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Ndas_0025 | COGs: COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit; InterPro IPR017596:IPR001017; KEGG: art:Arth_3193 pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase E1 component; PRIAM: Pyruvate dehydrogenase (acetyl-transferring); SPTR: C1YR72 Pyruvate dehydrogenase E1 component, alpha subunit; TIGRFAM: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; PFAM: Dehydrogenase E1 component; TIGRFAM: pyruvate dehydrogenase E1 component, alpha subunit. (361 aa) | ||||
Ndas_0026 | Transketolase central region; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR009014:IPR005476:IPR005475:IPR015941; KEGG: art:Arth_3192 transketolase, central region; PFAM: Transketolase central region; Transketolase domain protein; SMART: Transketolase central region; SPTR: C1YR71 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (330 aa) | ||||
Ndas_0027 | COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterProIPR011053:IPR004167:IPR003016:IPR000089:IPR 001078; KEGG: aau:AAur_3154 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; PRIAM: Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; SPTR: C1YR70 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; PFAM: 2-oxoacid dehydroge [...] (466 aa) | ||||
sucC | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (393 aa) | ||||
sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (292 aa) | ||||
fumC | Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (462 aa) | ||||
mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa) | ||||
Ndas_0943 | COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterProIPR014276:IPR000089:IPR004167:IPR001078:IPR 011053:IPR003016; KEGG: tfu:Tfu_0993 2-oxoglutarate dehydrogenase E2 component; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; SPTR: C1YQF3 2-oxoglutarate dehydrogenase E2 component; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: 2-oxoacid dehydrogenases acyltransferase (cataly [...] (600 aa) | ||||
Ndas_0944 | COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027:IPR000815:IPR006258:IPR004099:IPR 016156:IPR012999; KEGG: tfu:Tfu_0994 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: C1YQF2 Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase. (458 aa) | ||||
Ndas_0999 | Aconitate hydratase domain protein; COGs: COG1048 Aconitase A; InterProIPR015931:IPR018136:IPR001030:IPR015932:IPR 000573:IPR015928; KEGG: ami:Amir_2132 aconitate hydratase 1; PFAM: aconitate hydratase domain protein; SPTR: C1YTQ9 Aconitase A; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase 1. (935 aa) | ||||
Ndas_1152 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1126 aa) | ||||
Ndas_2866 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (907 aa) | ||||
Ndas_3242 | Transketolase central region; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR005475:IPR005476:IPR015941:IPR009014; KEGG: aau:AAur_2539 pyruvate dehydrogenase E1 component, beta subunit; PFAM: Transketolase central region; Transketolase domain protein; SPTR: C1YSQ7 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (339 aa) | ||||
Ndas_3243 | 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); COGs: COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit; InterPro IPR001017; KEGG: art:Arth_2564 pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase E1 component; PRIAM: 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); SPTR: C1YSQ6 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component alpha subunit; PFAM: Dehydrogenase E1 component. (375 aa) | ||||
Ndas_3681 | COGs: COG0567 2-oxoglutarate dehydrogenase complex dehydrogenase (E1); InterPro IPR011603:IPR001078:IPR001017:IPR005475; KEGG: tfu:Tfu_0566 alpha-ketoglutarate decarboxylase; PFAM: Transketolase central region; dehydrogenase E1 component; catalytic domain of components of various dehydrogenase complexes; SPTR: C1YU54 2-oxoglutarate dehydrogenase E1 component; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Dehydrogenase E1 component; Transketolase, pyrimidine binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 [...] (1219 aa) | ||||
Ndas_3921 | COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterProIPR001041:IPR009051:IPR004489:IPR001450:IPR 012675:IPR012285:IPR006058:IPR017900:IPR017896; KEGG: tfu:Tfu_2451 succinate dehydrogenase/fumarate reductase iron-sulfur subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; ferredoxin; SPTR: C1YKT0 Succinate dehydrogenase subunit B; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. (248 aa) | ||||
Ndas_3922 | COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR015939:IPR011280:IPR003953:IPR004112; KEGG: tfu:Tfu_2452 succinate dehydrogenase flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PRIAM: Succinate dehydrogenase; SPTR: C1YKS9 Succinate dehydrogenase subunit A; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit, Bacillus subtilis subgroup. (648 aa) | ||||
Ndas_3923 | Succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; InterPro IPR011138; KEGG: tfu:Tfu_2453 succinate dehydrogenase subunit C; SPTR: C1YKS8 Succinate dehydrogenase subunit C; TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; PFAM: Succinate dehydrogenase/Fumarate reductase transmembrane subunit; TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family. (235 aa) | ||||
Ndas_3926 | COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR015939:IPR004112:IPR003953; KEGG: tcu:Tcur_1116 fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: C1YKS5 Succinate dehydrogenase subunit A; PFAM: domain; FAD binding domain. (680 aa) | ||||
Ndas_3927 | COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterProIPR001041:IPR006058:IPR012675:IPR012285:IPR 009051:IPR004489; KEGG: nfa:nfa56030 fumarate reductase iron-sulfur subunit; PFAM: ferredoxin; SPTR: C1YKS4 Succinate dehydrogenase subunit B; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. (263 aa) | ||||
Ndas_3960 | Isocitrate dehydrogenase, NADP-dependent; COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR004790:IPR019818:IPR001804; KEGG: tfu:Tfu_2568 isocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: C1YKN9 Isocitrate dehydrogenase (NADP); TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, eukaryotic type; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (405 aa) | ||||
sucD-2 | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (312 aa) | ||||
sucC-2 | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (395 aa) | ||||
pckG | Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (605 aa) | ||||
Ndas_4410 | COGs: COG0372 Citrate synthase; InterProIPR016141:IPR002020:IPR016142:IPR010953:IPR 019810; KEGG: rop:ROP_50580 citrate synthase; PFAM: Citrate synthase; SPTR: C1YGF6 Citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family. (429 aa) | ||||
pdhA | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (408 aa) | ||||
Ndas_4805 | Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (337 aa) | ||||
Ndas_4806 | Catalytic domain of components of various dehydrogenase complexes; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR004167:IPR001078:IPR000089:IPR011053; KEGG: tfu:Tfu_3051 pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: C1YP51 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; PFAM: 2-oxo [...] (436 aa) | ||||
Ndas_4932 | Aconitate hydratase; COGs: COG1048 Aconitase A; InterProIPR015931:IPR006250:IPR001030:IPR015932:IPR 000573:IPR015928; KEGG: svi:Svir_23930 aconitase; PFAM: aconitate hydratase domain protein; SPTR: C1YIW8 Aconitase; TIGRFAM: aconitate hydratase; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase, putative, Aquifex type. (652 aa) | ||||
Ndas_5088 | Thiamine pyrophosphate protein domain protein TPP-binding protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: tfu:Tfu_2675 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: C1YI77 2-oxoacid:ferredoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. (363 aa) | ||||
Ndas_5089 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002869:IPR009014:IPR002880; KEGG: tfu:Tfu_2674 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: C1YI76 2-oxoacid:ferredoxin oxidoreductase, alpha subunit; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase. (616 aa) | ||||
Ndas_5367 | COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR012999:IPR013027:IPR006258:IPR004099:IPR 000815:IPR001327:IPR016156; KEGG: sro:Sros_0616 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: C1YUH9 Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide [...] (467 aa) | ||||
Ndas_5417 | COGs: COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit; InterPro IPR017596:IPR001017; KEGG: tfu:Tfu_0180 pyruvate dehydrogenase (lipoamide); PFAM: dehydrogenase E1 component; PRIAM: Pyruvate dehydrogenase (acetyl-transferring); SPTR: C1YUC9 Pyruvate dehydrogenase E1 component, alpha subunit; TIGRFAM: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; PFAM: Dehydrogenase E1 component; TIGRFAM: pyruvate dehydrogenase E1 component, alpha subunit. (371 aa) | ||||
Ndas_5418 | Transketolase central region; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR009014:IPR005476:IPR005475:IPR015941; KEGG: tfu:Tfu_0181 putative branched-chain alpha keto acid dehydrogenase E1 beta subunit; PFAM: Transketolase central region; Transketolase domain protein; SMART: Transketolase central region; SPTR: C1YUC8 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (326 aa) | ||||
Ndas_5419 | Catalytic domain of components of various dehydrogenase complexes; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR004167:IPR001078:IPR000089:IPR011053; KEGG: tfu:Tfu_0182 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: C1YUC7 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; PFAM: 2-oxoacid dehydrogenases acylt [...] (467 aa) |