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Snas_0552 Snas_0552 Snas_0553 Snas_0553 sucC sucC sucD sucD Snas_0615 Snas_0615 Snas_0779 Snas_0779 fumC fumC acsA acsA Snas_1016 Snas_1016 Snas_1222 Snas_1222 Snas_1334 Snas_1334 Snas_1782 Snas_1782 Snas_2374 Snas_2374 Snas_2791 Snas_2791 Snas_2796 Snas_2796 Snas_2842 Snas_2842 Snas_3033 Snas_3033 Snas_3093 Snas_3093 Snas_3465 Snas_3465 pdhA pdhA Snas_3467 Snas_3467 Snas_3468 Snas_3468 Snas_3706 Snas_3706 Snas_4199 Snas_4199 Snas_4200 Snas_4200 Snas_4565 Snas_4565 Snas_4794 Snas_4794 Snas_5146 Snas_5146 Snas_5158 Snas_5158 Snas_5226 Snas_5226 Snas_5227 Snas_5227 Snas_5228 Snas_5228 Snas_5390 Snas_5390 Snas_5518 Snas_5518 Snas_5519 Snas_5519 Snas_6068 Snas_6068 Snas_6069 Snas_6069 Snas_6070 Snas_6070 Snas_6163 Snas_6163 Snas_6383 Snas_6383
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Snas_0552PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: afw:Anae109_1891 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. (617 aa)
Snas_0553PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: eba:ebA3150 2-oxoglutarate ferredoxin oxidoreductase subunit beta. (341 aa)
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (392 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa)
Snas_0615Lactate/malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (316 aa)
Snas_0779PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; glucose-inhibited division protein A; HI0933 family protein; KEGG: abc:ACICU_01738 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component. (463 aa)
fumCFumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
acsAacetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (655 aa)
Snas_1016PFAM: Citrate synthase; KEGG: mlo:mll3842 citrate synthase 2; Belongs to the citrate synthase family. (366 aa)
Snas_1222KEGG: rpt:Rpal_4362 isocitrate dehydrogenase, NADP- dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (405 aa)
Snas_1334PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: mxa:MXAN_0278 mercuric reductase, truncated. (452 aa)
Snas_1782PFAM: Aldehyde Dehydrogenase; KEGG: mxa:MXAN_5040 aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. (507 aa)
Snas_2374PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: hypothetical protein; K00467 lactate 2- monooxygenase. (421 aa)
Snas_2791PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; KEGG: cbd:CBUD_0736 pyruvate dehydrogenase [cytochrome]; Belongs to the TPP enzyme family. (576 aa)
Snas_2796PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP- binding; KEGG: mxa:MXAN_3654 thiamine pyrophosphate protein; Belongs to the TPP enzyme family. (597 aa)
Snas_2842PFAM: AMP-dependent synthetase and ligase; KEGG: eba:ebA1206 putative acetyl-coenzyme A synthetase. (566 aa)
Snas_3033Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (914 aa)
Snas_3093PFAM: Citrate synthase; KEGG: atu:Atu5306 citrate synthase 2; Belongs to the citrate synthase family. (378 aa)
Snas_3465PFAM: AMP-dependent synthetase and ligase; KEGG: gur:Gura_1608 acetyl-CoA synthetase. (598 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (326 aa)
Snas_3467Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (335 aa)
Snas_3468Dihydrolipoyllysine-residue(2-methylpropanoyl) transferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: dps:DPPB40 branched-chain alpha-keto acid dehydrogenase subunit E2. (406 aa)
Snas_3706L-lactate dehydrogenase (cytochrome); PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: azc:AZC_2267 L-lactate dehydrogenase. (409 aa)
Snas_4199TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; glucose-inhibited division protein A; FAD dependent oxidoreductase; HI0933 family protein; KEGG: mxa:MXAN_4219 alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase. (461 aa)
Snas_4200TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: sit:TM1040_3510 dihydrolipoamide succinyltransferase. (583 aa)
Snas_4565Malate dehydrogenase (oxaloacetate- decarboxylating); PFAM: malic protein NAD-binding; amino acid-binding ACT domain protein; malic protein domain protein; KEGG: sat:SYN_00517 NAD-dependent malic enzyme. (476 aa)
Snas_47942-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (919 aa)
Snas_5146TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component; catalytic domain of components of various dehydrogenase complexes; KEGG: gsu:GSU2449 alpha-ketoglutarate decarboxylase. (1225 aa)
Snas_5158Malate dehydrogenase (oxaloacetate- decarboxylating); PFAM: malic protein NAD-binding; malic protein domain protein; UBA/THIF-type NAD/FAD binding protein; KEGG: tau:Tola_0213 malate dehydrogenase (oxaloacetate-decarboxylating). (386 aa)
Snas_5226TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; KEGG: ank:AnaeK_2722 succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family. (232 aa)
Snas_5227KEGG: scl:sce6554 succinate dehydrogenase flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase. (646 aa)
Snas_5228PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: scl:sce6555 succinate dehydrogenase/fumarate reductase iron-sulfur subunit. (247 aa)
Snas_5390PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; KEGG: ade:Adeh_2206 FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (465 aa)
Snas_5518PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: bcm:Bcenmc03_3592 succinate dehydrogenase flavoprotein subunit. (641 aa)
Snas_5519TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; KEGG: mrd:Mrad2831_5989 succinate dehydrogenase and fumarate reductase iron-sulfur protein. (254 aa)
Snas_6068KEGG: gme:Gmet_2509 dehydrogenase, E1 component; TIGRFAM: pyruvate dehydrogenase (acetyl- transferring) E1 component, alpha subunit; PFAM: dehydrogenase E1 component. (385 aa)
Snas_6069PFAM: Transketolase central region; Transketolase domain protein; KEGG: ank:AnaeK_2034 transketolase domain protein. (328 aa)
Snas_6070PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: acp:A2cp1_2105 catalytic domain of components of various dehydrogenase complexes. (469 aa)
Snas_6163PFAM: CoA-binding domain protein; KEGG: bpt:Bpet0050 acyl-CoA synthetase. (442 aa)
Snas_6383Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (547 aa)
Your Current Organism:
Stackebrandtia nassauensis
NCBI taxonomy Id: 446470
Other names: S. nassauensis DSM 44728, Stackebrandtia nassauensis DSM 44728, Stackebrandtia nassauensis str. DSM 44728, Stackebrandtia nassauensis strain DSM 44728
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