3-hydroxyisobutyrate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; PRIAM: 3-hydroxyisobutyrate dehydrogenase; SPTR: C1YM22 Beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase. (298 aa) |
| | pgi | COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR018189:IPR001672; KEGG: sma:SAV_6302 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); PRIAM: Glucose-6-phosphate isomerase; SPTR: C1YT61 Glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase; Belongs to the GPI family. (569 aa) |
| | Ndas_2703 | Alcohol dehydrogenase GroES domain protein; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR016040:IPR011032:IPR013154; KEGG: tfu:Tfu_2814 putative dehydrogenase; PFAM: Alcohol dehydrogenase GroES domain protein; SPTR: C1YKE8 Theronine dehydrogenase-like Zn-dependent dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain. (348 aa) |
| | Ndas_2974 | Transketolase; COGs: COG0021 Transketolase; InterProIPR015941:IPR005474:IPR005475:IPR005476:IPR 009014:IPR005478; KEGG: tfu:Tfu_2002 transketolase; PFAM: Transketolase domain protein; Transketolase central region; SPTR: C1YRW9 Transketolase; TIGRFAM: transketolase; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yeast; Belongs to the transketolase family. (697 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (368 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (517 aa) |
| | Ndas_2977 | COGs: COG3429 Glucose-6-P dehydrogenase subunit; InterPro IPR019297; KEGG: tfu:Tfu_2006 hypothetical protein; PFAM: Glucose-6-phosphate dehydrogenase subunit; SPTR: C1YRW5 Glucose-6-P dehydrogenase subunit; PFAM: Glucose-6-phosphate dehydrogenase subunit; TIGRFAM: opcA protein. (308 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (248 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (258 aa) |
| | pgk | COGs: COG0126 3-phosphoglycerate kinase; InterPro IPR001576:IPR015901:IPR015911:IPR015824; KEGG: tfu:Tfu_2016 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: C1YRT2 Phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (394 aa) |
| | Ndas_3010 | COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR020831:IPR020832:IPR020828:IPR020829:IPR 016040:IPR006424; KEGG: tfu:Tfu_2017 glyceraldehyde-3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: C1YRT1 Glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-termina [...] (334 aa) |
| | pfp | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (341 aa) |
| | Ndas_3129 | Glucokinase, ROK family; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600:IPR004654; KEGG: tfu:Tfu_1033 glucokinase; PFAM: ROK family protein; SPTR: C1YW51 Glucokinase; TIGRFAM: glucokinase, ROK family; PFAM: ROK family; TIGRFAM: ROK family protein (putative glucokinase). (315 aa) |
| | Ndas_3162 | COGs: COG0469 Pyruvate kinase; InterProIPR015793:IPR015794:IPR015813:IPR018209:IPR 015795:IPR011037:IPR001697; KEGG: tfu:Tfu_1179 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: Q47QQ2 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. (477 aa) |
| | Ndas_3221 | COGs: COG1960 Acyl-CoA dehydrogenase; InterProIPR013786:IPR002655:IPR006091:IPR009100:IPR 006090:IPR013764:IPR006092:IPR009075:IPR012258; KEGG: tfu:Tfu_2239 hypothetical protein; PFAM: acyl-CoA dehydrogenase domain protein; acyl-CoA oxidase domain protein; SPTR: C1YSS8 Acyl-CoA dehydrogenase; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA oxidase; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain. (656 aa) |
| | Ndas_3241 | Biotin/lipoyl attachment domain-containing protein; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089:IPR003016:IPR011053; KEGG: art:Arth_2566 biotin/lipoyl attachment domain-containing protein; PFAM: biotin/lipoyl attachment domain-containing protein; SPTR: C1YSQ8 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; PFAM: Biotin-requiring enzyme. (114 aa) |
| | Ndas_3242 | Transketolase central region; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR005475:IPR005476:IPR015941:IPR009014; KEGG: aau:AAur_2539 pyruvate dehydrogenase E1 component, beta subunit; PFAM: Transketolase central region; Transketolase domain protein; SPTR: C1YSQ7 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (339 aa) |
| | Ndas_3243 | 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); COGs: COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit; InterPro IPR001017; KEGG: art:Arth_2564 pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase E1 component; PRIAM: 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); SPTR: C1YSQ6 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component alpha subunit; PFAM: Dehydrogenase E1 component. (375 aa) |
| | Ndas_3247 | COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR016162:IPR016161; KEGG: sgr:SGR_2631 putative aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: C1YSQ2 NAD-dependent aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family. (320 aa) |
| | Ndas_3248 | COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR016162:IPR016161; KEGG: stp:Strop_0827 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; PRIAM: Betaine-aldehyde dehydrogenase; SPTR: C1YSQ1 Aldehyde dehydrogenase (Acceptor); PFAM: Aldehyde dehydrogenase family. (476 aa) |
| | Ndas_3249 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. (315 aa) |
| | Ndas_3352 | COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterProIPR000262:IPR013785:IPR008259:IPR017934:IPR 012133; KEGG: rer:RER_02640 FMN-dependent dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; PRIAM: Lactate 2-monooxygenase; SPTR: C1YT09 Alpha-hydroxyacid dehydrogenase, FMN-dependent L-lactate dehydrogenase; PFAM: FMN-dependent dehydrogenase. (387 aa) |
| | Ndas_3408 | COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500:IPR011860; KEGG: tfu:Tfu_2202 ribose-5-phosphate isomerase B; PFAM: Ribose/galactose isomerase; SPTR: C1YQC7 Ribose 5-phosphate isomerase; TIGRFAM: ribose 5-phosphate isomerase; sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase; sugar-phosphate isomerases, RpiB/LacA/LacB family. (155 aa) |
| | Ndas_3410 | COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016161:IPR015590:IPR016162:IPR016160; KEGG: sro:Sros_7323 betaine-aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: C1YQC5 NAD-dependent aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. (473 aa) |
| | Ndas_3416 | Amidase; COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; InterPro IPR020556:IPR000120; KEGG: tfu:Tfu_2207 amidase; PFAM: Amidase; SPTR: C1YQB9 Amidase, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit; PFAM: Amidase; Belongs to the amidase family. (486 aa) |
| | Ndas_3628 | COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016161:IPR015590:IPR016162:IPR016160; KEGG: tfu:Tfu_0744 aldehyde dehydrogenase (NAD+); PFAM: Aldehyde Dehydrogenase; SPTR: C1YQV0 NAD-dependent aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. (474 aa) |
| | Ndas_3640 | Carbohydrate kinase, thermoresistant glucokinase family; COGs: COG3265 Gluconate kinase; InterPro IPR006001:IPR000623; KEGG: tfu:Tfu_2114 gluconate kinase; PFAM: shikimate kinase; PRIAM: Gluconokinase; SPTR: C1YQT8 Gluconate kinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: Shikimate kinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family. (176 aa) |
| | Ndas_3663 | COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR004632:IPR015424:IPR005814:IPR015421; KEGG: tfu:Tfu_0690 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; SPTR: C1YR31 4-aminobutyrate aminotransferase; TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (445 aa) |
| | Ndas_3669 | COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR015424:IPR005814:IPR015421; KEGG: tfu:Tfu_0686 aminotransferase; PFAM: aminotransferase class-III; SPTR: C1YU66 Aminotransferase; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa) |
| | Ndas_3670 | COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterProIPR016161:IPR010061:IPR015590:IPR016162:IPR 016160; KEGG: tfu:Tfu_0687 methylmalonate-semialdehyde dehydrogenase [acylating]; PFAM: Aldehyde Dehydrogenase; SPTR: C1YU65 Methylmalonic acid semialdehyde dehydrogenase; TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase. (502 aa) |
| | Ndas_3681 | COGs: COG0567 2-oxoglutarate dehydrogenase complex dehydrogenase (E1); InterPro IPR011603:IPR001078:IPR001017:IPR005475; KEGG: tfu:Tfu_0566 alpha-ketoglutarate decarboxylase; PFAM: Transketolase central region; dehydrogenase E1 component; catalytic domain of components of various dehydrogenase complexes; SPTR: C1YU54 2-oxoglutarate dehydrogenase E1 component; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Dehydrogenase E1 component; Transketolase, pyrimidine binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 [...] (1219 aa) |
| | Ndas_3685 | Malate dehydrogenase (oxaloacetate-decarboxylating); COGs: COG0281 Malic enzyme; InterPro IPR016040:IPR012301:IPR012302; KEGG: tfu:Tfu_0562 malate dehydrogenase (oxaloacetate decarboxylating); PFAM: malic protein NAD-binding; malic protein domain protein; PRIAM: Malate dehydrogenase (oxaloacetate-decarboxylating); SPTR: C1YU50 Malic enzyme; PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain. (395 aa) |
| | Ndas_3730 | Sugar-specific permease EIIA 1 domain protein; COGs: COG2190 Phosphotransferase system IIA components; InterPro IPR011055:IPR001127; KEGG: sen:SACE_2062 PTS system, glucose-specific component; PFAM: sugar-specific permease EIIA 1 domain; SPTR: C1YLC1 PTS system N-acetylglucosamine-specific EIIA component; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; TIGRFAM: PTS system, glucose subfamily, IIA component. (162 aa) |
| | Ndas_3731 | Phosphotransferase system EIIB/cysteine, phosphorylation site; COGs: COG1264 Phosphotransferase system IIB components; InterPro IPR001996:IPR018113; KEGG: rop:ROP_12540 phosphotransferase system enzyme IIB component; PFAM: Phosphotransferase system EIIB/cysteine, phosphorylation site; SPTR: C1YLC0 PTS system N-acetylglucosamine-specific EIIB component; PFAM: phosphotransferase system, EIIB; TIGRFAM: PTS system, glucose-like IIB component. (78 aa) |
| | Ndas_3734 | COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterPro IPR013013:IPR003352:IPR000326; KEGG: sro:Sros_1422 protein-N(pi)-phosphohistidine--sugarphosphotran sferase; PFAM: phosphotransferase system EIIC; phosphoesterase PA-phosphatase related; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: C1YLB7 PTS system IIC component; PFAM: Phosphotransferase system, EIIC. (492 aa) |
| | Ndas_3921 | COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterProIPR001041:IPR009051:IPR004489:IPR001450:IPR 012675:IPR012285:IPR006058:IPR017900:IPR017896; KEGG: tfu:Tfu_2451 succinate dehydrogenase/fumarate reductase iron-sulfur subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; ferredoxin; SPTR: C1YKT0 Succinate dehydrogenase subunit B; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. (248 aa) |
| | Ndas_3922 | COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR015939:IPR011280:IPR003953:IPR004112; KEGG: tfu:Tfu_2452 succinate dehydrogenase flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PRIAM: Succinate dehydrogenase; SPTR: C1YKS9 Succinate dehydrogenase subunit A; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit, Bacillus subtilis subgroup. (648 aa) |
| | Ndas_3923 | Succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; InterPro IPR011138; KEGG: tfu:Tfu_2453 succinate dehydrogenase subunit C; SPTR: C1YKS8 Succinate dehydrogenase subunit C; TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; PFAM: Succinate dehydrogenase/Fumarate reductase transmembrane subunit; TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family. (235 aa) |
| | Ndas_3925 | KEGG: nfa:nfa56010 hypothetical protein; SPTR: C1YKS6 Putative uncharacterized protein. (270 aa) |
| | Ndas_3926 | COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR015939:IPR004112:IPR003953; KEGG: tcu:Tcur_1116 fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: C1YKS5 Succinate dehydrogenase subunit A; PFAM: domain; FAD binding domain. (680 aa) |
| | Ndas_3927 | COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterProIPR001041:IPR006058:IPR012675:IPR012285:IPR 009051:IPR004489; KEGG: nfa:nfa56030 fumarate reductase iron-sulfur subunit; PFAM: ferredoxin; SPTR: C1YKS4 Succinate dehydrogenase subunit B; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. (263 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (908 aa) |
| | Ndas_3941 | COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022:IPR000438:IPR011762:IPR011763; KEGG: tfu:Tfu_2555 propionyl-CoA carboxylase complex B subunit; PFAM: carboxyl transferase; SPTR: C1YKQ9 Acetyl-CoA carboxylase, carboxyltransferase component (Subunits alpha and beta); PFAM: Carboxyl transferase domain. (536 aa) |
| | Ndas_3943 | Carbamoyl-phosphate synthase L chain ATP-binding protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR016185:IPR011054:IPR011053:IPR005481:IPR 005479:IPR005482:IPR000089:IPR013817:IPR013816:IPR001882:I PR011761:IPR011764; KEGG: tfu:Tfu_2557 putative acyl-CoA carboxylase, alpha subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: C1YKQ7 Acetyl/propionyl-CoA carboxylase, alpha subunit; PFAM: Carbam [...] (589 aa) |
| | Ndas_3950 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR016156:IPR013027:IPR004099:IPR000815; KEGG: tfu:Tfu_2559 flavoprotein disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: C1YKQ0 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreducta [...] (481 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (322 aa) |
| | Ndas_4002 | Transketolase central region; COGs: COG3958 Transketolase C-terminal subunit; InterPro IPR009014:IPR005476:IPR005475:IPR015941; KEGG: sen:SACE_5762 transketolase B subunit; PFAM: Transketolase central region; Transketolase domain protein; SMART: Transketolase central region; SPTR: C1YV47 Transketolase subunit B; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (299 aa) |
| | Ndas_4003 | Transketolase domain protein; COGs: COG3959 Transketolase N-terminal subunit; InterPro IPR005474; KEGG: sgr:SGR_921 putative transketolase; PFAM: Transketolase domain protein; SPTR: C1YV46 Transketolase, beta subunit; PFAM: Transketolase, thiamine diphosphate binding domain. (236 aa) |
| | sucD-2 | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (312 aa) |
| | sucC-2 | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (395 aa) |
| | pckG | Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (605 aa) |
| | rbsK | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (301 aa) |
| | Ndas_4226 | 1-phosphofructokinase; COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR011611:IPR017583; KEGG: tfu:Tfu_0696 putative 6-phosphofructokinase: 1-phosphofructokinase; PFAM: PfkB domain protein; PRIAM: 1-phosphofructokinase; SPTR: C1YGY6 1-phosphofructokinase; TIGRFAM: 1-phosphofructokinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: 1-phosphofructokinase. (313 aa) |
| | gpmA | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa) |
| | Ndas_4410 | COGs: COG0372 Citrate synthase; InterProIPR016141:IPR002020:IPR016142:IPR010953:IPR 019810; KEGG: rop:ROP_50580 citrate synthase; PFAM: Citrate synthase; SPTR: C1YGF6 Citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family. (429 aa) |
| | Ndas_4633 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (340 aa) |
| | zwf-2 | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (492 aa) |
| | Ndas_4757 | COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016162:IPR016161:IPR015590:IPR016160; KEGG: tfu:Tfu_2949 succinate semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; PRIAM: Succinate-semialdehyde dehydrogenase; SPTR: C1YPA1 Succinate semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (487 aa) |
| | Ndas_4758 | Acetylornithine transaminase; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR015424:IPR005814:IPR015421; KEGG: sen:SACE_3766 4-aminobutyrate transaminase; PFAM: aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: C1YPA0 Aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (418 aa) |
| | pdhA | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (408 aa) |
| | Ndas_4805 | Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (337 aa) |
| | Ndas_4806 | Catalytic domain of components of various dehydrogenase complexes; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR004167:IPR001078:IPR000089:IPR011053; KEGG: tfu:Tfu_3051 pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: C1YP51 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; PFAM: 2-oxo [...] (436 aa) |
| | Ndas_4869 | Haloacid dehalogenase domain protein hydrolase; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834; KEGG: afw:Anae109_1202 haloacid dehalogenase, type II; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: C1YJ31 Predicted HAD superfamily hydrolase, COG1011; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 2-haloalkanoic acid dehalogenase, type II. (236 aa) |
| | Ndas_5088 | Thiamine pyrophosphate protein domain protein TPP-binding protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: tfu:Tfu_2675 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: C1YI77 2-oxoacid:ferredoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. (363 aa) |
| | Ndas_5089 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002869:IPR009014:IPR002880; KEGG: tfu:Tfu_2674 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: C1YI76 2-oxoacid:ferredoxin oxidoreductase, alpha subunit; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase. (616 aa) |
| | Ndas_5161 | Glucokinase, ROK family; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR004654:IPR000600; KEGG: tfu:Tfu_0273 glucokinase; PFAM: ROK family protein; SPTR: C1YIR3 Glucokinase; TIGRFAM: glucokinase, ROK family; PFAM: ROK family; TIGRFAM: ROK family protein (putative glucokinase). (342 aa) |
| | acsA | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (656 aa) |
| | Ndas_5367 | COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR012999:IPR013027:IPR006258:IPR004099:IPR 000815:IPR001327:IPR016156; KEGG: sro:Sros_0616 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: C1YUH9 Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide [...] (467 aa) |
| | Ndas_5417 | COGs: COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit; InterPro IPR017596:IPR001017; KEGG: tfu:Tfu_0180 pyruvate dehydrogenase (lipoamide); PFAM: dehydrogenase E1 component; PRIAM: Pyruvate dehydrogenase (acetyl-transferring); SPTR: C1YUC9 Pyruvate dehydrogenase E1 component, alpha subunit; TIGRFAM: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; PFAM: Dehydrogenase E1 component; TIGRFAM: pyruvate dehydrogenase E1 component, alpha subunit. (371 aa) |
| | Ndas_5418 | Transketolase central region; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR009014:IPR005476:IPR005475:IPR015941; KEGG: tfu:Tfu_0181 putative branched-chain alpha keto acid dehydrogenase E1 beta subunit; PFAM: Transketolase central region; Transketolase domain protein; SMART: Transketolase central region; SPTR: C1YUC8 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (326 aa) |
| | Ndas_5419 | Catalytic domain of components of various dehydrogenase complexes; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR004167:IPR001078:IPR000089:IPR011053; KEGG: tfu:Tfu_0182 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: C1YUC7 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; PFAM: 2-oxoacid dehydrogenases acylt [...] (467 aa) |
| | Ndas_5544 | COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006099:IPR014348:IPR006158:IPR016176; KEGG: tfu:Tfu_2761 methylmalonyl-CoA mutase; PFAM: methylmalonyl-CoA mutase; PRIAM: Methylmalonyl-CoA mutase; SPTR: C1YPN3 Methylmalonyl-CoA mutase, N-terminal domain/subunit; PFAM: Methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase, heterodimeric type, beta chain. (644 aa) |
| | Ndas_5545 | COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterProIPR006158:IPR006099:IPR016176:IPR014348:IPR 006159:IPR006098; KEGG: tfu:Tfu_2762 methylmalonyl-CoA mutase; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein; PRIAM: Methylmalonyl-CoA mutase; SPTR: C1YPN2 Methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: Methylmalonyl-CoA mutase; B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase C-terminal domain. (738 aa) |
| | Ndas_5546 | LAO/AO transport system ATPase; COGs: COG1703 Putative periplasmic protein kinase ArgK and related GTPase of G3E family; InterPro IPR005129; KEGG: tfu:Tfu_2763 arginine/ornithine transport system ATPase; PFAM: ArgK protein; SPTR: C1YPN1 LAO/AO transport system ATPase; TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; TIGRFAM: LAO/AO transport system ATPase. (372 aa) |
