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| | aroK | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (519 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (388 aa) |
| | Snas_3117 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: met:M446_6836 threonine dehydratase. (329 aa) |
| | Snas_3082 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: mca:MCA2968 D-isomer specific 2-hydroxyacid dehydrogenase family protein, putative. (317 aa) |
| | argH | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: pfo:Pfl01_2852 argininosuccinate lyase. (470 aa) |
| | argG | Argininosuccinate synthase; KEGG: esa:ESA_03807 hypothetical protein; TIGRFAM: argininosuccinate synthase; PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (402 aa) |
| | argR | Arginine repressor, ArgR; Regulates arginine biosynthesis genes. (186 aa) |
| | Snas_3066 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (319 aa) |
| | argD | TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; KEGG: acp:A2cp1_2878 acetylornithine and succinylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (401 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (297 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (382 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (352 aa) |
| | Snas_3049 | KEGG: ppd:Ppro_2466 asparagine synthase (glutamine- hydrolyzing); TIGRFAM: asparagine synthase (glutamine- hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II. (643 aa) |
| | Snas_3017 | PFAM: MaoC domain protein dehydratase; KEGG: par:Psyc_1308 hypothetical protein. (285 aa) |
| | Snas_2995 | PFAM: shikimate kinase; KEGG: hha:Hhal_2258 shikimate kinase. (153 aa) |
| | Snas_2949 | PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: rle:RL3511 putative dehydrogenase/oxidoreductase. (312 aa) |
| | Snas_2924 | Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (263 aa) |
| | Snas_2911 | PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: scl:sce8562 putative NADPH quinone oxidoreductase. (333 aa) |
| | Snas_2860 | PFAM: aminoglycoside phosphotransferase; KEGG: bba:Bd2045 homoserine kinase. (336 aa) |
| | Snas_2796 | PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP- binding; KEGG: mxa:MXAN_3654 thiamine pyrophosphate protein; Belongs to the TPP enzyme family. (597 aa) |
| | Snas_2792 | PFAM: ferredoxin-dependent glutamate synthase; KEGG: pag:PLES_14331 putative glutamate synthase, large subunit; Belongs to the glutamate synthase family. (526 aa) |
| | Snas_2791 | PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; KEGG: cbd:CBUD_0736 pyruvate dehydrogenase [cytochrome]; Belongs to the TPP enzyme family. (576 aa) |
| | Snas_2720 | PFAM: Uroporphyrinogen III synthase HEM4; transcriptional regulator domain protein; KEGG: aeh:Mlg_1707 uroporphyrinogen III synthase HEM4. (368 aa) |
| | Snas_2707 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: acp:A2cp1_1073 bifunctional deaminase- reductase domain protein. (192 aa) |
| | Snas_2701 | PFAM: protein of unknown function DUF161; KEGG: esa:ESA_02822 hypothetical protein. (227 aa) |
| | Snas_2654 | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: dal:Dalk_4445 peptidase M20. (443 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (281 aa) |
| | hisE | TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase; KEGG: sml:Smlt2169 putative bifunctional histidine biosynthesis bifunctional protein (phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase). (87 aa) |
| | Snas_2525 | Hypothetical protein; KEGG: sil:SPOA0339 HAD family hydrolase. (140 aa) |
| | Snas_2524 | PFAM: phosphopantetheine-binding; KEGG: eta:ETA_30060 hypothetical protein. (75 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (266 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (406 aa) |
| | trpC | PFAM: Indole-3-glycerol phosphate synthase; KEGG: afw:Anae109_0373 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. (269 aa) |
| | hisI | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (120 aa) |
| | Snas_2497 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mxa:MXAN_6034 enoyl-(acyl carrier protein) reductase. (260 aa) |
| | Snas_2472 | PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ank:AnaeK_3358 alcohol dehydrogenase zinc- binding domain protein. (314 aa) |
| | Snas_2438 | PFAM: protein of unknown function DUF201; ATP- dependent carboxylate-amine ligase domain protein ATP- grasp; KEGG: rhi:NGR234_331 Y4rH. (410 aa) |
| | Snas_2437 | PFAM: fumarate lyase; KEGG: bpl:BURPS1106A_2022 argininosuccinate lyase. (477 aa) |
| | Snas_2436 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bph:Bphy_7479 pyridoxal-5'-phosphate- dependent protein beta subunit. (344 aa) |
| | Snas_2432 | Amidohydrolase; KEGG: bbt:BBta_2982 putative amidohydrolase family protein; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein. (430 aa) |
| | Snas_2364 | PFAM: Methionine synthase vitamin-B12 independent; KEGG: mxa:MXAN_1973 hypothetical protein. (370 aa) |
| | Snas_2310 | PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: rme:Rmet_4293 alcohol dehydrogenase, zinc- binding. (310 aa) |
| | Snas_2276 | KEGG: pca:Pcar_2170 aIF-2BI family translation initiation factor; TIGRFAM: eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: initiation factor 2B related; Belongs to the eIF-2B alpha/beta/delta subunits family. (348 aa) |
| | Snas_2274 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: rle:RL0585 putative RibD family protein. (192 aa) |
| | pqqC | Coenzyme PQQ biosynthesis protein C; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ. (230 aa) |
| | Snas_2176 | PFAM: coenzyme PQQ synthesis D; KEGG: pag:PLES_33351 pyrroloquinoline quinone biosynthesis protein D. (88 aa) |
| | pqqE | Coenzyme PQQ biosynthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ). (350 aa) |
| | pqqB | Coenzyme PQQ biosynthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family. (294 aa) |
| | Snas_2135 | PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; KEGG: spe:Spro_0344 phosphoribosylglycinamide synthetase. (412 aa) |
| | Snas_1981 | PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: mrd:Mrad2831_1644 alcohol dehydrogenase. (328 aa) |
| | Snas_1967 | TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: LeuA allosteric (dimerisation) domain; pyruvate carboxyltransferase; KEGG: scl:sce3734 putative alpha- isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (538 aa) |
| | Snas_1914 | KEGG: reu:Reut_C5899 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. (352 aa) |
| | Snas_1905 | PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: msl:Msil_0872 alcohol dehydrogenase GroES domain protein. (297 aa) |
| | Snas_1904 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: afw:Anae109_3251 deaminase-reductase domain- containing protein. (200 aa) |
| | Snas_1817 | TIGRFAM: amidohydrolase; PFAM: peptidase M20; KEGG: tmz:Tmz1t_1306 amidohydrolase. (429 aa) |
| | Snas_1742 | PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: ank:AnaeK_3358 alcohol dehydrogenase zinc- binding domain protein. (314 aa) |
| | Snas_1735 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: mxa:MXAN_1250 riboflavin biosynthesis protein RibD domain-containing protein. (193 aa) |
| | Snas_1721 | PFAM: aldo/keto reductase; KEGG: mno:Mnod_0968 aldo/keto reductase. (276 aa) |
| | Snas_1705 | KEGG: scl:sce1139 hypothetical protein. (318 aa) |
| | Snas_1673 | PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: mlo:mll2594 quinone oxidoreductase. (316 aa) |
| | Snas_1558 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: afw:Anae109_2506 D-3-phosphoglycerate dehydrogenase. (324 aa) |
| | Snas_1556 | KEGG: dac:Daci_2801 Asp/Glu racemase. (218 aa) |
| | Snas_1555 | PFAM: aminoglycoside phosphotransferase; KEGG: ypb:YPTS_0017 serine/threonine protein kinase. (273 aa) |
| | Snas_1541 | TIGRFAM: cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: gur:Gura_0822 cysteine synthase. (316 aa) |
| | Snas_1540 | TIGRFAM: MoaD family protein; PFAM: thiamineS protein; KEGG: hch:HCH_02849 molybdopterin converting factor, small subunit. (91 aa) |
| | Snas_1539 | PFAM: Mov34/MPN/PAD-1 family protein; SMART: Mov34/MPN/PAD-1 family protein; KEGG: nmu:Nmul_A0971 Mov34/MPN/PAD-1. (145 aa) |
| | Snas_1526 | PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: ank:AnaeK_3358 alcohol dehydrogenase zinc- binding domain protein. (313 aa) |
| | Snas_1507 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ade:Adeh_3912 bifunctional deaminase- reductase-like. (186 aa) |
| | Snas_1499 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: pzu:PHZ_c0072 cystathionine gamma-lyase. (384 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (304 aa) |
| | Snas_1152 | PFAM: Beta-ketoacyl synthase; phosphopantetheine- binding; KEGG: mxa:MXAN_4528 polyketide synthase. (670 aa) |
| | Snas_1078 | PFAM: protein of unknown function DUF993; KEGG: mlo:mll3044 hypothetical protein. (376 aa) |
| | acpS | Holo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (122 aa) |
| | Snas_0943 | KEGG: scl:sce0438 cystathionine beta-synthase; TIGRFAM: cystathionine beta-synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; CBS domain containing protein; SMART: CBS domain containing protein. (454 aa) |
| | Snas_0886 | PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ank:AnaeK_3358 alcohol dehydrogenase zinc- binding domain protein. (315 aa) |
| | Snas_0817 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: shl:Shal_1937 pyridoxal-5'-phosphate- dependent protein beta subunit. (363 aa) |
| | Snas_0776 | Amidohydrolase; KEGG: nis:NIS_1768 N-acetyl-L-amino acid amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein. (391 aa) |
| | Snas_0772 | PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: NADPH:quinone reductase and related Zn- dependent oxidoreductases. (326 aa) |
| | Snas_0745 | PFAM: CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; glycosyl transferase family 2; KEGG: ppr:PBPRA2712 teichoic acid biosynthesis protein F. (1169 aa) |
| | Snas_0727 | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: ade:Adeh_3448 L-threonine ammonia-lyase. (411 aa) |
| | Snas_0659 | PFAM: thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP- binding; thiamine pyrophosphate protein TPP binding domain protein; KEGG: avn:Avin_50100 myo-inositol catabolism protein IolD; Belongs to the TPP enzyme family. (623 aa) |
| | Snas_0567 | KEGG: bur:Bcep18194_B3008 FAD-linked oxidoreductase; TIGRFAM: FAD-linked oxidoreductase; PFAM: D-arabinono-14-lactone oxidase; FAD linked oxidase domain protein. (435 aa) |
| | Snas_0559 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (366 aa) |
| | Snas_0557 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (369 aa) |
| | Snas_0494 | KEGG: ccs:CCNA_03599 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase dimerisation region; Semialdehyde dehydrogenase NAD - binding; Belongs to the aspartate-semialdehyde dehydrogenase family. (352 aa) |
| | Snas_0493 | TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; KEGG: aeh:Mlg_1480 aspartate kinase; Belongs to the aspartokinase family. (421 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (569 aa) |
| | bioD | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (219 aa) |
| | Snas_0471 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; aminotransferase class-III; aromatic amino acid beta- eliminating lyase/threonine aldolase; KEGG: mxa:MXAN_1258 8-amino-7-oxononanoate synthase. (370 aa) |
| | Snas_0470 | TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: dvl:Dvul_0689 adenosylmethionine-8-amino-7- oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (442 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (354 aa) |
| | Snas_0445 | TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: afw:Anae109_3605 threonine synthase. (418 aa) |
| | pat | Histidinol-phosphate aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (360 aa) |
| | Snas_0261 | TIGRFAM: NAD(P)H quinone oxidoreductase, PIG3 family; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: Os02g0805600; hypothetical protein; K00344 NADPH2:quinone reductase. (324 aa) |
| | Snas_0236 | PFAM: Prephenate dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: nmu:Nmul_A2195 prephenate dehydrogenase. (312 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (423 aa) |
| | Snas_0230 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: mlo:mlr0926 hypothetical protein. (184 aa) |
| | Snas_0226 | PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: mlo:mll7820 hypothetical protein. (294 aa) |
| | Snas_0213 | PFAM: carboxyl transferase; acetyl-CoA carboxylase alpha subunit; KEGG: acetyl-coA carboxylase; K01959 pyruvate carboxylase subunit A. (452 aa) |
| | panD-2 | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (141 aa) |
| | Snas_0194 | PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; phosphoribosylglycinamide synthetase; KEGG: plu:plu1218 hypothetical protein. (419 aa) |
| | Snas_0193 | PFAM: Beta-ketoacyl synthase; Acyl transferase; phosphopantetheine-binding; KEGG: mxa:MXAN_4415 non-ribosomal peptide synthetase/polyketide synthase. (1054 aa) |
| | Snas_0192 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Methyltransferase type 11; Methyltransferase type 12; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_3779 non-ribosomal peptide synthetase/polyketide synthase. (1914 aa) |
| | Snas_0188 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: pfl:PFL_2147 nonribosomal peptide synthetase. (1638 aa) |
| | panC | Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (273 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (150 aa) |
| | Snas_0044 | PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: atc:AGR_pAT_685 hypothetical protein. (296 aa) |
| | Snas_0013 | PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: mlo:mll2594 quinone oxidoreductase. (328 aa) |
| | pheA | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: ank:AnaeK_2061 prephenate dehydratase. (305 aa) |
| | Snas_6365 | KEGG: ade:Adeh_2687 hypothetical protein. (133 aa) |
| | Snas_6363 | TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; HAD-superfamily hydrolase, subfamily IB (PSPase- like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pmy:Pmen_4219 HAD family hydrolase. (272 aa) |
| | Snas_6219 | TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; HAD-superfamily hydrolase, subfamily IB (PSPase- like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: afw:Anae109_1214 HAD family hydrolase. (289 aa) |
| | Snas_6218 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (291 aa) |
| | Snas_6217 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (123 aa) |
| | Snas_6216 | TIGRFAM:2-amino-4-hydroxy-6- hydroxymethyldihydropter idinepyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin- pyrophosphokinase HPPK; KEGG: smt:Smal_1516 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (169 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (422 aa) |
| | Snas_6110 | PFAM: GCN5-related N-acetyltransferase; KEGG: acp:A2cp1_1057 GCN5-related N- acetyltransferase. (338 aa) |
| | Snas_6101 | PFAM: dihydrodipicolinate synthetase; KEGG: rec:RHECIAT_CH0000678 putative N- acetylneuraminate lyase subunit protein; Belongs to the DapA family. (317 aa) |
| | Snas_6073 | PFAM: GCN5-related N-acetyltransferase; KEGG: vpa:VPA1596 putative acetyltransferase. (168 aa) |
| | Snas_5956 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: mlo:mll8258 hypothetical protein. (188 aa) |
| | ectC | Ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (139 aa) |
| | Snas_5812 | Diaminobutyrate/2-oxoglutarate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (419 aa) |
| | Snas_5803 | KEGG: mxa:MXAN_7473 hypothetical protein. (364 aa) |
| | Snas_5799 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: mxa:MXAN_1250 riboflavin biosynthesis protein RibD domain-containing protein. (191 aa) |
| | Snas_5778 | PFAM: aminoglycoside phosphotransferase. (316 aa) |
| | Snas_5774 | KEGG: met:M446_1342 amidase; TIGRFAM: amidase, hydantoinase/carbamoylase family; PFAM: peptidase M20. (399 aa) |
| | Snas_5770 | PFAM: protein of unknown function DUF540; KEGG: apa:APP7_1355 putative sulfate transport protein CysZ. (251 aa) |
| | Snas_5752 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: rhi:NGR_c15100 putative glycerate dehydrogenase. (333 aa) |
| | Snas_5750 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: lpp:lpp1969 hypothetical protein. (176 aa) |
| | Snas_5741 | KEGG: ccs:CCNA_03063 hypothetical protein. (315 aa) |
| | Snas_5735 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: oan:Oant_1327 bifunctional deaminase- reductase domain protein. (203 aa) |
| | Snas_5731 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: sme:SMc02439 hypothetical protein. (201 aa) |
| | Snas_5725 | Agmatinase; KEGG: bch:Bcen2424_5284 putative agmatinase; TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; Belongs to the arginase family. (346 aa) |
| | Snas_5707 | PFAM: aminotransferase class IV; KEGG: scl:sce0176 branched-chain-amino-acid transaminase. (281 aa) |
| | Snas_5678 | Nucleotide sugar dehydrogenase; KEGG: sit:TM1040_3775 UDP-glucose 6-dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP- glucose/GDP-mannose dehydrogenase dimerisation; UDP- glucose/GDP-mannose dehydrogenase. (474 aa) |
| | Snas_5667 | Hypothetical protein. (551 aa) |
| | Snas_5666 | KEGG: aha:AHA_2671 hypothetical protein. (569 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (468 aa) |
| | Snas_5546 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: pca:Pcar_1451 homoserine dehydrogenase. (434 aa) |
| | Snas_5545 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (351 aa) |
| | dapD | Putative 2,3,4, 5-tetrahydropyridine-2- carboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (307 aa) |
| | Snas_5500 | TIGRFAM: succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: afw:Anae109_3942 dipeptidase. (358 aa) |
| | Snas_5453 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: rle:RL1220 hypothetical protein. (210 aa) |
| | Snas_5367 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: atc:AGR_C_2241 hypothetical protein. (206 aa) |
| | Snas_5268 | KEGG: mlo:mll8388 hypothetical protein. (194 aa) |
| | Snas_5205 | Hypothetical protein. (265 aa) |
| | Snas_5194 | TIGRFAM: histidinol-phosphate phosphatase; PFAM: inositol monophosphatase; KEGG: ank:AnaeK_2573 inositol-phosphate phosphatase. (266 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (431 aa) |
| | egtD | Methyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. (319 aa) |
| | egtC | Glutamine amidotransferase class-II; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. (245 aa) |
| | egtB | Protein of unknown function DUF323; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. (437 aa) |
| | egtA | Glutamate--cysteine ligase GCS2; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. (410 aa) |
| | Snas_5155 | PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: xcv:XCV2170 putative oxidoreductase. (321 aa) |
| | Snas_5117 | Hypothetical protein. (122 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (253 aa) |
| | Snas_5095 | PFAM: Xylose isomerase domain protein TIM barrel; Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: pol:Bpro_4496 4-hydroxyphenylpyruvate dioxygenase. (604 aa) |
| | aroE | Shikimate dehydrogenase substrate binding domain protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (310 aa) |
| | metE | 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (749 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (276 aa) |
| | Snas_5038 | Phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: bbt:BBta_3493 3-deoxy-D-arabinoheptulosonate- 7-phosphate synthase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase class II. (464 aa) |
| | Snas_5027 | KEGG: azc:AZC_4340 5,10-methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (298 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (470 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (198 aa) |
| | Snas_4933 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: hypothetical protein. (398 aa) |
| | Snas_4896 | TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: gur:Gura_2228 glutamine synthetase, type I. (479 aa) |
| | lipA | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (311 aa) |
| | Snas_4861 | Amidohydrolase; KEGG: dvm:DvMF_1012 amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein. (396 aa) |
| | Snas_4827 | KEGG: reu:Reut_C5899 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. (349 aa) |
| | panB | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (280 aa) |
| | Snas_4822 | PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: sat:SYN_01628 glutamine synthetase. (448 aa) |
| | Snas_4811 | 3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (404 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (82 aa) |
| | fabH | 3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (315 aa) |
| | Snas_4808 | KEGG: cja:CJA_1675 malonyl CoA-acyl carrier protein transacylase. (307 aa) |
| | Snas_4798 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: sil:SPO3341 threonine dehydratase. (336 aa) |
| | Snas_4772 | PFAM: GCN5-related N-acetyltransferase; KEGG: avi:Avi_2225 acetyltransferase. (166 aa) |
| | Snas_4764 | PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: scl:sce1535 alcohol dehydrogenase. (324 aa) |
| | Snas_4716 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bph:Bphy_7479 pyridoxal-5'-phosphate- dependent protein beta subunit. (388 aa) |
| | Snas_4666 | Beta-Ala-His dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: mxa:MXAN_6011 M20 family peptidase. (455 aa) |
| | Snas_4631 | Gluconolactonase; PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: vei:Veis_1531 SMP-30/gluconolaconase/LRE domain-containing protein. (302 aa) |
| | kynU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (421 aa) |
| | Snas_4592 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein; SMART: Rhodanese domain protein; KEGG: hch:HCH_02851 molybdopterin/thiamine biosynthesis family protein. (392 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (271 aa) |
| | Snas_4519 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Male sterility domain; phosphopantetheine-binding; NAD- dependent epimerase/dehydratase; condensation domain protein; KEGG: scl:sce3888 nonribosomal peptide synthetase. (1478 aa) |
| | Snas_4518 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (347 aa) |
| | Snas_4499 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1173 aa) |
| | Snas_4361 | PFAM: thiamineS protein; KEGG: mxa:MXAN_4067 ThiS family protein. (94 aa) |
| | ilvD | KEGG: rpd:RPD_3804 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (614 aa) |
| | Snas_4356 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP- binding; KEGG: ade:Adeh_1978 acetolactate synthase, large subunit. (597 aa) |
| | Snas_4355 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: sfu:Sfum_3022 acetolactate synthase, small subunit. (172 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (336 aa) |
| | Snas_4312 | KEGG: dal:Dalk_3379 D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein. (533 aa) |
| | Snas_4289 | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: sat:SYN_00088 3-isopropylmalate dehydrogenase. (346 aa) |
| | Snas_4288 | TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; KEGG: bra:BRADO6039 branched-chain amino acid aminotransferase. (365 aa) |
| | Snas_4268 | PFAM: GCN5-related N-acetyltransferase; KEGG: cvi:CV_4321 hypothetical protein. (151 aa) |
| | Snas_4243 | PFAM: asparagine synthase; KEGG: rsq:Rsph17025_1965 asparagine synthase. (630 aa) |
| | Snas_4179 | PFAM: purine or other phosphorylase family 1; KEGG: nmu:Nmul_A0542 response regulator receiver domain-containing protein. (351 aa) |
| | nadA | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (388 aa) |
| | Snas_4138 | TIGRFAM: crotonyl-CoA reductase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: dds:Ddes_1332 crotonyl-CoA reductase. (443 aa) |
| | Snas_4135 | PFAM: Acyl transferase; short-chain dehydrogenase/reductase SDR; Beta-ketoacyl synthase; Alcohol dehydrogenase GroES domain protein; KR domain protein; Erythronolide synthase docking; Alcohol dehydrogenase zinc-binding domain protein; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: eca:ECA0603 type I polyketide synthase. (2108 aa) |
| | Snas_4134 | PFAM: Acyl transferase; Beta-ketoacyl synthase; Erythronolide synthase docking; phosphopantetheine- binding; KEGG: pst:PSPTO_4687 coronafacic acid polyketide synthetase II. (1101 aa) |
| | Snas_4133 | PFAM: Acyl transferase; Beta-ketoacyl synthase; Erythronolide synthase docking; Thioesterase; phosphopantetheine-binding; KEGG: eca:ECA0603 type I polyketide synthase. (1305 aa) |
| | Snas_4132 | PFAM: Acyl transferase; KR domain protein; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: pst:PSPTO_4686 coronafacic acid polyketide synthase I. (2277 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (348 aa) |
| | Snas_4116 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (308 aa) |
| | Snas_4115 | PFAM: inositol monophosphatase; KEGG: ade:Adeh_1287 histidinol-phosphate phosphatase. (288 aa) |
| | Snas_4069 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: rhi:NGR_b17460 phosphoglycerate dehydrogenase. (347 aa) |
| | Snas_4055 | PFAM: Beta-ketoacyl synthase; Acyl transferase; phosphopantetheine-binding; KEGG: mxa:MXAN_4415 non-ribosomal peptide synthetase/polyketide synthase. (974 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (429 aa) |
| | hisC | TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: bur:Bcep18194_C7445 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (361 aa) |
| | hisB | PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: bid:Bind_0249 imidazoleglycerol-phosphate dehydratase. (203 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (202 aa) |
| | hisA | Bifunctional HisA/TrpF protein; KEGG: plu:plu0797 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4- carboxamide isomerase; TIGRFAM: bifunctional HisA/TrpF protein; PFAM: histidine biosynthesis protein. (243 aa) |
| | hisF | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (254 aa) |
| | Snas_3875 | PFAM: Shikimate dehydrogenase substrate binding domain protein; Shikimate/quinate 5-dehydrogenase; KEGG: cak:Caul_5013 shikimate 5-dehydrogenase; Belongs to the shikimate dehydrogenase family. (327 aa) |
| | Snas_3807 | PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: afw:Anae109_0854 glutamate synthase (ferredoxin). (1502 aa) |
| | Snas_3806 | TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: scl:sce5061 glutamate synthase (NADPH). (488 aa) |
| | Snas_3796 | PFAM: GCN5-related N-acetyltransferase; KEGG: oan:Oant_3628 GCN5-related N- acetyltransferase. (151 aa) |
| | Snas_3735 | PFAM: Orn/DAP/Arg decarboxylase 2; alanine racemase domain protein; KEGG: rso:RS00881 diaminopimelate decarboxylase protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (388 aa) |
| | Snas_3694 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: ank:AnaeK_1068 bifunctional deaminase- reductase domain protein. (201 aa) |
| | Snas_3571 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: rec:RHECIAT_PC0000110 putative riboflavin biosynthesis protein. (197 aa) |
| | Snas_3554 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: rec:RHECIAT_PC0000110 putative riboflavin biosynthesis protein. (215 aa) |
| | Snas_3516 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: ara:Arad_4426 threonine dehydratase protein. (316 aa) |
| | Snas_3505 | PFAM: phosphopantetheine-binding; KEGG: bbt:BBta_4801 hypothetical protein. (80 aa) |
| | Snas_3493 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (336 aa) |
| | Snas_3403 | PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: rme:Rmet_4293 alcohol dehydrogenase, zinc- binding. (310 aa) |
| | Snas_3375 | KEGG: hypothetical protein. (345 aa) |
| | Snas_3374 | TIGRFAM: acetylornithine deacetylase or succinyl- diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: aeh:Mlg_1722 acetylornithine deacetylase. (424 aa) |
| | Snas_3349 | KEGG: rpe:RPE_3491 hypothetical protein. (559 aa) |
| | Snas_3347 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (356 aa) |
| | Snas_3340 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: rec:RHECIAT_PC0000110 putative riboflavin biosynthesis protein. (185 aa) |
| | Snas_3316 | TIGRFAM: ornithine aminotransferase; PFAM: aminotransferase class-III; KEGG: bid:Bind_2814 ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (396 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (545 aa) |
| | Snas_3256 | PFAM: GCN5-related N-acetyltransferase; KEGG: cak:Caul_3647 GCN5-related N- acetyltransferase. (298 aa) |
| | Snas_3172 | PFAM: aminoglycoside phosphotransferase; KEGG: scl:sce4958 hypothetical protein. (257 aa) |
| | carB | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl- phosphate synthetase large chain domain protein; KEGG: gur:Gura_1864 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. (1105 aa) |
| | carA | KEGG: dol:Dole_0120 carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family. (412 aa) |
| | aroQ | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (145 aa) |
